EP0595855A1 - Proteines peptides allergeniques provenant du pollen du cedre japonais - Google Patents

Proteines peptides allergeniques provenant du pollen du cedre japonais

Info

Publication number
EP0595855A1
EP0595855A1 EP92914823A EP92914823A EP0595855A1 EP 0595855 A1 EP0595855 A1 EP 0595855A1 EP 92914823 A EP92914823 A EP 92914823A EP 92914823 A EP92914823 A EP 92914823A EP 0595855 A1 EP0595855 A1 EP 0595855A1
Authority
EP
European Patent Office
Prior art keywords
cry
cedar pollen
japanese cedar
allergen
fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP92914823A
Other languages
German (de)
English (en)
Inventor
Irwin J. Griffith
Joanne Pollock
Julian F. Bond
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immulogic Pharmaceutical Corp
Original Assignee
Immulogic Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immulogic Pharmaceutical Corp filed Critical Immulogic Pharmaceutical Corp
Publication of EP0595855A1 publication Critical patent/EP0595855A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/16—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

L'invention décrit des séquences d'acide nucléique codant l'allergène principal du pollen de Cryptomeria japonica, Cry j I, ainsi que ses fragments. L'invention décrit également Cry j I purifié, ainsi qu'au moins un de ses fragments produits dans une cellule hôte transformée par une séquence d'acide nucléique codant Cry j I ou au moins un de ses fragments et des fragments de Cry j préparés synthétiquement. Cry j I et ses fragments sont efficaces dans le diagnostic, le traitement et la prévention de la pollinose provoquée par le cèdre japonais.
EP92914823A 1991-07-12 1992-07-10 Proteines peptides allergeniques provenant du pollen du cedre japonais Withdrawn EP0595855A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US72913491A 1991-07-12 1991-07-12
US729134 1991-07-12
US73045291A 1991-07-15 1991-07-15
US730452 1991-07-15
PCT/US1992/005661 WO1993001213A1 (fr) 1991-07-12 1992-07-10 Proteines peptides allergeniques provenant du pollen du cedre japonais

Publications (1)

Publication Number Publication Date
EP0595855A1 true EP0595855A1 (fr) 1994-05-11

Family

ID=27111816

Family Applications (1)

Application Number Title Priority Date Filing Date
EP92914823A Withdrawn EP0595855A1 (fr) 1991-07-12 1992-07-10 Proteines peptides allergeniques provenant du pollen du cedre japonais

Country Status (5)

Country Link
EP (1) EP0595855A1 (fr)
JP (1) JP3575802B2 (fr)
AU (2) AU2300492A (fr)
CA (1) CA2112913A1 (fr)
WO (1) WO1993001213A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000068262A1 (fr) * 1999-05-11 2000-11-16 Kyowa Hakko Kogyo Co., Ltd. Nouvel antigene pollinique

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6982326B1 (en) 1991-07-12 2006-01-03 Immulogic Pharmaceutical Corporation Allergenic proteins and peptides from Japanese cedar pollen
WO1994001560A1 (fr) * 1991-07-12 1994-01-20 Immulogic Pharmaceutical Corporation Proteines et peptides allergenes tires du pollen du cedre du japon
US6090386A (en) * 1991-07-12 2000-07-18 Griffith; Irwin J. T cell peptides of the CRX JII allergen
US5480972A (en) * 1992-10-30 1996-01-02 The University Of Melbourne Allergenic proteins from Johnson grass pollen
JP3474898B2 (ja) * 1993-10-20 2003-12-08 明治乳業株式会社 スギ花粉アレルゲンのｔ細胞エピトープペプチド及びそのアナログペプチド
JP3512452B2 (ja) * 1993-12-21 2004-03-29 株式会社林原生物化学研究所 ポリペプチドとその製造方法並びに用途
JPH07188291A (ja) * 1993-12-27 1995-07-25 Hayashibara Biochem Lab Inc 蛋白質とその製造方法並びに用途
JP3707817B2 (ja) * 1994-12-21 2005-10-19 明治乳業株式会社 ヒノキ花粉アレルゲン
US6737406B1 (en) 1996-03-21 2004-05-18 Circassia, Ltd. Cryptic peptides and method for their identification
JP4176750B2 (ja) * 1996-06-14 2008-11-05 明治乳業株式会社 Ｔ細胞エピトープペプチド
CN1227566A (zh) 1996-06-14 1999-09-01 明治乳业株式会社 T细胞表位肽
EP0958834B1 (fr) * 1996-11-13 2007-07-04 Meiji Dairies Corporation Utilisation d' agent immunotherapeutique à base de peptides
JP2003116556A (ja) * 2001-10-09 2003-04-22 Nippon Zenyaku Kogyo Kk アレルギー性皮膚炎治療剤
JP4686712B2 (ja) * 2005-03-31 2011-05-25 国立大学法人広島大学 スギ花粉アレルゲンの高次構造ＩｇＥエピトープを含むペプチドおよびその利用
CN102753683B (zh) 2009-10-30 2015-04-08 日本制纸株式会社 具有柳杉花粉的免疫原性的蛋白、编码该蛋白的多核苷酸以及它们的用途
AU2011245142B2 (en) 2010-04-30 2016-10-06 Allovate, Llc Methods, articles and kits for allergic desensitization via the oral mucosa
US9724271B2 (en) 2010-04-30 2017-08-08 Allovate, Llc Methods and articles for preventing or reducing risk of developing a hyperallergenic immune system
CA2924714C (fr) 2013-09-19 2024-04-09 Allovate, Llc Dentifrice destine a procurer des allergenes a la muqueuse buccale
BR112021014064A2 (pt) * 2019-01-17 2021-09-21 LETI Pharma S.L. Processo para produção de um extrato alergênico despigmentado, extrato alergênico despigmentado, extrato alergênico despigmentado polimerizado, composição farmacêutica, e vacina

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63159324A (ja) * 1986-12-22 1988-07-02 Lion Corp スギ花粉症用経口ワクチン
JP2594123B2 (ja) * 1987-09-12 1997-03-26 株式会社林原生物化学研究所 減感作剤
JP2838800B2 (ja) * 1989-09-02 1998-12-16 株式会社林原生物化学研究所 減感作剤

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO9301213A1 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000068262A1 (fr) * 1999-05-11 2000-11-16 Kyowa Hakko Kogyo Co., Ltd. Nouvel antigene pollinique

Also Published As

Publication number Publication date
JPH06508994A (ja) 1994-10-13
AU5586096A (en) 1996-08-29
WO1993001213A1 (fr) 1993-01-21
AU2300492A (en) 1993-02-11
CA2112913A1 (fr) 1993-01-21
JP3575802B2 (ja) 2004-10-13

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19940211

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STAA Information on the status of an ep patent application or granted ep patent

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Effective date: 19980203