EP0920319A4 - Antagonistes de la gonadoliberine - Google Patents

Antagonistes de la gonadoliberine

Info

Publication number
EP0920319A4
EP0920319A4 EP97926706A EP97926706A EP0920319A4 EP 0920319 A4 EP0920319 A4 EP 0920319A4 EP 97926706 A EP97926706 A EP 97926706A EP 97926706 A EP97926706 A EP 97926706A EP 0920319 A4 EP0920319 A4 EP 0920319A4
Authority
EP
European Patent Office
Prior art keywords
antagonists
releasing hormone
gonadotropin releasing
gonadotropin
hormone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97926706A
Other languages
German (de)
English (en)
Other versions
EP0920319A1 (fr
Inventor
Mark Goulet
Robert J Devita
Matthew J Wyvratt Jr
Jonathan R Young
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9613525.6A external-priority patent/GB9613525D0/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of EP0920319A1 publication Critical patent/EP0920319A1/fr
Publication of EP0920319A4 publication Critical patent/EP0920319A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP97926706A 1996-05-20 1997-05-16 Antagonistes de la gonadoliberine Withdrawn EP0920319A4 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US1715196P 1996-05-20 1996-05-20
US17151P 1996-05-20
GBGB9613525.6A GB9613525D0 (en) 1996-06-27 1996-06-27 Antagonists of gonadotropin releasing hormone
GB9613525 1996-06-27
PCT/US1997/008782 WO1997044041A1 (fr) 1996-05-20 1997-05-16 Antagonistes de la gonadoliberine

Publications (2)

Publication Number Publication Date
EP0920319A1 EP0920319A1 (fr) 1999-06-09
EP0920319A4 true EP0920319A4 (fr) 2002-05-02

Family

ID=26309582

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97926706A Withdrawn EP0920319A4 (fr) 1996-05-20 1997-05-16 Antagonistes de la gonadoliberine

Country Status (5)

Country Link
EP (1) EP0920319A4 (fr)
JP (1) JP2000511186A (fr)
AU (1) AU712019B2 (fr)
CA (1) CA2254974A1 (fr)
WO (1) WO1997044041A1 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2254756A1 (fr) * 1996-05-20 1997-11-27 Mark Goulet Antagonistes de la gonadoliberine
US6346534B1 (en) 1998-09-23 2002-02-12 Neurocrine Biosciences, Inc. Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
US6537998B1 (en) 1999-10-15 2003-03-25 Neurocrine Biosciences, Inc. Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
US6608197B2 (en) 2000-01-25 2003-08-19 Neurocrine Biosciences, Inc. Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
EP1886999A3 (fr) * 2000-09-22 2008-03-12 N.V. Organon Composant hétéroaromatique bicyclique
US6583153B2 (en) 2000-12-12 2003-06-24 Ortho-Mcneil Pharmaceutical, Inc. 7-heterocyclyl quinoline and thieno[2,3-b]yridine derivatives useful as antagonists of gonadotropin releasing hormone
DE10108271A1 (de) 2001-02-21 2002-08-22 Schering Ag Chinolin-, Isochinolin- und Phthalazinderivate als Antagonisten des Gonadotropin freisetzenden Hormons
WO2002066437A1 (fr) * 2001-02-21 2002-08-29 Zentaris Gmbh Derives de quinoleine, d'isoquinoleine et de phthalazine utilises comme antagonistes de la gonadoliberine
AU2002324586B2 (en) 2001-08-02 2008-04-24 Neurocrine Biosciences, Inc. 1,3,5-triazine-2,4,6-triones, preparation and use as gonadotropin-releasing hormone receptor antagonists
AU2002321878A1 (en) 2001-08-02 2003-02-17 Neurocrine Biosciences, Inc. Pyridinone and pyridazinone derivatives as gonadotropin-releasing hormone receptor antagonists
EP1412363A1 (fr) 2001-08-02 2004-04-28 Neurocrine Biosciences, Inc. Antagonistes du recepteur de l'hormone liberatrice de la gonadotropine
JP2005500352A (ja) 2001-08-02 2005-01-06 ニューロクライン バイオサイエンシーズ， インコーポレイテッド ゴナドトロピン放出ホルモンレセプター（ＧｎＲＨ）アンタゴニストとしての１，２，４−トリアジン−３，５−ジオン
EP1411945A1 (fr) 2001-08-02 2004-04-28 Neurocrine Biosciences, Inc. Pyridin-4-ones substituees et leur utilisation en tant qu'antagonistes du recepteur de l'hormone de liberation de la gonadotrophine
GB0223730D0 (en) * 2002-10-11 2002-11-20 Novartis Ag Organic compounds
GB0307777D0 (en) 2003-04-04 2003-05-07 Medical Res Council Conjugate compounds
GB0412769D0 (en) 2004-06-08 2004-07-07 Novartis Ag Organic compounds
TW201130854A (en) 2009-12-22 2011-09-16 Bayer Schering Pharma Ag Pyridinone derivatives and pharmaceutical compositions thereof
WO2012175514A1 (fr) 2011-06-21 2012-12-27 Bayer Intellectual Property Gmbh Dérivés de pyridinone et compositions pharmaceutiques les contenant

