EP0813472B1 - Device for producing tablets - Google Patents

Device for producing tablets Download PDF

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Publication number
EP0813472B1
EP0813472B1 EP96943935A EP96943935A EP0813472B1 EP 0813472 B1 EP0813472 B1 EP 0813472B1 EP 96943935 A EP96943935 A EP 96943935A EP 96943935 A EP96943935 A EP 96943935A EP 0813472 B1 EP0813472 B1 EP 0813472B1
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EP
European Patent Office
Prior art keywords
rotor
pressing tools
filling
pressure
exerting
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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EP96943935A
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German (de)
French (fr)
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EP0813472A1 (en
Inventor
Rudolf Koch
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GEA Process Engineering NV
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Courtoy NV
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/025—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space whereby the material is transferred into the press chamber by relative movement between a ram and the press chamber
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/08—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/12—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds on the circumference of a rotating drum
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
    • B30B15/30—Feeding material to presses
    • B30B15/302—Feeding material in particulate or plastic state to moulding presses
    • B30B15/308—Feeding material in particulate or plastic state to moulding presses in a continuous manner, e.g. for roller presses, screw extrusion presses

Definitions

  • the invention relates to a device for producing tablets or compacts according to the preamble of claim 1.
  • a pressing device for pressing coal briquettes with the subject Features of the preamble of claim 1 is already from US 1,448,982 known in 1923.
  • Such a briquette press is usually pulverized Coal pressed into briquettes together with a suitable binder.
  • a device for pressing feed is known from the press ram to form a compact by means of a controlled by setting discs Lever mechanism are movable.
  • Automatic devices for the production of tablets are based on the principle that a tablet is compressed into a tablet due to a pressing process.
  • two movable punches serve as pressing tools.
  • Known automatic Devices for producing tablets have a lower stamp aligned vertically, that runs in a die and an upper stamp that only goes into the die Pressing is introduced.
  • the upper punch slides into the die, pushes the powder together and squeezes the tablet. Thickness, strength depend on him and his pressure and press gloss of the tablet. Leave the insertion depth and pressure level regulate oneself.
  • the lower stamp is located inside the die. It limits the filling space down. During the pressing process, it usually forms the counter bearing.
  • the matrices are filled using a Filling funnel, the bottom part of which is called a filling shoe.
  • each die has an upper and a lower stamp.
  • the stamps are raised and lowered by rolling.
  • the dies are successively filled with their stamps Position brought under the filling shoe.
  • the object of the invention is therefore a device for producing tablets or tablets to hand, with the tablets or tablets without the so-called "Black spots" can be produced on the tablet surface.
  • the pressing tools which are movable relative to one another, are conventional Tablet machines no longer aligned vertically, but horizontally. By this measure can effectively prevent the occurrence of the "black spots" become.
  • the pressing tools are rotatable on one Rotor arranged.
  • a pressure roller is mounted eccentrically to the axis of rotation of the rotor and on the edge of the rotating part of the device are two further pressure rollers arranged so that over the eccentric pressure roller and the other two Pressure rollers the pressing tools arranged between them during the corresponding pass are pressed against each other.
  • the filling device can with be coupled to the rotor such that they rotate together with it is relocatable.
  • the rotor and the filling device can be connected to one another via the axis of rotation be coupled.
  • the filling device can consist of a bulbous shape
  • Filling hoppers exist, on which funnel-shaped tapered channels are attached are, the tapered ends of which open into a filling opening of the respective die. This arrangement of the hopper allows the dies to be centrifugally applied be filled with the tablets. This can also cause poorly flowing Materials are processed well and it can be dosed more precisely.
  • the mutually movable pressing tools are advantageous during their rotation moved in the horizontal direction by guide curves assigned to them. As a result, a correspondingly assigned one can be used for certain angular positions Work cycle to be carried out.
  • the two other pressure rollers can be at a different distance the associated pressing tools can be arranged that a different strength Press pressure can be generated. This allows through at a certain angular position a first pressure roller can be used to pre-press and at a second angular position complete pressing can be done by the second pressure roller.
  • the device shown in FIGS. 1 and 2 has one driven by a motor, not shown here Rotor 1, which rotates in the direction of rotation a according to FIG. 2 is relocatable. Aligned horizontally on this rotor in each case two pressing tools movably arranged relative to one another 2, 4 mounted.
  • the pressing tools 2, 4 are in the form of a inner stamp 4 and an outer stamp 2 formed, the Immerse in a corresponding hole in a die 3.
  • the circumference of the rotor 1 in the present exemplary embodiment four pairs of press tools with the corresponding dies interact, arranged.
  • a material hopper 5 is additionally arranged, which rotates together with the rotor 1.
  • the outer press tool 2 i.e. the outer stamp
  • the second press tool 4 i.e. the inner stamp
  • a guide curve 11 during the rotation of the rotor 1 shifted in the horizontal plane of the rotor.
  • the pressure rollers 6, 7 and 8 are adjustable.
  • the in middle region of the rotor 1 is arranged pressure roller 6 arranged eccentrically to the axis A of the rotor 1, wherein its eccentricity is adjustable.
  • the pressure rollers 7 and 8 are each adjustable in their distance from the rotor 1. Due to this adjustability, the pressing forces can form the tablet or the compact can be varied. Basically serve the pressure rollers 6, 7 and 8, as previously stated, to generate the necessary pressing forces and on the pressing tools transferred to. It comes with each passage of the pair of press tools 2, 4 between the respectively assigned pressure rollers 6 and 8 and 6 and 7 on the compression of the matrix content.
  • the filling device 5 is in the embodiment shown here designed as a bellied filling funnel, the funnel shape being formed by an inside of the hopper arranged cone is obtained. Between the hopper 5 and corresponding filling openings 10 in the matrices 3, funnel-shaped channels 9 are formed. Due to the centrifugal forces caused by the rotation of the Filling funnel on those located in the tapered ends Tablets particles act, is a safe promotion and thus filling the matrices 3 in position I guaranteed.
  • FIG. 3-5 are different working positions the pressing tools 2 and 4 shown to each other.
  • 3 the matrix filling phase is shown. This representation corresponds to position I in FIG. 2.
  • FIG. 4 the Compression of the tableted material shown. This corresponds to phase 2 positions II and III according to FIG. 2.
  • Phase III corresponds to position IV according to FIG. 2.
  • the finished tablet T by a corresponding Slit 13 downward due to gravity drop a collecting container, not shown here can.

