EP0118975A1 - Feuille pour emballage blister - Google Patents

Feuille pour emballage blister Download PDF

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Publication number
EP0118975A1
EP0118975A1 EP84300418A EP84300418A EP0118975A1 EP 0118975 A1 EP0118975 A1 EP 0118975A1 EP 84300418 A EP84300418 A EP 84300418A EP 84300418 A EP84300418 A EP 84300418A EP 0118975 A1 EP0118975 A1 EP 0118975A1
Authority
EP
European Patent Office
Prior art keywords
sheet
blister
blister sheet
thermoplastic polymer
cavities
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP84300418A
Other languages
German (de)
English (en)
Inventor
Gerhard Thomas Schwartz
Bruce Reynolds Inglis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wiggins Teape Group Ltd
Original Assignee
Wiggins Teape Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wiggins Teape Group Ltd filed Critical Wiggins Teape Group Ltd
Publication of EP0118975A1 publication Critical patent/EP0118975A1/fr
Withdrawn legal-status Critical Current

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/04Articles or materials wholly enclosed in single sheets or wrapper blanks
    • B65D75/20Articles or materials wholly enclosed in single sheets or wrapper blanks in sheets or blanks doubled around contents and having their opposed free margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/22Articles or materials wholly enclosed in single sheets or wrapper blanks in sheets or blanks doubled around contents and having their opposed free margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding the sheet or blank being recessed to accommodate contents
    • B65D75/24Articles or materials wholly enclosed in single sheets or wrapper blanks in sheets or blanks doubled around contents and having their opposed free margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding the sheet or blank being recessed to accommodate contents and formed with several recesses to accommodate a series of articles or quantities of material
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/325Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
    • B65D75/327Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming several compartments

