EE03525B1 - Kompositsioonid nuumrakkude vahendatud põletikuliste seisundite raviks - Google Patents
Kompositsioonid nuumrakkude vahendatud põletikuliste seisundite raviksInfo
- Publication number
- EE03525B1 EE03525B1 EE9700089A EE9700089A EE03525B1 EE 03525 B1 EE03525 B1 EE 03525B1 EE 9700089 A EE9700089 A EE 9700089A EE 9700089 A EE9700089 A EE 9700089A EE 03525 B1 EE03525 B1 EE 03525B1
- Authority
- EE
- Estonia
- Prior art keywords
- compositions
- treatment
- mast cell
- inflammatory conditions
- mediated inflammatory
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/32—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C271/34—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31226994A | 1994-09-23 | 1994-09-23 | |
| PCT/US1995/011814 WO1996009297A1 (en) | 1994-09-23 | 1995-09-14 | Compositions and methods for treating mast-cell inflammatory condition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EE9700089A EE9700089A (et) | 1997-10-15 |
| EE03525B1 true EE03525B1 (et) | 2001-10-15 |
Family
ID=23210670
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EE9700089A EE03525B1 (et) | 1994-09-23 | 1995-09-14 | Kompositsioonid nuumrakkude vahendatud põletikuliste seisundite raviks |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US6022969A (cs) |
| EP (1) | EP0782571A1 (cs) |
| JP (1) | JPH10506390A (cs) |
| KR (1) | KR970706267A (cs) |
| CN (1) | CN1160398A (cs) |
| AU (1) | AU694275B2 (cs) |
| CA (1) | CA2200561A1 (cs) |
| CZ (1) | CZ87097A3 (cs) |
| EE (1) | EE03525B1 (cs) |
| FI (1) | FI971171A (cs) |
| HR (1) | HRP950499B1 (cs) |
| HU (1) | HUT77770A (cs) |
| IL (1) | IL115405A (cs) |
| LT (1) | LT4234B (cs) |
| LV (1) | LV11865B (cs) |
| MX (1) | MX9702125A (cs) |
| NO (1) | NO309605B1 (cs) |
| NZ (1) | NZ294392A (cs) |
| PL (1) | PL183552B1 (cs) |
| RU (1) | RU2159229C2 (cs) |
| SI (1) | SI9520101A (cs) |
| SK (1) | SK37997A3 (cs) |
| TW (1) | TW442478B (cs) |
| WO (1) | WO1996009297A1 (cs) |
| ZA (1) | ZA958028B (cs) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ29799A3 (cs) * | 1996-07-30 | 1999-06-16 | Arris Pharmaceutical Corporation | Disubstituovaná cyklická sloučenina, způsob její výroby, farmaceutický přípravek a způsob léčení onemocnění živočicha |
| WO1998024886A1 (en) * | 1996-12-04 | 1998-06-11 | Brigham And Women's Hospital, Inc. | Mast cell protease that cleaves fibrinogen |
| WO1998033812A1 (en) * | 1997-02-05 | 1998-08-06 | Brigham And Women's Hospital, Inc. | Mast cell protease peptide inhibitors |
| AU8997498A (en) * | 1997-09-05 | 1999-03-29 | Yoshitomi Pharmaceutical Industries, Ltd. | Tryptase inhibitor |
| AU1208999A (en) * | 1997-11-10 | 1999-05-31 | Array Biopharma, Inc. | Compounds which inhibit tryptase activity |
| US6221914B1 (en) * | 1997-11-10 | 2001-04-24 | Array Biopharma Inc. | Sulfonamide bridging compounds that inhibit tryptase activity |
| ES2233025T3 (es) | 1998-02-06 | 2005-06-01 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Agente inhibidores de la triptasa. |
| US6613769B1 (en) | 1998-02-06 | 2003-09-02 | Max-Planck-Gesellschaft zur Föderung der Wissenschaften. e.V. | Tryptase inhibitors |
| JP2003524598A (ja) * | 1998-09-04 | 2003-08-19 | アルタナ ファルマ アクチエンゲゼルシャフト | 新規ピラノセン |
| US6362216B1 (en) | 1998-10-27 | 2002-03-26 | Array Biopharma Inc. | Compounds which inhibit tryptase activity |
| US6849605B1 (en) * | 1999-03-05 | 2005-02-01 | The Trustees Of University Technology Corporation | Inhibitors of serine protease activity, methods and compositions for treatment of viral infections |
