EP0919215A1 - Glasampulle zur Aufnahme einer Flüssigkeit - Google Patents
Glasampulle zur Aufnahme einer Flüssigkeit Download PDFInfo
- Publication number
- EP0919215A1 EP0919215A1 EP97890231A EP97890231A EP0919215A1 EP 0919215 A1 EP0919215 A1 EP 0919215A1 EP 97890231 A EP97890231 A EP 97890231A EP 97890231 A EP97890231 A EP 97890231A EP 0919215 A1 EP0919215 A1 EP 0919215A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- glass ampoule
- area
- coating
- ampoule
- region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/06—Ampoules or carpules
- A61J1/065—Rigid ampoules, e.g. glass ampoules
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
Definitions
- the invention relates to a glass ampoule for holding a liquid, for example one Drug, a calibration or quality control liquid, with an essentially flat floor or with a floor area drawn in to the inside of the ampoule.
- a liquid for example one Drug, a calibration or quality control liquid
- Such ampoules are used in large numbers, especially in medical laboratories and in Medical practices and clinics are used, the glass ampoules being used to remove their contents usually have to be broken open by hand and brought to their destination.
- EP 0 694 498 B1 describes an automatic device Removal of a liquid from a sealed glass ampoule, in which the glass ampoule in an upright position, the bottom of the ampoule pointing upwards is held in a holder.
- the bottom of the glass ampoule is covered by a rigid, single-lumen cannula mechanically destroyed, this cannula simultaneously for suction serves the liquid from a splinter-free area of the glass ampoule.
- the object of the invention is to provide known glass ampoules for holding liquids in this way to further develop a problem-free opening through the floor area by automatically working removal devices is guaranteed.
- the floor area through its Forming and / or a coating has a defined predetermined breaking area, which can be mechanically destroyed with little effort.
- the bottom area has an asymmetrical, conical depression having.
- asymmetrical, conical depressions can, for example, with a blower are manufactured during the manufacturing process, wall parts of the The ampoule base is blown into the interior of the ampoule in a reproducible form and depth become. There are bulges of approximately half the diameter of the ampoule proven to be advantageous. To strengthen the wall area, this can be done during blowing specifically cooled and the optimal arching of an automatic optical control be subjected.
- the reduced rigidity of the floor area due to the asymmetry allows es, a withdrawal cannula with much less effort in the glass ampoule introduce, the splintering essentially on the asymmetrically shaped Area remains limited.
- the retracted bottom area is a compared to the wall thickness of the glass ampoule reduced, preferably 30 to 60% reduced wall thickness.
- the wall thickness of the glass ampoule reduced, preferably 30 to 60% reduced wall thickness.
- a Coating can be provided from a material which tension forces between the coated floor area and the coating.
- This, for example, ceramic Coating can also be in a punctiform formation on the center of the limit the retracted area or the point of attack of a removal element.
- the floor preferably has a ceramic coating in its central area, and possibly also the bottom of the glass ampoule, especially in its central one Area, a reduced compared to the wall thickness of the glass ampoule, preferably around 30 to 60% reduced wall thickness.
- the glass ampoule 1 shown in FIG. 1a for holding a liquid has one on the inside of the ampoule retracted bottom area 2.
- the cylindrical shaft portion 3 of the Ampoule 1 merges into a neck area 4 and this into a head area 5.
- the areas 3 up to 4 can essentially be of any design, it only has to be guaranteed that the ampoule in a device for automatic withdrawal of ampoule liquid - like this is known for example from EP 0 694 498 B1 - can be used.
- the base region 2 of the ampoule according to FIG. 1a has a conical depression, which a punctiform ceramic coating 7 in the center of the drawn-in area 2 has (see also Fig. 1b).
- FIGS. 2a and 2b has an asymmetrical, conical shape in the bottom area 2 Indentation 6 'with reduced wall thickness, whereby a center in the direction of Removal element 12 engaging axis 1 'of the ampoule has a reduced mechanical There is resistance when opening the floor.
- Fig. 2b here is also the ceramic coating 7 asymmetrical, namely at the lowest point of the conical Well 6 'arranged.
- the bottom region 2 of the ampoule 1 is in the essentially cylindrical recess 8 executed, which is a flat or slightly curved Floor 9 has.
- the wall thickness of the retracted floor area 2 can Whole or only in a central area compared to the wall thickness of the Glass ampoule 1 have reduced wall thickness.