Definitions

  • This invention relates to a blister sheet which is particularly applicable for packaging medicines in the form of capsules, tablets and the like.
  • This type of sheet may, however, also be used when packing other articles which need to be sealed separately prior to use such as metal articles which are susceptible to corrosion.
  • Another known sheet of this type is a blister sheet which consists of a polyvinyl chloride sheet which has been formed by heat and pressure into blisters.
  • the articles to be packed are then placed in the blisters and a lidding sheet of aluminium foil applied over the flat surface of the blister sheet to seal the blisters.
  • the lidding sheet is sealed to the blister sheet to form a pack by various means, for example a hot melt adhesive in a heat sealing process. Because of the nature of the pack and the manufacturing process, it is only practicable to manufacture such packs under factory conditions. As a result, the product is limited to the packaging of standard packs, for example aspirin tablets.
  • a blister sheet for use in a blister pack comprises a paper sheet which has been thermoformed to provide one or more blister cavities to receive articles to be packaged, said sheet being made from a blend of cellulosic and/or staple fibres with thermoplastic polymer at least a portion or all of said thermoplastic polymer being fibrillated.
  • thermoplastic polymer in the form of fibrillated fibres are those sold under the trade name SWP by Crown-Zellerbach Corporation and the trade name PULPEX L4 by Solvay et Cie.
  • thermoplastic polymer Preferably between 80% and 90% of the thermoplastic polymer is fibrillated.
  • the exact proportion of fibrillated thermoplastic polymer desirable in the paper sheet will vary with the depth and configuration of the blister cavities to be formed.
  • thermoplastic polymer content is between 60% and 95% of the blend.
  • thermoplastic polymer content is preferably at least 75% and where high translucency is required about 85% of the blend.
  • the sheet may also include coloured or white pigments such as titanium dioxide to confer opacity and resistance to ultra violet light.
  • coloured or white pigments such as titanium dioxide to confer opacity and resistance to ultra violet light.
  • the titanium dioxide content should not exceed 20% and for such a proportion of the loading, the thermoplastic polymer content should not be less than 75%
  • the fibrillated thermoplastic polymer material may, for example, be constituted by a polyolefin such as polyethylene or polypropylene.
  • Particulate thermoplastic polymer material may be included to supplement the fibrillated thermoplastic polymer material.
  • cellulosic and staple fibres which may be used are bleached or unbleached softwood and hardwood sulphite and sulphate pulps, cotton linters and rayon and polyester staple fibres. Of these hardwood sulphate pulp is especially preferred as conferring good thermoformability whilst providing low permeability in the thermoformed sheet.
  • lidding for the blister sheet conventional aluminium foil may be used or a paper lidding may be provided. Papers such as glassine, greaseproof, tracing or vegetable parchment, which have high burst and low tear resistance characteristics are also appropriate for use as lidding materials.
  • the paper lidding may also comprise a mixture of thermplastic material and cellulose fibres in a ratio of, for example 75% thermoplastic to 25% cellulose.
  • the blister sheet may be as set forth above and be formed with a fold line so as to divide it into first and second portions, said first portion having blister cavities formed therein for receiving articles to be packaged so that when articles are located in said cavities the second portion can be folded along said fold line to provide a lidding sheet which can be adhered to said first portion to form a blister pack separately enclosing said articles.
  • the said second portion may also be provided with blister cavities which are spaced on said sheet to coincide with said blister cavities on said first portion when the sheet is folded.
  • Adhesion is preferably achieved by means of a high tack dry latex adhesive which coats sufficient of the planar surfaces of the sheet to ensure that after a lidding sheet has been applied the blisters are isolated from each other and the atmosphere. A layer of such adhesive will only adhere to another layer of the same adhseive, thus obviating the need to provide protective release sheets.
  • the high tack dry latex adhesive may be substituted by other self-adhesives, in which case release sheets, coated for example with silicone release coatings, will be applied to the adhesive coatings as a protection. These release sheets will have apertures which coincide with the moulded recesses of the sheet so that only areas coated with adhcsive will be covered by the release sheet. The release sheets will then be stripped off before the sheet is used to form a blister pack. This pack does not require any machinery or factory conditions for assembly and may be easily used by the pharmacist when packing prescribed medicines in his shop.
  • the self-adhesives used may be of any well known kind. Commonly such adhesives are based on natural rubber, styrene butadiene rubber, butyl rubber or polyisobutene as backbone polymers modified with suitable tackifiers and plasticizers.
  • thermoplastic content of the sheet of the invention also renders it heat sealable to an appropriate lidding without the use of an adhesive.
  • special heat sealing machinery is required in both cases and this sealing method would not therefore be suitable for use by the pharmacist.
  • Adhesive may be applied as appropriate to facilitate adhesion.
  • the invention is not limited to the use of any particular adhesives and the foregoing merely constitute examples of types of adhesive which may be used.
  • the blister pack may also be provided without adhesive thus allowing the pharmacist to apply his own as necessary,
  • the sheet used may also incorporate a metal layer provided by vacuum deposition and will generally be of aluminium.
  • an ultra violet absorber such as titanium dioxide either in the body of the sheet or as a coating can be included. Titanium dioxide also confers opacity on the sheet. Opacity may also be provided by the use of other coatings, for example, white or tinted inks.
  • the sheet could also be provided with detachment means in the form of perforations which extend between the sealed blisters so that the patient is able to easily detach each dose in a separate blister.
  • detachment means in the form of perforations which extend between the sealed blisters so that the patient is able to easily detach each dose in a separate blister.
  • weakened lines could be provided by thermoforming or mechanical composition.
  • the invention further comprises a blister pack formed using blister sheets as above referred to.
  • a blister sheet 1 is made from a mixture of cellulosic and fibrillated synthetic thermoplastic fibres.
  • the synthetic fibres used are those sold under the Trade name SWP by Crown Zellerbach Corporation.
  • the proportion of fibrillated thermoplastic polymer desirable in the paper sheet will vary with the depth and configuration of the blister cavities to be formed.
  • the thermoplastic polymer therefore is between 75% and 80% and is made up from approximately 75% fibrillated fibres and 25% particulate material.
  • the remainder of the blend comprises the cellulosic and staple fibre material and this can be hardwood sulphate pulp,
  • pigment such as titanium dioxide is also included.
  • An alternative blend of materials suitable for the construction shown in Figures 1 and 2 comprises a blend of synthetic thermoplastic fibre material of the kind sold under the trade name PULPEX EA by Solvay et Cie.
  • high translucency is achieved by including thermoplastic polymer amounting to about 85% of the blend, the remainder again being hardwood sulphate pulp.
  • thermoplastic polymer amounting to about 85% of the blend, the remainder again being hardwood sulphate pulp.
  • at least 60% of the thermoplastic polymer is in fibrillated form, the remainder being particulate.
  • the sheet may be formed on a conventional papermaking machine and when it it to be made up into a blister sheet it is moulded by thermal deformation to provide blisters 2.
  • the blister sheet 1 has coated thereon a layer of high tack dry latex adhesive 3 and contains within its blisters 3 drug tablets 4.
  • a lidding sheet 5 carries thereon a layer 6 of the same high tack dry latex adhesive.
  • the adhesive layers 3 and 6 are mutually adhesive but will not adhere to any other surface. They are sealed together at the locations 7 between the blisters so that each tablet 4 is isolated.
  • the lidding sheet 5 is made of paper, and preferably of a paper having high burst and low tear resistance characteristics. This ensures that inadvertent rupture of the lidding sheet is minimised whilst ensuring that after intentional rupture, it will tear easily to release a selected tablet.
  • Such papers are exemplified by glassine, greaseproof, tracing and vegetable parchment papers, burst and tear characteristics for which are set out in the following table :
  • FIG 3 shows a modification of the embodiment of Figures 1 and 2 particularly suited for packing articles 10 which are susceptible to ultra violet and/or hygroscopic degeneration.
  • the construction and assembly of the blister pack is generally as described above with reference to Figures 1 and 2 and where appropriate, the various parts are designated by the same reference numerals.
  • the outer surfaces of the blister and lidding sheets 1 and 5 are provided with metal layers in 11 and 12 respectively.
  • the metal layers are provided by vacuum deposition, for example of aluminium.
  • the provision of a metal layer has a further advantage in that it renders both the blister pack and lidding sheet opaque and thus conceals the contents from children who might otherwise identify them as sweets or candies.
  • a sheet 21 which may optionally carry printed materials and is made from a blend of cellulose and synthetic fibres together with suitable known binders.
  • the sheet 21 is also coated with a cold seal adhesive 24.
  • the sheet is moulded, for example by thermal deformation to provide blisters 22, being divided into first and second portions by a fold line 23.
  • Capsules or the like 25 are placed in the blisters so that when the sheet is folded about the fold line 23 as indicated by the arrow X the second portion acts as a lidding sheet and the capsules become sealed in a blister.
  • Information such as names, dates or dosage may be manually applied on the flat surface 26 at this stage.
  • the sheet 21 has blisters 22 spaced from either side of the fold line 23 so that on folding as indicated by the arrow X, the recessed areas in one portion,coincide with the blisters in the other portion.
  • FIG-7 the sheet 21 of the second embodiment is shown after folding along fold line 23 in direction X.
  • sealing is effected by the cold seal adhesive 24, and the second portion again acting as a lidding sheet.
  • the sheet 21 has been provided with a metal surface layer 27 by vacuum metallization. Apart from this the construction is the same as that shown in Figure 5 and is particularly suitable for packing articles which are susceptible to hygroscopic or ultraviolet degradation.
  • This metal layer is provided by vacuum deposition of aluminium after the sheet has been formed.
EP84300418A 1983-02-09 1984-01-24 Feuille pour emballage blister Withdrawn EP0118975A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8303600 1983-02-09
GB838303600A GB8303600D0 (en) 1983-02-09 1983-02-09 Blister sheet

Publications (1)

Publication Number Publication Date
EP0118975A1 true EP0118975A1 (fr) 1984-09-19

Family

ID=10537727

Family Applications (1)

Application Number Title Priority Date Filing Date
EP84300418A Withdrawn EP0118975A1 (fr) 1983-02-09 1984-01-24 Feuille pour emballage blister

Country Status (3)

Country Link
EP (1) EP0118975A1 (fr)
GB (1) GB8303600D0 (fr)
ZA (1) ZA84846B (fr)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2174070A (en) * 1985-04-15 1986-10-29 Boxall Company Blister packs
EP0354709A2 (fr) * 1988-08-12 1990-02-14 Minnesota Mining And Manufacturing Company Ruban pour enfermer des composants électroniques
EP0703157A1 (fr) * 1994-08-23 1996-03-27 Alusuisse-Lonza Services AG Emballage du type blister
DE19603268A1 (de) * 1996-01-30 1997-07-31 Riedel Manfred Dipl Ing Fh Elektrisch leitfähige Montage-Verpackungen für elektonische Bauteile (SMD-Verpackungen bzw. Blistergurte)
EP1201560A1 (fr) * 1999-07-29 2002-05-02 Matsushita Electric Industrial Co., Ltd. Bloc-piles
WO2004043823A1 (fr) * 2002-11-11 2004-05-27 Wright, Fenn & Co. Ltd. Plaquette alveolaire
WO2005093876A1 (fr) * 2004-02-27 2005-10-06 Eveready Battery Company, Inc. Bloc-batteries modulaire
US7854225B2 (en) 2002-11-02 2010-12-21 Glaxo Group Limited Blister package for inhalable medicament
WO2014179293A1 (fr) * 2013-04-29 2014-11-06 Keene Building Products Co., Inc. Structure d'empaquetage d'un réseau de filaments tridimensionnel

