EP0813472A1 - Device for producing tablets - Google Patents

Device for producing tablets

Info

Publication number
EP0813472A1
EP0813472A1 EP96943935A EP96943935A EP0813472A1 EP 0813472 A1 EP0813472 A1 EP 0813472A1 EP 96943935 A EP96943935 A EP 96943935A EP 96943935 A EP96943935 A EP 96943935A EP 0813472 A1 EP0813472 A1 EP 0813472A1
Authority
EP
European Patent Office
Prior art keywords
rotor
filling
pressing tools
pressing
die
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP96943935A
Other languages
German (de)
French (fr)
Other versions
EP0813472B1 (en
Inventor
Rudolf Koch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GEA Process Engineering NV
Original Assignee
Courtoy NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Courtoy NV filed Critical Courtoy NV
Publication of EP0813472A1 publication Critical patent/EP0813472A1/en
Application granted granted Critical
Publication of EP0813472B1 publication Critical patent/EP0813472B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/025—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space whereby the material is transferred into the press chamber by relative movement between a ram and the press chamber
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/08—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/12—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds on the circumference of a rotating drum
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
    • B30B15/30—Feeding material to presses
    • B30B15/302—Feeding material in particulate or plastic state to moulding presses
    • B30B15/308—Feeding material in particulate or plastic state to moulding presses in a continuous manner, e.g. for roller presses, screw extrusion presses

Definitions

  • the invention relates to a device for producing tablets or compacts according to the preamble of the claim
  • Automatic devices for the production of tablets are based on the principle that a tablet is compressed into a tablet as a result of a pressing process.
  • two movable punches serve as pressing tools.
  • Known automatic devices for the production of tablets have a vertically aligned lower punch which runs in a die and an upper punch which is inserted into the die only for pressing.
  • the upper punch slides into the die, pushes the powder together and presses the tablet.
  • the thickness, strength and gloss of the tablet depend on him and his compression pressure.
  • the depth of insertion and the pressure strength can be regulated.
  • the lower stamp is located inside the die. It limits the filling space downwards. During the pressing process, it usually forms the counter bearing.
  • the matrices are filled using a filling funnel, the bottom part of which is called a filling shoe.
  • the filling principle (fixed filling shoe on rotating matrix table) has the consequence that relatively high material losses have to be accepted and through the sealing strips to be provided on the filling shoe, for example metal abrasion, reaches the product to be manufactured.
  • the so-called black spots appear on the tablet surface.
  • the object of the invention is therefore to provide a device for the production of tablets or compacts with which tablets or compacts can be produced without the so-called "black spots" on the tablet surface.
  • the pressing tools are preferably arranged on a rotor which can be rotated.
  • the filling device can be coupled to the rotor in such a way that it can be rotated together with it.
  • the rotor and the filling device can be coupled to one another via the axis of rotation.
  • the filling device can consist of a bulbous filling funnel, on which funnel-shaped tapering channels are attached, the tapered ends of which open into a filling opening of the respective die. This arrangement of the filling funnel enables the matrices to be filled with the tabletted material by means of centrifugal force. As a result, poorly flowing materials can also be processed well and dosing can be carried out more precisely.
  • the pressing tools that are movable relative to one another are rotated by their respective associated movement curves moved in the horizontal direction.
  • a correspondingly assigned work cycle can be carried out at certain angular positions.
  • a pressure roller can be mounted eccentrically to the axis of rotation of the rotor and two further pressure rollers can be arranged at the edge of the rotating part of the device, so that the eccentric pressure roller and the two further pressure rollers arranged between them during the corresponding passage Pressing tools can be pressed against each other.
  • These two further pressure rollers can be arranged at a different distance from the associated pressing tools in such a way that a different pressing pressure can be generated. In this way, pre-pressing can be ensured at a certain angular position by a first pressure roller, and complete pressing can be carried out by the second pressure roller at a second angular position.
  • FIGS. 1 and 2 a plan view of a part of the device according to the invention according to FIGS. 1 and
  • FIGS. 1 and 2 Detail representations which explain different working steps of the device according to the invention.
  • the device shown in FIGS. 1 and 2 has a rotor 1 which is driven by a motor (not shown here in any more detail) and which can be set in rotation in the direction of rotation a according to FIG. 2.
  • Two pressing tools 2, 4 arranged movably relative to one another are mounted horizontally on this rotor.
  • the pressing tools 2, 4 are formed in the form of an inner punch 4 and an outer punch 2, which are immersed in a corresponding bore in a die 3.
  • four pairs of press tools, which interact with the corresponding matrices, are arranged on the circumference of the rotor 1.
  • a material filling funnel 5, which rotates together with the rotor 1, is additionally arranged on a central axis A of the rotor 1.
  • the outer pressing tool 2, ie the outer punch is displaced in a horizontal plane relative to the rotor 1 via an outer guide curve 12 (cf. FIG. 2).
  • the second press tool 4, ie the inner punch is displaced via a guide curve 11 during the rotation of the rotor 1 in the horizontal plane of the rotor.
  • the pressing tools 2 and 4 are in a different position relative to one another depending on the angular position of the rotor 1 due to the respective guide curves. This becomes clear from the illustration according to FIG. 2.
  • the pressure rollers 6, 7 and 8 are adjustable.
  • the pressure roller 6 arranged in the central region of the rotor 1 is arranged eccentrically to the axis A of the rotor 1, its eccentricity being adjustable.
  • the pressure rollers 7 and 8 are each adjustable in their distance from the rotor 1. This adjustability allows the pressing forces to form the tablet or compact to be varied.
  • the pressure rollers 6, 7 and 8 serve, as previously stated, to generate the necessary pressing forces and to transmit them to the pressing tools.
  • the contents of the die are compressed.
  • the filling device 5 is designed as a bulging filling funnel, the funnel shape being obtained by a cone arranged inside the filling funnel. Channels 9 tapering in a funnel shape are formed between the filling funnel 5 and corresponding filling openings 10 in the matrices 3. Due to the centrifugal forces which act on the tabletting material particles located in the tapering ends as a result of the rotation of the filling funnel, safe delivery and thus filling of the dies 3 in position I is ensured. 3-5, different working positions of the pressing tools 2 and 4 are shown in relation to each other. In Fig. 3 the phase of the matrix filling is shown. This representation corresponds to position I in FIG. 2. The compression of the tableting material is shown in FIG.
  • phase 2 corresponds to positions II and III according to FIG. 2.
  • Phase III corresponds to position IV according to FIG. 2.
  • the finished tablet T can fall down through a corresponding slot 13 due to gravity into a collecting container, not shown here.