- a glass ampoule 1 which has a substantially flat bottom 10, this entirely or in its central area for easier penetration of the removal element a reduced wall thickness (30 - 60%).
- Such bases can, for example, on the shaft of the ampoule welded or melted.
- a ceramic coating 7 in the form of a ceramic point can be applied. It it is also possible for the bottom area or the bottom 10 of the glass ampoule 1 to be scored, preferably has a circular scoring 12.
- an elastomer coating indicated in FIG. 4a can be used in all design variants 11 can be provided, which on a to the floor 10 (or floor area 2) Glass ampoule 1 adjoining cylindrical shaft region 3 is applied. This elastomer coating is used to hold any splinters in the lower shaft area.
Landscapes
- Health & Medical Sciences (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Details Of Rigid Or Semi-Rigid Containers (AREA)
Abstract
Description
Claims (9)
- Glasampulle (1) zur Aufnahme einer Flüssigkeit, vorzugsweise eines Arzneimittels, einer Kalibrier- oder einer Qualitätskontrollflüssigkeit, mit einem zur Innenseite der Ampulle eingezogenen Bodenbereich (2), dadurch gekennzeichnet, daß der Bodenbereich (2) durch seine Formgebung (6', 8, 4) und/oder eine Beschichtung (7) einen definierten Sollbruchbereich aufweist, welcher mit geringem Kraftaufwand mechanisch zerstörbar ist.
- Glasampulle nach Anspruch 1, dadurch gekennzeichnet, daß der Bodenbereich (2) eine asymmethische, konische Vertiefung (6') aufweist.
- Glasampulle nach Anspruch 1, dadurch gekennzeichnet, daß der Bodenbereich (2) eine im wesentlichen zylindrische Vertiefung (8) mit einem ebenen oder leicht gewölbten Boden (9) aufweist.
- Glasampulle nach einem der Ansprüche 1 bis 3, dadurch gekennzeichnet, daß der eingezogene Bodenbereich (2) eine im Vergleich zur Wandstärke der Glasampulle (1) verminderte, vorzugsweise um 30 bis 60% verringerte Wandstärke aufweist.
- Glasampulle nach einem der Ansprüche 1 bis 4, dadurch gekennzeichnet, daß der Bodenbereich (2), vorzugsweise das Zentrum des eingezogenen Bereiches eine Beschichtung (7) aus einem Material, beispielsweise Keramik, aufweist, welches Spannungskräfte zwischen dem beschichteten Bodenbereich (2) und der Beschichtung (7) hervorruft.
- Glasampulle (1) zur Aufnahme einer Flüssigkeit, beispielsweise eines Arzneimittels, einer Kalibrier- oder einer Qualitätskontrollflüssigkeit, mit einem im wesentlichen ebenen Boden (10), dadurch gekennzeichnet, daß der Boden (10) in seinem zentralen Bereich, eine Beschichtung (7) aus einem Material, beispielsweise Keramik, aufweist, welches Spannungskräfte zwischen dem Boden (10) und der Beschichtung (7) hervorruft.
- Glasampulle nach Anspruch 6, dadurch gekennzeichnet, daß der Boden (10) der Glasampulle, insbesondere in seinem zentralen Bereich, eine im Vergleich zur Wandstärke der Glasampulle verminderte, vorzugsweise um 30 bis 60% verringerte, Wandstärke aufweist.
- Glasampulle nach einem der Ansprüche 1 oder 6, dadurch gekennzeichnet, daß der Bodenbereich (2) bzw. der Boden (10) der Glasampulle (1) eine Anritzung, vorzugsweise eine kreisförmige Anritzung (12) aufweist.
- Glasampulle nach einem der Ansprüche 1 bis 8, dadurch gekennzeichnet, daß der an den Bodenbereich (2) bzw. Boden (10) der Glasampulle (1) anschließende zylindrische Schaftbereich (3) eine Elastomerbeschichtung (11) aufweist.
