EP0591038A1 - Pipette zur Entnahme und zur Verteilung von verschiedener Flüssigkeitsmengen - Google Patents

Pipette zur Entnahme und zur Verteilung von verschiedener Flüssigkeitsmengen Download PDF

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Publication number
EP0591038A1
EP0591038A1 EP93402356A EP93402356A EP0591038A1 EP 0591038 A1 EP0591038 A1 EP 0591038A1 EP 93402356 A EP93402356 A EP 93402356A EP 93402356 A EP93402356 A EP 93402356A EP 0591038 A1 EP0591038 A1 EP 0591038A1
Authority
EP
European Patent Office
Prior art keywords
sleeve
push rod
pipette
sheath
rotation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP93402356A
Other languages
English (en)
French (fr)
Other versions
EP0591038B1 (de
Inventor
Eric Jacques Henri Georges Marteau D'autry
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gilson Medical Electronics (france)sa
Original Assignee
Gilson Medical Electronics (france)sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilson Medical Electronics (france)sa filed Critical Gilson Medical Electronics (france)sa
Publication of EP0591038A1 publication Critical patent/EP0591038A1/de
Application granted granted Critical
Publication of EP0591038B1 publication Critical patent/EP0591038B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0224—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type having mechanical means to set stroke length, e.g. movable stops
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/025—Displaying results or values with integrated means
    • B01L2300/026—Drum counters

