EG24851A - Crystalline anticholinergic process for the preparation thereof for preparing a medicament - Google Patents

Crystalline anticholinergic process for the preparation thereof for preparing a medicament

Info

Publication number
EG24851A
EG24851A EG2002060698A EG2002060698A EG24851A EG 24851 A EG24851 A EG 24851A EG 2002060698 A EG2002060698 A EG 2002060698A EG 2002060698 A EG2002060698 A EG 2002060698A EG 24851 A EG24851 A EG 24851A
Authority
EG
Egypt
Prior art keywords
medicament
preparing
preparation
anticholinergic
crystalline
Prior art date
Application number
EG2002060698A
Other languages
English (en)
Inventor
Peter Sieger
Ulrike Werthmann
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Application granted granted Critical
Publication of EG24851A publication Critical patent/EG24851A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
EG2002060698A 2001-06-22 2002-06-19 Crystalline anticholinergic process for the preparation thereof for preparing a medicament EG24851A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10129710 2001-06-22
DE10215436 2002-04-08

Publications (1)

Publication Number Publication Date
EG24851A true EG24851A (en) 2010-10-27

Family

ID=26009556

Family Applications (1)

Application Number Title Priority Date Filing Date
EG2002060698A EG24851A (en) 2001-06-22 2002-06-19 Crystalline anticholinergic process for the preparation thereof for preparing a medicament

Country Status (38)

Country Link
EP (1) EP1401445B1 (fr)
JP (1) JP2005504015A (fr)
KR (2) KR100971616B1 (fr)
CN (1) CN100586948C (fr)
AR (1) AR037491A1 (fr)
AT (1) ATE337006T1 (fr)
AU (1) AU2002345016B2 (fr)
BG (1) BG66303B1 (fr)
BR (1) BR0210537A (fr)
CA (1) CA2450961C (fr)
CO (1) CO5550423A2 (fr)
CY (1) CY1105223T1 (fr)
CZ (1) CZ302786B6 (fr)
DE (1) DE50207943D1 (fr)
DK (1) DK1401445T3 (fr)
EA (1) EA005813B1 (fr)
EE (1) EE05316B1 (fr)
EG (1) EG24851A (fr)
ES (1) ES2271280T3 (fr)
HK (1) HK1068540A1 (fr)
HR (1) HRP20031066B1 (fr)
HU (1) HUP0400333A3 (fr)
IL (2) IL159238A0 (fr)
ME (1) ME00412B (fr)
MX (1) MXPA03011718A (fr)
MY (1) MY122779A (fr)
NO (1) NO334301B1 (fr)
NZ (1) NZ530690A (fr)
PE (2) PE20030130A1 (fr)
PL (1) PL208137B1 (fr)
PT (1) PT1401445E (fr)
RS (1) RS50441B (fr)
SA (1) SA02230255B1 (fr)
SI (1) SI1401445T1 (fr)
SK (1) SK287262B6 (fr)
TW (2) TW200617007A (fr)
UY (1) UY27342A1 (fr)
WO (1) WO2003000265A1 (fr)

