EP0169871A1 - Lamines absorbants - Google Patents

Lamines absorbants

Info

Publication number
EP0169871A1
EP0169871A1 EP85900710A EP85900710A EP0169871A1 EP 0169871 A1 EP0169871 A1 EP 0169871A1 EP 85900710 A EP85900710 A EP 85900710A EP 85900710 A EP85900710 A EP 85900710A EP 0169871 A1 EP0169871 A1 EP 0169871A1
Authority
EP
European Patent Office
Prior art keywords
layer
absorbent
laminate
hydrophilic
peat moss
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP85900710A
Other languages
German (de)
English (en)
Inventor
Nigel John Brassington
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johnson and Johnson
Original Assignee
Johnson and Johnson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson and Johnson filed Critical Johnson and Johnson
Publication of EP0169871A1 publication Critical patent/EP0169871A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B5/00Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts
    • B32B5/02Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts characterised by structural features of a fibrous or filamentary layer
    • B32B5/06Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts characterised by structural features of a fibrous or filamentary layer characterised by a fibrous or filamentary layer mechanically connected, e.g. by needling to another layer, e.g. of fibres, of paper
    • AHUMAN NECESSITIES
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    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/15Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/51Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators characterised by the outer layers
    • A61F13/511Topsheet, i.e. the permeable cover or layer facing the skin
    • A61F13/51121Topsheet, i.e. the permeable cover or layer facing the skin characterised by the material
    • AHUMAN NECESSITIES
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    • A61F13/00Bandages or dressings; Absorbent pads
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    • A61F13/51Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators characterised by the outer layers
    • A61F13/511Topsheet, i.e. the permeable cover or layer facing the skin
    • A61F13/513Topsheet, i.e. the permeable cover or layer facing the skin characterised by its function or properties, e.g. stretchability, breathability, rewet, visual effect; having areas of different permeability
    • A61F13/51305Topsheet, i.e. the permeable cover or layer facing the skin characterised by its function or properties, e.g. stretchability, breathability, rewet, visual effect; having areas of different permeability having areas of different permeability
    • A61F13/51311Topsheet, i.e. the permeable cover or layer facing the skin characterised by its function or properties, e.g. stretchability, breathability, rewet, visual effect; having areas of different permeability having areas of different permeability the permeability gradient being in the vertical direction
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    • A61F13/539Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators characterised by the absorbing medium characterised by the connection of the absorbent layers with each other or with the outer layers
    • BPERFORMING OPERATIONS; TRANSPORTING
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    • B32B5/00Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts
    • B32B5/22Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts characterised by the presence of two or more layers which are next to each other and are fibrous, filamentary, formed of particles or foamed
    • B32B5/24Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts characterised by the presence of two or more layers which are next to each other and are fibrous, filamentary, formed of particles or foamed one layer being a fibrous or filamentary layer
    • B32B5/26Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts characterised by the presence of two or more layers which are next to each other and are fibrous, filamentary, formed of particles or foamed one layer being a fibrous or filamentary layer another layer next to it also being fibrous or filamentary
    • DTEXTILES; PAPER
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    • D04H1/425Cellulose series
    • D04H1/4258Regenerated cellulose series
    • DTEXTILES; PAPER
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    • D04H1/40Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/15Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/53Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators characterised by the absorbing medium
    • A61F13/539Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators characterised by the absorbing medium characterised by the connection of the absorbent layers with each other or with the outer layers
    • A61F2013/53966Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators characterised by the absorbing medium characterised by the connection of the absorbent layers with each other or with the outer layers by needling, sewing, blow-needling
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2262/00Composition or structural features of fibres which form a fibrous or filamentary layer or are present as additives
    • B32B2262/02Synthetic macromolecular fibres
    • B32B2262/0276Polyester fibres
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00Properties of the layers or laminate
    • B32B2307/70Other properties
    • B32B2307/728Hydrophilic
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00Properties of the layers or laminate
    • B32B2307/70Other properties
    • B32B2307/73Hydrophobic
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2555/00Personal care
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2555/00Personal care
    • B32B2555/02Diapers or napkins

