EP0321786B1 - Composition pour application externe - Google Patents

Composition pour application externe Download PDF

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Publication number
EP0321786B1
EP0321786B1 EP88120474A EP88120474A EP0321786B1 EP 0321786 B1 EP0321786 B1 EP 0321786B1 EP 88120474 A EP88120474 A EP 88120474A EP 88120474 A EP88120474 A EP 88120474A EP 0321786 B1 EP0321786 B1 EP 0321786B1
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EP
European Patent Office
Prior art keywords
phosphate
composition
iii
formula
metal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP88120474A
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German (de)
English (en)
Other versions
EP0321786A3 (en
EP0321786A2 (fr
Inventor
Tomohiko Sano
Yuji Suzuki
Kayoko Iwata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kao Corp
Original Assignee
Kao Corp
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Publication date
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Publication of EP0321786A2 publication Critical patent/EP0321786A2/fr
Publication of EP0321786A3 publication Critical patent/EP0321786A3/en
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Publication of EP0321786B1 publication Critical patent/EP0321786B1/fr
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02—Preparations containing skin colorants, e.g. pigments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/12—Face or body powders for grooming, adorning or absorbing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations

Definitions

  • This invention relates to a composition for external application, and, more particularly, to a composition in a form of an emulsion or cream, in which characteristics inherent to a powder are fully exhibited.
  • the composition can be used for external application, for example, as a skin cosmetic, providing an excellent feeling upon use.
  • Make-up cosmetics oily cosmetics into which powders are formulated and carmine lotions. are given as compositions for external application utilizing characteristics inherent in powders.
  • an object of this invention is to provide an emulsion-like or creamy composition for external application prepared by applying a shear force to an aqueous suspension comprising 0.1 to 20% by weight of one or more polyvalent metal alkyl phosphates.
  • a more specific object of this invention is to provide said emulsion-like or creamy composition having a viscosity of 0.01 Pa ⁇ s (0.1 poise) or more at 30°C.
  • the polyvalent metal alkyl phosphate used as a powder component of the composition of this invention is prepared, by the reaction of (1) an alkyl phosphate represented by the following formula (I) or (II): wherein R1, R2, and R3 independently represent a linear or branched, saturated or unsaturated hydrocarbon group having a C4 ⁇ 38 carbon atom content; X1, X2, and X3 independently represent a hydrogen atom, an alkali metal, or an amine; and a, b, and c independently represent an integer of 0 to 10; and (2) a metal salt represented by the following formula (III): M m Y n (III) wherein M represents a metal other than an alkali metal, Y represents an organic or inorganic anion, and m and n each represent an integer corresponding to the valence of Y and M.
  • R1, R2, and R3 independently represent a linear or branched, saturated or unsaturated hydrocarbon group having a C4 ⁇ 38 carbon atom content
  • R1, R2, and R3 in formulae (I) and (II) are hydrocarbon groups having 4 to 38 carbon atoms. Those having carbon atoms of 8 or more are especially preferable. If the carbon atom content of the hydrocarbon groups is less than 4, metal salts of the alkyl phosphate become too sticky, rendering a lower smoothness and extendability, sometimes providing only insufficient water-repellence.
  • favorable hydrocarbon groups are octyl, nonyl, decyl, dodecyl, undecyl, tridecyl, tetradecyl, pentadecyl, hexadecyl, heptadecyl, octadecyl, nonadecyl, eicosyl, heneicosyl, docosyl, tricosyl, tetracosyl, pentacosyl, hexacosyl, heptacosyl, octacosyl, nonacosyl, triacontyl, hentriacontyl, dotriacontyl, octenyl, nonenyl, decenyl, dodecenyl, undecenyl, tridecenyl, tetradecenyl, pentadecenyl, hexadecenyl, heptadecenyl,
  • Alkali metals such as potassium and sodium, and amines, including monoethanolamine, diethanolamine, triethanolamine, triisopropanolamine, morphorine and arginine, are given as preferable groups represented by X1, X2, and X3 in formulae (I) and (II).
  • M in formula (III) represents a metal other than an alkali metal, and includes alkali earth metals such as Mg, Ca, Sr and Ba; bivalent transition metals such as Zn, Cu, Ni, Co, Fe, Mn, Cd, Pb, Cr and Ti; as well as Al.