| AU3731400A (en) * | 1999-03-05 | 2000-09-21 | Trustees Of University Technology Corporation, The | Methods and compositions useful in inhibiting apoptosis |
| IL147649A0 (en) * | 1999-08-10 | 2002-08-14 | Byk Gulden Lomberg Chem Fab | Tryptase inhibitors |
| WO2001019809A1 (en) * | 1999-09-14 | 2001-03-22 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Tryptase inhibitors |
| GB9923710D0 (en) * | 1999-10-08 | 1999-12-08 | Proteus Molecular Design | Chemical compounds |
| AU1413301A (en) * | 1999-11-17 | 2001-05-30 | Sumitomo Pharmaceuticals Company, Limited | Diabetic remedy containing dipiperazine derivative |
| AU783217B2 (en) * | 1999-12-20 | 2005-10-06 | Altana Pharma Ag | Tryptase inhibitors |
| EP1244614B1 (en) * | 1999-12-20 | 2004-06-02 | ALTANA Pharma AG | Tryptase inhibitors |
| AU2001231030A1 (en) * | 2000-01-20 | 2001-07-31 | Amgen Inc | Inhibitors of protease-activated receptor-2 (par-2) as novel asthma therapeutics |
| US20020045613A1 (en) * | 2000-04-27 | 2002-04-18 | Heinz Pauls | 1-aroyl-piperidinyl benzamidines |
| AU2002238522B8 (en) * | 2001-01-31 | 2007-01-18 | Altana Pharma Ag | Diazocine derivatives and their use as tryptase inhibitors |
| CA2438685A1 (en) | 2001-02-21 | 2002-08-29 | Altana Pharma Ag | Tryptase inhibitors |
| CA2438711A1 (en) | 2001-02-21 | 2002-08-29 | Altana Pharma Ag | Tryptase inhibitors |
| JP2004525926A (ja) * | 2001-03-15 | 2004-08-26 | アルタナ ファルマ アクチエンゲゼルシャフト | トリプターゼ阻害剤 |
| WO2002074732A2 (en) * | 2001-03-15 | 2002-09-26 | Altana Pharma Ag | Tryptase-inhibitors |
| US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US7186855B2 (en) * | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US7232924B2 (en) * | 2001-06-11 | 2007-06-19 | Xenoport, Inc. | Methods for synthesis of acyloxyalkyl derivatives of GABA analogs |
| US6818787B2 (en) | 2001-06-11 | 2004-11-16 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| EP1401809B1 (en) | 2001-06-19 | 2006-12-20 | ALTANA Pharma AG | Tryptase inhibitors |
| EP1455765A2 (en) * | 2001-12-13 | 2004-09-15 | Kowa Company Ltd. | Use of protease-activated receptor-2 inhibitor in the manufacture of a medicament for treating delayed hypersensitivity |
| WO2003075853A2 (en) | 2002-03-08 | 2003-09-18 | Bristol-Myers Squibb Company | Cyclic derivatives as modulators of chemokine receptor activity |
| TW200524849A (en) * | 2003-07-02 | 2005-08-01 | Hoffmann La Roche | Hydroxyalkylamide derivatives |
| US20050255154A1 (en) * | 2004-05-11 | 2005-11-17 | Lena Pereswetoff-Morath | Method and composition for treating rhinitis |
| TW200815351A (en) * | 2006-05-02 | 2008-04-01 | Astrazeneca Ab | Novel compounds |
| TWI414527B (zh) * | 2010-10-06 | 2013-11-11 | Ind Tech Res Inst | 異山梨糖醇衍生物及包含該衍生物之液晶顯示器 |
| CN102453037B (zh) * | 2010-10-25 | 2014-06-25 | 财团法人工业技术研究院 | 异山梨糖醇衍生物及包含该衍生物的液晶显示器 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR208414A1 (es) * | 1974-11-07 | 1976-12-27 | Rhone Poulenc Ind | Procedimiento para obtener nuevos derivados de la((acil-4piperazinil-1)carboniloxi-5 pirrolinona-2) |
| US4746737A (en) * | 1985-07-26 | 1988-05-24 | Kowa Co., Ltd. | Phenyl guanidinobenzoate derivatives which have protease inhibitory activity |
| NZ263084A (en) * | 1993-03-12 | 1997-08-22 | Arris Pharm Corp | Dipeptide derivatives, treatment of immunomediated inflammatory disorders |
