EP0609404A1 - Dispositif ambulatoire de micropulverisation generee par ondes ultrasonores. - Google Patents
Dispositif ambulatoire de micropulverisation generee par ondes ultrasonores.Info
- Publication number
- EP0609404A1 EP0609404A1 EP93911829A EP93911829A EP0609404A1 EP 0609404 A1 EP0609404 A1 EP 0609404A1 EP 93911829 A EP93911829 A EP 93911829A EP 93911829 A EP93911829 A EP 93911829A EP 0609404 A1 EP0609404 A1 EP 0609404A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- ultrasonic waves
- liquid
- medium
- propagation
- microdroplets
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
- B05B17/0615—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers spray being produced at the free surface of the liquid or other fluent material in a container and subjected to the vibrations
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
- B05B7/0081—Apparatus supplied with low pressure gas, e.g. "hvlp"-guns; air supplied by a fan
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
- B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
- B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
- B41J2/01—Ink jet
- B41J2/135—Nozzles
- B41J2/14—Structure thereof only for on-demand ink jet heads
- B41J2002/14322—Print head without nozzle
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S261/00—Gas and liquid contact apparatus
- Y10S261/48—Sonic vibrators
Definitions
- Ambulatory micropulverization device generated by ultrasonic waves
- the present invention relates to a micropulverization device of the type comprising an ultrasonic wave generator, a means of focusing the ultrasonic waves at at least one point of the liquid to be micropulverized and close to its surface, a microdroplet formation chamber and a means of diffusion of the microdroplets thus formed.
- ultrasonic spraying technique has been used to generate a mist of microdroplets.
- ultrasonic waves are generated using electromechanical transducers, such as piezoelectric transducers, in a liquid bath.
- the beam of ultrasonic waves * 30 is directed towards the surface of the bath where the rupture of impedance water-air causes a jet of liquid called "Acoustic fountain".
- This phenomenon is accompanied by a mist of microdroplets whose size is between 3 and 6 ⁇ m, created by cavitation or by resonance of the capillary waves of the jet.
- Another type of focusing consists in using a system for concentrating the ultrasonic waves by a lens of the Fresnel type as described in patent US-A-3,433,461.
- the non-linearities of the ultrasonic wave field are used in order to have good spraying at the focusing point.
- the energy distribution between the fundamental frequency (excitation frequency of the generator), the upper harmonics and the sub-harmonics is a function of the propagation distance in the propagation medium. Must therefore provide a minimum propagation distance of the ultrasonic waves if we want to obtain the best possible efficiency at the focusing point.
- the energy required for the generation of ultrasonic waves is high because it is necessary to provide a relatively powerful source of ultrasonic waves to obtain sufficient energy at the focal point of the waves after significant attenuation, ie by the liquid. propagation as is the case in patent DE-B-1,003,147, or by the Fresnel lens in patent US-A-3,433,461. This is why the devices described are supplied by an external source and do not provide an autonomous power source which would make them ambulatory.
- the present invention therefore aims to remedy the above drawbacks by providing an effective micropulverization device, compact and does not require preheating.
- Another object of the invention is to provide a micropulverization device by ultrasonic waves in which the attenuation of the waves is minimized.
- Yet another object of the invention is to provide a micropulverization device as above, having an autonomous power source making the device ambulatory.
- the object of the invention is a micropulverization device of the. "Acoustic fountain" type in which the means for focusing the ultrasonic waves at at least one point of the liquid to be micropulverized and close to its surface is a medium for propagation of the ultrasonic waves without attenuation and the liquid to be micropulverize is in a tank independent of the tank containing the propagation medium.
- the micropulverization device comprises a housing 10 which comprises a tank 12 containing a medium 13 for propagation of the ultrasonic waves without attenuation.
- a cavity 14 is closed by an electromechanical transducer 16 such as a piezoelectric transducer.
- the transducer 16 is supplied at a frequency between 1 and 5 megahertz by an electronic circuit 18 receiving its power supply from the batteries 20.
- the transducer then generates ultrasonic waves in the tank 12. These waves represented by the arrows in the figure are focused by an appropriate reflecting surface 22, of the paraboloid or cylinder type with parabolic director.
- the ultrasonic waves pass through a cassette 24 containing the liquid to be micro-sprayed in order to concentrate at a point of the liquid close to its surface, an "acoustic fountain" 26 in the form of a jet is thus formed on the surface of the liquid to be micro-sprayed above the opening 28 of the cassette 24.
- This jet 26 generates a mist of relatively uniform microdroplets 30 and of a smaller diameter of between 3 and 6 ⁇ m.
- the mist is transported to the inhaler or the diffuser 32 by a ventilator 36.
