EE200100698A - Kristallilise (2-benshüdrüül-1-asabitsüklo[2,2,2]okt-3-üül)-(5-isopropüül-2-metoksübensüül)-ammooniumk loriidi polümorfid kui NK-1 retseptori antagonistid - Google Patents
Kristallilise (2-benshüdrüül-1-asabitsüklo[2,2,2]okt-3-üül)-(5-isopropüül-2-metoksübensüül)-ammooniumk loriidi polümorfid kui NK-1 retseptori antagonistidInfo
- Publication number
- EE200100698A EE200100698A EEP200100698A EEP200100698A EE200100698A EE 200100698 A EE200100698 A EE 200100698A EE P200100698 A EEP200100698 A EE P200100698A EE P200100698 A EEP200100698 A EE P200100698A EE 200100698 A EE200100698 A EE 200100698A
- Authority
- EE
- Estonia
- Prior art keywords
- benzhydryl
- azabicyclo
- polymorphs
- methoxybenzyl
- oct
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14023399P | 1999-06-22 | 1999-06-22 | |
| PCT/IB2000/000756 WO2000078759A1 (en) | 1999-06-22 | 2000-06-06 | Polymorphs of crystalline (2-benzhydryl-1-azabicyclo[2,2,2]oct-3-yl)-(5-isopropyl-2-methoxybenzyl)-ammoniumchloride as nk-1 receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EE200100698A true EE200100698A (et) | 2003-02-17 |
Family
ID=22490317
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200100698A EE200100698A (et) | 1999-06-22 | 2000-06-06 | Kristallilise (2-benshüdrüül-1-asabitsüklo[2,2,2]okt-3-üül)-(5-isopropüül-2-metoksübensüül)-ammooniumk loriidi polümorfid kui NK-1 retseptori antagonistid |
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US6262067B1 (ru) |
| EP (1) | EP1187834A1 (ru) |
| JP (1) | JP2003502425A (ru) |
| KR (1) | KR20020030280A (ru) |
| CN (1) | CN1390216A (ru) |
| AP (1) | AP2001002367A0 (ru) |
| AR (1) | AR024411A1 (ru) |
| AU (1) | AU767336B2 (ru) |
| BG (1) | BG106205A (ru) |
| BR (1) | BR0011835A (ru) |
| CA (1) | CA2375265A1 (ru) |
| CO (1) | CO5190663A1 (ru) |
| CZ (1) | CZ20014458A3 (ru) |
| DZ (1) | DZ3055A1 (ru) |
| EA (1) | EA004264B1 (ru) |
| EC (1) | ECSP003538A (ru) |
| EE (1) | EE200100698A (ru) |
| HR (1) | HRP20010920A2 (ru) |
| HU (1) | HUP0201694A3 (ru) |
| IL (1) | IL146410A0 (ru) |
| IS (1) | IS6161A (ru) |
| MA (1) | MA26744A1 (ru) |
| MX (1) | MXPA02000033A (ru) |
| NO (1) | NO20016187L (ru) |
| NZ (1) | NZ515348A (ru) |
| OA (1) | OA11952A (ru) |
| PA (1) | PA8496701A1 (ru) |
| PE (1) | PE20010322A1 (ru) |
| PL (1) | PL352899A1 (ru) |
| SK (1) | SK18672001A3 (ru) |
| TN (1) | TNSN00137A1 (ru) |
| TR (1) | TR200103688T2 (ru) |
| UY (1) | UY26211A1 (ru) |
| WO (1) | WO2000078759A1 (ru) |
| ZA (1) | ZA200110387B (ru) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6387925B1 (en) * | 1999-06-01 | 2002-05-14 | Pfizer Inc. | Polymorphs of a crystalline azo-bicyclo (2.2.2) oct-3-yl amine citrate and their pharmaceutical compositions |
| US6939873B2 (en) * | 2000-07-26 | 2005-09-06 | Taro Pharmaceuticals Industries Limited | Non-sedating barbituric acid derivatives |
| US6756379B2 (en) * | 2001-07-26 | 2004-06-29 | Taro Pharmaceutical Industries Ltd. | Non-sedating barbiturate compounds as neuroprotective agents |
| US7166610B2 (en) | 2002-12-11 | 2007-01-23 | Taro Pharmaceuticals U.S.A., Inc. | Method of treating movement disorders using barbituric acid derivatives |
| US7683071B2 (en) * | 2000-07-26 | 2010-03-23 | Taro Pharmaceuticals Industries Ltd. | Composition and method for improved bioavailability and enhanced brain delivery of 5,5-diphenyl barbituric acid |
