EE9500015A - Meetod pranoprofeeni stabiliseerimiseks ja pranoprofeeni stabiilne vedelpreparaat - Google Patents

Meetod pranoprofeeni stabiliseerimiseks ja pranoprofeeni stabiilne vedelpreparaat

Info

Publication number
EE9500015A
EE9500015A EE9500015A EE9500015A EE9500015A EE 9500015 A EE9500015 A EE 9500015A EE 9500015 A EE9500015 A EE 9500015A EE 9500015 A EE9500015 A EE 9500015A EE 9500015 A EE9500015 A EE 9500015A
Authority
EE
Estonia
Prior art keywords
pranoprofen
aqueous solution
stabilizing
liquid formulation
stable liquid
Prior art date
Application number
EE9500015A
Other languages
English (en)
Inventor
Doi Koji
Sawa Hisako
Ozaki Yoshie
Kimura Yoshiyuki
Original Assignee
Senju Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharmaceutical Co., Ltd. filed Critical Senju Pharmaceutical Co., Ltd.
Publication of EE9500015A publication Critical patent/EE9500015A/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]
    • Y10T428/1352—Polymer or resin containing [i.e., natural or synthetic]
    • Y10T428/139—Open-ended, self-supporting conduit, cylinder, or tube-type article
    • Y10T428/1393—Multilayer [continuous layer]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
EE9500015A 1994-03-15 1995-03-15 Meetod pranoprofeeni stabiliseerimiseks ja pranoprofeeni stabiilne vedelpreparaat EE9500015A (et)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4418494 1994-03-15

Publications (1)

Publication Number Publication Date
EE9500015A true EE9500015A (et) 1995-12-15

Family

ID=12684495

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9500015A EE9500015A (et) 1994-03-15 1995-03-15 Meetod pranoprofeeni stabiliseerimiseks ja pranoprofeeni stabiilne vedelpreparaat

Country Status (19)