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Formation And Processing Of Food Products (AREA)
  • Encapsulation Of And Coatings For Semiconductor Or Solid State Devices (AREA)
  • Control And Other Processes For Unpacking Of Materials (AREA)

Description

Die Erfindung betrifft eine Vorrichtung zur Herstellung von Tabletten oder Preßlingen nach dem Oberbegriff des Anspruchs 1.The invention relates to a device for producing tablets or compacts according to the preamble of claim 1.

Eine Preßvorrichtung zum Pressen von Kohlebriketts mit den gegenständlichen Merkmalen des Oberbegriffs des Anspruchs 1 ist bereits aus der US 1,448, 982 aus dem Jahr 1923 bekannt. In einer derartigen Brikettpresse wird üblicherweise pulverisierte Kohle zusammen mit einem geeigneten Bindemittel zu Briketts verpresst.A pressing device for pressing coal briquettes with the subject Features of the preamble of claim 1 is already from US 1,448,982 known in 1923. Such a briquette press is usually pulverized Coal pressed into briquettes together with a suitable binder.

Aus der FR 2 397 227 ist eine Vorrichtung zum Pressen von Futtermitteln bekannt, bei der Preßstempel zum Bilden eines Preßlings mittels eines über Kulissenscheiben gesteuerten Hebelmechanismus bewegbar sind.From FR 2 397 227 a device for pressing feed is known from the press ram to form a compact by means of a controlled by setting discs Lever mechanism are movable.