| CZ289930B6 (cs) * | 1993-03-12 | 2002-04-17 | Axys Pharmaceuticals, Inc. | Arylové a heteroarylové peptidové deriváty a farmaceutické prostředky je obsahující |
| ATE189211T1 (de) * | 1994-06-01 | 2000-02-15 | Axys Pharm Inc | Zusammensetzungen und verfahren zur behandlung von durch mast-zellen verursachten krankheiten |
-
1995
- 1995-09-14 WO PCT/US1995/011814 patent/WO1996009297A1/en not_active Application Discontinuation
- 1995-09-14 SK SK379-97A patent/SK37997A3/sk unknown
- 1995-09-14 CA CA002200561A patent/CA2200561A1/en not_active Abandoned
- 1995-09-14 SI SI9520101A patent/SI9520101A/sl unknown
- 1995-09-14 MX MX9702125A patent/MX9702125A/es not_active IP Right Cessation
- 1995-09-14 PL PL95319587A patent/PL183552B1/pl unknown
- 1995-09-14 CZ CZ97870A patent/CZ87097A3/cs unknown
- 1995-09-14 NZ NZ294392A patent/NZ294392A/xx unknown
- 1995-09-14 KR KR1019970701960A patent/KR970706267A/ko not_active Application Discontinuation
- 1995-09-14 US US08/522,157 patent/US6022969A/en not_active Expired - Fee Related
- 1995-09-14 HU HU9702059A patent/HUT77770A/hu unknown
- 1995-09-14 RU RU97106347/04A patent/RU2159229C2/ru not_active IP Right Cessation
- 1995-09-14 CN CN95195191A patent/CN1160398A/zh active Pending
- 1995-09-14 EP EP95934993A patent/EP0782571A1/en not_active Withdrawn
- 1995-09-14 JP JP8511002A patent/JPH10506390A/ja not_active Ceased
- 1995-09-14 AU AU37180/95A patent/AU694275B2/en not_active Ceased
- 1995-09-14 EE EE9700089A patent/EE03525B1/xx not_active IP Right Cessation
- 1995-09-22 IL IL11540595A patent/IL115405A/en not_active IP Right Cessation
- 1995-09-22 ZA ZA958028A patent/ZA958028B/xx unknown
- 1995-09-22 HR HR950499A patent/HRP950499B1/xx not_active IP Right Cessation
- 1995-09-26 TW TW084110031A patent/TW442478B/zh active
-
1997
- 1997-03-20 FI FI971171A patent/FI971171A/fi unknown
- 1997-03-20 NO NO971305A patent/NO309605B1/no unknown
- 1997-04-10 LT LT97-065A patent/LT4234B/lt not_active IP Right Cessation
- 1997-04-22 LV LVP-97-70A patent/LV11865B/en unknown
-
1999
- 1999-03-29 US US09/280,227 patent/US6211228B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0782571A1 (en) | 1997-07-09 |
| TW442478B (en) | 2001-06-23 |
| AU3718095A (en) | 1996-04-09 |
| IL115405A (en) | 2002-07-25 |
| CZ87097A3 (en) | 1997-11-12 |
| NO971305D0 (no) | 1997-03-20 |
| WO1996009297A1 (en) | 1996-03-28 |
| MX9702125A (es) | 1998-04-30 |
| LT4234B (en) | 1997-10-27 |
| KR970706267A (ko) | 1997-11-03 |
| CA2200561A1 (en) | 1996-03-28 |
| CN1160398A (zh) | 1997-09-24 |
| HRP950499A2 (en) | 1997-08-31 |
| NO309605B1 (no) | 2001-02-26 |
| JPH10506390A (ja) | 1998-06-23 |
| LT97065A (en) | 1997-08-25 |
| FI971171A0 (fi) | 1997-03-20 |
| SK37997A3 (en) | 1998-12-02 |
| PL319587A1 (en) | 1997-08-18 |
| SI9520101A (en) | 1997-12-31 |
| US6211228B1 (en) | 2001-04-03 |
| PL183552B1 (pl) | 2002-06-28 |
| NZ294392A (en) | 1999-05-28 |
| HUT77770A (hu) | 1998-08-28 |
| RU2159229C2 (ru) | 2000-11-20 |
| FI971171A (fi) | 1997-03-20 |
| LV11865B (en) | 1998-01-20 |
| ZA958028B (en) | 1996-04-18 |
| NO971305L (no) | 1997-05-06 |
| US6022969A (en) | 2000-02-08 |
| HRP950499B1 (en) | 2003-04-30 |
| LV11865A (lv) | 1997-10-20 |
| EE9700089A (et) | 1997-10-15 |
| IL115405A0 (en) | 1995-12-31 |
| AU694275B2 (en) | 1998-07-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB4A | Valid patent at the end of a year |
Effective date: 20021231 |
|
| KB4A | Valid patent at the end of a year |
Effective date: 20031231 |
|
| MM4A | Lapsed by not paying the annual fees |
Effective date: 20030914 |