Definitions

  • This invention relates to absorbent laminates, especi ⁇ ally for use as or in products for absorbing body fluids, such as diapers, incontinence pads, sanitary napkins, tampons and.wound dressings.
  • Characteristics which are desirable in most absorbent products are high absorbency (i.e. the capacity to absorb large quantities of fluid per unit weight of absorbent), and a high rate of fluid uptake. It is generally also desirable for the absorbent material to have a high degree of fluid retention, so that absorbed fluid is not readily released when the product is subjected to externally applied pressure.
  • the present invention provides absorbent laminates which not only possess the above described characteristics, but also the capacity to transfer fluid rapidly away from a layer which is initially wetted, into an adjacent layer, leaving the first layer substantially dry to the touch. This latter characteristic is especially desirable in incontinence aids, because it gives greatly increased user comfort.
  • an absorbent laminate comprising a fluid-permeable first layer formed of a hydrophobic fibrous material, an absorb- ent hydrophilic layer adjacent thereto, and a plurality of fibres extending from within the first layer into the hydrophilic layer.
  • hydrophilic is used to describe materials which are wetted by water, (i.e. materials which have contact angles with water less than 90° )
  • hydrophobic is used to describe materials which are not wetted by water (i.e. materials which have contact angles equal to or greater than 90°).
  • the fibres which extend between the two layers serve as wicks along which aqueous fluids may be carried from the first layer into the hydrophilic layer.
  • fluid- transferring wicks in absorbent products is not in itself new. For example, British Patent Specification No.
  • 983576 describes an absorbent body comprising a cellular sponge having numerous closely spaced hydrophilic fibres extending from at least one surface into the main body of the sponge, the hydrophilic fibres being uncoated by the material of the sponge and forming channels acting to wick fluids from the surface of the cellular sponge material into the main body thereof.
  • a principal object of the invention described in the above-mentioned specification is to allow hydrophobic sponges to be used as padding materials in surgical dressings, without their acting as barriers to the uptake of wound exudates.
  • the hydrophilic fibres pass completely through the sheet of sponge material, so 'that the fibres act to draw aqueous fluids from the wound-contacting side of the sponge sheet through to the opposite surface where they are absorbed, by an appropriate absorbent layer.
  • the wicks serve not to provide fluid paths through an otherwise water-repellant layer, but to enhance fluid transfer between two water-absorbent layers.
  • fibrous materials which may be used for the first layer and for the wicks extending into the adjacent layer are polyolefins such as polyethylene, polypropylene and polybutylene homopolymers and copolymers, vinyl polymers such as polyvinylchloride, polyamides such as nylon, and polyesters.
  • polyolefins such as polyethylene, polypropylene and polybutylene homopolymers and copolymers
  • vinyl polymers such as polyvinylchloride
  • polyamides such as nylon
  • polyesters polyesters.
  • the fibrous hydrophobic layer is in the form of a nonwoven fibrous fleece, which may, if desired, be pre-needled in order to increase its coherence.
  • Examples of materials which may be used to form the absorbent hydrophilic layer include swellable acrylate polymers, swellable cellulosic polymers (these two groups sometimes being referred to as “superabsorbents” or “super retention agents"), peat moss board, sphagnum, absorbent inorganic materials, fluff pulp, absorbent papers and hydrophilic foamed polymers such as hydro ⁇ philic polyurethane oams.
  • a material which is particu ⁇ larly preferred is a peat moss composite board such as that describedin British Patent Specification No. 2081320.
  • the wicks which extend from the first layer into the adjacent layer may be formed in a number of ways.
  • wicks may be formed, for example, by stitch bonding the two layers together.
  • the hydrophobic fibres of the first layer are themselves used to form the wicks by needling the hydrophobic fibrous layer to the adjacent hydrophilic layer.
  • Needling is a process known per se as a means of laminating fibrous webs, and generally involves passing barbed needles into and out of a fibrous web in a reciprocating motion. Fibres from within the web are caught on the barbs of the needles, and are either pushed forward with the forward movement of the needle, or drawn back with the reverse movement of the needle, or both, depending on the type of needle used.
  • the density of needling is chosen according to the strength and fluid transport properties which are desired in the resulting laminate.
  • a needling density which is not constant over the whole area of the laminate.
  • a higher density of needling may be employed at the edges of an absorbent pad according to the invention, since it is here that greatest resis ⁇ tance to delamination is most likely to be required.
  • it m ay be appropriate to needle a pad for use as a wound
  • the laminate may be needled on one or both faces of the ydrophilic layer, and the needles may penetrate the hydrophilic layer completely or just partially.
  • Strengthening can be provided by including within the laminate an extra layer comprising an inex- tensible or relatively inextensible web or net
  • a greatly preferred method is to include strengthening threads along the length (i.e. along the machine direction) of the laminate. These threads should be “furry", for example threads of the type called “Boucle”. The furry exterior of these threads can then become entangled within the needled wicks passing perpendicularly through the laminate. The result of providing such threads at 1 cm intervals is to more than double the force required to fracture peat moss board, thus rendering the laminate more suitable for use as incontinence pads.
  • needling although pre- ferred, is not the only means by which fibres from within the fibrous layer can be caused to form wicks in accordance with the invention.
  • wicks may be formed by means of very ine, high pressure water jets directed at one or both free faces of two super-imposed fibrous webs, as more fully described in United States Patent Specifications Nos. 2862251 and 3033721.
  • the absorbent capacity required of the laminate will, of course, depend on the end use to which it is to be put. Generally, however, it is preferred that both the hydrophilic layer and the hydrophobic layer are cap ⁇ able of absorbing more than 5 grams of water per gram of absorbent. More preferably, the absorbent capacities of the core layer and the facing layer are both greater than 8 grams of water/gram of absorbent, for example 10 or more grams of water/gram of absorbent.
  • the hydrophobic layer should preferably be extremely permeable to fluids, so as to allow passage of fluid under gravity at a rate of at least 10 ml of fluid/second/cm without surface puddling, and more preferably at greater than 20 ml/sec/cm 2, e.g. 30 ml/sec/cm2. This is especially desirable when the laminate is used as an incontinence pad, so that urine can be absorbed even at full flow.
  • the absorbent products according to the present invention will usually incorpor ⁇ ate further layers in addition to the two layers described above.
