EE9500075A - 5-atsüül-1,4-dihüdropüridiinide kasutamine - Google Patents

5-atsüül-1,4-dihüdropüridiinide kasutamine

Info

Publication number
EE9500075A
EE9500075A EE9500075A EE9500075A EE9500075A EE 9500075 A EE9500075 A EE 9500075A EE 9500075 A EE9500075 A EE 9500075A EE 9500075 A EE9500075 A EE 9500075A EE 9500075 A EE9500075 A EE 9500075A
Authority
EE
Estonia
Prior art keywords
alkyl
prepn
dichlorophenyl
fluorophenyl
chlorophenyl
Prior art date
Application number
EE9500075A
Other languages
English (en)
Estonian (et)
Inventor
Urbahns Klaus
Heine Hans-Georg
Glaser Thomas
Wittka Reilinde
De Vry Jean-Marie-Viktor
Sommermeyer Henning
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of EE9500075A publication Critical patent/EE9500075A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/96—Sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EE9500075A 1994-12-16 1995-12-15 5-atsüül-1,4-dihüdropüridiinide kasutamine EE9500075A (et)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4444864A DE4444864A1 (de) 1994-12-16 1994-12-16 Verwendung von 5-Acyl-1,4-dihydropyridinen

Publications (1)

Publication Number Publication Date
EE9500075A true EE9500075A (et) 1996-06-17

Family

ID=6535989

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9500075A EE9500075A (et) 1994-12-16 1995-12-15 5-atsüül-1,4-dihüdropüridiinide kasutamine

Country Status (25)

Country Link
US (2) US5646166A (el)
EP (1) EP0717036B1 (el)
JP (1) JPH08239364A (el)
KR (1) KR960022464A (el)
CN (1) CN1130505A (el)
AT (1) ATE177735T1 (el)
AU (1) AU704466B2 (el)
CA (1) CA2165130A1 (el)
CZ (1) CZ332995A3 (el)
DE (2) DE4444864A1 (el)
DK (1) DK0717036T3 (el)
EE (1) EE9500075A (el)
ES (1) ES2130506T3 (el)
FI (1) FI956015A (el)
GR (1) GR3030319T3 (el)
HU (1) HUT74185A (el)
IL (1) IL116387A (el)
NO (1) NO309125B1 (el)
NZ (1) NZ280662A (el)
PL (1) PL311845A1 (el)
RU (1) RU2158259C2 (el)
SI (1) SI0717036T1 (el)
SK (1) SK158195A3 (el)
TW (1) TW381023B (el)
ZA (1) ZA9510693B (el)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1131322A2 (en) * 1998-10-28 2001-09-12 Abbott Laboratories Dihydropyridine compounds and methods of use
WO2002060871A2 (en) * 2001-01-30 2002-08-08 Eli Lilly And Company Benzenesulfonic acid indol-5-yl esters as antagonists of the 5-ht6 receptor
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
US20050075359A1 (en) * 2003-03-14 2005-04-07 Rikako Kono Large conductance calcium-activated K channel opener
WO2006074419A2 (en) * 2005-01-07 2006-07-13 Roskamp Research Llc Compounds for inhibiting beta-amyloid production and methods of identifying the compounds
WO2013076516A1 (en) * 2011-11-24 2013-05-30 Lipidart Kutató Fejlesztő És Tanácsadó Kft. 1,4- dihydropyridine derivatives with hsp modulating activity
CN103420901B (zh) * 2012-05-22 2015-06-17 中国科学院大连化学物理研究所 一种制备1,2-二氢吡啶衍生物的方法
CN103420900B (zh) * 2012-05-22 2015-06-03 中国科学院大连化学物理研究所 一种制备卤代-1,2-二氢吡啶的方法
CN103804283B (zh) * 2012-11-06 2016-04-20 中国科学院大连化学物理研究所 一种制备1,2-二氢吡啶衍生物的方法
CN103804286B (zh) * 2012-11-06 2016-07-06 中国科学院大连化学物理研究所 一种由3-氮杂-1,5-烯炔制备吡啶衍生物的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3966948A (en) 1970-01-24 1976-06-29 Bayer Aktiengesellschaft Spasmolytic, vaso-dilating and anti-hypertensive compositions and methods
DE2018738A1 (en) 1970-04-18 1971-10-28 Farbenfabriken Bayer Ag, 5090 Leverkusen Hydrogenated pyridines, quinolines andacridi
DE2018739A1 (en) 1970-04-18 1971-10-28 Farbenfabriken Bayer Ag, 5090 Leverkusen 1,4-dihydro-3,5-diacyl-4-arylpyridines,coronary active
GB1430961A (en) * 1972-01-22 1976-04-07 Yamanouchi Pharma Co Ltd 1-substituted-1,4-dihyddrypyridine derivatives
FR2649395B1 (fr) * 1989-07-04 1992-11-06 Adir Nouveau derive de la dihydro-1,4 pyridine denomme (-) Ÿi1Ÿ(((amino-2 ethoxy)-2 ethoxy) methylŸi1Ÿ) -2 (dichloro-2,3 phenyl)-4 ethoxycarbonyl-3 methoxycarbonyl-5 methyl-6 dihydro-1,4 pyridine, son procede de preparation et les compositions qui le contiennent
US5446057A (en) * 1993-09-24 1995-08-29 Warner-Lambert Company Substituted tetrahydropyridine and piperidine carboxylic acids as muscarinic antagonists
JP3709997B2 (ja) * 1994-03-29 2005-10-26 日東電工株式会社 耐熱性ネガ型フォトレジスト組成物および感光性基材、ならびにネガ型パターン形成方法