Definitions

  • the present invention relates to an improvement to a pipette for sampling and dispensing adjustable volumes of liquids.
  • the invention relates more particularly to an improvement to a pipette of the type comprising a pipette body elongated along a longitudinal axis and a piston mounted in translation along this axis inside said pipette body to define a chamber of variable volume opening onto a sampling port, the piston being driven on a limited stroke in the direction of the sampling port by means of a pressure exerted manually on a push rod mounted in translation in the pipette body and in the opposite direction by reaction of means of elastic return until it abuts against an axial end of a metal sleeve extending inside the pipette body along said longitudinal axis.
  • the sleeve is externally threaded and cooperates by screwing with an internal thread of the pipette body so as to move longitudinally when rotated, in order to adjust the stroke in the opposite direction of the piston and the volume of the chamber.
  • the sheath is able to be driven in rotation by a fine adjustment wheel secured thereto and meshes with means for displaying the volume to be dispensed.
  • the push rod is mounted in translation in the sleeve.
  • the volume to be dispensed is usually adjusted using the thumb and forefinger, these two fingers each applying to opposite sides of the fine adjustment wheel, accessible from the outside. through windows provided on two opposite sides of the pipette body.
  • the fine adjustment wheel allows precise adjustment of the volume to be dispensed but in return can only be driven, with each action of the thumb and forefinger, on a limited angle of rotation linked to the width of the windows provided on the pipette body.
  • the present invention relates to an improved pipette, overcoming the aforementioned drawbacks, in particular which is easily adjustable by an operator wearing gloves and presents a possibility of rapid adjustment of the volume to be dispensed.
  • the push rod has on a part at least of its length a non-symmetrical section of revolution, and the sleeve is made integral, by means of attachment, with a sleeve coaxial with the sleeve and in which the part of non-symmetrical section of revolution of the push rod is also engaged, the sleeve having an internal section of complementary or homologous profile of said part of push rod so as to secure in rotation the push rod and the sheath, while allowing longitudinal movement of the push rod inside the sheath, for rapid adjustment of the volume to be dispensed.
  • the sleeve is glued inside the sheath.
  • the sleeve is received in a bore opening on the axial end of the sleeve serving as a stop for limiting the stroke in the opposite direction of the piston, the radially external surface of the sleeve having recesses for accommodating an adhesive. fixing in the bore of the sleeve.
  • the push rod has a part situated outside the pipette body provided with a push button comprising a quick adjustment wheel provided with means for securing in rotation with said push rod and a cover mounted free to rotate about said longitudinal axis, covering the axial end edge of the wheel located opposite the pipette body.
  • the means for securing in rotation the rapid adjustment wheel on the push rod comprise two longitudinal grooves formed on two diametrically opposite faces of the push rod, engaging with two ribs of complementary profile, projecting from the bearing surface of the quick adjustment dial.
  • the cover is mounted to rotate freely on the push rod and retained axially thereon by complementary shapes.
  • the cover is mounted to rotate freely on the quick adjustment wheel and retained axially thereon by complementary shapes.
  • the pipette shown in FIG. 1, according to the invention, is symmetrical with respect to a median plane corresponding to the section plane of FIG. 1.
  • the pipette comprises a pipette body elongated in the direction of a longitudinal axis L, contained in the aforementioned median plane, consisting of a housing 10 and a sampling tube 20 removably linked by a nut 30 engaged on the sampling tube 20 and coming engaged with an external thread provided on the housing 10.
  • the sampling tube 20, symmetrical of revolution about the longitudinal axis L, has from its upper end, adjacent to the housing 10, a succession of stepped internal walls 26, 24, 25 defining three respective conduits of decreasing diameters.
  • the sampling tube 20 receives a piston 40, mounted in translation inside of it.
  • the piston 40 defines, with the conduits formed by the stepped walls 24 and 25, a chamber 22 of variable volume opening onto an orifice 21 located at the lower end of the sampling tube 20.
  • the sampling tube 20 receives at its lower end, from removably, a disposable tubular end piece not shown communicating in a sealed manner with the withdrawal orifice 21 and intended to contain the liquid to be withdrawn and then to be dispensed. This end piece is held by friction on the external surface of the wall 25 of the sampling tube 20.
  • the latter has at its upper end a radial flange 23 which abuts with the nut 30.
  • the piston 40 preferably consisting of a metal cylinder of diameter corresponding to the diameter of the conduit formed by the wall 24, is integral with the lower end of a piston rod 41 mounted in translation in the pipette body.
