EG20726A - Process for preparing of galanthamine derivatives as acetylchol inc-sterase inhibitors - Google Patents
Process for preparing of galanthamine derivatives as acetylchol inc-sterase inhibitorsInfo
- Publication number
- EG20726A EG20726A EG64694A EG64694A EG20726A EG 20726 A EG20726 A EG 20726A EG 64694 A EG64694 A EG 64694A EG 64694 A EG64694 A EG 64694A EG 20726 A EG20726 A EG 20726A
- Authority
- EG
- Egypt
- Prior art keywords
- acetylchol
- preparing
- compounds
- galanthamine derivatives
- sterase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/137,444 US6316439B1 (en) | 1993-10-15 | 1993-10-15 | Galanthamine derivatives as acetylcholinesterase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
EG20726A true EG20726A (en) | 1999-12-29 |
Family
ID=22477461
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EG64694A EG20726A (en) | 1993-10-15 | 1994-10-15 | Process for preparing of galanthamine derivatives as acetylchol inc-sterase inhibitors |
Country Status (23)
Country | Link |
---|---|
US (1) | US6316439B1 (no) |
EP (1) | EP0649846B1 (no) |
JP (1) | JP2664343B2 (no) |
KR (1) | KR100227957B1 (no) |
CN (1) | CN1039910C (no) |
AT (1) | ATE211474T1 (no) |
AU (1) | AU696170B2 (no) |
CA (1) | CA2118172C (no) |
CZ (1) | CZ283731B6 (no) |
DE (1) | DE69429570T2 (no) |
DK (1) | DK0649846T3 (no) |
EG (1) | EG20726A (no) |
ES (1) | ES2170759T3 (no) |
FI (1) | FI108722B (no) |
IL (1) | IL111275A (no) |
NO (1) | NO307464B1 (no) |
NZ (1) | NZ264682A (no) |
PL (1) | PL177549B1 (no) |
PT (1) | PT649846E (no) |
RO (1) | RO114134B1 (no) |
RU (1) | RU2109743C1 (no) |
TW (1) | TW289754B (no) |
ZA (1) | ZA948061B (no) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT403803B (de) | 1996-04-19 | 1998-05-25 | Sanochemia Ltd | Neue benzazepinderivate, diese enthaltende arzneimittel und verwendung derselben zum herstellen von arzneimitteln |
AU780012B2 (en) * | 1999-12-10 | 2005-02-24 | Bonnie Davis | Analogs of galanthamine and lycoramine as modulators of nicotinic receptors |
CN100343258C (zh) * | 2001-04-30 | 2007-10-17 | 美国拜尔公司 | 新的4-氨基-5,6-取代的噻吩并[2,3-d]嘧啶化合物 |
US20030162770A1 (en) * | 2002-02-22 | 2003-08-28 | Davis Bonnie M. | Use of modulators of nicotinic receptors for treatment of cognitive dysfunction |
US20040254146A1 (en) * | 2002-05-21 | 2004-12-16 | Nastech Pharmaceutical Company Inc. | Carboxylate salts of galantamine and their pharmaceutical use |
US20050143350A1 (en) * | 2003-11-19 | 2005-06-30 | Seed John C. | Combination drug therapy to treat obesity |
WO2005065662A1 (en) * | 2003-12-31 | 2005-07-21 | Actavis Group Hf | Solid dosage formulations of galantamine |
WO2005065661A2 (en) * | 2003-12-31 | 2005-07-21 | Actavis Group Hf | Immediate, controlled and sustained release formulations of galanthamine |
EP1779867A4 (en) * | 2004-07-01 | 2009-12-02 | Eisai R&D Man Co Ltd | MEANS FOR PROMOTING NERVE REVENERATION |
EP1827468B1 (en) * | 2004-12-23 | 2012-08-22 | Curaxis Pharmaceutical Corporation | Acetylcholinesterase Inhibitors and leuprolide acetate for the treatment of Alzheimer's disease |
DE602006016441D1 (de) * | 2005-05-13 | 2010-10-07 | Alza Corp | Mehrlagiges arzneimittelausbringsystem mit sperre gegen reservoirmaterialfluss |
US20080188510A1 (en) * | 2005-05-23 | 2008-08-07 | Eisai R & D Management Co., Ltd. | Novel methods using zonisamide |
US20090253654A1 (en) | 2005-09-22 | 2009-10-08 | Galantos Pharma Gmbh | Cholinergic enhancers with improved blood-brain barrier permeability for the treatment of diseases accompanied by cognitive impairment |
US20070104771A1 (en) * | 2005-09-23 | 2007-05-10 | Jay Audett | Transdermal galantamine delivery system |
EP2137192B8 (en) | 2008-04-14 | 2014-06-11 | Neurodyn Life Sciences Inc. | Derivatives of galantamine as pro-drugs for the treatment of human brain diseases |
CN102625700A (zh) * | 2009-07-23 | 2012-08-01 | 夏尔有限责任公司 | 加兰他敏氨基酸和肽前药及其用途 |
EP3142669A2 (en) * | 2014-05-16 | 2017-03-22 | Synaptec Development LLC | CLEARANCE OF AMYLOID ß |
EP4029867A1 (en) | 2021-01-13 | 2022-07-20 | Alpha Cognition Inc. | Solid forms of galantamine benzoate gluconate |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL122665B1 (en) | 1978-11-21 | 1982-08-31 | Edinen Zentar Chim | Process for preparing novel dienones of narvedine type and their derivatives |
US4663318A (en) | 1986-01-15 | 1987-05-05 | Bonnie Davis | Method of treating Alzheimer's disease |
