EP0227060A2 - Coin de remplissage pour un appareil de fabrication de capsules de gélatine - Google Patents
Coin de remplissage pour un appareil de fabrication de capsules de gélatine Download PDFInfo
- Publication number
- EP0227060A2 EP0227060A2 EP86117728A EP86117728A EP0227060A2 EP 0227060 A2 EP0227060 A2 EP 0227060A2 EP 86117728 A EP86117728 A EP 86117728A EP 86117728 A EP86117728 A EP 86117728A EP 0227060 A2 EP0227060 A2 EP 0227060A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- filling
- filling wedge
- wedge
- tubes
- capsules
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007903 gelatin capsule Substances 0.000 title claims description 7
- 238000010438 heat treatment Methods 0.000 claims abstract description 21
- 239000007788 liquid Substances 0.000 claims abstract description 12
- 239000000463 material Substances 0.000 claims description 7
- 238000003860 storage Methods 0.000 claims description 4
- 229920000159 gelatin Polymers 0.000 abstract description 21
- 235000019322 gelatine Nutrition 0.000 abstract description 21
- 239000002775 capsule Substances 0.000 abstract description 16
- 238000003466 welding Methods 0.000 abstract description 7
- 239000001828 Gelatine Substances 0.000 abstract 2
- 108010010803 Gelatin Proteins 0.000 description 19
- 239000011888 foil Substances 0.000 description 19
- 239000008273 gelatin Substances 0.000 description 19
- 235000011852 gelatine desserts Nutrition 0.000 description 19
- 239000000945 filler Substances 0.000 description 14
- 239000011324 bead Substances 0.000 description 4
- 238000009826 distribution Methods 0.000 description 4
- 238000000465 moulding Methods 0.000 description 4
- 238000005520 cutting process Methods 0.000 description 3
- 238000007493 shaping process Methods 0.000 description 3
- 238000004080 punching Methods 0.000 description 2
- 230000001427 coherent effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000009969 flowable effect Effects 0.000 description 1
- 108010025899 gelatin film Proteins 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 238000010309 melting process Methods 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
- B30B11/16—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using pocketed rollers, e.g. two co-operating pocketed rollers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
Definitions
- the invention relates to a filling wedge for a machine for producing gelatin capsules.
- Such machines have forming rolls arranged in pairs next to one another, which have recessed half-hollow shapes of the capsules to be produced with raised, bead-like edges in their lateral surfaces and ejection stamps for automatically ejecting the finished capsules at the base of the hollow forms.
- a filler wedge rests in the gusset-shaped area above the two parallel forming rolls, the lower edge of which lies directly above the line of contact of the forming rolls.
- the filling wedge carries spray nozzles for the filling material in the form of fine slits or holes on this cutting edge or on the side thereof.
- the nozzles are each connected to a common metering device via a metering pump.
- Gelatin foils are introduced from the sides into the area under the filling wedge via the two form rollers.
- the filling wedge which has been electrically heated up to now, has the task of slightly warming the surfaces of the gelatin foils running past them and thereby softening them so that the foils are then welded to one another at the moment of punching out between the raised bead edges of the shaping rollers. This punching is done at the level of the line of contact between the forming rolls.
- the filling material is injected through the jetting nozzles of the filling wedge between the gelatin foils, which have hitherto been closely adjacent to one another. This causes the gelatin foils to be pressed into the hollow molds and filled with filling material and then immediately sealed.
- the ejection punches located inside push the finished capsules from the hollow molds and separate them from the remaining film residues, the so-called mesh.
- the electrical heating elements (resistance heating) arranged in the interior of the filling wedge do not have an equally good contact with the metal of the filling wedge over their entire surface, so that the heat transfer from the heating rods to the filling wedge is non-uniform.
- a temperature gradient occurs along the filling wedge, i.e. in the axial direction of the forming rolls. Since there are generally several, e.g. If six to eight filling stations are arranged side by side, not all filling stations have the same optimal temperature on the surface of the filling wedge.
- the surface temperature of the filler wedge has a significant influence on the melting process and the welding process on the gelatin foil, whereby even small temperature changes of approximately ⁇ 1 ° Celsius can lead to the product not being properly welded afterwards.