  • the piston rod 41 has at its upper end an enlarged cylindrical part 48, the end edge of which serves as a bearing surface at one end 51 of a push rod 50 as will be seen hereinafter.
  • the end edge 42 is bordered radially on its periphery by a radial flange 42a projecting.
  • the piston 40 is driven in the direction of the sampling orifice 21 under the action of a pressure exerted manually on the push rod 50, mounted in translation in the housing 10, the end of the push rod 50 opposite to that coming to bear on the edge 42 being provided for this purpose with a push button 70.
  • the piston 40 is returned in displacement in the opposite direction by reaction of springs 43 and 44 acting on the piston rod 41 and the pipette body, up to abut against an axial end 61 of a metal sleeve 60, mounted inside the housing 10 and inside which freely moves in longitudinal translation the aforementioned push rod 50.
  • the sleeve 60 has a threaded external surface cooperating with an internal thread 68 of the housing 10, so that the drive in rotation of the sleeve 60, around the longitudinal axis L causes its displacement along this axis and consequently the adjustment. of the stroke in the opposite direction of the piston 40, therefore adjusting the volume of the sampling chamber 22. More specifically, the piston rod 41 passes through two washers 46 and 47 located in the pipette body, the washer 46 being kept fixed in the pipette body by clamping its periphery between the adjacent ends of the housing 10 and the sampling tube 20, the washer 47 being mounted in translation along the piston rod 41 between the washer 46 and the piston 40 in the conduit formed by the wall 26 of the tube 20.
  • the spring 43 is disposed in the housing 10 around the piston rod 41 and its enlarged cylindrical part 48, comes into abutment at one end against the glue ette radial 42a and in abutment by the other end against the washer 46.
  • the spring 44 is mounted around the piston rod 41 and is interposed axially between the washer 47 and an axial end of a sleeve 45, placed in the conduit formed by the wall 26, between the latter and the piston 40, the other axial end of this sleeve 45 coming, via an O-ring 49, in abutment against the transverse flank delimiting the stepped walls 24 and 26
  • the enlarged cylindrical part 48 of the piston rod 41 has a diameter less than the diameter of the hole in the washer 46 but greater than the diameter of the hole in the washer 47 so as to pass through the washer 46 when the push rod 50 drives the piston rod 41 and then come, by abutment on the washer 47, compress the spring 44.
  • the spring 44 has a stiffness constant much greater than the spring 43 so as to delimit for the pressed operator nt on the push button 70 two successive strokes for the piston, a first stroke, corresponding to the compression of the spring 43 until the enlarged cylindrical part 48 of the piston rod 41 comes up against the washer 47 and to the variation of the volume of the chamber 22 of the quantity to be withdrawn or to be distributed, and a second harder stroke, corresponding to the compression of the spring 44. This latter stroke is used to expel any drops of liquid retained by capillarity in the disposable tip .
  • the sleeve 60 is provided longitudinally, on its outer surface, with a groove 65 to mesh display means 90 of the volume dispensed.
  • these display means 90 housed in the housing 10, comprise a drum of units 91, integral in rotation with the sheath 60, and drums of tens 92 and hundreds 93 driven by the drum of units 91 by means gear teeth 96 provided on the drums and ratchets 97 mounted on an axis 95 parallel to the axis L, in a manner known per se and not described in more detail.
  • a transparent window 94 is provided in the housing 10 to allow the operator to read the volume to be dispensed.
  • the sleeve 60 is provided, at its axial end opposite the end 61 serving as a stop for the edge 42, with a fine adjustment wheel 100, integral in rotation with the sleeve 60.
  • the wheel 100 is located inside 'A housing 13 provided in the housing 10, leading to two access windows 19 used to actuate the wheel 100 from outside the housing 10.
  • the wheel 100 is provided with a braking ring 102 housed in an annular groove provided on the periphery of the wheel 100, forming a brake against the wall 14 of the housing 13.
  • Ejection means are also provided on the pipette to eject the tip after sampling and dispensing a liquid.
  • These ejection means preferably consist, as shown, of a push button 80 mounted in translation in the housing 10, to drive in the direction of the sampling orifice 21 a rod 81, returned in the opposite direction by reaction of a return spring 82, the free end 83 of this rod 81 receiving by friction fitting a curved blade 84, the cross section of which in the form of a portion of a circle centered around the longitudinal axis L substantially matches the external shape of the tube of collection 20.
  • the blade 84 is terminated at its free end 85 by two transverse openings curved around the end of the collection tube 20 for sliding guide the blade 84 on the tube 20 and press on the end edge of a disposable tip engaged on the tube 20 for its ejection.
  • the push rod 50 is stepped along its length to form three parts 50a, 50b, 50c of decreasing respective diameters, extending successively from the end 51 of the push rod 50 acting on edge 42 to push button 70.
  • the part 50a extends from the end 51 over a length greater than that of the sheath 60 to about half the length of the fine adjustment wheel 100.