  • the hydrophilic layer will be sand ⁇ wiched between at least two further layers.
  • a fluid-repellant layer such as plastics sheeting.
  • both faces of the hydrophilic layer will be covered with an absorbent layer, which may be of the same or different materials as each other, and of the same or different thickness and/or weight.
  • the hydrophilic layer may have one face covered with a polyester fibre web, and the other face covered with a viscose fibre web.
  • a particularly advantageous product according to the invention comprises a central core of peat moss board, such as BISHOP (Trade Mark) board, sandwiched between webs of polyester fibre.
  • Peat moss board is known from British Patent Specification No. 2081320 to be highly absorbent, but it does have some disadvan- tages, such as lack of strength and friability. Also, it has a fairly high bulk rigidity as a result of calendering in its manufacture.
  • a needled laminate of peat moss board with non-woven polyester fibre webs is found to have high tensile strengths, even when wet, in both the machine and cross directions, especially when reinforced by Boucle threads as above described. More ⁇ over, the laminate is soft and conformable.
  • the polyester fibre webs are capable of absorbing fluids at extremely high rates, and such absorbed fluid is quickly transferred to the peat moss board by means of the wicks formed during the needling operation.
  • the polyester fibre webs are found to .dry out within a very short time (e.g. of the order of 1 minute) of being wetted.
  • the product is also found to have a highly delayed strike-through rate. It is believed that this is part due to the swelling of the peat moss board on wetting, such swelling serving to restrict the pores formed through the board by the needling operation, thereby preventing wicking through to the opposite face of the product from the face which is wetted.
  • Peat moss board has the additional advantage of being somewhat deodorant, which is of great value in certain absorbent products, particularly incontinence pads and sanitary napkins.
  • peat moss board is naturally friable and produces a substantial quantity of fines, the open fluffy nature of the outer polyester webs tends to trap any fines generated, without the need for any coverstock. This is especially so if the peat moss board is entirely enclosed by the polyester fibre web, as is preferred for incontin- ence pads.
  • the benefit of fully enclosing the peat moss board is largely aesthetic, but a secondary advantage is that damp or wet absorbent material is prevented from contacting the wearer's skin or clothing.
  • Such a fully enclosed structure may be formed by intermittently feeding sections of peat moss board onto a continuous web of polyester fibre, covering the peat moss board with a second continuous polyester fibre web, needling and then severing the resulting laminate between the sections of peat moss board.
  • coverstocks reduce the rate of fluid uptake, add considerably to the cost and can lead to abrasion. Where a high rate of fluid uptake is less critical, such as in sanitary napkins, a coverstock can be used to enhance the appearance of the product.
  • a laminate comprising peat moss board and a loose polyester fibre web are used in a wound dressing
  • a low adherence wound con- tacting surface such as a spun bound polyester fabric
  • peat moss board will be used in weights 2 2 of from lOOg/m to lkg/m , and preferably from 300 to 500g/m .
  • weights 2 2 of from lOOg/m to lkg/m , and preferably from 300 to 500g/m .
  • the actual weight used, and that of the hydrophobic fibrous layer, will depend on the end use to which the laminate is to be put.
  • the fleece has a surface which can contact well with any coverstock placed over it; the very light fleece is adequate to obscure the peat moss board and to trap any fines; the laminate is not too bulky, and is highly flexible and conformable; the thin polyester fleece has very rapid surface drying properties (the surface being dry to the touch within a few seconds of being wetted) .
  • This construction has the following advantages: The total absorbency is appropriate to the needs of patients with stress or other forms of light voiding in ⁇ continence; the surface is coherent and does not require a coverstock; the fleeces are thick enough to hold con ⁇ siderable quantities of fluid in the short time before it is fully absorbed by the peat moss board; the thicker fleeces also give a high degree of cushioning.
  • Figure 1 is a plan view of an absorbent laminate according to the invention.
  • Figure 2 is a schematic section on line A-A of Figure 1, and
  • FIG 3 is a schematic section through an alternative absorbent laminate.
  • an absorbent laminate comprises a core layer 1, sandwiched between two facing layers 3, 5.
  • the core layer 1 is a
  • the facing layers 3, 5 are both non-woven pre-needled polyester fibre fleeces of weight 250g/m 2 , (Cosmopolitan Textiles Ltd., Winsford,
  • Each of the facing layers overlaps all four sides of the core layer, so that the latter is entirely enclosed and is surrounded by an edge region 7.
  • the three layers 1, 3, 5 are joined by needling at
  • 2 region 7 is needled at a density of 12 needles/cm , to form a strong bond between the peripheral areas of the facing layers.
  • Figure 3 illustrates a laminate which is analogous to that of Fibres 1 and 2, but differs in that two core layers of peat moss board 1, 2 are provided, with three facing layers 3, 4, 5 of polyester fibre web.
  • a three layer laminate is formed from the following materials :
  • a laminate was prepared as described in Example 1,
  • the laminate was sandwiched between two transparent PERSPEX (Trade Mark) plates, the lower of which was provided with a hole for the application of test fluid to the laminate under a small (e.g. 0.5 cm) hydrostatic head.
  • the strike-through time of the laminate was the time taken for such applied fluid to contact the upper PERSPEX plate, as detected by the specular appearance of the latter when first wetted.
  • Example 3 This example shows the effects of different needle densities on absorbency and other properties of the laminate.
  • polyester fibre used in the above Examples was a surface-treated polyethylene terephthalate (ICI type 578).
  • the surface- reatment was with a mixture of oleyl cetyl alcohol and castor oil ethylene oxide condensates with sodium benzoate, potassium hexyl phosphate and propanol.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Textile Engineering (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Mechanical Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Laminated Bodies (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Laminés absorbants, pouvant être utilisés en tant que couches, serviettes hygiéniques ou contre l'incontinence, tampons ou pansements, ou dans ces articles, comprenant une couche hydrophile (1) adjacente à une bande fibreuse perméable à l'eau (3). Des mèches transportant les fluides s'étendent depuis l'intérieur de la bande fibreuse jusque dans la couche hydrophile, et sont formées de préférence par aiguilletage. La couche hydrophile se compose de préférence d'une plaque composite en mousse de tourbe et la bande fibreuse est de préférence une couche de voile en polyester non tissé.
EP85900710A 1984-01-26 1985-01-28 Lamines absorbants Withdrawn EP0169871A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848402095A GB8402095D0 (en) 1984-01-26 1984-01-26 Absorbent laminates
GB8402095 1984-01-26