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0679642A1 (fr) * 1994-04-28 1995-11-02 Takeda Chemical Industries, Ltd. Dérivés hétérocycliques condensés, leur préparation et utilisation
WO1997044037A1 (fr) * 1996-05-20 1997-11-27 Merck & Co., Inc. Antagonistes de la gonadoliberine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4578381A (en) * 1982-07-05 1986-03-25 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
GB9125515D0 (en) * 1991-11-29 1992-01-29 Merck Sharp & Dohme Therapeutic agents
US5656643A (en) * 1993-11-08 1997-08-12 Rhone-Poulenc Rorer Pharmaceuticals Inc. Bis mono-and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0679642A1 (fr) * 1994-04-28 1995-11-02 Takeda Chemical Industries, Ltd. Dérivés hétérocycliques condensés, leur préparation et utilisation
WO1997044037A1 (fr) * 1996-05-20 1997-11-27 Merck & Co., Inc. Antagonistes de la gonadoliberine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9744041A1 *

Also Published As

Publication number Publication date
JP2000511186A (ja) 2000-08-29
AU712019B2 (en) 1999-10-28
AU3141197A (en) 1997-12-09
CA2254974A1 (fr) 1997-11-27
EP0920319A1 (fr) 1999-06-09
WO1997044041A1 (fr) 1997-11-27

Similar Documents

Publication Publication Date Title
EP0986385A4 (fr) Antagonistes de gonadoliberine
EP0918522A4 (fr) Antagonistes de la gonadoliberine
IL124554A0 (en) Antagonists of gonadotropin releasing hormone
IL124613A0 (en) Antagonists of gonadotropin releasing hormone
AU3008997A (en) Antagonists of gonadotropin releasing hormone
EP0868178A4 (fr) Antagonistes de la gonadoliberine
EP0986557A4 (fr) Antagonistes de la gonadoliberine
ZA9610535B (en) Antagonists of gonadotropin releasing hormone.
ZA9610536B (en) Antagonists of gonadotropin releasing hormone.
EP1067930A4 (fr) Antagonistes de l'hormone liberant la gonadotropine (gnrh)
EP1011667A4 (fr) Antagonistes de l'hormone de liberation de la gonadotrophine
EP0901471A4 (fr) Antagonistes de la gonadoliberine
EP0920319A4 (fr) Antagonistes de la gonadoliberine
EP1027046A4 (fr) Antagonistes de l'hormone de liberation de la gonadothrophine
EP1049472A4 (fr) Antagonistes de la gonadoliberine
AU4834900A (en) Antagonists of gonadotropin releasing hormone
EP1062215A4 (fr) Antagonistes de l'hormone de liberation de la gonadotrophine
GB9612084D0 (en) Antagonists of gonadotropin releasing hormone
GB9603344D0 (en) Antagonists of gonadotropin releasing hormone
GB9613525D0 (en) Antagonists of gonadotropin releasing hormone
GB9603242D0 (en) Antagonists of gonadotropin releasing hormone
GB9613459D0 (en) Antagonists of gonadotropin releasing hormone
GB9603369D0 (en) Antagonists of gonadotropin releasing hormone
GB9603370D0 (en) Antagonists of gonadotropin releasing hormone
GB9612796D0 (en) Antagonists of gonadotropin releasing hormone

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19981221

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

A4 Supplementary search report drawn up and despatched

Effective date: 20020320

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

RIC1 Information provided on ipc code assigned before grant

Free format text: 7A 61K 31/505 A, 7A 61K 31/47 B, 7C 07D 403/14 B, 7C 07D 409/14 B

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20011204