| JP2006503859A (ja) * | 2002-10-04 | 2006-02-02 | メルク シャープ エンド ドーム リミテッド | 受容体拮抗薬としてのアザ二環式スピロエーテル誘導体 |
| CA2572797A1 (en) * | 2004-07-02 | 2006-01-12 | Daniella Gutman | A process for preparing 1-methoxymethyl-5,5-diphenylbarbituric acid |
| US20080132529A1 (en) * | 2006-11-14 | 2008-06-05 | Avraham Yacobi | Method of improving bioavailability for non-sedating barbiturates |
| UA102128C2 (en) * | 2008-12-05 | 2013-06-10 | Х. Луннбек А/С | Nalmefene hydrochloride dihydrate |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX18467A (es) * | 1988-11-23 | 1993-07-01 | Pfizer | Agentes terapeuticos de quinuclidinas |
| US5807867A (en) * | 1991-05-31 | 1998-09-15 | Pfizer Inc. | Quinuclidine derivatives |
| DE69307340T2 (de) * | 1992-11-12 | 1997-04-24 | Pfizer | Chinuclidin derivat als substanz p antagonist |
| US5393762A (en) * | 1993-06-04 | 1995-02-28 | Pfizer Inc. | Pharmaceutical agents for treatment of emesis |
-
2000
- 2000-05-04 US US09/564,528 patent/US6262067B1/en not_active Expired - Fee Related
- 2000-06-06 EP EP00929745A patent/EP1187834A1/en not_active Withdrawn
- 2000-06-06 HU HU0201694A patent/HUP0201694A3/hu unknown
- 2000-06-06 TR TR2001/03688T patent/TR200103688T2/xx unknown
- 2000-06-06 CN CN00809305A patent/CN1390216A/zh active Pending
- 2000-06-06 PL PL00352899A patent/PL352899A1/xx not_active Application Discontinuation
- 2000-06-06 AP APAP/P/2001/002367A patent/AP2001002367A0/en unknown
- 2000-06-06 CZ CZ20014458A patent/CZ20014458A3/cs unknown
- 2000-06-06 IL IL14641000A patent/IL146410A0/xx unknown
- 2000-06-06 SK SK1867-2001A patent/SK18672001A3/sk unknown
- 2000-06-06 JP JP2001504925A patent/JP2003502425A/ja active Pending
- 2000-06-06 WO PCT/IB2000/000756 patent/WO2000078759A1/en not_active Application Discontinuation
- 2000-06-06 EE EEP200100698A patent/EE200100698A/xx unknown
- 2000-06-06 BR BR0011835-4A patent/BR0011835A/pt not_active IP Right Cessation
- 2000-06-06 KR KR1020017016407A patent/KR20020030280A/ko not_active Application Discontinuation
- 2000-06-06 NZ NZ515348A patent/NZ515348A/en unknown
- 2000-06-06 PA PA20008496701A patent/PA8496701A1/es unknown
- 2000-06-06 EA EA200101179A patent/EA004264B1/ru not_active IP Right Cessation
- 2000-06-06 OA OA1200100314A patent/OA11952A/en unknown
- 2000-06-06 AU AU47745/00A patent/AU767336B2/en not_active Ceased
- 2000-06-06 CA CA002375265A patent/CA2375265A1/en not_active Abandoned
- 2000-06-06 MX MXPA02000033A patent/MXPA02000033A/es unknown
- 2000-06-13 CO CO00043885A patent/CO5190663A1/es not_active Application Discontinuation
- 2000-06-20 UY UY26211A patent/UY26211A1/es not_active Application Discontinuation
- 2000-06-20 PE PE2000000613A patent/PE20010322A1/es not_active Application Discontinuation
- 2000-06-20 AR ARP000103053A patent/AR024411A1/es not_active Application Discontinuation
- 2000-06-21 MA MA26007A patent/MA26744A1/fr unknown
- 2000-06-21 DZ DZ000113A patent/DZ3055A1/xx active
- 2000-06-21 TN TNTNSN00137A patent/TNSN00137A1/fr unknown
- 2000-06-22 EC EC2000003538A patent/ECSP003538A/es unknown
-
2001
- 2001-11-13 IS IS6161A patent/IS6161A/is unknown
- 2001-12-10 BG BG106205A patent/BG106205A/bg unknown
- 2001-12-11 HR HR20010920A patent/HRP20010920A2/hr not_active Application Discontinuation
- 2001-12-18 NO NO20016187A patent/NO20016187L/no not_active Application Discontinuation
- 2001-12-19 ZA ZA200110387A patent/ZA200110387B/en unknown
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