Country Link
US (2) US5856345A (et)
EP (2) EP1163906A3 (et)
KR (1) KR100338851B1 (et)
CN (1) CN1091597C (et)
AT (1) ATE297206T1 (et)
AU (1) AU707119B2 (et)
BR (1) BR9501081A (et)
CA (1) CA2144591A1 (et)
DE (1) DE69534258T2 (et)
EE (1) EE9500015A (et)
ES (1) ES2240966T3 (et)
FI (1) FI951190A (et)
HU (1) HUT71245A (et)
LT (1) LT3969B (et)
LV (1) LV10922B (et)
NO (1) NO950970L (et)
PL (1) PL179534B1 (et)
RU (1) RU2148402C1 (et)
TW (1) TW358812B (et)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6235781B1 (en) 1998-07-14 2001-05-22 Alcon Laboratories, Inc. Prostaglandin product
WO2000032157A1 (en) * 1998-12-02 2000-06-08 Copa Distributors, Llc Gradual hair relaxation composition
US8877168B1 (en) 2002-07-31 2014-11-04 Senju Pharmaceuticals Co., Ltd. Aqueous liquid preparations and light-stabilized aqueous liquid preparations
WO2004010974A2 (en) * 2002-07-31 2004-02-05 Pharmacia Corporation Gelatin capsule exhibiting reduced cross-linking
EP1525884B1 (en) * 2002-07-31 2011-10-12 Senju Pharmaceutical Co., Ltd. Aqueous liquid preparations and light-stabilized aqueous liquid preparations
ES2301964T3 (es) 2003-01-21 2008-07-01 Senju Pharmaceutical Co., Ltd. Preparado liquido acuoso que contiene acido 2-amino-3-(4-bromobenzoil)fenilacetico.
CA2521603A1 (en) * 2003-04-07 2004-10-21 Jurox Pty Ltd Stable carprofen composition
US7125497B1 (en) * 2003-05-22 2006-10-24 Sandia Corporation Reactive formulations for a neutralization of toxic industrial chemicals
WO2004112837A1 (ja) * 2003-05-23 2004-12-29 Hisamitsu Pharmaceutical Co., Inc. 非ステロイド系消炎鎮痛剤含有外用経皮製剤およびインターロイキン－１α生成抑制剤
US20060073172A1 (en) * 2004-10-01 2006-04-06 Schneider L W Stabilized ophthalmic solution for the treatment of glaucoma and lowering intraocular pressure
ES2363964B1 (es) 2009-11-20 2012-08-22 Gp Pharm, S.A. Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados.
CN104010661B (zh) * 2011-12-27 2017-06-06 千寿制药株式会社 含有二丁基羟基甲苯的制剂及二丁基羟基甲苯的稳定化方法
IN2014MN01555A (et) * 2012-02-27 2015-07-03 Rohto Pharma
WO2014129466A1 (ja) * 2013-02-19 2014-08-28 ロート製薬株式会社 網膜疾患の予防、改善、又は治療用粘膜適用剤
JP5340498B1 (ja) * 2013-03-11 2013-11-13 千寿製薬株式会社 ソフトコンタクトレンズ用眼科用組成物
RU2674657C2 (ru) * 2013-05-30 2018-12-12 Сэндзю Фармасьютикал Ко., Лтд. Способ стабилизации хлорфенирамина и его соли
TWI644663B (zh) * 2014-03-10 2018-12-21 日商千壽製藥股份有限公司 二丁基羥基甲苯的穩定化方法，及含二丁基羥基甲苯之製品(一)
TW201540292A (zh) * 2014-03-10 2015-11-01 Senju Pharma Co 二丁基羥基甲苯的穩定化方法（二）
AR102172A1 (es) 2015-10-05 2017-02-08 Química Luar S R L Una composición farmacéutica bactericida y virucida
KR102478553B1 (ko) * 2018-02-28 2022-12-16 한림제약(주) 벤조피란 유도체 또는 이의 약학적으로 허용가능한 염을 포함하는 용액 형태의 점안제
CN115677733A (zh) * 2022-12-20 2023-02-03 济南宣正药业有限公司 一种用于普拉洛芬质量研究的化合物及其制备方法和应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3931295A (en) 1974-07-23 1976-01-06 Universal Oil Products Company Hydroxylation of aromatic compounds
JPS6056684B2 (ja) * 1977-11-07 1985-12-11 東興薬品工業株式会社 点眼剤
US4565851A (en) * 1983-04-25 1986-01-21 Eastman Kodak Company Containers having improved gas barrier properties
US4525348A (en) * 1983-12-19 1985-06-25 Yoshitomi Pharmaceutical Industries, Ltd. Pranoprofen gelled ointment
JPS60184013A (ja) 1984-03-01 1985-09-19 Yoshitomi Pharmaceut Ind Ltd 点眼剤
JPS61130222A (ja) * 1984-11-30 1986-06-18 Kureha Chem Ind Co Ltd 抗腫瘍剤
US4940728A (en) * 1985-05-17 1990-07-10 Postley John E Treatment for sino-nasal congestion
US5110492A (en) * 1985-05-24 1992-05-05 Irene Casey Cleaner and disinfectant with dye
US5032392A (en) * 1986-09-04 1991-07-16 Vision Pharmaceuticals Aqueous ophthalmic solutions for the treatment of dryness and/or irritation of human or animal eyes
US5414011A (en) * 1987-09-11 1995-05-09 Syntex (U.S.A.) Inc. Preservative system for ophthalmic formulations
US5110493A (en) * 1987-09-11 1992-05-05 Syntex (U.S.A.) Inc. Ophthalmic NSAID formulations containing a quaternary ammonium preservative and a nonionic surfactant
AU634358B2 (en) * 1990-03-02 1993-02-18 Shiseido Company Ltd. Oil-in-water emulsion composition containing nonsteroidal antiphlogistic analgesic
TW206918B (et) * 1991-05-11 1993-06-01 Kuko Seiyaku Kk
JPH05124092A (ja) * 1991-11-06 1993-05-21 Chisso Corp ポリオレフイン系樹脂製中空容器
CA2153553A1 (en) * 1994-07-13 1996-01-14 Hidekazu Suzuki Stable lipid emulsion

Also Published As

Publication number Publication date
KR100338851B1 (ko) 2002-10-12
DE69534258D1 (de) 2005-07-14
LT3969B (en) 1996-05-27
LT95028A (en) 1995-10-25
US5889030A (en) 1999-03-30
LV10922A (lv) 1995-12-20
KR950032201A (ko) 1995-12-20
TW358812B (en) 1999-05-21
CA2144591A1 (en) 1995-09-16
DE69534258T2 (de) 2006-05-04
EP0672414B1 (en) 2005-06-08
RU2148402C1 (ru) 2000-05-10
FI951190A (fi) 1995-09-16
AU1485295A (en) 1995-09-21
HU9500772D0 (en) 1995-04-28
AU707119B2 (en) 1999-07-01
ES2240966T3 (es) 2005-10-16
ATE297206T1 (de) 2005-06-15
FI951190A0 (fi) 1995-03-14
NO950970L (no) 1995-09-18
PL179534B1 (pl) 2000-09-29
CN1111510A (zh) 1995-11-15
LV10922B (en) 1996-08-20
NO950970D0 (no) 1995-03-14
US5856345A (en) 1999-01-05
PL307671A1 (en) 1995-09-18
EP1163906A3 (en) 2003-05-21
CN1091597C (zh) 2002-10-02
EP0672414A2 (en) 1995-09-20
BR9501081A (pt) 1996-06-04
EP0672414A3 (en) 1995-12-13
HUT71245A (en) 1995-11-28
EP1163906A2 (en) 2001-12-19

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