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH234004A (de) * 1941-07-03 1944-08-31 Gmbh Papierfabrik Guenzach Verpackungsmaterial für stark fetthaltige Nahrungsmittel.
US3202277A (en) * 1964-03-19 1965-08-24 Lewi William Dual seal package
US3630346A (en) * 1970-06-01 1971-12-28 Lilly Co Eli Components for making a strip package
DE2208554A1 (de) * 1971-03-03 1972-09-14 Crown Zellerbach Corp Folie sowie Verfahren zu ihrer Herstellung
US4083451A (en) * 1972-09-14 1978-04-11 Hair George R Method of heat sealing sheet-form layers of perforated plastic between layers of paperboard
EP0015338A1 (fr) * 1979-02-28 1980-09-17 Gulf Oil Corporation Un procédé pour améliorer la résistance à la traction de feuilles de papier cellulosiques préparées par voie humide et une feuille de papier cellulosique ainsi préparée par voie humide
DE3029253A1 (de) * 1980-08-01 1982-03-11 Dixie-Union Verpackungen Gmbh, 8960 Kempten Kindersichere arzneimittelverpackung

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH234004A (de) * 1941-07-03 1944-08-31 Gmbh Papierfabrik Guenzach Verpackungsmaterial für stark fetthaltige Nahrungsmittel.
US3202277A (en) * 1964-03-19 1965-08-24 Lewi William Dual seal package
US3630346A (en) * 1970-06-01 1971-12-28 Lilly Co Eli Components for making a strip package
DE2208554A1 (de) * 1971-03-03 1972-09-14 Crown Zellerbach Corp Folie sowie Verfahren zu ihrer Herstellung
US4083451A (en) * 1972-09-14 1978-04-11 Hair George R Method of heat sealing sheet-form layers of perforated plastic between layers of paperboard
EP0015338A1 (fr) * 1979-02-28 1980-09-17 Gulf Oil Corporation Un procédé pour améliorer la résistance à la traction de feuilles de papier cellulosiques préparées par voie humide et une feuille de papier cellulosique ainsi préparée par voie humide
DE3029253A1 (de) * 1980-08-01 1982-03-11 Dixie-Union Verpackungen Gmbh, 8960 Kempten Kindersichere arzneimittelverpackung

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2174070A (en) * 1985-04-15 1986-10-29 Boxall Company Blister packs
EP0354709A2 (fr) * 1988-08-12 1990-02-14 Minnesota Mining And Manufacturing Company Ruban pour enfermer des composants électroniques
EP0354709A3 (en) * 1988-08-12 1990-11-14 Minnesota Mining And Manufacturing Company A tape for encasing electronic parts
CH689305A5 (de) * 1994-08-23 1999-02-15 Alusuisse Lonza Services Ag Blisterpackung.
AU693573B2 (en) * 1994-08-23 1998-07-02 Alusuisse Technology & Management Ltd. Blister pack
EP0703157A1 (fr) * 1994-08-23 1996-03-27 Alusuisse-Lonza Services AG Emballage du type blister
DE19603268A1 (de) * 1996-01-30 1997-07-31 Riedel Manfred Dipl Ing Fh Elektrisch leitfähige Montage-Verpackungen für elektonische Bauteile (SMD-Verpackungen bzw. Blistergurte)
EP1201560A1 (fr) * 1999-07-29 2002-05-02 Matsushita Electric Industrial Co., Ltd. Bloc-piles
EP1201560A4 (fr) * 1999-07-29 2005-07-20 Matsushita Electric Ind Co Ltd Bloc-piles
US7854225B2 (en) 2002-11-02 2010-12-21 Glaxo Group Limited Blister package for inhalable medicament
WO2004043823A1 (fr) * 2002-11-11 2004-05-27 Wright, Fenn & Co. Ltd. Plaquette alveolaire
WO2005093876A1 (fr) * 2004-02-27 2005-10-06 Eveready Battery Company, Inc. Bloc-batteries modulaire
US7780009B2 (en) 2004-02-27 2010-08-24 Eveready Battery Company, Inc. Modular battery package
WO2014179293A1 (fr) * 2013-04-29 2014-11-06 Keene Building Products Co., Inc. Structure d'empaquetage d'un réseau de filaments tridimensionnel

Also Published As

Publication number Publication date
ZA84846B (en) 1984-09-26
GB8303600D0 (en) 1983-03-16

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Designated state(s): BE DE FR GB IT LU NL

17P Request for examination filed

Effective date: 19840929

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19851014

RIN1 Information on inventor provided before grant (corrected)

Inventor name: INGLIS, BRUCE REYNOLDS

Inventor name: SCHWARTZ, GERHARD THOMAS