  • alkali earth metals such as Mg, Ca, Sr and Ba
  • bivalent transition metals such as Zn, Cu, Ni, Co, Fe, Mn, Cd, Pb, Cr and Ti
  • Al especially preferable metals are Ca, Mg, Ba, Zn, and Al.
  • Y in formula (III) are inorganic anions, such as halogens, SO4, NO3, CO3, PO4, and OH; and organic carboxylic acid anions such as acetic acid, propionic acid and citric acid.
  • particularly preferable anions are halogens, SO4, PO4, NO3, and CO3.
  • a metal salt represented by formula (III) a water soluble one is preferable.
  • various components may be formulated into the composition for external application of the present invention as appropriate, including various kinds of cosmetic oils, surface active agents, humectants, antiseptics, antioxidants, and perfumes.
  • cosmetic oils are liquid paraffin, petrolatum, paraffin wax, squalane, ceresine wax, bees wax, carnauba wax, candelilla wax, hydrogenated castor oil, olive oil, lanolin, lanolin alcohol, higher alcohols, fatty acids, synthetic esters made from a higher alcohol and a fatty acid, and silicones.
  • a cationic, anionic, amphoteric, or nonionic surface active agent can be formulated into the composition of this invention for the purpose of enhancing its stability.
  • Nonionic surface active agents water soluble polyoxyethylenealkyl ether in particular, are preferable surface active agents.
  • a surface active agent can be added to the composition of this invention by adding the same into an aqueous medium before or after a polyvalent metal alkyl phosphate is added.
  • the addition method particularly preferable for ensuring the stability of the composition and for providing a good feeling on use, however, is to add a surface active agent into either an alkyl phosphate aqueous solution or a metal salt aqueous solution in advance, and then to mix the two solution to form a polyvalent metal alkyl phosphate in the presence of such a surface active agent.
  • nonionic surface active agents which can be used are polyoxyethylene fatty acid ester, polyoxyethylenesorbitan fatty acid ester, sorbitan fatty acid ester, glycerin fatty acid ester, polyoxyethylene hydrogenated castor oil, and polyoxyethylenesorbitol fatty acid ester.
  • Those nonionic surface active agents having an HLB value of 8 or more are preferable.
  • Humectants which may be used include, for example, sorbitol, glycerol, propylene glycol, 1,3-butylene glycol, lactic acid, sodium lactate and polyethylene glycol.
  • Antiseptics include p-oxyalkyl benzoate, sodium benzoate, potassium sorbate, and phenoxy ethanol. Named as examples of antioxidants which can be used are tocopherol, sesamol, sesamolin, and lecithin.
  • composition of the present invention can be used as a medicine for external application which can be applied with ease providing an excellent feeling on use if a water soluble or water dispersible medicinal agent is formulated into it.
  • a surface active agent which is commonly used in a conventional aqueous dispersion system for promoting its stability can be formulated into the composition of this invention.
  • a concentration of a surface active agent as low as possible is desirable.
  • the use of this component in an amount as small as possible is desirable.
  • a cosmetic oil is formulated for the purpose of promoting the feeling of the composition upon use through the reduction of flaky feeling inherent to a powder, too much use of the same may impair the freshness and smoothness which are the advantages of a powder. For this reason, use of a cosmetic oil in an amount as small as possible is desirable.
  • the composition of this invention is particularly suitable as a cosmetic for use in summer.
  • a UV light absorbing agent conventionally used for such a cosmetic can be formulated into the composition of this invention directed toward summer use.
  • composition for external application of this invention can be prepared by adding an alkyl phosphate of formula (I) or (II) and a metal salt of formula (III) to an aqueous medium to produce a polyvalent metal alkyl phosphate in the medium, and by applying a shear force to the solution or the dispersion through mixing or the like procedure by means of a disperser or a homogenizer.
  • Water a mixture of water and a polyol such as glycerol or propylene glycol, or a mixture of water and a lower alcohol such as ethanol or isopropanol can be used as an aqueous medium.
  • a mixture of water and ethanol is preferable in view of the excellent dispersing ability of a polyvalent metal alkyl phosphate and the superior freshness of the produced composition.