- the reflection surface 22 is here of the parabolic type, it is possible to optimize the shape of this surface by numerically solving the integral radiation equations associated with the wave equation, although the frequencies used (fundamental and harmonics) are not high enough to allow the use of ray theory (wavelengths too long compared to the radii of curvature).
- the medium 13 for propagation of the ultrasonic waves must be a low density fluid close to 1 in order to obtain good speed of the acoustic waves, and also not to weigh down the device.
- This medium must have a high non-linearity ratio in order to obtain the best possible efficiency at the focal point by using the shortest possible propagation distance of the waves in the propagation medium. It must be incompressible, with a Poisson's ratio greater than 0.49, and must have a weak attenuation of the waves, less than or equal to 1 dB / cm. Thus, if the distance traveled by the waves in the medium is 4 cm (distance desirable for an ambulatory device), the attenuation will be 4 dB.
- a material meeting these characteristics can be a silicone gel of the poly-dimethyl-siloxane type such as the gel Q7 2167 from Dow Corning associated with the gel Q7 2168 or the gel Q7 2218 from Dow Corning also, or an acrylic gel type "sponge" acrylic, or even a poly-acrylamide.
- micropulverization device illustrated in the single figure only has a single reservoir of micropulverization liquid, the device could include several reservoirs of micropulverization liquid containing different micropulverization liquids and several transducers of different characteristics, without going beyond the scope of the invention.
- a micropulverization device can be designed in which the ultrasonic wave generator is a broadband transducer of way to allow the device to adapt to a wide range of micropulverising liquids.
- This membrane is preferably made of a single-component silicone elastomer used by compression molding or of silicone elatomer used by injection.
- the device according to the invention is autonomous, compact, due to the lower quantity of liquid to be sprayed and in the absence of preheating, and can therefore be used on an outpatient basis. It does not require any sterilization and cleaning due to the existence of a material for propagation of the ultrasonic waves permanently in the device. In addition, it allows, thanks to the easy replacement of one cassette by another, to be used for micropulverization of various liquids. It is particularly suitable for pneumology and otolaryngology applications which require uniform microdroplets and a diameter of less than 5 ⁇ m
Landscapes
- Physical Or Chemical Processes And Apparatus (AREA)
- Special Spraying Apparatus (AREA)
- Control And Other Processes For Unpacking Of Materials (AREA)
- Disintegrating Or Milling (AREA)
- Road Signs Or Road Markings (AREA)
- Physical Water Treatments (AREA)
- Cyclones (AREA)
- Percussion Or Vibration Massage (AREA)
- Catching Or Destruction (AREA)
- Pressure-Spray And Ultrasonic-Wave- Spray Burners (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
Abstract
Description
Claims
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9205306A FR2690634B1 (fr) | 1992-04-29 | 1992-04-29 | Dispositif de micro-pulvérisation générée par ondes ultra-sonores. |
FR9205306 | 1992-04-29 | ||
PCT/FR1993/000411 WO1993022068A1 (fr) | 1992-04-29 | 1993-04-28 | Dispositif ambulatoire de micropulverisation generee par ondes ultrasonores |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0609404A1 true EP0609404A1 (fr) | 1994-08-10 |
EP0609404B1 EP0609404B1 (fr) | 1997-01-15 |
Family
ID=9429383
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP93911829A Expired - Lifetime EP0609404B1 (fr) | 1992-04-29 | 1993-04-28 | Dispositif de micropulverisation generee par ondes ultrasonores |
Country Status (13)
Country | Link |
---|---|
US (1) | US5485828A (fr) |
EP (1) | EP0609404B1 (fr) |
JP (1) | JP3547132B2 (fr) |
AT (1) | ATE147664T1 (fr) |
AU (1) | AU663963B2 (fr) |
