EP0190254A1 - Kloniertes gen, verfahren zu dessen herstellung und seine verwendung - Google Patents

Kloniertes gen, verfahren zu dessen herstellung und seine verwendung

Info

Publication number
EP0190254A1
EP0190254A1 EP85903899A EP85903899A EP0190254A1 EP 0190254 A1 EP0190254 A1 EP 0190254A1 EP 85903899 A EP85903899 A EP 85903899A EP 85903899 A EP85903899 A EP 85903899A EP 0190254 A1 EP0190254 A1 EP 0190254A1
Authority
EP
European Patent Office
Prior art keywords
gly
glu
ala
protein
antigenic protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP85903899A
Other languages
English (en)
French (fr)
Other versions
EP0190254A4 (de
Inventor
David M. Anderson
Russell John Mccandliss
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genex Corp
Original Assignee
Genex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genex Corp filed Critical Genex Corp
Publication of EP0190254A1 publication Critical patent/EP0190254A1/de
Publication of EP0190254A4 publication Critical patent/EP0190254A4/de
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/455Eimeria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/40Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/61Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24041Use of virus, viral particle or viral elements as a vector
    • C12N2710/24043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24141Use of virus, viral particle or viral elements as a vector
    • C12N2710/24143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
EP19850903899 1984-07-05 1985-07-05 Kloniertes gen, verfahren zu dessen herstellung und seine verwendung. Ceased EP0190254A4 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US62781184A 1984-07-05 1984-07-05
US627811 1984-07-05
US74652085A 1985-06-19 1985-06-19
US746520 1985-06-19

Publications (2)

Publication Number Publication Date
EP0190254A1 true EP0190254A1 (de) 1986-08-13
EP0190254A4 EP0190254A4 (de) 1987-03-09

Family

ID=27090539

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19850903899 Ceased EP0190254A4 (de) 1984-07-05 1985-07-05 Kloniertes gen, verfahren zu dessen herstellung und seine verwendung.

Country Status (2)