Automatische Vorrichtungen zur Herstellung von Tabletten basieren auf dem Prinzip, daß ein Tablettiergut aufgrund eines Preßvorganges zu einer Tablette verpresst wird. Hierzu dienen zwei bewegliche Stempel als Preßwerkzeuge. Bekannte automatische Vorrichtungen zur Herstellung von Tabletten besitzen vertikal ausgerichtet einen Unterstempel, der in einer Matrize läuft und einen Oberstempel, der in die Matrize nur zur Pressung eingeführt wird. Der Oberstempel gleitet in die Matrize, schiebt das Pulver zusammen und preßt die Tablette. Von ihm und seinem Preßdruck hängen Dicke, Festigkeit und Preßglanz der Tablette ab. Die Einführungstiefe und die Druckstärke lassen sich regulieren. Der Unterstempel befindet sich innerhalb der Matrize. Er begrenzt den Füllraum nach unten. Während des Preßvorgangs bildet er in der Regel das Gegenlager. Nach Abschluß der Pressung wird er nach oben geführt und bringt dadurch die Tablette auf den Matrizenrand, wo sie beiseite geschoben wird. Im nächsten Takt fällt der Unterstempel in seine Ausgangsstellung zurück und der Matrizenraum ist zur Aufnahme der nächsten Füllung bereit. Die Befüllung der Matrizen erfolgt über einen Fülltrichter, dessen unterster Teil Füllschuh genannt wird.Automatic devices for the production of tablets are based on the principle that a tablet is compressed into a tablet due to a pressing process. For this purpose, two movable punches serve as pressing tools. Known automatic Devices for producing tablets have a lower stamp aligned vertically, that runs in a die and an upper stamp that only goes into the die Pressing is introduced. The upper punch slides into the die, pushes the powder together and squeezes the tablet. Thickness, strength depend on him and his pressure and press gloss of the tablet. Leave the insertion depth and pressure level regulate oneself. The lower stamp is located inside the die. It limits the filling space down. During the pressing process, it usually forms the counter bearing. After completing the pressing, it is brought up and brings thereby the tablet on the edge of the die, where it is pushed aside. In the next bar the lower die falls back into its initial position and the die space is closed Ready for the next filling. The matrices are filled using a Filling funnel, the bottom part of which is called a filling shoe.

Diese bekannten Vorrichtungen werden heute in der Regel als Rundlauftablettenmaschinen ausgebildet. Bei diesen Typen steht der Füllschuh des Fülltrichters fest, während die Matrize beweglich ist. Eine runde Horizontalplatte trägt eine Anzahl von Matrizen. Zu jeder Matrize gehören, wie zuvor ausgeführt, ein Ober- und ein Unterstempel. Durch Rollen werden die Stempel jeweils gehoben und gesenkt. Durch Drehung einer horizontalen Platte werden die Matrizen mit ihren Stempeln nacheinander in füllbereite Stellung unter den Füllschuh gebracht.These known devices are usually used as rotary tablet machines today educated. In these types, the filling shoe of the hopper is fixed while the die is movable. A round horizontal plate carries a number of matrices. As previously stated, each die has an upper and a lower stamp. The stamps are raised and lowered by rolling. By rotation In a horizontal plate, the dies are successively filled with their stamps Position brought under the filling shoe.

Rundlauftablettenmaschinen weisen aus verfahrenstechnologischer Sicht einige gravierende Mängel auf, die aufgrund des zuvor geschilderten Konstruktionsprinzips der Vorrichtung nicht vollständig zu beseitigen sind. Dabei stehen bei der Herstellung von Tabletten zu pharmazeutischen Zwecken oder auch von Preßlingen im Lebensmittelbereich folgende Nachteile im Vordergrund:

