EP0227060A2 - Coin de remplissage pour un appareil de fabrication de capsules de gélatine - Google Patents

Coin de remplissage pour un appareil de fabrication de capsules de gélatine Download PDF

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Publication number
EP0227060A2
EP0227060A2 EP86117728A EP86117728A EP0227060A2 EP 0227060 A2 EP0227060 A2 EP 0227060A2 EP 86117728 A EP86117728 A EP 86117728A EP 86117728 A EP86117728 A EP 86117728A EP 0227060 A2 EP0227060 A2 EP 0227060A2
Authority
EP
European Patent Office
Prior art keywords
filling
filling wedge
wedge
tubes
capsules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP86117728A
Other languages
German (de)
English (en)
Other versions
EP0227060A3 (en
EP0227060B1 (fr
Inventor
Holger Dr. Schönmann
Hans-Peter Eck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Catalent Germany Eberbach GmbH
Original Assignee
Catalent Germany Eberbach GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6788549&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP0227060(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Catalent Germany Eberbach GmbH filed Critical Catalent Germany Eberbach GmbH
Priority to AT86117728T priority Critical patent/ATE61521T1/de
Publication of EP0227060A2 publication Critical patent/EP0227060A2/fr
Publication of EP0227060A3 publication Critical patent/EP0227060A3/de
Application granted granted Critical
Publication of EP0227060B1 publication Critical patent/EP0227060B1/fr
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/16—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using pocketed rollers, e.g. two co-operating pocketed rollers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use

Definitions

  • the invention relates to a filling wedge for a machine for producing gelatin capsules.
  • Such machines have forming rolls arranged in pairs next to one another, which have recessed half-hollow shapes of the capsules to be produced with raised, bead-like edges in their lateral surfaces and ejection stamps for automatically ejecting the finished capsules at the base of the hollow forms.
  • a filler wedge rests in the gusset-shaped area above the two parallel forming rolls, the lower edge of which lies directly above the line of contact of the forming rolls.
  • the filling wedge carries spray nozzles for the filling material in the form of fine slits or holes on this cutting edge or on the side thereof.
  • the nozzles are each connected to a common metering device via a metering pump.
  • Gelatin foils are introduced from the sides into the area under the filling wedge via the two form rollers.
  • the filling wedge which has been electrically heated up to now, has the task of slightly warming the surfaces of the gelatin foils running past them and thereby softening them so that the foils are then welded to one another at the moment of punching out between the raised bead edges of the shaping rollers. This punching is done at the level of the line of contact between the forming rolls.
  • the filling material is injected through the jetting nozzles of the filling wedge between the gelatin foils, which have hitherto been closely adjacent to one another. This causes the gelatin foils to be pressed into the hollow molds and filled with filling material and then immediately sealed.
  • the ejection punches located inside push the finished capsules from the hollow molds and separate them from the remaining film residues, the so-called mesh.
  • the electrical heating elements (resistance heating) arranged in the interior of the filling wedge do not have an equally good contact with the metal of the filling wedge over their entire surface, so that the heat transfer from the heating rods to the filling wedge is non-uniform.
  • a temperature gradient occurs along the filling wedge, i.e. in the axial direction of the forming rolls. Since there are generally several, e.g. If six to eight filling stations are arranged side by side, not all filling stations have the same optimal temperature on the surface of the filling wedge.
  • the surface temperature of the filler wedge has a significant influence on the melting process and the welding process on the gelatin foil, whereby even small temperature changes of approximately ⁇ 1 ° Celsius can lead to the product not being properly welded afterwards.
  • the invention has for its object to eliminate these disadvantages and to provide a filler wedge which has a constant and easily controllable temperature along its surface coming into contact with the gelatin film.
  • the invention is characterized in claim 1.
  • tubes are now arranged inside the filling wedge, through which a liquid heating medium can be passed.
  • a liquid heating medium can preferably be water, but also oil or other flowable media.
  • the liquid heating medium can be passed through the pipes at high speed, so that its temperature gradient from entry to exit can be kept very small. This means that the temperature of the heating medium is practically constant over the entire length of the tubes, so that a uniform, good heat transfer from the liquid heating medium to the tubes and from them to the surface of the filling wedge takes place which comes into contact with the gelatin foils.
  • a filling wedge 11 is arranged, which extends with its lower cutting edge 13 into the narrowing area between the molding rolls 1.
  • the filler wedge 11 has ejection nozzles 15 which, in the exemplary embodiment shown, are directed to both sides and which are connected to a metering device 17 (piston pump or the like) via a line arranged in the filler wedge 11.
  • the filling material F is injected into the resulting capsules K from the metering device 17 via the ejection nozzles 15, as can be seen from FIG. 1.