Abstract

A device for producing tablets has at least two pressing tools (2, 4) movable towards each other, at least one matrix (3) which co-operates with said tools and a filling device (5, 9) for supplying the material to be turned into tablets to the matrix. The pressing tools which are movable towards each other are horizontally oriented.

Description

Vorrichtung zur Herstellung von Tabletten Device for making tablets
Die Erfindung betrifft eine Vorrichtung zur Herstellung von Tabletten oder Preßlingen nach dem Oberbegriff des AnspruchsThe invention relates to a device for producing tablets or compacts according to the preamble of the claim
1.1.
Automatische Vorrichtungen zur Herstellung von Tabletten basie¬ ren auf dem Prinzip, daß ein Tablettiergut aufgrund eines Pre߬ vorganges zu einer Tablette verpreßt wird. Hierzu dienen zwei bewegliche Stempel als Preßwerkzeuge. Bekannte automatische Vorrichtungen zur Herstellung von Tabletten besitzen vertikal ausgerichtet einen Unterstempel, der in einer Matrize läuft und einen Oberstempel, der in die Matrize nur zur Pressung ein¬ geführt wird. Der Oberstempel gleitet in die Matrize, schiebt das Pulver zusammen und preßt die Tablette. Von ihm und seinem Preßdruck hängen Dicke, Festigkeit und Preßglanz der Tablette ab. Die Einführungstiefe und die Druckstärke lassen sich regu¬ lieren. Der Unterstempel befindet sich innerhalb der Matrize. Er begrenzt den Füllraum nach unten. Während des Preßvorgangs bildet er in der Regel das Gegenlager. Nach Abschluß der Pres¬ sung wird er nach oben geführt und bringt dadurch die Tablette auf den Matrizenrand, wo sie beiseite geschoben wird. Im näch¬ sten Takt fällt der Unterstempel in seine Ausgangsstellung zu¬ rück und der Matrizenraum ist zur Aufnahme der nächsten Fül¬ lung bereit. Die Befüllung der Matrizen erfolgt über einen Fülltrichter, dessen unterster Teil Füllschuh genannt wird.Automatic devices for the production of tablets are based on the principle that a tablet is compressed into a tablet as a result of a pressing process. For this purpose, two movable punches serve as pressing tools. Known automatic devices for the production of tablets have a vertically aligned lower punch which runs in a die and an upper punch which is inserted into the die only for pressing. The upper punch slides into the die, pushes the powder together and presses the tablet. The thickness, strength and gloss of the tablet depend on him and his compression pressure. The depth of insertion and the pressure strength can be regulated. The lower stamp is located inside the die. It limits the filling space downwards. During the pressing process, it usually forms the counter bearing. After completion of the pressing, it is guided upwards and thereby brings the tablet onto the edge of the die, where it is pushed aside. In the next cycle, the lower punch falls back into its starting position and the die space is ready to receive the next filling. The matrices are filled using a filling funnel, the bottom part of which is called a filling shoe.
Diese bekannten Vorrichtungen werden heute in der Regel als Rundlauftablettenmaschinen ausgebildet. Bei diesen Typen steht der Füllschuh des Fülltrichters fest, während die Matrize be¬ weglich ist. Eine runde Horizontalplatte trägt eine Anzahl von Matrizen. Zu jeder Matrize gehören, wie zuvor ausgeführt, ein Ober- und ein Unterstempel. Durch Rollen werden die Stempel jeweils gehoben und gesenkt. Durch Drehung einer horizontalen Platte werden die Matrizen mit ihren Stempeln nacheinander in füllbereite Stellung unter den Füllschuh gebracht.These known devices are generally designed as rotary tablet machines today. This type says the filling shoe of the filling funnel is firm while the die is movable. A round horizontal plate carries a number of matrices. As previously stated, each die has an upper and a lower stamp. The stamps are raised and lowered by rolling. By rotating a horizontal plate, the dies with their stamps are brought one after the other into the ready-to-fill position under the filling shoe.