  • Eine intensive Vorbehandlung der zu verpressenden Substanzen ist notwendig, um ein gutes Fließverhalten und damit die Dosierbarkeit zu erreichen.
  • Das Füllprinzip (fixierter Füllschuh auf rotierendem Matrizentisch) hat zur Folge, daß relativ hohe Materialverluste hingenommen werden müssen und durch die am Füllschuh vorzusehenden Dichtleisten, beispielsweise Metallabrieb ins zu fertigende Produkt gelangt. Es entstehen die sogenannten schwarzen Flecken auf der Tablettenoberfläche.
  • Im Preßraum der Vorrichtung entstehender Staub wird zunächst auf den freien Oberflächen der gefetteten Oberstempel abgelagert. Er fällt bei andauerndem Prozeß ab und gelangt über den Matrizentisch in den Füllschuh. Auch dieser Effekt führt zu den bereits zuvor genannten "schwarzen Flecken" auf der Tablettenoberfläche.
From a process technology point of view, rotary tablet machines have some serious shortcomings that cannot be completely remedied due to the above-described design principle of the device. The main drawbacks in the manufacture of tablets for pharmaceutical purposes or pressed tablets in the food sector are:
  • Intensive pretreatment of the substances to be pressed is necessary in order to achieve good flow behavior and thus meterability.
  • The filling principle (fixed filling shoe on rotating die table) has the consequence that relatively high material losses have to be accepted and through the sealing strips to be provided on the filling shoe, for example metal abrasion, reaches the product to be manufactured. The so-called black spots appear on the tablet surface.
  • Dust arising in the press chamber of the device is first deposited on the free surfaces of the greased upper punches. It falls off during an ongoing process and reaches the filling shoe via the die table. This effect also leads to the previously mentioned "black spots" on the tablet surface.

Aufgabe der Erfindung ist es daher, eine Vorrichtung zur Herstellung von Tabletten oder Preßlingen an die Hand zu geben, mit der Tabletten oder Preßlinge ohne die sogenannten "schwarzen Flecken" auf der Tablettenoberfläche herstellbar sind.The object of the invention is therefore a device for producing tablets or tablets to hand, with the tablets or tablets without the so-called "Black spots" can be produced on the tablet surface.

Diese Aufgabe wird ausgehend von einer gattungsgemäßen Vorrichtung gemäß dem Oberbegriff des Anspruchs 1 durch die kennzeichnenden Merkmale des Hauptanspruchs gelöst. Die zueinander beweglichen Preßwerkzeuge sind entgegen bauüblichen Tablettenmaschinen nicht mehr vertikal, sondern horizontal ausgerichtet. Durch diese Maßnahme kann das Auftreten der "schwarzen Flecken" wirksam vermieden werden. Dabei sind die Preßwerkzeuge auf einem in Drehbewegung versetzbaren Rotor angeordnet. Exzentrisch zu der Drehachse des Rotors ist eine Druckrolle gelagert und am Rande des rotierenden Teils der Vorrichtung sind zwei weitere Druckrollen angeordnet, so daß über die exzentrische Druckrolle und die beiden weiteren Druckrollen die beim entsprechenden Durchlauf zwischen ihnen angeordneten Preßwerkzeuge gegeneinander preßbar sind.This task is based on a generic device according to the Preamble of claim 1 by the characterizing features of the main claim solved. The pressing tools, which are movable relative to one another, are conventional Tablet machines no longer aligned vertically, but horizontally. By this measure can effectively prevent the occurrence of the "black spots" become. The pressing tools are rotatable on one Rotor arranged. A pressure roller is mounted eccentrically to the axis of rotation of the rotor and on the edge of the rotating part of the device are two further pressure rollers arranged so that over the eccentric pressure roller and the other two Pressure rollers the pressing tools arranged between them during the corresponding pass are pressed against each other.

Es können auf dem Umfang des Rotors gleichverteilt mehrere im Verhältnis zueinander bewegliche Preßwerkzeugpaare angeordnet sein. Die Befülleinrichtung kann mit dem Rotor derart gekoppelt sein, daß sie mit diesem zusammen in Drehbewegung versetzbar ist. Dabei können Rotor und Befülleinrichtung über die Drehachse miteinander gekoppelt sein. Die Befülleinrichtung kann aus einem bauchig ausgeformten Fülltrichter bestehen, an welchen sich trichterförmig verjüngende Kanäle angesetzt sind, deren verjüngten Enden in eine Einfüllöffnung der jeweiligen Matrize münden. Diese Anordnung des Fülltrichters ermöglicht es, daß die Matrizen mittels Zentrifugalkraft mit dem Tablettiergut befüllt werden. Hierdurch können auch schlecht fließende Materialien gut verarbeitet werden und es kann genauer dosiert werden. There can be several equally distributed on the circumference of the rotor in relation to each other movable pairs of pressing tools can be arranged. The filling device can with be coupled to the rotor such that they rotate together with it is relocatable. The rotor and the filling device can be connected to one another via the axis of rotation be coupled. The filling device can consist of a bulbous shape Filling hoppers exist, on which funnel-shaped tapered channels are attached are, the tapered ends of which open into a filling opening of the respective die. This arrangement of the hopper allows the dies to be centrifugally applied be filled with the tablets. This can also cause poorly flowing Materials are processed well and it can be dosed more precisely.