US6150354A (en) * | 1987-01-15 | 2000-11-21 | Bonnie Davis | Compounds for the treatment of Alzheimer's disease |
DE3856594D1 (de) * | 1987-05-04 | 2008-11-27 | Bonnie Davis | Mittel zur behandlung der alzheimer-krankheit |
NL8800350A (nl) | 1988-02-12 | 1989-09-01 | Stichting Biomedical Research | Synthetische galanthamine-derivaten, werkwijze voor het bereiden daarvan, en farmaceutische samenstellingen. |
EP0515301A3 (en) | 1991-05-14 | 1993-06-16 | Ernir Snorrason | Improvements in benzodiazepine treatment by cholinesterterase inhibitors |
US5153193A (en) | 1991-10-01 | 1992-10-06 | Hoechst-Roussel Pharmaceuticals Incorporated | Carbamate derivatives of 4-amino-3-isoxazolidinones, 3-amino-1-hydroxypyrrolidin-2-ones and 1-amino-1-cyclopropanecarboxylic acid analogs |
-
1993
- 1993-10-15 US US08/137,444 patent/US6316439B1/en not_active Expired - Lifetime
-
1994
- 1994-10-10 DK DK94115961T patent/DK0649846T3/da active
- 1994-10-10 ES ES94115961T patent/ES2170759T3/es not_active Expired - Lifetime
- 1994-10-10 EP EP94115961A patent/EP0649846B1/en not_active Expired - Lifetime
- 1994-10-10 DE DE69429570T patent/DE69429570T2/de not_active Expired - Lifetime
- 1994-10-10 AT AT94115961T patent/ATE211474T1/de active
- 1994-10-10 PT PT94115961T patent/PT649846E/pt unknown
- 1994-10-13 NZ NZ264682A patent/NZ264682A/en not_active IP Right Cessation
- 1994-10-13 FI FI944823A patent/FI108722B/fi not_active IP Right Cessation
- 1994-10-13 RU RU94036745A patent/RU2109743C1/ru active
- 1994-10-13 IL IL11127594A patent/IL111275A/xx not_active IP Right Cessation
- 1994-10-14 CZ CZ942545A patent/CZ283731B6/cs not_active IP Right Cessation
- 1994-10-14 PL PL94305457A patent/PL177549B1/pl unknown
- 1994-10-14 ZA ZA948061A patent/ZA948061B/xx unknown
- 1994-10-14 CN CN94117062A patent/CN1039910C/zh not_active Expired - Lifetime
- 1994-10-14 NO NO943895A patent/NO307464B1/no not_active IP Right Cessation
- 1994-10-14 AU AU75813/94A patent/AU696170B2/en not_active Expired
- 1994-10-14 CA CA002118172A patent/CA2118172C/en not_active Expired - Lifetime
- 1994-10-14 RO RO94-01670A patent/RO114134B1/ro unknown
- 1994-10-14 TW TW083109527A patent/TW289754B/zh not_active IP Right Cessation
- 1994-10-14 KR KR1019940026305A patent/KR100227957B1/ko active IP Right Grant
- 1994-10-15 EG EG64694A patent/EG20726A/xx active
- 1994-10-17 JP JP6250777A patent/JP2664343B2/ja not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EG20726A (en) | Process for preparing of galanthamine derivatives as acetylchol inc-sterase inhibitors | |
BG104998A (en) | Isothiazole derivatives useful as anticancer agents | |
RU2088589C1 (en) | Derivatives of 17 beta-substituted-4-aza-5-5 alpha-androstane-3-ones, methods of synthesis of compounds, pharmaceutical composition, compound 4 | |
HUT70536A (en) | Arylsulfonamido-substituted hydroxamic acids, process for preparing them and pharmaceutical compositions containing them | |
NZ225820A (en) | Piperidyl substituted indole derivatives and pharmaceutical compositions | |
ZA896067B (en) | Chemical compounds | |
HUT61555A (en) | Process for producing 2,8-dioxa-bicyclo/3.2.1/octane derivatives and pharmaceutical compositions comprising same | |
EP0807633A3 (en) | Novel 2,3-disubstituted-(5,6)- heteroarylfused-pyrimidine-4-ones | |
TW375615B (en) | Galanthamine derivatives and their use as medicaments | |
ATE104145T1 (de) | 4-substituierten imidazolen zur senkung des intraokularen druckes. | |
CA2252039A1 (en) | Isatin derivatives as acetylcholinesterase inhibitors and analgesics | |
PL309874A1 (en) | Novel derivatives of pyrrolocarbasol, method of obtaining them and pharmaceutical composition containing such derivatives | |
ES2019840A6 (es) | Procedimiento para preparar nuevos derivados de tieno-triazolo-diazepina. | |
IL113780A (en) | Glucopyranoside benzothiophenes process for their preparation and pharmaceutical compositions containing them | |
HUT70761A (en) | Alkyl derivatives of trazodone having action for central nervous system, pharmaceutical compositions for preparing thereof | |
EP1057829A4 (en) | Condensed pyrimidine derivatives and pharmaceutical compositions containing them | |
AU686104B2 (en) | Substituted amidinonaphthyl ester derivatives | |
WO2000008006A3 (en) | Piperidine and piperazine derivatives, process for their preparation and pharmaceutical compounds containing them | |
MXPA99003849A (es) | Derivados 9a, 11b-deshidro de 9-oxima-3-ceto-6-0-metileritromicina. | |
MY103509A (en) | Indole derivatives. |