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97890231A EP0919215B1 (de) | 1997-11-24 | 1997-11-24 | Glasampulle zur Aufnahme einer Flüssigkeit |
DE59706326T DE59706326D1 (de) | 1997-11-24 | 1997-11-24 | Glasampulle zur Aufnahme einer Flüssigkeit |
US09/000,948 US5948366A (en) | 1997-11-24 | 1997-12-30 | Glass ampoule for holding a drug a calibration liquid or a quality control liquid |
JP10332133A JP3062687B2 (ja) | 1997-11-24 | 1998-11-24 | 薬剤、較正用液又は品質管理用液用ガラス製アンプル |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97890231A EP0919215B1 (de) | 1997-11-24 | 1997-11-24 | Glasampulle zur Aufnahme einer Flüssigkeit |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0919215A1 true EP0919215A1 (de) | 1999-06-02 |
EP0919215B1 EP0919215B1 (de) | 2002-02-06 |
Family
ID=8231126
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP97890231A Expired - Lifetime EP0919215B1 (de) | 1997-11-24 | 1997-11-24 | Glasampulle zur Aufnahme einer Flüssigkeit |
Country Status (4)
Country | Link |
---|---|
US (1) | US5948366A (de) |
EP (1) | EP0919215B1 (de) |
JP (1) | JP3062687B2 (de) |
DE (1) | DE59706326D1 (de) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102011112516A1 (de) * | 2011-09-07 | 2013-03-07 | Aap Biomaterials Gmbh | Flüssigkeitsbehälter mit Sollbruchstelle |
US9186635B2 (en) | 2009-03-17 | 2015-11-17 | Stryker Ireland Limited | Vacuum mixing device for bone cement and method for mixing bone cement in said device |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6340097B1 (en) | 1998-10-22 | 2002-01-22 | Closure Medical Corporation | Applicator with protective barrier |
US20060042373A1 (en) * | 2004-08-25 | 2006-03-02 | Kirollos Kirollos S | Smoke generating device |
CA2578724A1 (en) * | 2004-09-08 | 2006-03-16 | The Dial Corporation | Methods and apparatus for a low-cost vapor-dispersing device |
US8911691B2 (en) | 2008-06-06 | 2014-12-16 | Capitol Plastic Products, Llc | Rack with vial |
EP3647781B1 (de) | 2018-10-29 | 2024-05-01 | EXIAS Medical GmbH | Messkartusche zur messung einer flüssigkeitsprobe |
CN116744819A (zh) | 2021-01-20 | 2023-09-12 | 莱雅公司 | 玻璃注射器滴管 |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB191501531A (en) * | 1914-12-02 | 1915-12-30 | Wilfred Ambrose Whatmough | Improved Construction of Ampoule or the like with Means for Applying the Contents to the Body. |
GB198993A (en) * | 1922-06-06 | 1924-08-13 | Friedrich Wilhelm Horst | Improvements in flasks for containing chemicals, and in means for opening the same and discharging their contents |
FR721646A (fr) | 1930-11-14 | 1932-03-05 | Negoce Et Ind | Ampoule destinée à contenir de l'anhydride sulfureux ou tout autre gaz liquéfié sous pression. et appareil pour briser cette ampoule et diffuser le gaz qu'elle contient dans un liquide quelconque |
US1951743A (en) * | 1930-04-25 | 1934-03-20 | Iso Ges M B H | Method of producing a prepared breaking point in ampulle |
CH287394A (fr) * | 1950-07-07 | 1952-11-30 | Owens Illinois Glass Co | Récipient en verre et procédé pour sa fabrication. |
FR1241230A (fr) * | 1959-08-04 | 1960-09-16 | Prolabo Sa | Ampoule pour le conditionnement de réactifs |
US3535070A (en) * | 1966-02-03 | 1970-10-20 | Owens Illinois Inc | Method of inducing stress in glass containers and container made with a stressed zone |
EP0694498A1 (de) | 1994-07-28 | 1996-01-31 | AVL Medical Instruments AG | Verfahren und Vorrichtung zur Entnahme einer Flüssigkeit aus einer verschlossenen Glasampulle |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3749271A (en) * | 1971-06-22 | 1973-07-31 | Becton Dickinson Co | Resealable ampoule closure |
FR2237643B1 (de) * | 1973-07-17 | 1978-03-17 | Steiner Maurice | |
SU607138A1 (ru) * | 1975-10-27 | 1978-05-15 | Предприятие П/Я Г-4236 | Ампула дл инжектировани в хроматограф продуктов реакции |