Vorteilhaft werden die zueinander beweglichen Preßwerkzeuge während iher Rotation durch ihnen jeweils zugeordnete Führungskurven in horizontaler Richtung bewegt. Hierdurch kann bei bestimmten Winkelpositionen ein entspechend jeweils zugeordneter Arbeitstakt durchgeführt werden.The mutually movable pressing tools are advantageous during their rotation moved in the horizontal direction by guide curves assigned to them. As a result, a correspondingly assigned one can be used for certain angular positions Work cycle to be carried out.

Die beiden weiteren Druckrollen können so in einem unterschiedlichen Abstand zu den zugeordneten Preßwerkzeugen angeordnet sein, daß ein unterschiedlich starker Preßdruck erzeugbar ist. Hierdurch kann bei einer bestimmten Winkelposition durch eine erste Druckrolle ein Vorpressen gewährleistet sein und bei einer zweiten Winkelposition kann durch die zweite Druckrolle ein vollständiges Pressen erfolgen.The two other pressure rollers can be at a different distance the associated pressing tools can be arranged that a different strength Press pressure can be generated. This allows through at a certain angular position a first pressure roller can be used to pre-press and at a second angular position complete pressing can be done by the second pressure roller.

Weitere Einzelheiten und Vorteile der Erfindung werden anhand eines in der Zeichnung dargestellten Ausführungsbeispiels näher erläutert. Es zeigen:

Fig. 1:
einen schematischen Schnitt durch einen Teil einer ersten Ausführungsform der erfindungsgemäßen Vorrichtung,
Fig. 2:
eine Draufsicht auf einen Teil der erfindungsgemäßen Vorrichtung gemäß Fig. 1 und
Fig. 3-5:
Detaildarstellungen, die verschiedene Arbeitsschritte der erfindungsgemäßen Vorrichtung erläutern.
Further details and advantages of the invention are explained in more detail with reference to an embodiment shown in the drawing. Show it:
Fig. 1:
2 shows a schematic section through part of a first embodiment of the device according to the invention,
Fig. 2:
a plan view of a part of the device according to the invention according to FIGS. 1 and
Fig. 3-5:
Detail representations that explain different steps of the device according to the invention.

Die in den Fig. 1 und 2 dargestellte Vorrichtung weist eine durch einen hier nicht näher dargestellten Motor angetriebenen Rotor 1 auf, der in Drehrichtung a gemäß Fig. 2 in Drehbewegung versetzbar ist. Auf diesem Rotor sind horizontal ausgerichtet jeweils zwei zueinander beweglich angeordnete Preßwerkzeuge 2, 4 montiert. Die Preßwerkzeuge 2, 4 sind in Form eines inneren Stempels 4 und eines äußeren Stempels 2 gebildet, die in einer entsprechenden Bohrung einer Matrize 3 eintauchen. Auf Umfang des Rotors 1 sind im vorliegenden Ausführungsbeispiel vier Peßwerkzeugpaare, die mit den entsprechenden Matrizen zusammenwirken, angeordnet. Auf einer zentralen Achse A des Rotors 1 ist zusätzlich ein Materialfülltrichter 5 angeordnet, der sich zusammen mit dem Rotor 1 dreht. Während der Drehbewegung des Rotors 1 wird das äußere Preßwerkzeug 2, d.h. der äußere Stempel, über eine äußere Führungskurve 12 (vgl. Fig. 2) relativ zum Rotor 1 in horizontaler Ebene verschoben. Ebenso wird das zweite Preßwerkzeug 4, d.h. der innere Stempel, über eine Führungskurve 11 während der Rotation des Rotors 1 in horizontaler Ebene des Rotors verschoben. Hierdurch nehmen die Preßwerkzeuge 2 und 4 zueinander in Abhängigkeit von der Winkelstellung des Rotors 1 aufgrund der jeweiligen Führungskurven eine unterschiedliche Lage zueinander ein. Dies wird anhand der Dargstellung gemäß Fig. 2 deutlich.The device shown in FIGS. 1 and 2 has one driven by a motor, not shown here Rotor 1, which rotates in the direction of rotation a according to FIG. 2 is relocatable. Aligned horizontally on this rotor in each case two pressing tools movably arranged relative to one another 2, 4 mounted. The pressing tools 2, 4 are in the form of a inner stamp 4 and an outer stamp 2 formed, the Immerse in a corresponding hole in a die 3. The circumference of the rotor 1 in the present exemplary embodiment four pairs of press tools with the corresponding dies interact, arranged. On a central axis A of the rotor 1, a material hopper 5 is additionally arranged, which rotates together with the rotor 1. During the rotation of the rotor 1, the outer press tool 2, i.e. the outer stamp, via an outer guide curve 12 (see FIG. 2) shifted relative to rotor 1 in the horizontal plane. As well the second press tool 4, i.e. the inner stamp, via a guide curve 11 during the rotation of the rotor 1 shifted in the horizontal plane of the rotor. Take this through the pressing tools 2 and 4 to each other depending on the Angular position of the rotor 1 based on the respective guide curves a different position to each other. this will based on the representation of FIG. 2 clearly.