Country Link
EP (1) EP0190254A4 (de)
WO (1) WO1986000528A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4874705A (en) * 1985-05-16 1989-10-17 Solvay & Cie, S.A. DNA encoding an antigenic protein derived from Eimeria tenella and vaccines for prevention of coccidiosis caused by Eimeria tenella
US5187080A (en) * 1984-06-05 1993-02-16 Solvay & Cie S.A. DNA encoding an antigenic protein derived from Eimeria tenella and vaccines for prevention of coccidiosis caused by Eimeria tenella
US4639372A (en) * 1984-06-29 1987-01-27 Merck & Co., Inc. Coccidiosis vaccine
US5279960A (en) * 1984-07-05 1994-01-18 Enzon Corp. 25 KD coccidial antigen of eimeria tenella
US5273901A (en) * 1984-07-05 1993-12-28 Enzon Corp. Genetically engineered coccidiosis sporozoite 21.5 Kb antigen, ac-6b
EP0231537B1 (de) * 1985-12-03 1992-03-11 Solvay Antigene Proteine und diese enthaltende Impfstoffe zur Verhütung von Kokzidiose
DE3752182T2 (de) * 1986-01-27 1998-08-06 Syntro Corp Abgeschwächte herpesviren, herpesviren, die eine für aminosäuresequenzen kodierende fremd-dns enthalten, sowie impfstoffe, die diese enthalten
US5310668A (en) * 1986-06-20 1994-05-10 Merck & Co., Inc. Varicella-zoster virus as a live recombinant vaccine
WO1988002022A1 (en) * 1986-09-22 1988-03-24 Commonwealth Scientific And Industrial Research Or Recombinant poxviruses
WO1988006629A1 (en) * 1987-03-06 1988-09-07 Synergen Incorporated Polypeptides useful in diagnosis of coccidia infection and recombinant-dna methods for manufacturing same
JP2531729B2 (ja) * 1987-03-27 1996-09-04 日本ゼオン株式会社 組み換えアビポックスウイルス
AU605567B2 (en) * 1987-03-11 1991-01-17 Nippon Zeon Co., Ltd. Recombinant avipoxvirus
DE10399032I1 (de) * 1987-08-28 2004-01-29 Health Research Inc Rekombinante Viren.
US5286639A (en) * 1987-09-16 1994-02-15 Nippon Zeon Co., Ltd. Recombinant avipoxvirus
CA1340203C (en) * 1987-09-16 1998-12-15 Noboru Yanagida Recombinant apivoxvirus
US5128284A (en) * 1987-10-23 1992-07-07 Allied-Signal Inc. Preparation of lanthanum chromite powders by sol-gel
GB8724885D0 (en) * 1987-10-23 1987-11-25 Binns M M Fowlpox virus promotors
FR2632863B2 (fr) * 1987-10-29 1990-08-31 Transgene Sa Virus du fowlpox recombinant et vaccins derives de ces virus
FR2622456B1 (fr) * 1987-10-29 1990-02-02 Transgene Sa Virus du fowlpox recombinant, vecteurs d'expression de proteines heterologues et vaccins pour la volaille derives de ce virus
NZ227597A (en) * 1988-01-15 1991-11-26 Merck & Co Inc Eimeria tenella group b immunogens and their production
US5824656A (en) * 1988-01-15 1998-10-20 Merck & Co., Inc. Recombinant and native group B eimeria tenella immunogens useful as coccidiosis vaccines
US4973551A (en) * 1988-01-15 1990-11-27 Merck & Co., Inc. Vector for the expression of fusion proteins and protein immunogens
ZA889230B (en) * 1988-02-12 1989-08-30 Us Agriculture Cloned genes coding for avian coccidiosis antigens which induce a cell-mediated immune response and method of producing the same
US5122471A (en) * 1988-02-12 1992-06-16 The United States Of America As Represented By The Secretary Of Agriculture Cloned genes coding for avian coccidiosis antigens which induce a cell-mediated immune response
US4863490A (en) * 1988-02-22 1989-09-05 Gte Laboratories Incorporated Titanium diboride-based composite articles with alumina dispersoids, having improved fracture toughness
US4889836A (en) * 1988-02-22 1989-12-26 Gte Laboratories Incorporated Titanium diboride-based composite articles with improved fracture toughness
ZA893740B (en) * 1988-06-03 1990-02-28 Hoffmann La Roche Recombinant coccidiosis vaccines
FR2632709B1 (fr) * 1988-06-10 1990-08-31 Frey Andre Dispositif de rehabilitation in situ de canalisations non visitables de l'interieur
US5631154A (en) * 1988-06-10 1997-05-20 Therion Biologics, Incorporated Self assembled, defective, non-self-propagating lentivirus particles
GB2220941B (en) * 1988-06-24 1991-09-11 Nat Res Dev Fowlpox virus non-essential regions
ZA894726B (en) * 1988-06-27 1990-03-28 Akzo Nv Coccidiosis vaccine
JPH03505970A (ja) * 1988-07-05 1991-12-26 ジェネックス・コーポレーション 遺伝子工学によるコクシジウム症ワクチン
US5093258A (en) * 1988-08-26 1992-03-03 Therion Biologics Corporation Recombinant fowlpox virus and recombination vector
US5252713A (en) * 1988-09-23 1993-10-12 Neorx Corporation Polymeric carriers for non-covalent drug conjugation
US6008342A (en) * 1991-07-12 1999-12-28 Roche Vitamins Inc. DNA encoding eimeria antigen
US5403581A (en) * 1991-07-12 1995-04-04 Hoffmann-La Roche Inc. Coccidiosis vaccines

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0135712A2 (de) * 1983-08-19 1985-04-03 American Cyanamid Company Gegen Sporozoiten von Eimeria Spp. reaktive monoklonale Antikörper und Antigene
EP0164176A2 (de) * 1984-06-05 1985-12-11 Solvay Antigenische Proteine, dieselben enthaltende Vakzine, schützende Antikörper dagegen für die Verhütung von durch Eimeria tenella verursachte Coccidiosis
EP0167443A2 (de) * 1984-06-29 1986-01-08 Merck & Co. Inc. Kokzidiosevakzin

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0135712A2 (de) * 1983-08-19 1985-04-03 American Cyanamid Company Gegen Sporozoiten von Eimeria Spp. reaktive monoklonale Antikörper und Antigene
EP0164176A2 (de) * 1984-06-05 1985-12-11 Solvay Antigenische Proteine, dieselben enthaltende Vakzine, schützende Antikörper dagegen für die Verhütung von durch Eimeria tenella verursachte Coccidiosis
EP0167443A2 (de) * 1984-06-29 1986-01-08 Merck & Co. Inc. Kokzidiosevakzin

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BIOLOGICAL ABSTRACTS / REVIEWS-REPORTS-MEETINGS, vol. 29, no. 90288; H.D. DANFORTH et al.: "Development of an avian coccidial antigen by recombinant DNA technology", & POULTRY SCIENCE (US) 1985, vol. 64, no. suppl. 1 p85 *
See also references of WO8600528A1 *

Also Published As

Publication number Publication date
EP0190254A4 (de) 1987-03-09
WO1986000528A1 (en) 1986-01-30

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 19860728

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Effective date: 19930801

RIN1 Information on inventor provided before grant (corrected)

Inventor name: MCCANDLISS, RUSSELL, JOHN

Inventor name: ANDERSON, DAVID, M.