  • Proportions in terms of a normal range as well as a preferable range of polyvalent metal alkyl phosphates, optional ingredients, and aqueous media in the composition are given below: Proportions (% by weight) Normal Range Preferable Range Polyvalent metal alkyl phosphate 0.1 - 20 0.5 - 10 Surface active agent 0 - 10 0.1 - 3 Cosmetic oil 0 - 10 0.5 - 5 Humectant, medicinal component, etc. 0 - 20 0 - 10 Ethanol 0 - 30 0.5 - 10 Water 15 - 99 62 - 95
  • composition for external application of this invention have a viscosity of 10 Pa ⁇ s to 1000 Pa ⁇ s (100 to 10,000 poise), as measured by a rotating viscosimeter, e.g. a B-type viscosimeter, at 30°C.
  • the composition for external application of this invention is an emulsion-like or creamy substance having a gloss and a beautiful outward appearance, in which a powdery polyvalent metal alkyl phosphate is dispersed in an aqueous medium.
  • the composition exhibits favorable characteristics inherent to a powder such as excellent extendability, good smoothness, stickilessness, slipperiness as well as superior freshness.
  • disodium monocetyl phosphate (molecular weight: 366) was added and stirred at 40°C.
  • 5.5 g of ZnSO4.7H2O (molecular weight: 288) was dissolved into 60 ml of water, and this latter solution was added dropwise into said disodium monocetyl phosphate solution over 30 minutes while stirring.
  • Dispersion of this mixture was effected using a disperser at 40°C for 1 minute, and then the dispersed mixture was allowed to cool to room temperature while stirring, followed by defoaming to produce a white, glossy, homogeneous creamy cosmetic composition having a viscosity of 80 Pa ⁇ s (800 poise) at 30°C.
  • the product possessed good stability, exhibited superior extendability and freshness, and provided a good feeling upon use. The skin felt very smooth after application of this product.
  • Components (1) and (2) were dissolved into 40 g of purified water (10) at 40°C.
  • Component (3) was homogeneously dispersed into the solution.
  • To this dispersion was added dropwise a solution of components (4) to (9), and the remaining purified water (10), and powdery components were dispersed with a disperser for 1 minute. The product was cooled until it defoamed.
  • the product thus produced had a viscosity at 30°C of 153 Pa ⁇ s (1,530 poise), was stable, and provided a good feeling upon use.
  • the amount of component (6) is equivalent to the amount of component (1) plus (2).
  • Components (1) to (8) were dispersed into purified water (13) using a disperser, and then components (9) to (12) were slowly added to the dispersion.
  • the product was a stable lotion and provided a good feeling upon use.
  • the amount of component (6) is equivalent to the amount of component (1) plus (2).
  • Components (1) to (6) were dissolved into 40 g of purified water (11) at 40°C. To the solution were added dropwise a solution of components (7) to (10) in the remaining purified water (11) while stirring. The powdery components were dispersed with a disperser for 1 minute, and the product was allowed to cool.
  • the product thus produced was a white creamy suspension with a viscosity at 30°C of 100 Pa ⁇ s (1,000 poise), was stable, exhibited excellent extendability, and provided a slippery, fresh feeling upon used.
  • the product thus produced had a viscosity at 30°C of 300 Pa ⁇ s (3,000 poise), and exhibited an excellent sebum-absorptive performance in the evaluation by 10 expert female panelists, aged between 20 and 30, with oleaginous skin.
  • Components (4) and (7) were dissolved under heating into purified water (10). To the solution were added components (1), (2), (3), (5) and (6), and the mixture was thoroughly dispersed with a disperser. Components (8) and (9) were the slowly added while stirring. The product was cooled under continued stirring.
  • the product thus produced had a viscosity at 30°C of 200 Pa ⁇ s (2,000 poise), was stable, exhibited an excellent foundational effect, and provided a superior feeling.
  • Components (1) and (2) were dissolved into 40 g of purified water (10) at 40°C.
  • Component (3) was homogeneously dispersed into the solution.
  • To this dispersion was added dropwise a solution of components (5) to (9) and the remaining purified water (10), and the mixture was dispersed with a disperser for 1 minute.
  • This dispersion was mixed with components (11) to (17) which were dispersed into ethanol (4) and the powders in the mixture were homogeneously dispersed under agitation.
  • the product was charged into a glass container and allowed to cool at room temperature.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)