Rundlauftablettenmaschinen weisen aus verfahrenstechnologi¬ scher Sicht einige gravierende Mängel auf, die aufgrund des zuvor geschilderten Konstruktionsprinzips der Vorrichtung nicht vollständig zu beseitigen sind. Dabei stehen bei der Her¬ stellung von Tabletten zu pharmazeutischen Zwecken oder auch von Preßlingen im Lebensmittelbereich folgende Nachteile im Vordergrund:From a process technology point of view, rotary tablet machines have some serious shortcomings that cannot be completely remedied due to the above-described design principle of the device. The following disadvantages stand in the foreground when producing tablets for pharmaceutical purposes or also as compacts in the food sector:
Eine intensive Vorbehandlung der zu verpressenden Substan¬ zen ist notwendig, um ein gutes Fließverhalten und damit die Dosierbarkeit zu erreichen.Intensive pretreatment of the substances to be pressed is necessary in order to achieve good flow behavior and thus meterability.
Das Füllprinzip ( fixierter Füllschuh auf rotierendem Matri¬ zentisch) hat zur Folge, daß relativ hohe Materialverluste hingenommen werden müssen und durch die am Füllschuh vorzu¬ sehenden Dichtleisten, beispielsweise Metallabrieb ins zu fertigende Produkt gelangt. Es entstehen die sogenannten schwarzen Flecken auf der Tablettenoberfläche.The filling principle (fixed filling shoe on rotating matrix table) has the consequence that relatively high material losses have to be accepted and through the sealing strips to be provided on the filling shoe, for example metal abrasion, reaches the product to be manufactured. The so-called black spots appear on the tablet surface.
Im Preßraum der Vorrichtung entstehender Staub wird zu¬ nächst auf den freien Oberflächen der gefetteten Oberstem¬ pel abgelagert. Er fällt bei andauerndem Prozeß ab und ge¬ langt über den Matrizentisch in den Füllschuh. Auch dieser Effekt führt zu den bereits zuvor genannten "schwarzen Flecken" auf der Tablettenoberfläche. Aufgabe der Erfindung ist es daher, eine Vorrichtung zur Her¬ stellung von Tabletten oder Preßlingen an die Hand zu geben, mit der Tabletten oder Preßlinge ohne die sogenannten "schwar¬ zen Flecken" auf der Tablettenoberfläche herstellbar sind.Dust which arises in the press chamber of the device is first deposited on the free surfaces of the greased upper stamps. It falls off during an ongoing process and reaches the filling shoe via the die table. This effect also leads to the previously mentioned "black spots" on the tablet surface. The object of the invention is therefore to provide a device for the production of tablets or compacts with which tablets or compacts can be produced without the so-called "black spots" on the tablet surface.
Diese Aufgabe wird ausgehend von einer gattungsgemäßen Vorrich¬ tung gemäß dem Oberbegriff des Anspruchs 1 durch die kennzeich¬ nenden Merkmale des Hauptanspruchs gelöst. Demnach ist es der Grundgedanke zur Lösung der Aufgabe, die zueinander bewegli¬ chen Preßwerkzeuge entgegen dem gesamten Stand der Technik nicht mehr vertikal, sondern horizontal auszurichten. Durch diese Maßnahme kann das Auftreten der "schwarzen Flecken" wirk¬ sam vermieden werden.This object is achieved on the basis of a generic device according to the preamble of claim 1 by the characterizing features of the main claim. Accordingly, the basic idea for solving the problem, contrary to the entire prior art, is no longer to align the movable pressing tools vertically, but rather horizontally. This measure effectively prevents the occurrence of the "black spots".
Vorzugsweise sind die Preßwerkzeuge auf einem in Drehbewegung versetzbaren Rotor angeordnet. Dabei können auf dem Umfang des Rotors gleichverteilt mehrere im Verhältnis zueinander bewegli¬ che Preßwerkzeugpaare angeordnet sein. Die Befülleinrichtung kann mit dem Rotor derart gekoppelt sein, daß sie mit diesem zusammen in Drehbewegung versetzbar ist. Dabei können Rotor und Befülleinrichtung über die Drehachse miteinander gekoppelt sein. Die Befülleinrichtung kann aus einem bauchig ausgeform¬ ten Fülltrichter bestehen, an welchen sich trichterförmig ver¬ jüngende Kanäle angesetzt sind, deren verjüngten Enden in eine Einfüllöffnung der jeweiligen Matrize münden. Diese Anordnung des Fülltrichters ermöglicht es, daß die Matrizen mittels Zen¬ trifugalkraft mit dem Tablettiergut befüllt werden. Hierdurch können auch schlecht fließende Materialien gut verarbeitet wer¬ den und es kann genauer dosiert werden.The pressing tools are preferably arranged on a rotor which can be rotated. In this case, several pairs of pressing tools that are movable relative to one another can be arranged on the circumference of the rotor in a uniformly distributed manner. The filling device can be coupled to the rotor in such a way that it can be rotated together with it. The rotor and the filling device can be coupled to one another via the axis of rotation. The filling device can consist of a bulbous filling funnel, on which funnel-shaped tapering channels are attached, the tapered ends of which open into a filling opening of the respective die. This arrangement of the filling funnel enables the matrices to be filled with the tabletted material by means of centrifugal force. As a result, poorly flowing materials can also be processed well and dosing can be carried out more precisely.
Vorteilhaft werden die zueinander beweglichen Preßwerkzeuge während ihrer Rotation durch ihnen jeweils zugeordnete Füh- rungskurven in horizontaler Richtung bewegt. Hierdurch kann bei bestimmten Winkelpositionen ein entsprechend jeweils zuge¬ ordneter Arbeitstakt durchgeführt werden.Advantageously, the pressing tools that are movable relative to one another are rotated by their respective associated movement curves moved in the horizontal direction. As a result, a correspondingly assigned work cycle can be carried out at certain angular positions.
Exzentrisch zu der Drehachse des Rotors kann eine Druckrolle gelagert sein und am Rande des rotierenden Teils der Vorrich¬ tung können zwei weitere Druckrollen angeordnet sein, so daß über die exzentrische Druckrolle und die beiden weiteren Druck¬ rollen die beim entsprechenden Durchlauf zwischen ihnen ange¬ ordneten Preßwerkzeuge gegeneinander preßbar sind. Diese bei¬ den weiteren Druckrollen können so in einem unterschiedlichen Abstand zu den zugeordneten Preßwerkzeugen angeordnet sein, daß ein unterschiedlich starker Preßdruck erzeugbar ist. Hier¬ durch kann bei einer bestimmten Winkelposition durch eine er¬ ste Druckrolle ein Vorpressen gewährleistet sein und bei einer zweiten Winkelposition kann durch die zweite Druckrolle ein vollständiges Pressen erfolgen.A pressure roller can be mounted eccentrically to the axis of rotation of the rotor and two further pressure rollers can be arranged at the edge of the rotating part of the device, so that the eccentric pressure roller and the two further pressure rollers arranged between them during the corresponding passage Pressing tools can be pressed against each other. These two further pressure rollers can be arranged at a different distance from the associated pressing tools in such a way that a different pressing pressure can be generated. In this way, pre-pressing can be ensured at a certain angular position by a first pressure roller, and complete pressing can be carried out by the second pressure roller at a second angular position.
Weitere Einzelheiten und Vorteile der Erfindung werden anhand eines in der Zeichnung dargestellten Ausführungsbeispiels nä¬ her erläutert. Es zeigen:Further details and advantages of the invention are explained in more detail with reference to an embodiment shown in the drawing. Show it:
Fig. 1: einen schematischen Schnitt durch einen Teil einer ersten Ausführungsform der erfindungsge¬ mäßen Vorrichtung,1: a schematic section through part of a first embodiment of the device according to the invention,
Fig. 2: eine Draufsicht auf einen Teil der erfindungsge¬ mäßen Vorrichtung gemäß Fig. 1 und2: a plan view of a part of the device according to the invention according to FIGS. 1 and