Also Published As

Publication number Publication date
ES2130506T3 (es) 1999-07-01
CZ332995A3 (en) 1996-07-17
GR3030319T3 (en) 1999-09-30
SK158195A3 (en) 1996-09-04
SI0717036T1 (en) 1999-06-30
EP0717036A1 (de) 1996-06-19
NZ280662A (en) 1997-02-24
PL311845A1 (en) 1996-06-24
ATE177735T1 (de) 1999-04-15
NO955104L (no) 1996-06-17
AU4029395A (en) 1996-06-27
US5646166A (en) 1997-07-08
FI956015A (fi) 1996-06-17
RU2158259C2 (ru) 2000-10-27
JPH08239364A (ja) 1996-09-17
CA2165130A1 (en) 1996-06-17
IL116387A (en) 2000-11-21
US5942526A (en) 1999-08-24
DK0717036T3 (da) 1999-10-11
DE59505373D1 (de) 1999-04-22
EP0717036B1 (de) 1999-03-17
DE4444864A1 (de) 1996-06-20
ZA9510693B (en) 1996-07-03
HUT74185A (en) 1996-11-28
KR960022464A (ko) 1996-07-18
NO309125B1 (no) 2000-12-18
TW381023B (en) 2000-02-01
FI956015A0 (fi) 1995-12-14
CN1130505A (zh) 1996-09-11
NO955104D0 (no) 1995-12-15
HU9503592D0 (en) 1996-02-28
IL116387A0 (en) 1996-03-31
AU704466B2 (en) 1999-04-22

Similar Documents

Publication Publication Date Title
IL115572A0 (en) Novel substituted 4-(azanaphthoylamino)-piperidines salts of these and pharmaceutical compositions containing them
EE9500075A (et) 5-atsüül-1,4-dihüdropüridiinide kasutamine
DE3682032D1 (de) Propylamine, verfahren zu ihrer herstellung und ihre verwendung als fungizide.
DK0688771T3 (da) Anvendelse af lactamforbindelser som farmaceutiske aktivstoffer
ZA9710918B (en) Imidazoline compounds, process for preparing them and pharmaceutical compositions containing them.
NO954139L (no) Kinoksaliner, deres fremstilling og anvendelse
EE9500076A (et) 1,2-sillaga 1,4-dihüdropüridiinide kasutamine ravimitena
DE3867563D1 (en) 2-amino-5-hydroxy-4-pyrimidone.
ATE281452T1 (de) 4-amino-2-ureido-pyrimidin-5-carbonsäureamide, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
ATE192155T1 (de) Tetracyclische 1,4-oxazin-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
ATE359993T1 (de) Aminderivate, verfahren zu ihrer herstellung und ihre verwendung als antimykotische mittel
DE59712054D1 (de) 4-Amino-2-ureido-pyrimidin-5-carbonsäureamide, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung