EP1066880A1 - Enceinte de travail munie de moyens de recyclage de l'atmosphère - Google Patents

Enceinte de travail munie de moyens de recyclage de l'atmosphère Download PDF

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Publication number
EP1066880A1
EP1066880A1 EP00401934A EP00401934A EP1066880A1 EP 1066880 A1 EP1066880 A1 EP 1066880A1 EP 00401934 A EP00401934 A EP 00401934A EP 00401934 A EP00401934 A EP 00401934A EP 1066880 A1 EP1066880 A1 EP 1066880A1
Authority
EP
European Patent Office
Prior art keywords
bypass loop
tank
door
atmosphere
loop
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00401934A
Other languages
German (de)
English (en)
French (fr)
Inventor
Norbert Marchal
Laurent Mimaud
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jouan SA
Original Assignee
Jouan SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jouan SA filed Critical Jouan SA
Publication of EP1066880A1 publication Critical patent/EP1066880A1/fr
Withdrawn legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L1/00—Enclosures; Chambers
    • B01L1/04—Dust-free rooms or enclosures

Definitions

  • the present invention relates to a working enclosure, of the type comprising a working chamber whose walls define a confinement space specific to the implementation of a work and a bypass loop outdoor for recycling the atmosphere of the containment space, which branch loop ends at both ends in space containment and includes means for setting the atmosphere in motion in the bypass loop.
  • Such working enclosures are commonly thermostatically controlled, so that the containment space be maintained at a constant temperature.
  • ancillary devices are commonly used to ensure high relative humidity value.
  • enclosures are used for example for work in a controlled atmosphere. It can be for example the culture of animal cells or embryos. In this case, the CO 2 and water vapor content of the atmosphere of the confinement space is checked in particular.
  • the enclosure may be contaminated by unwanted germs growing in the space of confinement.
  • the recycling of the atmosphere of the enclosure, through a loop external bypass provided for this purpose, allows the atmosphere to be treated continuous, and in particular to filter the atmosphere of the enclosure.
  • a fan or pump is fitted in the bypass for the circulation of the atmosphere.
  • a filter is provided at the inlet end of the pipe constituting the loop of derivation considering the normal direction of flow of the atmosphere in the loop. It ensures the retention of contaminating elements during the circulation of the atmosphere of the enclosure.
  • Such an enclosure functions satisfactorily as long as the fan or the pump is not stopped and the atmosphere is circulating through of the bypass loop.
  • the object of the invention is to propose a working enclosure limiting the requirements for manual decontamination of the containment space and bypass loop.
  • the invention relates to a working enclosure, of the type aforementioned, characterized in that it comprises filtration members arranged at both ends of said bypass loop.
  • the working enclosure 10 shown in FIG. 1, comprises a working chamber 12 received in a thermostatically controlled box 14.
  • the working chamber defines a confinement space 16 suitable for carrying out work, such as the incubation of cells or embryos.
  • the enclosure 10 is equipped with means for controlling the atmosphere of the confinement space and in particular its CO 2 and water vapor content.
  • the working chamber 12 consists of a tank 17, substantially parallelepiped and one of the faces of which is open. This face, denoted 18, is closed by a hinged door 20. The latter is suitable for sealing an access opening to the containment space 16.
  • the tank 17 partially delimiting the working chamber 12 is received completely in the thermostat-controlled box 14.
  • the latter forms an envelope 22 all around the working chamber 12, except for the face open 18 of it.
  • the envelope 22, thus delimited, is filled with a liquid coolant, such as water.
  • the solid walls of the tank 17 are in contact with the heat transfer liquid.
  • Means 24 for regulating the temperature of the heat transfer liquid are installed in the box thermostatically controlled 14.
  • the door 20 is articulated on the thermostatically controlled box 14 via of hinges 26.
  • the door can be moved between a position allowing access to the containment space 16 through the open face 18 of the working chamber and a closed position of the face 18.
  • the door 20 comprises a frame delimited by a waterproof box 28 filled a heat transfer fluid such as water.
  • Means 30 for regulating the temperature of the heat transfer fluid, such as heating resistors, are provided inside the box 28.
  • the box 28 is thus thermostatically controlled and can advantageously be kept at the same temperature as the envelope 22.
  • the door 20 comprises, along its face opposite the chamber 12, a plate 32 intended for sealing off the confinement space 16.
  • the plate 32 has dimensions slightly greater than the open face 18 of the tank. It is adapted to apply according to the edges of the tank to close it tightly. For this purpose, a joint device is advantageously provided.