Fig. 3-5: Detaildarstellungen, die verschiedene Arbeits¬ schritte der erfindungsgemäßen Vorrichtung erläu¬ tern. Die in den Fig. 1 und 2 dargestellte Vorrichtung weist eine durch einen hier nicht näher dargestellten Motor angetriebenen Rotor 1 auf, der in Drehrichtung a gemäß Fig. 2 in Drehbewe¬ gung versetzbar ist. Auf diesem Rotor sind horizontal ausge¬ richtet jeweils zwei zueinander beweglich angeordnete Preßwerk¬ zeuge 2, 4 montiert. Die Preßwerkzeuge 2, 4 sind in Form eines inneren Stempels 4 und eines äußeren Stempels 2 gebildet, die in einer entsprechenden Bohrung einer Matrize 3 eintauchen. Auf Umfang des Rotors 1 sind im vorliegenden Ausführungsbei¬ spiel vier Peßwerkzeugpaare, die mit den entsprechenden Matri¬ zen zusammenwirken, angeordnet. Auf einer zentralen Achse A des Rotors 1 ist zusätzlich ein Materialfülltrichter 5 angeord¬ net, der sich zusammen mit dem Rotor 1 dreht. Während der Dreh¬ bewegung des Rotors 1 wird das äußere Preßwerkzeug 2, d.h. der äußere Stempel, über eine äußere Führungskurve 12 (vgl. Fig. 2) relativ zum Rotor 1 in horizontaler Ebene verschoben. Eben¬ so wird das zweite Preßwerkzeug 4, d.h. der innere Stempel, über eine Führungskurve 11 während der Rotation des Rotors 1 in horizontaler Ebene des Rotors verschoben. Hierdurch nehmen die Preßwerkzeuge 2 und 4 zueinander in Abhängigkeit von der Winkelstellung des Rotors 1 aufgrund der jeweiligen Führungs¬ kurven eine unterschiedliche Lage zueinander ein. Dies wird anhand der Dargstellung gemäß Fig. 2 deutlich.3-5: Detail representations which explain different working steps of the device according to the invention. The device shown in FIGS. 1 and 2 has a rotor 1 which is driven by a motor (not shown here in any more detail) and which can be set in rotation in the direction of rotation a according to FIG. 2. Two pressing tools 2, 4 arranged movably relative to one another are mounted horizontally on this rotor. The pressing tools 2, 4 are formed in the form of an inner punch 4 and an outer punch 2, which are immersed in a corresponding bore in a die 3. In the present exemplary embodiment, four pairs of press tools, which interact with the corresponding matrices, are arranged on the circumference of the rotor 1. A material filling funnel 5, which rotates together with the rotor 1, is additionally arranged on a central axis A of the rotor 1. During the rotary movement of the rotor 1, the outer pressing tool 2, ie the outer punch, is displaced in a horizontal plane relative to the rotor 1 via an outer guide curve 12 (cf. FIG. 2). Likewise, the second press tool 4, ie the inner punch, is displaced via a guide curve 11 during the rotation of the rotor 1 in the horizontal plane of the rotor. As a result, the pressing tools 2 and 4 are in a different position relative to one another depending on the angular position of the rotor 1 due to the respective guide curves. This becomes clear from the illustration according to FIG. 2.
In der Position I sind die beiden Preßwerkzeuge weit voneinan¬ der entfernt. Hier wird das Tablettiergut eingefüllt und do¬ siert. In der Position II sind die Preßwerkzeuge 2 und 4 wei¬ ter aufeinander zu bewegt. Hier wird das Tablettiergut zuneh¬ mend komprimiert. Um die notwendige Preßkraft aufzuprägen, sind hier zwei Druckrollen 6 und 8 gegenüberliegend angeord¬ net. In dieser Position erfolgt das Vorpressen der Tablette oder des Preßlings innerhalb der Matrize 3. In der Position III sind die Preßwerkzeuge II und IV noch weiter aufeinander zu bewegt, so daß das Tablettiergut noch weiter komprimiert wird. Hier ist der endgültige Preßdruck zur Bildung der Tablet¬ te erreicht. Der endgültige Preßdruck wird durch die Druckrol¬ le 6 und die Druckrolle 7 aufgebracht (vgl. Fig. 2). Schlie߬ lich werden die Preßwerkzeuge durch die Kurvensteuerung so ver¬ schoben, daß die fertige Tablette bzw. der Preßling aus der Matrize ausgeworfen werden. Diese Ausstoßposition ist in der Fig. 2 mit IV bezeichnet.In position I, the two pressing tools are far apart. The tableted material is filled in and dosed here. In position II, the pressing tools 2 and 4 are moved towards each other. Here the tableting material is increasingly compressed. In order to apply the necessary pressing force, two pressure rollers 6 and 8 are arranged opposite one another here. In this position, the tablet or the compact is pre-pressed inside the die 3. In position III, the pressing tools II and IV are still further on one another too moved, so that the tableting material is compressed even further. Here the final pressing pressure for forming the tablet is reached. The final pressing pressure is applied by the pressure roller 6 and the pressure roller 7 (cf. FIG. 2). Finally, the pressing tools are displaced by the cam control in such a way that the finished tablet or the compact is ejected from the die. This ejection position is designated IV in FIG. 2.