Claims (1)

  1. Procédé de préparation d'une composition crémeuse pour application externe comprenant de 0,1 à 20% en poids d'un ou plusieurs alkylphosphates de métaux polyvalents en mélangeant et en faisant réagir les deux constituants (1) et (2) ci-après en milieu aqueux :
    (1) un alkylphosphate représenté par la formule (I) ou (II) ci-après :
    Figure imgb0008
     où R₁, R₂ et R₃ représentent,indépendamment l'un de l'autre, un groupe hydrocarboné saturé ou non saturé, linéaire ou ramifié ayant de 4 à 38 atomes de carbone; X₁, X₂ et X₃ représentent, indépendamment l'un de l'autre, un atome d'hydrogène, un métal alcalin ou une amine; et a, b et c représentent, indépendamment l'un de l'autre, un nombre entier de 0 à 10;
    (2) un sel métallique représenté par la formule (III) ci-après :



            MmYn



    dans laquelle M représente un métal autre qu'un métal alcalin , Y représente un anion organique ou inorganique produisant un sel métallique soluble dans l'eau de la formule (III), et m et n représentent chacun un nombre entier correspondant à la valence de Y et de M, ladite composition ayant une viscosité comprise dans la plage de 10 Pa.s (100 poises) à 1.000 Pa.s (10.000 poises) mesurée avec un viscosimètre rotatif à 30°C, ledit procédé comprenant l'addition d'un alkylphosphate de la formule (I) ou (II) et d'un sel métallique de la formule (III) à un milieu aqueux afin de produire un alkylphosphate de métal polyvalent dans le milieu, et l'application d'une force de cisaillement à la solution ou à la dispersion en mélangeant celle-ci au moyen d'un dispositif de dispersion ou d'un homogénéiseur.
EP88120474A 1987-12-11 1988-12-07 Composition pour application externe Expired - Lifetime EP0321786B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP62313836A JPH01153607A (ja) 1987-12-11 1987-12-11 皮膚化粧料
JP313836/87 1987-12-11

Publications (3)

Publication Number Publication Date
EP0321786A2 EP0321786A2 (fr) 1989-06-28
EP0321786A3 EP0321786A3 (en) 1989-07-12
EP0321786B1 true EP0321786B1 (fr) 1993-05-19

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EP88120474A Expired - Lifetime EP0321786B1 (fr) 1987-12-11 1988-12-07 Composition pour application externe

Country Status (5)

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US (1) US5057541A (fr)
EP (1) EP0321786B1 (fr)
JP (1) JPH01153607A (fr)
DE (1) DE3881183T2 (fr)
ES (1) ES2041774T3 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8828017D0 (en) * 1988-12-01 1989-01-05 Unilever Plc Topical composition
US8846063B2 (en) * 2008-12-16 2014-09-30 Kimberly-Clark Worldwide, Inc. Personal care composition containing a volatile and a terpene alcohol

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS588545A (ja) * 1981-07-09 1983-01-18 Kao Corp 乳化化粧料
JPS57207538A (en) * 1981-06-15 1982-12-20 Kao Corp Emulsifier and emulsified cosmetic material
JPS59161309A (ja) * 1984-02-16 1984-09-12 Kao Corp 乳化化粧料
GB2160527B (en) * 1984-05-25 1988-02-17 Kao Corp Metal salts of phoshate monoesters
JPS6186940A (ja) * 1984-10-02 1986-05-02 Kao Corp 水中油型乳化組成物
JP2831638B2 (ja) * 1985-04-03 1998-12-02 花王株式会社 洗浄剤組成物
JPS63112695A (ja) * 1986-10-29 1988-05-17 ライオン株式会社 皮膚洗浄剤
JP2526051B2 (ja) * 1987-02-26 1996-08-21 花王株式会社 化粧料組成物

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
List, Arzneiformenlehre 1985, p.295-296 *
Voigt, Lehrbuch der pharmazeutischen Technologie 1982, s. 381 *

Also Published As

Publication number Publication date
DE3881183T2 (de) 1993-12-16
US5057541A (en) 1991-10-15
EP0321786A3 (en) 1989-07-12
EP0321786A2 (fr) 1989-06-28
DE3881183D1 (de) 1993-06-24
JPH0569803B2 (fr) 1993-10-01
JPH01153607A (ja) 1989-06-15
ES2041774T3 (es) 1993-12-01

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