  • a bypass loop 40 for recycling the contained atmosphere in the containment space 16, is integrated inside the door 20. This bypass loop ends at both ends inside from the working chamber 12, through the open face 18 thereof.
  • the bypass loop 40 extends from an inlet opening 42 up to an outlet opening 44, both formed in the plate shutter 32.
  • a suction mouth 46 is provided behind the opening inlet 42. This is extended by a pipe 48 extending along the length of the door inside the box 28. Thus, the pipe 48 is immersed in the heat transfer fluid.
  • the bypass loop opens at the outlet end 44 via a rejection mouth 50.
  • a fan 52, a compressor or a pump is mounted inside of the suction mouth 46 to ensure circulation of the atmosphere through the bypass loop 40.
  • filtration members 54, 56 are provided, respectively, at the input and output ends of the bypass loop 40.
  • These filtration elements are identical and are formed, for example, of filters known as HEPA, initials for "High Efficiency Particles Air ".
  • the filters are for example sieves with an opening diameter of 0.2 ⁇ m.
  • the filtration members 54 and 56 are arranged in the thickness of the plate 32 and thus ensure the continuity of this wall of the chamber.
  • bypass loop 40 equipped with the fan 52, allows the atmosphere contained in the space to circulate continuously confinement. So the contaminating particles in the atmosphere are retained by the filter member 54 mounted at the inlet 42 of the bypass loop.
  • the filter member 56 does not participate properly talk to the filtration of the atmosphere of the enclosure.
  • the filter 56 prevents contaminants do not enter the bypass loop 40 through the outlet opening 44.
  • FIGS. 2 and 3 the elements identical or analogous to those of FIG. 1 are designated by the same reference numbers.
  • bypass loop 70 is not placed in the shutter door containment space 16. This door is not shown and extends forward parallel to the plane of the figure.
  • Bypass loop 70 is disposed in the envelope 22 delimited by the box 14 and the work 12.
  • bypass loop 70 extends along a wall external lateral 72 of the box.
  • Bypass loop 70 opens through a side wall 73 of the tank.
  • this wall is pierced an entry opening 74 intended to collect the contained atmosphere in the containment space and an outlet opening 76 intended to the reintroduction of the filtered atmosphere.
  • the openings 74 and 76 are each provided with a filtration member. noted respectively 78 and 80.
  • These filtration elements constituted by example of a sieve with a diameter of 0.2 ⁇ m, are integrated into the thickness of the wall 73.
  • the bypass loop comprises a suction mouth 82 disposed downstream of the filter 78, a transport line 84 and a discharge mouth 86 opening into space confinement 16 through the filter 76.
  • a fan is mounted in the bypass loop. It has a rotor 88 disposed in line 84, downstream of the suction mouth 82.
  • the rotor 88 is rotated by an electric motor 90 arranged, at outside of the thermostatted box 14 and inside an auxiliary box 92.
  • the filter 78 ensures the capture of contaminants during the continuous circulation of the atmosphere workspace through the bypass loop 70.
  • the filter 80 prevents contaminants from penetrate the bypass loop 70, thus avoiding having to decontaminate the bypass loop 70 before a new use of the enclosure.
  • the bypass loop is designated by the general reference 100. It includes a transport 102 which connects a suction mouth 104 to a rejection mouth 106. These open into space 16 through a side wall 108 in which are formed openings 110, 112. These openings are each fitted with a filter 114, 116.
  • Line 102 does not extend inside the envelope 22 filled with heat transfer fluid, but in a adjacent thermostated zone 120. This zone 120 is delimited by a box 122 and is filled with air.
  • Heating resistors 124 are arranged inside the box 122, in order to maintain the temperature in zone 120 at a temperature substantially equal to that of the envelope 22.
  • a fan rotor 130 is mounted in the bypass loop 100. Its drive motor, noted 132, is located inside the thermostat zone 120.
  • the filter 116 prevents contaminants from entering the bypass loop 100 when stopping the fan.
  • the transport line 102 being disposed not in the envelope 22 filled with heat transfer liquid but in a thermostatically controlled area adjacent to the air, maintenance operations on the loop derivation are facilitated.
  • zone 120 also being thermostatically controlled, transporting the atmosphere from the containment space during of its filtration through line 102 does not cause variation temperature, thereby reducing the risk of possible condensation.

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  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Ventilation (AREA)
EP00401934A 1999-07-06 2000-07-05 Enceinte de travail munie de moyens de recyclage de l'atmosphère Withdrawn EP1066880A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9908716 1999-07-06
FR9908716A FR2795977B1 (fr) 1999-07-06 1999-07-06 Enceinte de travail munie de moyens de recyclage de l'atmosphere

Publications (1)

Publication Number Publication Date
EP1066880A1 true EP1066880A1 (fr) 2001-01-10

Family

ID=9547765

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00401934A Withdrawn EP1066880A1 (fr) 1999-07-06 2000-07-05 Enceinte de travail munie de moyens de recyclage de l'atmosphère

Country Status (4)