Die Druckrollen 6, 7 und 8 sind verstellbar ausgeführt. Die im mittleren Bereich des Rotors 1 angeordnete Druckrolle 6 ist dabei exzentrisch zur Achse A des Rotors 1 angeordnet, wobei sie in ihrer Exzentrizität verstellbar ist. Die Druckrollen 7 und 8 sind jeweils in ihrem Abstand zum Rotor 1 verstellbar. Durch diese Verstellbarkeit können die Preßkräfte zur Bildung der Tablette bzw. des Preßlings variiert werden. Grundsätzlich dienen die Druckrollen 6, 7 und 8, wie zuvor ausgeführt, dazu, die notwendigen Preßkräfte zu erzeugen und auf die Preßwerkzeu¬ ge zu übertragen. Dabei kommt bei jeder Passage des Preßwerk¬ zeugpaares 2, 4 zwischen den jeweils zugeordneten Druckrollen 6 und 8 und 6 und 7 zu der Verdichtung des Matrizeninhalts.The pressure rollers 6, 7 and 8 are adjustable. The pressure roller 6 arranged in the central region of the rotor 1 is arranged eccentrically to the axis A of the rotor 1, its eccentricity being adjustable. The pressure rollers 7 and 8 are each adjustable in their distance from the rotor 1. This adjustability allows the pressing forces to form the tablet or compact to be varied. Basically, the pressure rollers 6, 7 and 8 serve, as previously stated, to generate the necessary pressing forces and to transmit them to the pressing tools. At each passage of the pair of press tools 2, 4 between the respectively assigned pressure rollers 6 and 8 and 6 and 7, the contents of the die are compressed.
Die Befülleinrichtung 5 ist in dem hier dargestellten Ausfüh¬ rungsbeispiel als bauchig ausgeformter Fülltrichter ausge¬ führt, wobei die Trichterform durch einen im Inneren des Füll¬ trichters angeordneten Kegel erhalten wird. Zwischen dem Füll¬ trichter 5 und entsprechenden Einfüllöffnungen 10 in den Matri¬ zen 3 sind sich trichterförmig verjüngende Kanäle 9 ausgebil¬ det. Aufgrund der Fliehkräfte, die infolge der Rotation des Fülltrichters auf die in den sich verjüngenden Enden befindli¬ chen Tablettiergutpartikel wirken, wird eine sichere Förderung und damit Befüllung der Matrizen 3 in der Position I gewährlei¬ stet. In den Fig. 3-5 sind jeweils verschiedene Arbeitsstellungen der Preßwerkzeuge 2 und 4 zueinander dargestellt. In Fig. 3 wird die Phase der Matrizenbefüllung gezeigt. Diese Darstel¬ lung entspricht der Position I in Fig. 2. In Fig. 4 wird die Kompression des Tablettiergutes dargestellt. Diese Phase 2 ent¬ spricht den Positionen II und III gemäß Fig. 2. Schließlich wird in Fig. 5 der Ausstoß der fertigen Tablette T darge¬ stellt. Die Phase III entspricht der Position IV gemäß Fig. 2. Hier wird deutlich, daß die fertige Tablette T durch einen ent¬ sprechenden Schlitz 13 aufgrund der Schwerkraft nach unten in einen hier nicht näher dargestellten Sammelbehälter fallen kann. In the exemplary embodiment shown here, the filling device 5 is designed as a bulging filling funnel, the funnel shape being obtained by a cone arranged inside the filling funnel. Channels 9 tapering in a funnel shape are formed between the filling funnel 5 and corresponding filling openings 10 in the matrices 3. Due to the centrifugal forces which act on the tabletting material particles located in the tapering ends as a result of the rotation of the filling funnel, safe delivery and thus filling of the dies 3 in position I is ensured. 3-5, different working positions of the pressing tools 2 and 4 are shown in relation to each other. In Fig. 3 the phase of the matrix filling is shown. This representation corresponds to position I in FIG. 2. The compression of the tableting material is shown in FIG. This phase 2 corresponds to positions II and III according to FIG. 2. Finally, the discharge of the finished tablet T is shown in FIG. 5. Phase III corresponds to position IV according to FIG. 2. Here it is clear that the finished tablet T can fall down through a corresponding slot 13 due to gravity into a collecting container, not shown here.