  • the part 50a is retained at sliding in the sleeve and the wheel 100 by abutment of the transverse flank of the push rod 50 delimiting the parts 50a and 50b against the edge of a retaining ring 101 housed in the wheel 100 and whose internal diameter is greater than the diameter of part 50b but less than the diameter of part 50a.
  • the part 50b preferably has a cylindrical section of revolution around the longitudinal axis L.
  • the part 50c of smaller diameter, carries the push button 70.
  • the part 50a, engaged in the sheath 60 has a cross section of non-symmetrical profile of revolution, preferably hexagonal as shown in Figure 2.
  • the sleeve 60 has, in addition to a central lumen 66, cylindrical of revolution, serving for the passage of the push rod 50, a bore 67 opening out at its axial end 61, to receive a sleeve 110 coaxial with the axis L, the function of which is securing in rotation the push rod 50 and the sheath 60 while allowing a longitudinal displacement of the push rod 50 inside the sheath 60.
  • the sleeve 110 has for this purpose an internal section 111 of profile homologous to the profile of the part 50a of the push rod.
  • FIG. 3 shows a perspective view of a sleeve 110 according to the invention.
  • the sleeve 110 has a cylindrical outer surface 112 of revolution provided with recesses 115 for accommodating an adhesive C for fixing the sleeve in the bore 67 of the sleeve 60.
  • these recesses 115 are constituted by three longitudinal flats formed on the external surface of the sleeve 110, extending axially over only part of the length of the sleeve.
  • the sleeve is made of phenylene polysulphide and the adhesive used is an epoxy adhesive.
  • the push button 70 consists of a quick adjustment wheel 71 coaxial with the part 50c of the push rod 50, provided with means for securing in rotation with the push rod and a cover 72 mounted freely in rotation on the part 50c of the push rod 50, covering the axial end edge 73 of the quick adjustment wheel 71 located opposite the housing 10.
  • the part 50c has a generally cylindrical cross-section of revolution and the means for securing in rotation the wheel 71 with the push rod 50 consist of two longitudinal grooves 54, 55 formed along the diametrically opposite part 50c of the push rod, these longitudinal grooves 54 and 55 engaging with longitudinal ribs of complementary profile projecting from the bearing surface of the quick adjustment wheel 71.
  • the part 50c is provided, as shown in Figure 7, with two annular grooves 58 and 59 axially spaced, cooperating respectively by complementary shapes with annular ribs 74 and 75 projecting from the bearing surfaces of the quick adjustment wheel 71 and the cover 72, for axially retaining these on the part 50c of the push rod 50.
  • the wheel 71 s 'presses on the transverse side of the push rod 50 defining the parts 50b and 50c.
  • the role of the cover 72, mounted free to rotate, is to prevent the push rod from rotating when the operator presses on it and disrupts the volume to be dispensed.
  • the push rod only comprises the stepped parts 50a and 50b, the push button 70 is mounted at the free end of the part 50b, and the cover referenced 72 ′ is mounted free at rotation on the thumbwheel referenced 71 '.
  • the quick adjustment wheel 71 ′ has a radially internal surface 76, serving as a bearing surface on the part 50b, stepped, so as to come axially into abutment on the free end edge 50e of the part 50b.
  • the wheel 71 ' is retained on the push rod by complementarity of shapes between an annular groove 58' provided on the part 50b and an annular rib 74 'projecting from the radially internal surface 76.
  • the mounting of the wheel 71' on the push rod is made by insertion of the wheel 71 'on the push rod 50 and elastic crossing by the annular rib 74', of the region of the rod 50 located between the annular groove 58 'and the end edge 50e.
  • the cover 72 ' is retained axially on the thumb wheel 71' by complementarity of shapes. More specifically, as shown, the wheel 71 'has on its end edge 73' located opposite the housing 10 two cylindrical parts 78 'and 79' stepped and symmetrical of revolution around the longitudinal axis L, serving as bearing surface at the pivoting connection between the wheel 71 'and the cover 72', the latter having two stepped internal surfaces coming to bear respectively on the cylindrical parts 78 'and 79'.
  • the cylindrical part 79 'adjacent to the radially outer knurled surface 77' of the wheel 71 ' joins the cylindrical part 78' by a transverse flank 79'a on which the cover 72 'rests axially.
  • the cover 72 ' is retained axially on the thumbwheel 71' by complementarity of shapes between an annular groove 78'a provided at the base of the cylindrical part 78 'adjacent to the transverse flank 79'a and a annular rib 72'a projecting from the radially inner surface of the cover 72 '.
  • the mounting of the cover 72 'on the wheel 71' leaves a clearance J between the transverse surface of the end edge 73 'adjacent to the knurled surface 77' and the peripheral edge of the cover 72 ', thus facilitating the free rotation of the cover 72 'on the thumb wheel 71'.
  • a pipette according to the invention thanks to the coupling in rotation of the push rod 50 and the sleeve 60 by means of the sleeve 110, allows rapid adjustment of the volume to be dispensed, even by an operator wearing the gloves.

