EP1023057A1 - Utilisation de thiazolidinediones pour le traitement de l'hyperglycemie - Google Patents

Utilisation de thiazolidinediones pour le traitement de l'hyperglycemie

Info

Publication number
EP1023057A1
EP1023057A1 EP98949088A EP98949088A EP1023057A1 EP 1023057 A1 EP1023057 A1 EP 1023057A1 EP 98949088 A EP98949088 A EP 98949088A EP 98949088 A EP98949088 A EP 98949088A EP 1023057 A1 EP1023057 A1 EP 1023057A1
Authority
EP
European Patent Office
Prior art keywords
hyperglycaemia
glucose levels
plasma glucose
insulin sensitiser
range
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98949088A
Other languages
German (de)
English (en)
Inventor
Robin Edwin SmithKline Beecham Pharm. BUCKINGHAM
Stephen Alistair SmithKline Beecham Pharm. Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of EP1023057A1 publication Critical patent/EP1023057A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Abstract

Procédé de traitement de l'hyperglycémie pour laquelle le taux plasmique de glucose se situe entre ⊃126 mg/dl et 140 mg/dl. Ledit procédé consiste à administrer à un mammifère qui le nécessite une quantité efficace, non toxique et acceptable sur le plan pharmaceutique d'un sensibilisant à l'insuline.
EP98949088A 1997-10-13 1998-10-12 Utilisation de thiazolidinediones pour le traitement de l'hyperglycemie Withdrawn EP1023057A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9721692.3A GB9721692D0 (en) 1997-10-13 1997-10-13 Novel treatment
GB9721692 1997-10-13
PCT/GB1998/003067 WO1999018944A1 (fr) 1997-10-13 1998-10-12 Utilisation de thiazolidinediones pour le traitement de l'hyperglycemie

Publications (1)

Publication Number Publication Date
EP1023057A1 true EP1023057A1 (fr) 2000-08-02

Family

ID=10820481

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98949088A Withdrawn EP1023057A1 (fr) 1997-10-13 1998-10-12 Utilisation de thiazolidinediones pour le traitement de l'hyperglycemie

Country Status (24)

Country Link
EP (1) EP1023057A1 (fr)
JP (1) JP2001519383A (fr)
KR (1) KR20010024482A (fr)
CN (1) CN1281358A (fr)
AP (1) AP1223A (fr)
AU (1) AU9547198A (fr)
BG (1) BG104405A (fr)
BR (1) BR9815220A (fr)
CA (1) CA2305289A1 (fr)
CZ (1) CZ20001298A3 (fr)
EA (1) EA200000418A1 (fr)
GB (1) GB9721692D0 (fr)
HR (1) HRP20000256A2 (fr)
HU (1) HUP0003673A3 (fr)
ID (1) ID24439A (fr)
IL (1) IL135515A0 (fr)
NO (1) NO20001897L (fr)
OA (1) OA11519A (fr)
PL (1) PL339804A1 (fr)
SK (1) SK5322000A3 (fr)
TR (1) TR200000957T2 (fr)
UA (1) UA66809C2 (fr)
WO (1) WO1999018944A1 (fr)
YU (1) YU28700A (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR200100207T2 (tr) * 1998-07-21 2001-05-21 Smithkline Beecham P.L.C. Apoptozun redüksiyonu için glükoz alımını kuvvetlendirici maddenin kullanıması

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0842925A1 (fr) * 1987-09-04 1998-05-20 Beecham Group Plc Thiazolidinédiones substituées
GB9218830D0 (en) * 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds
US5478852C1 (en) * 1993-09-15 2001-03-13 Sankyo Co Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of impaired glucose tolerance in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO9918944A1 *

Also Published As

Publication number Publication date
OA11519A (en) 2004-02-09
NO20001897L (no) 2000-06-09
WO1999018944A1 (fr) 1999-04-22
PL339804A1 (en) 2001-01-02
HRP20000256A2 (en) 2000-12-31
EA200000418A1 (ru) 2000-10-30
YU28700A (sh) 2003-10-31
AP1223A (en) 2003-11-13
CA2305289A1 (fr) 1999-04-22
UA66809C2 (uk) 2004-06-15
JP2001519383A (ja) 2001-10-23
GB9721692D0 (en) 1997-12-10
TR200000957T2 (tr) 2000-08-21
KR20010024482A (ko) 2001-03-26
IL135515A0 (en) 2001-05-20
CN1281358A (zh) 2001-01-24
AU9547198A (en) 1999-05-03
HUP0003673A3 (en) 2001-12-28
AP2000001788A0 (en) 2000-06-30
CZ20001298A3 (cs) 2001-08-15
ID24439A (id) 2000-07-20
BG104405A (en) 2000-12-29
SK5322000A3 (en) 2000-09-12
NO20001897D0 (no) 2000-04-12
HUP0003673A2 (hu) 2001-10-28
BR9815220A (pt) 2000-11-14

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