Claims

Vorrichtung zur Herstellung von TablettenAnsprüche Device for producing tablet claims
1. Vorrichtung zur Herstellung von Tabletten oder Preßlingen mit mindestens jeweils zwei im Verhältnis zueinander beweg¬ lichen Preßwerkzeugen und mindestens einer mit diesen zu¬ sammenwirkenden Matrize und mit einer Befülleinrichtung zum Zuführen des Tablettiergutes in die Matrize,1. Device for producing tablets or compacts with at least two pressing tools that are movable relative to each other and at least one die interacting with them and with a filling device for feeding the tabletted material into the die,
dadurch gekennzeichnet,characterized,
daß die zueinander beweglichen Preßwerkzeuge horizontal ausgerichtet sind.that the mutually movable pressing tools are aligned horizontally.
2. Vorrichtung nach Anspruch 1, dadurch gekennzeichnet, daß die Preßwerkzeuge auf einem in Drehbewegung versetzbaren Rotor angeordnet sind.2. Device according to claim 1, characterized in that the pressing tools are arranged on a rotatable rotor.
3. Vorrichtung nach Anspruch 2, dadurch gekennzeichnet, daß auf dem Umfang des Rotors gleichverteilt mehrere im Ver¬ hältnis zueinander bewegliche Preßwerkzeugpaare angeordnet sind. 3. Apparatus according to claim 2, characterized in that on the circumference of the rotor evenly distributed a plurality of pressing tool pairs are arranged in relation to each other.
4. Vorrichtung nach Anspruch 2 oder 3, dadurch gekennzeich¬ net, daß die Befülleinrichtung mit dem Rotor derart gekop¬ pelt ist, daß sie mit diesem zusammen in Drehbewegung ver¬ setzbar ist.4. Apparatus according to claim 2 or 3, characterized gekennzeich¬ net that the filling device is gekop¬ pelt with the rotor so that it can be set together with this in rotary motion.
5. Vorrichtung nach Anspruch 4, dadurch gekennzeichnet, daß der Rotor und die Befülleinrichtung über die Drehachse mit¬ einander gekoppelt sind.5. The device according to claim 4, characterized in that the rotor and the filling device are coupled with each other via the axis of rotation.
6. Vorrichtung nach einem der vorangehenden Ansprüche, da¬ durch gekennzeichnet, daß die Befülleinrichtung aus einem bauchig ausgeformten Fülltrichter besteht, an welchem sich trichterförmig verjüngende Kanäle angesetzt sind, deren verjüngten Enden in eine Einfüllöffnung der Matrize mün¬ den.6. Device according to one of the preceding claims, da¬ characterized in that the filling device consists of a bulbous filling funnel, on which funnel-shaped tapered channels are attached, the tapered ends of the mouth into a filling opening of the die.
7. Vorrichtung nach einem der vorangehenden Ansprüche, da¬ durch gekennzeichnet, daß die zueinander beweglichen Pre߬ werkzeuge während ihrer Rotation durch ihnen jeweils zuge¬ ordnete Führungskurven in horizontaler Richtung bewegbar sind.7. Device according to one of the preceding claims, characterized in that the mutually movable pressing tools are movable in the horizontal direction during their rotation by means of guide curves respectively assigned to them.