US4096683A (en) * | 1977-02-16 | 1978-06-27 | Cozzoli Machine Company | Ampoule filling and sealing machine |
US4266681A (en) * | 1977-02-28 | 1981-05-12 | Oceanography International Corporation | Multiple breakpoint resealable ampoule |
IL60740A (en) * | 1980-08-01 | 1983-06-15 | Tadiran Israel Elect Ind Ltd | Electrolyte container for use in reserve cells |
ES8504055A1 (es) * | 1983-03-10 | 1985-04-16 | Dehais Claude | Perfeccionamientos en las maquinas para elaborar ampollas farmaceuticas y similares y anpolla obtenida. |
SE8505542L (sv) * | 1985-11-25 | 1987-05-26 | Vestsvensk Medicinteknik Ab | Anordning for brytning av ampuller |
US5179024A (en) * | 1991-05-30 | 1993-01-12 | Harald Dahms | Sealed vials containing improved karl fischer solutions, and process for water determination using these vials |
US5221311A (en) * | 1992-01-10 | 1993-06-22 | Rising Peter E | Evacuated sampling vial |
-
1997
- 1997-11-24 EP EP97890231A patent/EP0919215B1/de not_active Expired - Lifetime
- 1997-11-24 DE DE59706326T patent/DE59706326D1/de not_active Expired - Lifetime
- 1997-12-30 US US09/000,948 patent/US5948366A/en not_active Expired - Lifetime
-
1998
- 1998-11-24 JP JP10332133A patent/JP3062687B2/ja not_active Expired - Fee Related
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB191501531A (en) * | 1914-12-02 | 1915-12-30 | Wilfred Ambrose Whatmough | Improved Construction of Ampoule or the like with Means for Applying the Contents to the Body. |
GB198993A (en) * | 1922-06-06 | 1924-08-13 | Friedrich Wilhelm Horst | Improvements in flasks for containing chemicals, and in means for opening the same and discharging their contents |
US1951743A (en) * | 1930-04-25 | 1934-03-20 | Iso Ges M B H | Method of producing a prepared breaking point in ampulle |
FR721646A (fr) | 1930-11-14 | 1932-03-05 | Negoce Et Ind | Ampoule destinée à contenir de l'anhydride sulfureux ou tout autre gaz liquéfié sous pression. et appareil pour briser cette ampoule et diffuser le gaz qu'elle contient dans un liquide quelconque |
CH287394A (fr) * | 1950-07-07 | 1952-11-30 | Owens Illinois Glass Co | Récipient en verre et procédé pour sa fabrication. |
FR1241230A (fr) * | 1959-08-04 | 1960-09-16 | Prolabo Sa | Ampoule pour le conditionnement de réactifs |
US3535070A (en) * | 1966-02-03 | 1970-10-20 | Owens Illinois Inc | Method of inducing stress in glass containers and container made with a stressed zone |
EP0694498A1 (de) | 1994-07-28 | 1996-01-31 | AVL Medical Instruments AG | Verfahren und Vorrichtung zur Entnahme einer Flüssigkeit aus einer verschlossenen Glasampulle |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9186635B2 (en) | 2009-03-17 | 2015-11-17 | Stryker Ireland Limited | Vacuum mixing device for bone cement and method for mixing bone cement in said device |
US9999459B2 (en) | 2009-03-17 | 2018-06-19 | Stryker European Holdings I, Llc | Vacuum mixing device for bone cement and method for mixing bone cement in said device |
DE102011112516A1 (de) * | 2011-09-07 | 2013-03-07 | Aap Biomaterials Gmbh | Flüssigkeitsbehälter mit Sollbruchstelle |
WO2013034302A2 (de) | 2011-09-07 | 2013-03-14 | Aap Biomaterials Gmbh | Flüssigkeitsbehälter mit sollbruchstelle |
US9642774B2 (en) | 2011-09-07 | 2017-05-09 | Stryker European Holdings I, Llc | Liquid container with predetermined breaking point |
DE102011112516B4 (de) | 2011-09-07 | 2024-02-29 | Stryker European Operations Holdings Llc | Gebinde mit einem Behälter zur Aufnahme einer Flüssigkeit und einer Flüssigkeitsentnahmeeinrichtung |
Also Published As
Publication number | Publication date |
---|---|
EP0919215B1 (de) | 2002-02-06 |
JP3062687B2 (ja) | 2000-07-12 |
JPH11221266A (ja) | 1999-08-17 |
DE59706326D1 (de) | 2002-03-21 |
US5948366A (en) | 1999-09-07 |
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