Landscapes

  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
EP93402356A 1992-09-28 1993-09-27 Pipette zur Entnahme und zur Verteilung von verschiedener Flüssigkeitsmengen Expired - Lifetime EP0591038B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9211529 1992-09-28
FR9211529A FR2696110B1 (fr) 1992-09-28 1992-09-28 Perfectionnement à une piquette de prélèvement et de distribution de volumes réglables de liquides.

Publications (2)

Publication Number Publication Date
EP0591038A1 true EP0591038A1 (de) 1994-04-06
EP0591038B1 EP0591038B1 (de) 1997-05-07

Family

ID=9433952

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93402356A Expired - Lifetime EP0591038B1 (de) 1992-09-28 1993-09-27 Pipette zur Entnahme und zur Verteilung von verschiedener Flüssigkeitsmengen

Country Status (5)

Country Link
US (1) US5413006A (de)
EP (1) EP0591038B1 (de)
JP (1) JP3500458B2 (de)
DE (1) DE69310470T2 (de)
FR (1) FR2696110B1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112930229A (zh) * 2018-08-31 2021-06-08 贝克曼库尔特有限公司 高体积和低体积的精确移液器

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US5614153A (en) * 1995-05-26 1997-03-25 Rainin Instrument Co., Inc. Pipette tip ejector
JP3699749B2 (ja) * 1995-06-09 2005-09-28 セーラー万年筆株式会社 ピペット
WO1998011988A1 (en) * 1996-09-19 1998-03-26 Bel-Art Products, Inc. Pipettor tip ejection
US6499363B1 (en) 1997-12-12 2002-12-31 The Sailor Pen Co., Ltd. Tip for pipette and pipette with the same
WO2000044497A1 (en) 1999-01-29 2000-08-03 Genomic Instrumentation Services, Inc. Pipetter
US6428750B1 (en) * 2000-02-17 2002-08-06 Rainin Instrument, Llc Volume adjustable manual pipette with quick set volume adjustment
FR2807345B1 (fr) * 2000-04-07 2002-07-12 Gilson Sa Pipette de prelevement a demontage simplifie
FR2807344B1 (fr) * 2000-04-07 2002-12-06 Gilson Sa Pipette de prelevement a mecanisme de reglage du volume de prelevement
FR2807341B1 (fr) * 2000-04-07 2002-07-12 Gilson Sa Pipette de prelevement d'echantillons liquides a ejecteur demontable
FR2807342B1 (fr) * 2000-04-07 2002-07-12 Gilson Sa Pipette de prelevement a ejecteur de cone
FR2807340B1 (fr) * 2000-04-07 2002-12-06 Gilson Sa Pipette de prelevement d'echantillons liquides a mecanisme d'ejecteur de cone
FR2807343B1 (fr) * 2000-04-07 2002-12-06 Gilson Sa Pipette de prelevement munie de moyens de reglage du volume a prelever
FI20002241A0 (fi) * 2000-10-11 2000-10-11 Labsystems Oy Säädettävä pipetti
JP4317816B2 (ja) * 2002-07-23 2009-08-19 プロテダイン・コーポレーション 材料取り扱い工具
ATE365075T1 (de) * 2003-08-19 2007-07-15 Socorex Isba S A Mechanische kolbenpipette
US7175813B2 (en) * 2003-12-31 2007-02-13 Rainin Instrument, Llc Volume adjustable manual pipette with quick set volume adjustment
DE102004003434B4 (de) * 2004-01-21 2006-06-08 Eppendorf Ag Pipettiervorrichtung mit einer Verdrängungseinrichtung und einer damit lösbar verbundenen Antriebseinrichtung
GB0420256D0 (en) 2004-09-13 2004-10-13 Cassells John M Method and apparatus for sampling and analysis of fluids
KR100624492B1 (ko) * 2004-10-20 2006-09-15 코아스템(주) 피펫
US20090055131A1 (en) * 2005-04-20 2009-02-26 Shmuel Bukshpan Automatic recording volume measurement apparatus
DE102005033378B4 (de) * 2005-07-16 2012-05-31 Eppendorf Ag Kolbenhubpipette
BRPI0617120A2 (pt) * 2005-08-26 2011-07-12 Miles Athol Blackwood-Sewell pipeta e método
GB0605003D0 (en) * 2006-03-13 2006-04-19 Microsample Ltd Method and apparatus for piercing the skin and delivery or collection of liquids
US20080223108A1 (en) * 2007-03-13 2008-09-18 Masashi Kobayashi Pipette and sealing mechanism for plunger
US20090076128A1 (en) * 2007-09-15 2009-03-19 Protia Llc Deuterium-enriched topiramate
FI120672B (fi) * 2008-03-28 2010-01-29 Thermo Fisher Scientific Oy Nupillinen pipetti
DE102008048252A1 (de) * 2008-09-12 2010-04-15 Eppendorf Ag Pipettiervorrichtung
AU2010209763B2 (en) 2009-01-30 2016-05-12 Mycartis N.V. Biomarker for diagnosis, prediction and/or prognosis of acute heart failure and uses thereof
AU2010309808B2 (en) 2009-10-21 2016-04-28 Mycartis Nv Biomarker for diagnosis, prediction and/or prognosis of acute heart failure and uses thereof
JP2011115759A (ja) * 2009-12-07 2011-06-16 Fukae Kasei Kk ピペット装置
JP2011149767A (ja) * 2010-01-20 2011-08-04 Fukae Kasei Kk ピペット装置
US20110237513A1 (en) 2010-03-26 2011-09-29 Pronota N.V. Ltbp2 as a biomarker for renal dysfunction
JP2013524251A (ja) 2010-04-13 2013-06-17 プロノタ エヌ．ヴェ． 妊娠高血圧疾患のバイオマーカー
FR2980123B1 (fr) * 2011-09-19 2013-10-11 Gilson Sas Pipette a deplacement positif presentant une fonction d'ejection amelioree
FI123652B (fi) 2011-10-20 2013-08-30 Thermo Fisher Scientific Oy Lukittava pipetti
WO2014058880A1 (en) * 2012-10-09 2014-04-17 Misono Kunio Stirring devices
FR3003643B1 (fr) * 2013-03-25 2015-04-17 Gilson Sas Systeme de pipetage a deplacement positif presentant une fonction d'ejection amelioree
FR3012883B1 (fr) 2013-11-07 2015-12-25 Gilson Sas Systeme de pipetage a deplacement positif, presentant une conception facilitant la prehension du piston de l'ensemble capillaire-piston
USD798469S1 (en) * 2014-06-26 2017-09-26 Gilson Sas Pipette
FR3040896B1 (fr) * 2015-09-15 2017-10-13 Gilson Sas Pipette de prelevement comprenant un organe de commande a double fonction d'ejection de cone et de deverrouillage du systeme de reglage de volume
US10744498B2 (en) * 2017-09-19 2020-08-18 Mettler-Toledo Rainin, LLC Pipette quickset volume adjustment mechanism
JP7228576B2 (ja) * 2017-09-19 2023-02-24 メトラー－トレド・ライニン，エルエルシー ピペットのクイックセットボリューム調整機構
CN114451365B (zh) * 2022-01-23 2022-11-18 浙江大学 基于深海潜水器的推杆密封式宏生物诱捕保压取样器