CA (1) | CA2111569A1 (fr) |
DE (1) | DE69307488T2 (fr) |
DK (1) | DK0609404T3 (fr) |
ES (1) | ES2098037T3 (fr) |
FR (1) | FR2690634B1 (fr) |
GR (1) | GR3022881T3 (fr) |
NO (1) | NO180154C (fr) |
WO (1) | WO1993022068A1 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11650355B2 (en) * | 2017-12-22 | 2023-05-16 | Shenzhen Institutes Of Advanced Technology | Planar lens and manufacturing method for planar lens |
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US6203759B1 (en) | 1996-05-31 | 2001-03-20 | Packard Instrument Company | Microvolume liquid handling system |
US6521187B1 (en) | 1996-05-31 | 2003-02-18 | Packard Instrument Company | Dispensing liquid drops onto porous brittle substrates |
US6537817B1 (en) | 1993-05-31 | 2003-03-25 | Packard Instrument Company | Piezoelectric-drop-on-demand technology |
DE4426264A1 (de) * | 1994-07-25 | 1996-02-01 | Siemens Ag | Verfahren und Vorrichtung zur Erzeugung und Dosierung eines Pulveraerosols |
US6083762A (en) * | 1996-05-31 | 2000-07-04 | Packard Instruments Company | Microvolume liquid handling system |
US6006955A (en) * | 1998-05-13 | 1999-12-28 | Color Access, Inc. | Pump package |
US6196218B1 (en) * | 1999-02-24 | 2001-03-06 | Ponwell Enterprises Ltd | Piezo inhaler |
DE60015847T2 (de) * | 1999-05-25 | 2005-10-27 | Use Techno Corp., Fukuchiyama | Flüssige Zubereitung zum Verdampfen gegen Erhöhung des Blutzuckerspiegels und Verdampfer für dieselbe |
FR2795348B1 (fr) * | 1999-06-22 | 2001-09-14 | Osmooze Sa | Dispositif programmable de diffusion de pics d'odeurs |
US6748944B1 (en) * | 2000-05-03 | 2004-06-15 | Dellavecchia Michael Anthony | Ultrasonic dosage device and method |
US6386462B1 (en) | 2000-07-31 | 2002-05-14 | S. C. Johnson & Son, Inc. | Method and apparatus for dispensing liquids in aerosolized form with minimum spillage |
EP1182292A1 (fr) * | 2000-08-16 | 2002-02-27 | The Procter & Gamble Company | Dispositif pour nettoyer et rafraíchir les tissus avec nébuliseur ultrasonique et nébulisateur ultrasonique |
US6622720B2 (en) * | 2000-12-18 | 2003-09-23 | Xerox Corporation | Using capillary wave driven droplets to deliver a pharmaceutical product |
US7121275B2 (en) * | 2000-12-18 | 2006-10-17 | Xerox Corporation | Method of using focused acoustic waves to deliver a pharmaceutical product |
US8122880B2 (en) * | 2000-12-18 | 2012-02-28 | Palo Alto Research Center Incorporated | Inhaler that uses focused acoustic waves to deliver a pharmaceutical product |
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DK1389137T3 (da) * | 2001-05-21 | 2006-10-30 | Injet Digital Aerosols Ltd | Sammensætninger til lungelægemiddellevering af protein |
WO2003024610A1 (fr) * | 2001-09-19 | 2003-03-27 | Adiga Kayyani C | Procedes et dispositifs de production, d'extraction et de distribution de brume a gouttelettes ultra-fines |
US7231919B2 (en) * | 2001-09-28 | 2007-06-19 | Kurve Technology, Inc. | Particle dispersion device for nasal delivery |
US8122881B2 (en) * | 2002-05-09 | 2012-02-28 | Kurve Technology, Inc. | Particle dispersion device for nasal delivery |
US8545463B2 (en) * | 2003-05-20 | 2013-10-01 | Optimyst Systems Inc. | Ophthalmic fluid reservoir assembly for use with an ophthalmic fluid delivery device |
US7883031B2 (en) * | 2003-05-20 | 2011-02-08 | James F. Collins, Jr. | Ophthalmic drug delivery system |
US8001963B2 (en) * | 2003-09-05 | 2011-08-23 | Kurve Technology, Inc. | Integrated nebulizer and particle dispersion chamber for nasal delivery of medicament to deep nasal cavity and paranasal sinuses |
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JP3988709B2 (ja) * | 2003-10-15 | 2007-10-10 | 松下電器産業株式会社 | 食器洗い機 |
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US8267081B2 (en) * | 2009-02-20 | 2012-09-18 | Baxter International Inc. | Inhaled anesthetic agent therapy and delivery system |
KR101317736B1 (ko) * | 2009-06-22 | 2013-10-15 | 파나소닉 전공 주식회사 | 탄성 표면파를 사용하는 미스트 또는 미세 기포의 발생 방법 및 미스트 또는 미세 기포 발생 장치 |
JP5470514B2 (ja) * | 2009-12-22 | 2014-04-16 | ナノミストテクノロジーズ株式会社 | 超音波霧化方法と霧化装置 |