In der Position I sind die beiden Preßwerkzeuge weit voneinander entfernt. Hier wird das Tablettiergut eingefüllt und dosiert. In der Position II sind die Preßwerkzeuge 2 und 4 weiter aufeinander zu bewegt. Hier wird das Tablettiergut zunehmend komprimiert. Um die notwendige Preßkraft aufzuprägen, sind hier zwei Druckrollen 6 und 8 gegenüberliegend angeordnet. In dieser Position erfolgt das Vorpressen der Tablette oder des Preßlings innerhalb der Matrize 3. In der Position III sind die Preßwerkzeuge II und IV noch weiter aufeinander zu bewegt, so daß das Tablettiergut noch weiter komprimiert wird. Hier ist der endgültige Preßdruck zur Bildung der Tablette erreicht. Der endgültige Preßdruck wird durch die Druckrolle 6 und die Druckrolle 7 aufgebracht (vgl. Fig. 2). Schließlich werden die Preßwerkzeuge durch die Kurvensteuerung so verschoben, daß die fertige Tablette bzw. der Preßling aus der Matrize ausgeworfen werden. Diese Ausstoßposition ist in der Fig. 2 mit IV bezeichnet.In position I the two press tools are far apart away. Here, the tablets are filled and dosed. In position II, the pressing tools 2 and 4 are further moving towards each other. Here, the tableting material is becoming increasingly popular compressed. To apply the necessary pressing force, here two pressure rollers 6 and 8 are arranged opposite one another. The tablet is pre-pressed in this position or the compact within the die 3. In position III are the pressing tools II and IV on each other even further too moved, so that the tableting material is compressed even further becomes. Here is the final compression pressure to form the tablet reached. The final pressing pressure is through the pressure roller 6 and the pressure roller 7 applied (see FIG. 2). Finally the pressing tools are shifted by the cam control, that the finished tablet or the compact from the Die are ejected. This ejection position is in the Fig. 2 labeled IV.

Die Druckrollen 6, 7 und 8 sind verstellbar ausgeführt. Die im mittleren Bereich des Rotors 1 angeordnete Druckrolle 6 ist dabei exzentrisch zur Achse A des Rotors 1 angeordnet, wobei sie in ihrer Exzentrizität verstellbar ist. Die Druckrollen 7 und 8 sind jeweils in ihrem Abstand zum Rotor 1 verstellbar. Durch diese Verstellbarkeit können die Preßkräfte zur Bildung der Tablette bzw. des Preßlings variiert werden. Grundsätzlich dienen die Druckrollen 6, 7 und 8, wie zuvor ausgeführt, dazu, die notwendigen Preßkräfte zu erzeugen und auf die Preßwerkzeuge zu übertragen. Dabei kommt bei jeder Passage des Preßwerkzeugpaares 2, 4 zwischen den jeweils zugeordneten Druckrollen 6 und 8 und 6 und 7 zu der Verdichtung des Matrizeninhalts.The pressure rollers 6, 7 and 8 are adjustable. The in middle region of the rotor 1 is arranged pressure roller 6 arranged eccentrically to the axis A of the rotor 1, wherein its eccentricity is adjustable. The pressure rollers 7 and 8 are each adjustable in their distance from the rotor 1. Due to this adjustability, the pressing forces can form the tablet or the compact can be varied. Basically serve the pressure rollers 6, 7 and 8, as previously stated, to generate the necessary pressing forces and on the pressing tools transferred to. It comes with each passage of the pair of press tools 2, 4 between the respectively assigned pressure rollers 6 and 8 and 6 and 7 on the compression of the matrix content.