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US5018394A (en) * 1990-01-10 1991-05-28 Gilson Warren E Continuously adjustable diluting device for mixing predetermined volumes of liquid

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FR2203680A1 (de) * 1972-10-24 1974-05-17 Gilson Warren
US4141250A (en) * 1976-05-10 1979-02-27 Marteau D Autry Eric Plural piston, adjustable diluting device having a volume indicator assembly
US4395921A (en) * 1981-06-26 1983-08-02 Scientific Manufacturing Industries, Inc. Adjustable volume liquid dispenser
US4672857A (en) * 1985-09-10 1987-06-16 Labindustries, Inc. Liquid microdispenser
US5018394A (en) * 1990-01-10 1991-05-28 Gilson Warren E Continuously adjustable diluting device for mixing predetermined volumes of liquid

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112930229A (zh) * 2018-08-31 2021-06-08 贝克曼库尔特有限公司 高体积和低体积的精确移液器
US11872552B2 (en) 2018-08-31 2024-01-16 Beckman Coulter, Inc. High and low volume precision pipettor with improved accuracy

Also Published As

Publication number Publication date
JP3500458B2 (ja) 2004-02-23
FR2696110A1 (fr) 1994-04-01
EP0591038B1 (de) 1997-05-07
JPH06210188A (ja) 1994-08-02
FR2696110B1 (fr) 1994-12-09
DE69310470T2 (de) 1997-12-18
US5413006A (en) 1995-05-09
DE69310470D1 (de) 1997-06-12

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