Country Link
US (1) US6446716B1 (ja)
EP (1) EP1066880A1 (ja)
JP (1) JP2001074285A (ja)
FR (1) FR2795977B1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010004279A2 (en) * 2008-07-08 2010-01-14 Ruskinn Life Sciences Limited Laboratory apparatus for a controlled environment

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6732787B1 (en) * 2003-03-10 2004-05-11 Avaya Technology Corp. Cabinet upgrade system for in-service telecommunications cabinets
JP2006183929A (ja) * 2004-12-27 2006-07-13 Hokkaido Univ クリーンユニット−プロセス装置融合システム、クリーンユニットシステム、クリーンユニット、連結クリーンユニット、ポータブルクリーンユニットおよびプロセス方法
JP3932334B1 (ja) * 2005-12-13 2007-06-20 国立大学法人 北海道大学 クリーンユニットの運転方法
WO2008101127A2 (en) * 2007-02-15 2008-08-21 Broadley-James Corporation Bioreactor jacket
DE102010003043A1 (de) * 2010-03-19 2011-09-22 Robert Bosch Gmbh Prüfkammer
CN116040098B (zh) * 2022-12-30 2023-09-01 吉林省医疗器械检验研究院(吉林省医药医疗器械洁净环境监测中心、吉林省医疗器械质量认证中心) 一种密封性好的药品检验采样器

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3874754A (en) * 1972-11-27 1975-04-01 Kewaunee Scient Equipment Corp Biohazard safety cabinet
GB1396883A (en) * 1971-04-27 1975-06-11 Hepaire Filtration Ltd Work cabinets
EP0195703A1 (fr) * 1985-03-08 1986-09-24 Societe Nouvelle D'exploitation De La Calhene Installation pour travaux hors poussière, notamment pour la fabrication et le contrôle de composants électroniques,et son procédé de mise en oeuvre
WO1990005549A1 (en) * 1988-11-16 1990-05-31 Envair (Uk) Limited Clean air cabinets
WO1995034078A1 (en) * 1994-06-03 1995-12-14 Smithkline Beecham Biologicals S.A. Transferring articles between controlled environments
DE29622079U1 (de) * 1996-12-19 1997-07-03 Ludwig Joachim Flexible Module zum Lagern und Transportieren von empfindlichen Produkten unter Reinraumbedingungen
US5792427A (en) * 1996-02-09 1998-08-11 Forma Scientific, Inc. Controlled atmosphere incubator

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5411641B1 (ja) 1971-02-23 1979-05-16
JPS57127790A (en) * 1981-01-30 1982-08-09 Toshiba Corp Refrigerating device for closed box
DE4008838C1 (ja) * 1990-03-20 1991-05-16 Rittal-Werk Rudolf Loh Gmbh & Co Kg, 6348 Herborn, De
DE29716682U1 (de) * 1997-09-17 1997-11-06 Pfannenberg Otto Gmbh Vorrichtung zum Austausch von Wärmeenergie zwischen einem Gehäuseinnenraum und einer Umgebung
US6067233A (en) * 1998-02-27 2000-05-23 3Com Corporation Mounting brace and cable management apparatus and method
US6164369A (en) * 1999-07-13 2000-12-26 Lucent Technologies Inc. Door mounted heat exchanger for outdoor equipment enclosure

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1396883A (en) * 1971-04-27 1975-06-11 Hepaire Filtration Ltd Work cabinets
US3874754A (en) * 1972-11-27 1975-04-01 Kewaunee Scient Equipment Corp Biohazard safety cabinet
EP0195703A1 (fr) * 1985-03-08 1986-09-24 Societe Nouvelle D'exploitation De La Calhene Installation pour travaux hors poussière, notamment pour la fabrication et le contrôle de composants électroniques,et son procédé de mise en oeuvre
WO1990005549A1 (en) * 1988-11-16 1990-05-31 Envair (Uk) Limited Clean air cabinets
WO1995034078A1 (en) * 1994-06-03 1995-12-14 Smithkline Beecham Biologicals S.A. Transferring articles between controlled environments
US5792427A (en) * 1996-02-09 1998-08-11 Forma Scientific, Inc. Controlled atmosphere incubator
DE29622079U1 (de) * 1996-12-19 1997-07-03 Ludwig Joachim Flexible Module zum Lagern und Transportieren von empfindlichen Produkten unter Reinraumbedingungen

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010004279A2 (en) * 2008-07-08 2010-01-14 Ruskinn Life Sciences Limited Laboratory apparatus for a controlled environment
WO2010004279A3 (en) * 2008-07-08 2010-11-18 Ruskinn Life Sciences Limited Laboratory apparatus for a controlled environment

Also Published As

Publication number Publication date
JP2001074285A (ja) 2001-03-23
FR2795977A1 (fr) 2001-01-12
US6446716B1 (en) 2002-09-10
FR2795977B1 (fr) 2002-05-17

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