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US10154923B2 (en) | 2010-07-15 | 2018-12-18 | Eyenovia, Inc. | Drop generating device |
CA2805426C (fr) | 2010-07-15 | 2020-03-24 | Corinthian Ophthalmic, Inc. | Dispositif de generation de gouttelettes |
WO2012009696A2 (fr) | 2010-07-15 | 2012-01-19 | Corinthian Ophthalmic, Inc. | Administration de médicament ophtalmique |
JP2012200534A (ja) * | 2011-03-28 | 2012-10-22 | Panasonic Corp | ミスト発生装置 |
EP2790619A1 (fr) | 2011-12-12 | 2014-10-22 | Corinthian Ophthalmic, Inc. | Mécanisme éjecteur, dispositif éjecteur et procédés d'utilisation |
DE102012213934A1 (de) * | 2012-08-07 | 2014-02-13 | BSH Bosch und Siemens Hausgeräte GmbH | Waschmaschine mit Vorrichtung zur Erzeugung von Wassertropfen sowie Verfahren zu ihrem Betrieb |
CN102961841B (zh) * | 2012-12-05 | 2016-03-09 | 中山大学 | 一种超细水雾全淹没灭火装置及方法 |
KR101655301B1 (ko) * | 2014-01-29 | 2016-09-07 | 인텔렉추얼디스커버리 주식회사 | 부유식 가습기 |
KR101660868B1 (ko) * | 2014-11-21 | 2016-09-28 | 인텔렉추얼디스커버리 주식회사 | 초음파 가습기 |
NZ706864A (en) * | 2015-04-09 | 2016-07-29 | Aft Pharmaceuticals Ltd | A nasal medication delivery device |
AU2016270999B2 (en) * | 2015-06-03 | 2018-07-26 | Novopyxis, Inc. | Fluid delivery devices and methods |
ES2970399T3 (es) * | 2016-04-05 | 2024-05-28 | Liebherr Hausgeraete Ochsenhausen Gmbh | Dispositivo de refrigeración y/o de congelación |
ES2886611T3 (es) * | 2016-04-05 | 2021-12-20 | Liebherr Hausgeraete Ochsenhausen Gmbh | Aparato de refrigeración y/o de congelación |
CN107412939A (zh) * | 2017-03-31 | 2017-12-01 | 赵慧 | 一种家用水汽治疗仪 |
JP7227163B2 (ja) | 2017-06-10 | 2023-02-21 | アイノビア,インコーポレイティド | 流体を取扱い、目に流体を送出するための方法および装置 |
US11549699B2 (en) | 2017-10-03 | 2023-01-10 | Vornado Air, Llc | Portable humidifier |
US20200360957A1 (en) * | 2018-02-27 | 2020-11-19 | Sharp Kabushiki Kaisha | Atomizing device and humidity regulating device |
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-
1992
- 1992-04-29 FR FR9205306A patent/FR2690634B1/fr not_active Expired - Fee Related
-
1993
- 1993-04-28 JP JP51899693A patent/JP3547132B2/ja not_active Expired - Fee Related
- 1993-04-28 DK DK93911829.5T patent/DK0609404T3/da active
- 1993-04-28 CA CA002111569A patent/CA2111569A1/fr not_active Abandoned
- 1993-04-28 ES ES93911829T patent/ES2098037T3/es not_active Expired - Lifetime
- 1993-04-28 WO PCT/FR1993/000411 patent/WO1993022068A1/fr active IP Right Grant
- 1993-04-28 EP EP93911829A patent/EP0609404B1/fr not_active Expired - Lifetime
- 1993-04-28 AT AT93911829T patent/ATE147664T1/de not_active IP Right Cessation
- 1993-04-28 AU AU42872/93A patent/AU663963B2/en not_active Ceased
- 1993-04-28 US US08/170,221 patent/US5485828A/en not_active Expired - Fee Related
- 1993-04-28 DE DE69307488T patent/DE69307488T2/de not_active Expired - Fee Related
- 1993-12-28 NO NO934871A patent/NO180154C/no unknown
-
1997
- 1997-03-21 GR GR970400554T patent/GR3022881T3/el unknown
Non-Patent Citations (1)
Title |
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See references of WO9322068A1 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11650355B2 (en) * | 2017-12-22 | 2023-05-16 | Shenzhen Institutes Of Advanced Technology | Planar lens and manufacturing method for planar lens |
Also Published As
Publication number | Publication date |
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AU4287293A (en) | 1993-11-29 |
DE69307488T2 (de) | 1997-07-10 |
NO934871D0 (no) | 1993-12-28 |
JP3547132B2 (ja) | 2004-07-28 |
AU663963B2 (en) | 1995-10-26 |
FR2690634B1 (fr) | 1994-10-14 |
US5485828A (en) | 1996-01-23 |
EP0609404B1 (fr) | 1997-01-15 |
WO1993022068A1 (fr) | 1993-11-11 |
DE69307488D1 (de) | 1997-02-27 |
ES2098037T3 (es) | 1997-04-16 |
ATE147664T1 (de) | 1997-02-15 |
GR3022881T3 (en) | 1997-06-30 |
NO180154B (no) | 1996-11-18 |
DK0609404T3 (da) | 1997-07-07 |
CA2111569A1 (fr) | 1993-11-11 |
NO180154C (no) | 1997-02-26 |
FR2690634A1 (fr) | 1993-11-05 |
JPH06507836A (ja) | 1994-09-08 |
NO934871L (no) | 1993-12-28 |
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