Die Befülleinrichtung 5 ist in dem hier dargestellten Ausführungsbeispiel als bauchig ausgeformter Fülltrichter ausgeführt, wobei die Trichterform durch einen im Inneren des Fülltrichters angeordneten Kegel erhalten wird. Zwischen dem Fülltrichter 5 und entsprechenden Einfüllöffnungen 10 in den Matrizen 3 sind sich trichterförmig verjüngende Kanäle 9 ausgebildet. Aufgrund der Fliehkräfte, die infolge der Rotation des Fülltrichters auf die in den sich verjüngenden Enden befindlichen Tablettiergutpartikel wirken, wird eine sichere Förderung und damit Befüllung der Matrizen 3 in der Position I gewährleistet. The filling device 5 is in the embodiment shown here designed as a bellied filling funnel, the funnel shape being formed by an inside of the hopper arranged cone is obtained. Between the hopper 5 and corresponding filling openings 10 in the matrices 3, funnel-shaped channels 9 are formed. Due to the centrifugal forces caused by the rotation of the Filling funnel on those located in the tapered ends Tablets particles act, is a safe promotion and thus filling the matrices 3 in position I guaranteed.

In den Fig. 3-5 sind jeweils verschiedene Arbeitsstellungen der Preßwerkzeuge 2 und 4 zueinander dargestellt. In Fig. 3 wird die Phase der Matrizenbefüllung gezeigt. Diese Darstellung entspricht der Position I in Fig. 2. In Fig. 4 wird die Kompression des Tablettiergutes dargestellt. Diese Phase 2 entspricht den Positionen II und III gemäß Fig. 2. Schließlich wird in Fig. 5 der Ausstoß der fertigen Tablette T dargestellt. Die Phase III entspricht der Position IV gemäß Fig. 2. Hier wird deutlich, daß die fertige Tablette T durch einen entsprechenden Schlitz 13 aufgrund der Schwerkraft nach ünten in einen hier nicht näher dargestellten Sammelbehälter fallen kann.3-5 are different working positions the pressing tools 2 and 4 shown to each other. 3 the matrix filling phase is shown. This representation corresponds to position I in FIG. 2. In FIG. 4 the Compression of the tableted material shown. This corresponds to phase 2 positions II and III according to FIG. 2. Finally the output of the finished tablet T is shown in FIG. Phase III corresponds to position IV according to FIG. 2. Here it is clear that the finished tablet T by a corresponding Slit 13 downward due to gravity drop a collecting container, not shown here can.

Claims (6)

  1. Apparatus for producing tablets or pressed articles, having at least in each case two movable pressing tools (2, 4), aligned horizontally in relation to one another, and at least one mould (3), which interacts with said pressing tools, and having a filling arrangement (5, 9) for feeding the tabletting material into the mould, the pressing tools (2, 4) being arranged on a rotor (1) which can be made to rotate, characterized in that a pressure-exerting roller (6) is mounted eccentrically in relation to the axis of rotation of the rotor (1), and in that two further pressure-exerting rollers (7, 8) are arranged on the border of the rotor of the apparatus, with the result that, via the eccentric pressure-exerting roller (6) and the two further pressure-exerting rollers (7, 8), the pressing tools (2, 4) arranged between them as they pass through can be pressed against one another.
  2. Apparatus according to Claim 1, characterized in that a plurality of pairs of pressing tools (2, 4) which can be moved in relation to one another are distributed equally over the circumference of the rotor (1).
  3. Apparatus according to Claim 1 or 2, characterized in that the filling arrangement (5) is coupled to the rotor (1) such that it can be made to rotate together therewith.
  4. Apparatus according to Claim 3, characterized in that the rotor (1) and the filling arrangement (5) are coupled to one another via the axis of rotation.
  5. Apparatus according to one of the preceding claims, characterized in that the filling arrangement (5) comprises a convex filling hopper (5) which is adjoined by channels which taper in a funnel-like manner and of which the tapered ends open out in a filling opening of the mould (3).
  6. Apparatus according to one of the preceding claims, characterized in that the two further pressure-exerting rollers (7, 8) are arranged at different distances from the associated pressing tools (2, 4) such that it is possible to produce a compacting pressure of varied strength.
EP96943935A 1995-12-22 1996-12-12 Device for producing tablets Expired - Lifetime EP0813472B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE29520473U 1995-12-22
DE29520473U DE29520473U1 (en) 1995-12-22 1995-12-22 Device for making tablets
PCT/EP1996/005569 WO1997023347A1 (en) 1995-12-22 1996-12-12 Device for producing tablets