Publications (1)

Publication Number Publication Date
EP0169871A1 true EP0169871A1 (fr) 1986-02-05

Family

ID=10555592

Family Applications (2)

Application Number Title Priority Date Filing Date
EP85300569A Expired EP0151018B1 (fr) 1984-01-26 1985-01-28 Feuille absorbante laminée
EP85900710A Withdrawn EP0169871A1 (fr) 1984-01-26 1985-01-28 Lamines absorbants

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP85300569A Expired EP0151018B1 (fr) 1984-01-26 1985-01-28 Feuille absorbante laminée

Country Status (16)

Country Link
EP (2) EP0151018B1 (fr)
JP (1) JPS61501009A (fr)
AT (1) ATE41599T1 (fr)
AU (1) AU576553B2 (fr)
BR (1) BR8504532A (fr)
CA (1) CA1263224A (fr)
DE (1) DE3568940D1 (fr)
ES (1) ES8604811A1 (fr)
GB (1) GB8402095D0 (fr)
HK (1) HK36690A (fr)
IE (1) IE56426B1 (fr)
NZ (1) NZ210974A (fr)
PT (1) PT79882B (fr)
SG (1) SG78388G (fr)
WO (1) WO1985003218A1 (fr)
ZA (1) ZA85557B (fr)

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Also Published As

Publication number Publication date
IE56426B1 (en) 1991-07-31
HK36690A (en) 1990-05-18
WO1985003218A1 (fr) 1985-08-01
DE3568940D1 (en) 1989-04-27
IE850167L (en) 1985-07-26
GB8402095D0 (en) 1984-02-29
NZ210974A (en) 1988-02-29
EP0151018A3 (en) 1985-08-21
AU3888085A (en) 1985-08-09
EP0151018B1 (fr) 1989-03-22
JPS61501009A (ja) 1986-05-22
CA1263224A (fr) 1989-11-28
PT79882B (en) 1986-11-20
PT79882A (en) 1985-02-01
ZA85557B (en) 1986-08-27
EP0151018A2 (fr) 1985-08-07
ES8604811A1 (es) 1986-03-01
ES539870A0 (es) 1986-03-01
AU576553B2 (en) 1988-09-01
SG78388G (en) 1989-03-23
ATE41599T1 (de) 1989-04-15
BR8504532A (pt) 1985-12-24

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