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Formation And Processing Of Food Products (AREA)
  • Containers And Plastic Fillers For Packaging (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • Package Closures (AREA)
  • Confectionery (AREA)
EP86117728A 1985-12-23 1986-12-19 Coin de remplissage pour un appareil de fabrication de capsules de gélatine Revoked EP0227060B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT86117728T ATE61521T1 (de) 1985-12-23 1986-12-19 Fuellkeil fuer eine maschine zum herstellen von gelatinekapseln.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE8536337U 1985-12-23
DE8536337U DE8536337U1 (de) 1985-12-23 1985-12-23 Füllkeil für eine Maschine zum Herstellen von Gelatinekapseln

Publications (3)

Publication Number Publication Date
EP0227060A2 true EP0227060A2 (fr) 1987-07-01
EP0227060A3 EP0227060A3 (en) 1988-06-29
EP0227060B1 EP0227060B1 (fr) 1991-03-13

Family

ID=6788549

Family Applications (1)

Application Number Title Priority Date Filing Date
EP86117728A Revoked EP0227060B1 (fr) 1985-12-23 1986-12-19 Coin de remplissage pour un appareil de fabrication de capsules de gélatine

Country Status (4)

Country Link
EP (1) EP0227060B1 (fr)
AT (1) ATE61521T1 (fr)
DE (2) DE8536337U1 (fr)
ES (1) ES2021275B3 (fr)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5246635A (en) * 1989-01-26 1993-09-21 R. P. Scherer Corporation Method and apparatus for the manufacture of textured softgels
US5380534A (en) * 1992-08-18 1995-01-10 R.P. Scherer Corporation Soft gelatin medicament capsules with gripping construction
US5422160A (en) * 1989-01-26 1995-06-06 R. P. Scherer Corporation Softgel capsule with a patterned outer shell surface
WO1995017153A1 (fr) * 1993-12-20 1995-06-29 R.P. Scherer Corporation Capsules de gelatine molle contenant une matiere particulaire
WO1996019963A1 (fr) * 1994-12-23 1996-07-04 Basf Aktiengesellschaft Procede de fabrication de comprimes enrobes
EP0935958A1 (fr) * 1998-02-17 1999-08-18 SCA Lohnherstellungs AG Cylindre de formage et méthode d'usinage des cylindres de formage
US6352717B2 (en) 1998-11-17 2002-03-05 Hoffman-La Roche Inc. Process for encapsulating shear sensitive fill masses into capsules and capsules containing shear sensitive fill masses
WO2010108948A1 (fr) * 2009-03-26 2010-09-30 Swiss Caps Rechte Und Lizenzen Ag Procédé et dispositif pour la fabrication de capsules molles
US11541216B2 (en) 2019-11-21 2023-01-03 Massachusetts Institute Of Technology Methods for manufacturing tissue interfacing components
US11712421B2 (en) 2017-05-17 2023-08-01 Massachusetts Institute Of Technology Self-actuating articles

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD75367A (fr) *
DE1185109B (de) * 1962-02-05 1965-01-07 Vitamins Ltd Verfahren zur Herstellung nahtloser Kapseln und Vorrichtung zur Durchfuehrung dieses Verfahrens

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD75367A (fr) *
DE1185109B (de) * 1962-02-05 1965-01-07 Vitamins Ltd Verfahren zur Herstellung nahtloser Kapseln und Vorrichtung zur Durchfuehrung dieses Verfahrens

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5422160A (en) * 1989-01-26 1995-06-06 R. P. Scherer Corporation Softgel capsule with a patterned outer shell surface
US5246635A (en) * 1989-01-26 1993-09-21 R. P. Scherer Corporation Method and apparatus for the manufacture of textured softgels
US5380534A (en) * 1992-08-18 1995-01-10 R.P. Scherer Corporation Soft gelatin medicament capsules with gripping construction
AU686293B2 (en) * 1993-12-20 1998-02-05 R.P. Scherer Corporation Soft gelatin capsules containing particulate material
WO1995017153A1 (fr) * 1993-12-20 1995-06-29 R.P. Scherer Corporation Capsules de gelatine molle contenant une matiere particulaire
AU696878B2 (en) * 1994-12-23 1998-09-17 Basf Aktiengesellschaft The production of covered tablets
WO1996019963A1 (fr) * 1994-12-23 1996-07-04 Basf Aktiengesellschaft Procede de fabrication de comprimes enrobes
CN1113638C (zh) * 1994-12-23 2003-07-09 巴斯福股份公司 包覆片剂的制造方法
EP0935958A1 (fr) * 1998-02-17 1999-08-18 SCA Lohnherstellungs AG Cylindre de formage et méthode d'usinage des cylindres de formage
US6352717B2 (en) 1998-11-17 2002-03-05 Hoffman-La Roche Inc. Process for encapsulating shear sensitive fill masses into capsules and capsules containing shear sensitive fill masses
AU751446B2 (en) * 1998-11-17 2002-08-15 F. Hoffmann-La Roche Ag Process for the manufacture of liquid filled capsules
WO2010108948A1 (fr) * 2009-03-26 2010-09-30 Swiss Caps Rechte Und Lizenzen Ag Procédé et dispositif pour la fabrication de capsules molles
US8727754B2 (en) 2009-03-26 2014-05-20 Swiss Caps Rechte Und Lizenzen Ag Method and device for producing soft capsules
US11712421B2 (en) 2017-05-17 2023-08-01 Massachusetts Institute Of Technology Self-actuating articles
US11541216B2 (en) 2019-11-21 2023-01-03 Massachusetts Institute Of Technology Methods for manufacturing tissue interfacing components

Also Published As

Publication number Publication date
DE3678119D1 (de) 1991-04-18
ES2021275B3 (es) 1991-11-01
EP0227060A3 (en) 1988-06-29
DE8536337U1 (de) 1986-02-13
ATE61521T1 (de) 1991-03-15
EP0227060B1 (fr) 1991-03-13

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