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EP0813472A1 EP0813472A1 (en) 1997-12-29
EP0813472B1 true EP0813472B1 (en) 2001-11-21

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EP96943935A Expired - Lifetime EP0813472B1 (en) 1995-12-22 1996-12-12 Device for producing tablets

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WO (1) WO1997023347A1 (en)

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Publication number Priority date Publication date Assignee Title
IT1292853B1 (en) * 1997-04-08 1999-02-11 Mg 2 Spa MACHINE FOR MULTILAYER TABLETS.
US20030032675A1 (en) * 2001-02-15 2003-02-13 Franz G. Andrew Manufacture of thyroid hormone tablets having consistent active moiety amounts
WO2003020499A1 (en) 2001-09-05 2003-03-13 Courtoy Nv A rotary tablet press and a method of cleaning such a press
US20040052843A1 (en) * 2001-12-24 2004-03-18 Lerner E. Itzhak Controlled release dosage forms
NZ552513A (en) * 2001-12-24 2008-08-29 Teva Pharma Dosage form with a core tablet of active ingredient sheathed in a compressed annular body of powder or granular material, and process and tooling for producing it
AU2002251085A1 (en) * 2002-03-27 2003-10-13 Bostlan, S.A. Method for the production of high-concentration manganese mini-tablets for alloying aluminum baths and device for implementing said method
US20040026812A1 (en) * 2002-08-12 2004-02-12 Tiy Inc. Apparatus for bench scale tablet-making
EP2127630B1 (en) * 2007-02-19 2013-07-03 Teijin Pharma Limited Transfer board
CN104309154B (en) * 2013-12-17 2017-06-16 深圳市华创精科生物技术有限公司 A kind of double rush rotary tabletting press

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FR352070A (en) * 1905-03-06 1905-08-02 John Treadwell Press for the production of briquettes
US852457A (en) * 1906-07-18 1907-05-07 Robert Schorr Briqueting-machine.
US1448982A (en) * 1921-09-13 1923-03-20 Treadwell John Briquette press
GB1070587A (en) * 1964-09-16 1967-06-01 V Nauciino I I T Electromashin Method and apparatus for compressing flowable powder materials
FR2397227A1 (en) * 1977-07-13 1979-02-09 Thierion Gabriel Compacting machine for vegetable prod. esp. fibrous fodder - has rotary table with cam operated tabletting cylinders and rams
SU770836A1 (en) * 1978-11-30 1980-10-15 Предприятие П/Я В-8906 Automatic machine for tabletting powder
US4403935A (en) * 1980-03-27 1983-09-13 Manesty Machines Limited Tabletting machines
IT1221567B (en) * 1987-12-30 1990-07-12 Ima Spa COMPRESSING MACHINE FOR THE PRODUCTION OF TABLETS
NL9100383A (en) * 1991-03-01 1992-10-01 Derckx Henricus A J M MACHINE FOR MANUFACTURING CANDIES.

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WO1997023347A1 (en) 1997-07-03
US5910324A (en) 1999-06-08
EP0813472A1 (en) 1997-12-29
DE59608266D1 (en) 2002-01-03
DE29520473U1 (en) 1996-03-28

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