- the invention has for its object to eliminate these disadvantages and to provide a filler wedge which has a constant and easily controllable temperature along its surface coming into contact with the gelatin film.
- the invention is characterized in claim 1.
- tubes are now arranged inside the filling wedge, through which a liquid heating medium can be passed.
- a liquid heating medium can preferably be water, but also oil or other flowable media.
- the liquid heating medium can be passed through the pipes at high speed, so that its temperature gradient from entry to exit can be kept very small. This means that the temperature of the heating medium is practically constant over the entire length of the tubes, so that a uniform, good heat transfer from the liquid heating medium to the tubes and from them to the surface of the filling wedge takes place which comes into contact with the gelatin foils.
- a filling wedge 11 is arranged, which extends with its lower cutting edge 13 into the narrowing area between the molding rolls 1.
- the filler wedge 11 has ejection nozzles 15 which, in the exemplary embodiment shown, are directed to both sides and which are connected to a metering device 17 (piston pump or the like) via a line arranged in the filler wedge 11.
- the filling material F is injected into the resulting capsules K from the metering device 17 via the ejection nozzles 15, as can be seen from FIG. 1.
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Mechanical Engineering (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Containers And Plastic Fillers For Packaging (AREA)
- Formation And Processing Of Food Products (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicinal Preparation (AREA)
- Package Closures (AREA)
- Confectionery (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT86117728T ATE61521T1 (de) | 1985-12-23 | 1986-12-19 | Fuellkeil fuer eine maschine zum herstellen von gelatinekapseln. |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE8536337U | 1985-12-23 | ||
DE8536337U DE8536337U1 (de) | 1985-12-23 | 1985-12-23 | Füllkeil für eine Maschine zum Herstellen von Gelatinekapseln |
Publications (3)
Publication Number | Publication Date |
---|---|
EP0227060A2 true EP0227060A2 (fr) | 1987-07-01 |
EP0227060A3 EP0227060A3 (en) | 1988-06-29 |
EP0227060B1 EP0227060B1 (fr) | 1991-03-13 |
Family
ID=6788549
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP86117728A Expired - Lifetime EP0227060B1 (fr) | 1985-12-23 | 1986-12-19 | Coin de remplissage pour un appareil de fabrication de capsules de gélatine |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0227060B1 (fr) |
AT (1) | ATE61521T1 (fr) |
DE (2) | DE8536337U1 (fr) |
ES (1) | ES2021275B3 (fr) |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5246635A (en) * | 1989-01-26 | 1993-09-21 | R. P. Scherer Corporation | Method and apparatus for the manufacture of textured softgels |
US5380534A (en) * | 1992-08-18 | 1995-01-10 | R.P. Scherer Corporation | Soft gelatin medicament capsules with gripping construction |
US5422160A (en) * | 1989-01-26 | 1995-06-06 | R. P. Scherer Corporation | Softgel capsule with a patterned outer shell surface |
WO1995017153A1 (fr) * | 1993-12-20 | 1995-06-29 | R.P. Scherer Corporation | Capsules de gelatine molle contenant une matiere particulaire |
WO1996019963A1 (fr) * | 1994-12-23 | 1996-07-04 | Basf Aktiengesellschaft | Procede de fabrication de comprimes enrobes |
EP0935958A1 (fr) * | 1998-02-17 | 1999-08-18 | SCA Lohnherstellungs AG | Cylindre de formage et méthode d'usinage des cylindres de formage |
US6352717B2 (en) | 1998-11-17 | 2002-03-05 | Hoffman-La Roche Inc. | Process for encapsulating shear sensitive fill masses into capsules and capsules containing shear sensitive fill masses |
WO2010108948A1 (fr) * | 2009-03-26 | 2010-09-30 | Swiss Caps Rechte Und Lizenzen Ag | Procédé et dispositif pour la fabrication de capsules molles |