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JP5270343B2 (ja) 2005-08-15 2013-08-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ベータミメティックスの製造方法
TWI396541B (zh) 2005-10-10 2013-05-21 Boehringer Ingelheim Int 用於治療呼吸疾病之新穎藥物組合
US7423146B2 (en) 2005-11-09 2008-09-09 Boehringer Ingelheim International Gmbh Process for the manufacturing of pharmaceutically active 3,1-benzoxazine-2-ones
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CN100999521B (zh) * 2006-01-13 2010-12-08 江苏正大天晴药业股份有限公司 结晶性抗胆碱药噻托溴铵
EP1847543A1 (fr) 2006-04-19 2007-10-24 Boehringer Ingelheim Pharma GmbH & Co. KG Dihydrothienopyrimidines pour le traitement de maladies inflammatoires
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EA020548B1 (ru) 2008-12-19 2014-12-30 Бёрингер Ингельхайм Интернациональ Гмбх Циклические пиримидин-4-карбоксамиды в качестве антагонистов рецептора ccr2, предназначенные для лечения воспаления, астмы и хозл
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JP2013526507A (ja) 2010-05-12 2013-06-24 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規ｃｃｒ２受容体アンタゴニスト、その製造方法及び薬物としてのその使用
US8841313B2 (en) 2010-05-17 2014-09-23 Boehringer Ingelheim International Gmbh CCR2 antagonists and uses thereof
EP2576542B1 (fr) 2010-05-25 2015-04-22 Boehringer Ingelheim International GmbH Dérivés d'amide cycliques d'acides pyridazine-3-carboxyliques utiles dans le traitement de maladies respiratoires, liées à des douleurs, liées au système immunitaire et cardiovasculaires
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TR201007108A2 (tr) * 2010-08-25 2012-03-21 B�Lg�� Mahmut Yeni tiotropyum bromür kristali ve üretim yöntemi.@
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TR201101897A2 (tr) 2011-02-28 2012-09-21 Bi̇lgi̇ç Mahmut Tiotropyum bromür içeren kristal madde
TR201102068A2 (tr) 2011-03-03 2012-09-21 Bi̇lgi̇ç Mahmut Tiotropyum bromür içeren kristal maddeler
TR201111589A2 (tr) * 2011-03-03 2012-09-21 Bi̇lgi̇ç Mahmut Tiotropyum bromür susuz kristal formu.
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JP5786258B2 (ja) 2011-07-15 2015-09-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規かつ選択的なｃｃｒ２拮抗薬
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ES2864009T3 (es) 2011-11-25 2021-10-13 Adverio Pharma Gmbh 5-Fluoro-1H-pirazolopiridinas sustituidas en forma cristalina
CZ304368B6 (cs) 2011-11-28 2014-04-02 Zentiva, K.S. Směsný solvát tiotropium bromidu a způsob jeho přípravy
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EP2897955B1 (fr) * 2012-09-11 2019-11-06 Bilgic, Mahmut Nouvelle forme cristalline du bromure de tiotropium
ME02679B (fr) 2012-11-05 2017-06-20 Zentiva Ks Stabilisation de solvates de tiotropium
CN104341412A (zh) * 2013-07-29 2015-02-11 天津金耀集团有限公司 一种无水噻托溴铵结晶的制备方法
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KR102331856B1 (ko) 2014-10-21 2021-11-29 다케다 야쿠힌 고교 가부시키가이샤 결정 형태의 5-클로로-n4-[2-(디메틸포스포릴)페닐]-n2-｛2-메톡시-4-[4-(4-메틸피페라진-1-일)피페리딘-1-일]피리미딘-2,4-디아민
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Also Published As

Publication number Publication date
PE20030130A1 (es) 2003-04-02
AR037491A1 (es) 2004-11-17
MXPA03011718A (es) 2004-12-06
PE20081305A1 (es) 2008-10-01
BG66303B1 (bg) 2013-03-29
SK522004A3 (en) 2004-06-08
HK1068540A1 (en) 2005-04-29
EP1401445A1 (fr) 2004-03-31
EE200400029A (et) 2004-04-15
HRP20031066A2 (en) 2004-04-30
KR100971616B1 (ko) 2010-07-22
DK1401445T3 (da) 2006-11-27
ES2271280T3 (es) 2007-04-16
TW200617007A (en) 2006-06-01
RS50441B (sr) 2010-03-02
KR101011353B1 (ko) 2011-01-28
SK287262B6 (sk) 2010-04-07
EA005813B1 (ru) 2005-06-30
MEP62008A (en) 2011-05-10
UY27342A1 (es) 2003-02-28
CO5550423A2 (es) 2005-08-31
KR20090031638A (ko) 2009-03-26
PL208137B1 (pl) 2011-03-31
YU99703A (sh) 2006-05-25
NZ530690A (en) 2005-05-27
KR20040018285A (ko) 2004-03-02
HRP20031066B1 (en) 2011-10-31
DE50207943D1 (de) 2006-10-05
TWI261589B (en) 2006-09-11
AU2002345016B2 (en) 2008-04-17
EA200301293A1 (ru) 2004-08-26
EP1401445B1 (fr) 2006-08-23
CN100586948C (zh) 2010-02-03
SI1401445T1 (sl) 2007-02-28
SA02230255B1 (ar) 2006-10-31
BR0210537A (pt) 2004-06-22
BG108440A (en) 2004-08-31
CA2450961C (fr) 2010-03-30
WO2003000265A1 (fr) 2003-01-03
EE05316B1 (et) 2010-08-16
CZ2004120A3 (cs) 2004-05-12
ATE337006T1 (de) 2006-09-15
HUP0400333A2 (hu) 2004-12-28
IL159238A (en) 2010-04-15
IL159238A0 (en) 2004-06-01
ME00412B (fr) 2011-10-10
PT1401445E (pt) 2006-10-31
CA2450961A1 (fr) 2003-01-03
NO20035696D0 (no) 2003-12-19
HUP0400333A3 (en) 2012-10-29
MY122779A (en) 2006-05-31
JP2005504015A (ja) 2005-02-10
CZ302786B6 (cs) 2011-11-09
PL364489A1 (en) 2004-12-13
CN1520294A (zh) 2004-08-11
NO334301B1 (no) 2014-02-03
CY1105223T1 (el) 2010-03-03

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