8. Vorrichtung nach einem der vorangehenden Ansprüche, da¬ durch gekennzeichnet, daß exzentrisch zu der Drehachse des Rotors eine Druckrolle gelagert ist und daß am Rande des rotierenden Teils der Vorrichtung zwei weitere Druckrollen angeordnet sind, so daß über die exzentrische Druckrolle und die beiden weiteren Druckrollen die beim entsprechen¬ den Durchlauf zwischen ihnen angeordneten Preßwerkzeuge gegeneinander preßbar sind.8. Device according to one of the preceding claims, da¬ characterized in that a pressure roller is mounted eccentrically to the axis of rotation of the rotor and that two further pressure rollers are arranged on the edge of the rotating part of the device, so that the eccentric pressure roller and the other two Pressure rollers which can be pressed against one another during the corresponding passage between the pressing tools arranged between them.
9. Vorrichtung nach einem der vorangehenden Ansprüche, da- durch gekennzeichnet, daß die beiden weiteren Druckrollen so in einem unterschiedlichen Abstand zu den zugeordneten Preßwerkzeugen angeordnet sind, daß ein unterschiedlich starker Preßdruck erzeugbar ist. 9. Device according to one of the preceding claims, characterized in that the two further pressure rollers are arranged at a different distance from the associated pressing tools in such a way that a different pressing pressure can be generated.
EP96943935A 1995-12-22 1996-12-12 Device for producing tablets Expired - Lifetime EP0813472B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE29520473U 1995-12-22
DE29520473U DE29520473U1 (en) 1995-12-22 1995-12-22 Device for making tablets
PCT/EP1996/005569 WO1997023347A1 (en) 1995-12-22 1996-12-12 Device for producing tablets

Publications (2)

Publication Number Publication Date
EP0813472A1 true EP0813472A1 (en) 1997-12-29
EP0813472B1 EP0813472B1 (en) 2001-11-21

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EP (1) EP0813472B1 (en)
DE (2) DE29520473U1 (en)
WO (1) WO1997023347A1 (en)

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IT1292853B1 (en) * 1997-04-08 1999-02-11 Mg 2 Spa MACHINE FOR MULTILAYER TABLETS.
US20030032675A1 (en) * 2001-02-15 2003-02-13 Franz G. Andrew Manufacture of thyroid hormone tablets having consistent active moiety amounts
CN1260057C (en) * 2001-09-05 2006-06-21 库尔图瓦股份有限公司 A rotary tablet press and a method of cleaning such a press
US20040052843A1 (en) * 2001-12-24 2004-03-18 Lerner E. Itzhak Controlled release dosage forms
EA006053B1 (en) * 2001-12-24 2005-08-25 Тева Фармасьютикал Индастриес Лтд. A solid dosage form, process for making therefor and tooling
US20050120829A1 (en) * 2002-03-27 2005-06-09 Guerrenabarrena Rafael S.P. Method for the production of high-concentration manganese mini-tablets for alloying aluminum baths and device for implementing said method
US20040026812A1 (en) * 2002-08-12 2004-02-12 Tiy Inc. Apparatus for bench scale tablet-making
ES2432539T3 (en) * 2007-02-19 2013-12-04 Teijin Pharma Limited Transfer table
CN104309154B (en) * 2013-12-17 2017-06-16 深圳市华创精科生物技术有限公司 A kind of double rush rotary tabletting press

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DE29520473U1 (en) 1996-03-28
EP0813472B1 (en) 2001-11-21
US5910324A (en) 1999-06-08
WO1997023347A1 (en) 1997-07-03
DE59608266D1 (en) 2002-01-03

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