US11541216B2 (en) | 2019-11-21 | 2023-01-03 | Massachusetts Institute Of Technology | Methods for manufacturing tissue interfacing components |
US11712421B2 (en) | 2017-05-17 | 2023-08-01 | Massachusetts Institute Of Technology | Self-actuating articles |
US12059562B2 (en) | 2018-05-17 | 2024-08-13 | Massachusetts Institute Of Technology | Systems for electrical stimulation |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DD75367A (fr) * | ||||
DE1185109B (de) * | 1962-02-05 | 1965-01-07 | Vitamins Ltd | Verfahren zur Herstellung nahtloser Kapseln und Vorrichtung zur Durchfuehrung dieses Verfahrens |
-
1985
- 1985-12-23 DE DE8536337U patent/DE8536337U1/de not_active Expired
-
1986
- 1986-12-19 DE DE8686117728T patent/DE3678119D1/de not_active Revoked
- 1986-12-19 EP EP86117728A patent/EP0227060B1/fr not_active Expired - Lifetime
- 1986-12-19 ES ES86117728T patent/ES2021275B3/es not_active Expired - Lifetime
- 1986-12-19 AT AT86117728T patent/ATE61521T1/de not_active IP Right Cessation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DD75367A (fr) * | ||||
DE1185109B (de) * | 1962-02-05 | 1965-01-07 | Vitamins Ltd | Verfahren zur Herstellung nahtloser Kapseln und Vorrichtung zur Durchfuehrung dieses Verfahrens |
Cited By (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5422160A (en) * | 1989-01-26 | 1995-06-06 | R. P. Scherer Corporation | Softgel capsule with a patterned outer shell surface |
US5246635A (en) * | 1989-01-26 | 1993-09-21 | R. P. Scherer Corporation | Method and apparatus for the manufacture of textured softgels |
US5380534A (en) * | 1992-08-18 | 1995-01-10 | R.P. Scherer Corporation | Soft gelatin medicament capsules with gripping construction |
WO1995017153A1 (fr) * | 1993-12-20 | 1995-06-29 | R.P. Scherer Corporation | Capsules de gelatine molle contenant une matiere particulaire |
AU686293B2 (en) * | 1993-12-20 | 1998-02-05 | R.P. Scherer Corporation | Soft gelatin capsules containing particulate material |
CN1113638C (zh) * | 1994-12-23 | 2003-07-09 | 巴斯福股份公司 | 包覆片剂的制造方法 |
WO1996019963A1 (fr) * | 1994-12-23 | 1996-07-04 | Basf Aktiengesellschaft | Procede de fabrication de comprimes enrobes |
AU696878B2 (en) * | 1994-12-23 | 1998-09-17 | Basf Aktiengesellschaft | The production of covered tablets |
EP0935958A1 (fr) * | 1998-02-17 | 1999-08-18 | SCA Lohnherstellungs AG | Cylindre de formage et méthode d'usinage des cylindres de formage |
US6352717B2 (en) | 1998-11-17 | 2002-03-05 | Hoffman-La Roche Inc. | Process for encapsulating shear sensitive fill masses into capsules and capsules containing shear sensitive fill masses |
AU751446B2 (en) * | 1998-11-17 | 2002-08-15 | F. Hoffmann-La Roche Ag | Process for the manufacture of liquid filled capsules |
WO2010108948A1 (fr) * | 2009-03-26 | 2010-09-30 | Swiss Caps Rechte Und Lizenzen Ag | Procédé et dispositif pour la fabrication de capsules molles |
US8727754B2 (en) | 2009-03-26 | 2014-05-20 | Swiss Caps Rechte Und Lizenzen Ag | Method and device for producing soft capsules |
US11712421B2 (en) | 2017-05-17 | 2023-08-01 | Massachusetts Institute Of Technology | Self-actuating articles |
US12064520B2 (en) | 2017-05-17 | 2024-08-20 | Massachusetts Institute Of Technology | Components with high API loading |
US12059562B2 (en) | 2018-05-17 | 2024-08-13 | Massachusetts Institute Of Technology | Systems for electrical stimulation |
US11541216B2 (en) | 2019-11-21 | 2023-01-03 | Massachusetts Institute Of Technology | Methods for manufacturing tissue interfacing components |
Also Published As
Publication number | Publication date |
---|---|
EP0227060A3 (en) | 1988-06-29 |
DE3678119D1 (de) | 1991-04-18 |
ES2021275B3 (es) | 1991-11-01 |
EP0227060B1 (fr) | 1991-03-13 |
ATE61521T1 (de) | 1991-03-15 |
DE8536337U1 (de) | 1986-02-13 |
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