TR200100207T2 - Apoptozun redüksiyonu için glükoz alımını kuvvetlendirici maddenin kullanıması - Google Patents

Apoptozun redüksiyonu için glükoz alımını kuvvetlendirici maddenin kullanıması

Info

Publication number
TR200100207T2
TR200100207T2 TR2001/00207T TR200100207T TR200100207T2 TR 200100207 T2 TR200100207 T2 TR 200100207T2 TR 2001/00207 T TR2001/00207 T TR 2001/00207T TR 200100207 T TR200100207 T TR 200100207T TR 200100207 T2 TR200100207 T2 TR 200100207T2
Authority
TR
Turkey
Prior art keywords
apoptosis
glucose uptake
reduction
human
enhancing glucose
Prior art date
Application number
TR2001/00207T
Other languages
English (en)
Inventor
Michel Alain Bril Antoine
Edwin Buckingham Robin
Khandoudi Nassirah
Original Assignee
Smithkline Beecham P.L.C.
Smithkline Beecham Laboratoires Pharmacetiques S.A.S.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9815871.0A external-priority patent/GB9815871D0/en
Priority claimed from GBGB9815872.8A external-priority patent/GB9815872D0/en
Priority claimed from GBGB9905387.8A external-priority patent/GB9905387D0/en
Application filed by Smithkline Beecham P.L.C., Smithkline Beecham Laboratoires Pharmacetiques S.A.S. filed Critical Smithkline Beecham P.L.C.
Publication of TR200100207T2 publication Critical patent/TR200100207T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

Buna ihtiyaç duyan bir insana veya insan olmayan bir memeliye, bir glukoz alimini kuvvetlendirici maddesinin etkin, toksik olmayan bir miktarinin akut uygulamasi da dahil olmak üzere uygulanmasini kapsayan, insanda veya insan olmayan bir memelide kardiak miyositler, pankreatik beta hücreleri,endotelyal hücreler ve nöronal hücrelerden olusan listeden seçilmis diferansiye hücrelerin apoptozunun önlenmesi veya hafifletilmesi için bir metod.
TR2001/00207T 1998-07-21 1999-07-21 Apoptozun redüksiyonu için glükoz alımını kuvvetlendirici maddenin kullanıması TR200100207T2 (tr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9815871.0A GB9815871D0 (en) 1998-07-21 1998-07-21 Novel compound
GBGB9815872.8A GB9815872D0 (en) 1998-07-21 1998-07-21 Novel method
GBGB9905387.8A GB9905387D0 (en) 1999-03-09 1999-03-09 Novel method

Publications (1)

Publication Number Publication Date
TR200100207T2 true TR200100207T2 (tr) 2001-05-21

Family

ID=27269407

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/00207T TR200100207T2 (tr) 1998-07-21 1999-07-21 Apoptozun redüksiyonu için glükoz alımını kuvvetlendirici maddenin kullanıması

Country Status (26)

Country Link
EP (2) EP1098639B1 (tr)
JP (1) JP2002521326A (tr)
KR (1) KR20010079551A (tr)
CN (1) CN1310620A (tr)
AP (1) AP2001002036A0 (tr)
AT (1) ATE288746T1 (tr)
AU (1) AU5053799A (tr)
BG (1) BG105250A (tr)
BR (1) BR9912117A (tr)
CA (1) CA2338211A1 (tr)
DE (1) DE69923687T2 (tr)
DK (1) DK1098639T3 (tr)
EA (1) EA200100165A1 (tr)
ES (1) ES2237929T3 (tr)
HK (1) HK1037865A1 (tr)
HU (1) HUP0103199A3 (tr)
ID (1) ID26986A (tr)
IL (1) IL140664A0 (tr)
NO (1) NO20010292L (tr)
OA (1) OA11579A (tr)
PL (1) PL345627A1 (tr)
PT (1) PT1098639E (tr)
SI (1) SI1098639T1 (tr)
SK (1) SK1012001A3 (tr)
TR (1) TR200100207T2 (tr)
WO (1) WO2000004890A1 (tr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000043007A1 (fr) * 1999-01-19 2000-07-27 Sankyo Company, Limited Compositions médicinales à base de troglitazone inhibitrices de l'apoptose
AU7073400A (en) * 1999-08-27 2001-03-26 Eli Lilly And Company Biaryl-oxa(thia)zole derivatives and their use as ppars modulators

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3856378T2 (de) * 1987-09-04 2000-05-11 Beecham Group Plc Substituierte Thiazolidindionderivate
JPH05202042A (ja) * 1992-01-24 1993-08-10 Sankyo Co Ltd 糖尿病性合併症治療剤
GB9218830D0 (en) * 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds
NZ314406A (en) * 1996-03-18 2000-12-22 Sankyo Co Treatment or prophylaxis of pancreatitis with a medicament containing an insulin sensitiser including oxazoles and thiazoles
GB9611947D0 (en) * 1996-06-07 1996-08-07 Glaxo Group Ltd Medicaments
US6277819B1 (en) * 1996-08-30 2001-08-21 Eli Lilly And Company Use of GLP-1 or analogs in treatment of myocardial infarction
NZ334577A (en) * 1996-09-12 2001-03-30 Sankyo Co Glutathione reductase activity potentiator containing troglitazone
GB9721692D0 (en) * 1997-10-13 1997-12-10 Smithkline Beecham Plc Novel treatment
EP1047423B1 (en) * 1997-11-19 2006-05-10 Takeda Pharmaceutical Company Limited Novel apoptosis inhibitors
AU2781899A (en) * 1998-02-24 1999-09-15 Trustees Of The University Of Pennsylvania, The Use of a cardiac purinoceptor to effect cellular glucose uptake
WO1999059586A1 (en) * 1998-05-19 1999-11-25 Regents Of The University Of California Thiazolidine and oxazolidine derivatives for the treatment of acute myocardial infarction and inhibition of cardiomyocyte apoptosis
US5968960A (en) * 1999-01-14 1999-10-19 The Regents Of The University Of California Use of thiazolidinediones to ameliorate the adverse consequences of myocardial ischemia on myocardial function and metabolism

Also Published As

Publication number Publication date
DE69923687T2 (de) 2006-04-06
AU5053799A (en) 2000-02-14
PT1098639E (pt) 2005-06-30
NO20010292L (no) 2001-03-08
ES2237929T3 (es) 2005-08-01
WO2000004890A1 (en) 2000-02-03
DK1098639T3 (da) 2005-06-13
SK1012001A3 (en) 2001-08-06
OA11579A (en) 2004-06-01
BG105250A (en) 2001-11-30
NO20010292D0 (no) 2001-01-18
EP1516617A2 (en) 2005-03-23
HUP0103199A3 (en) 2002-08-28
AP2001002036A0 (en) 2001-03-31
ATE288746T1 (de) 2005-02-15
DE69923687D1 (de) 2005-03-17
IL140664A0 (en) 2002-02-10
HUP0103199A2 (hu) 2002-05-29
CA2338211A1 (en) 2000-02-03
HK1037865A1 (en) 2002-02-22
PL345627A1 (en) 2002-01-02
SI1098639T1 (tr) 2005-08-31
CN1310620A (zh) 2001-08-29
KR20010079551A (ko) 2001-08-22
ID26986A (id) 2001-02-22
EA200100165A1 (ru) 2001-08-27
EP1098639B1 (en) 2005-02-09
EP1098639A1 (en) 2001-05-16
JP2002521326A (ja) 2002-07-16
BR9912117A (pt) 2001-04-10

Similar Documents

Publication Publication Date Title
BR9914789A (pt) Derivados de ácido lipóico e seus usos no tratamento de doença
ES2144039T3 (es) Procedimiento y dispositivo para el abombado de hojas de vidrio.
ZA992005B (en) Proton donating actives in absorbent articles.
IL144703A0 (en) Methods and reagents for treating glucose metabolic disorders
DE69927288D1 (de) Adsorbent-Zusammensetzung und deren Verwendung zur Bindung von Hautirritierenden Mittel.
TR199902608T2 (tr) Bogaz yumusatici bilesimler.
CY1111516T1 (el) Μακροκυκλικα αναλογα και μεθοδοι χρησης και παρασκευης τους
NZ516349A (en) Conjugates of phytosterol or phytostanol with ascorbic acid and use thereof in treating or preventing cardiovascular disease
MXPA00007388A (es) Metodos para tratar la pigmentacion de la piel.
TR199701365T1 (tr) Bir külot bileseni ve bir emici pedi haiz hijyenik külot.
IL187254A (en) ANTISENSE NUCLEOTIDES, COMPOSITIONS COMPRISING THEREOF AND THEIR USE IN MODULATING ACTIVATION OF NF-kB
IL143569A0 (en) A combination of fbpase inhibitors and insulin sensitizers for the treatment of diabetes
ITBO930075A1 (it) Tramoggia per elementi allungati, in particolare articoli da fumo.
TR200102605T2 (tr) Monoterpen ketonları katkısı ihtiva eden nikotin içerikli TTS sistemleri (transdermaltedavi amaçlı sistemler)
AU2003216517A8 (en) Iliac bifurcation balloon catheter
TR200100207T2 (tr) Apoptozun redüksiyonu için glükoz alımını kuvvetlendirici maddenin kullanıması
AR004494A1 (es) Una celula util para el tratamiento del dolor, un metodo para producirla, un organo bioartificial de la comprende y un metodo para preparar dicho organobioartificial
TR200101766T2 (tr) Dehidroepiandrosteronun klatratları ve bunlara tekabül eden kompozisyonlar
MY134896A (en) Therapeutic agent for hepatitis
NZ329839A (en) Combination of a compound which inhibits acetylcholinesterase or exhibits muscarinergic action and a compound which increases the endogenous extracellular adenosine level for treating dementia
ATE203674T1 (de) Verwendung eines extraktes von alchemilla vulgaris
AR020614A1 (es) Nuevo metodo
ECSP993063A (es) Nuevo metodo para reducir o prevenir la apoptosis de celulas diferenciadas
WO2001051093A3 (en) METHODS OF INCREASING THE GLUCOSE RESPONSIVENESS OF PANCREATIC β-CELLS
ES287265U (es) Expositor para cinturones de vestir