EE03265B1 - Valu vaigistavad opioidpeptiidid ja nende kasutamine - Google Patents
Valu vaigistavad opioidpeptiidid ja nende kasutamineInfo
- Publication number
- EE03265B1 EE03265B1 EE9600071A EE9600071A EE03265B1 EE 03265 B1 EE03265 B1 EE 03265B1 EE 9600071 A EE9600071 A EE 9600071A EE 9600071 A EE9600071 A EE 9600071A EE 03265 B1 EE03265 B1 EE 03265B1
- Authority
- EE
- Estonia
- Prior art keywords
- peptides
- pain
- opioid
- relieved
- compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9403263A GB9403263D0 (en) | 1994-02-21 | 1994-02-21 | Novel opiod peptides |
GB9408179A GB9408179D0 (en) | 1994-02-21 | 1994-04-25 | Novel opioid peptides for the treatment of pain and use thereof |
SE9401519A SE9401519D0 (sv) | 1994-05-03 | 1994-05-03 | Novel opioid peptides for the tratment of pain and use thereof |
PCT/SE1995/000158 WO1995022557A1 (en) | 1994-02-21 | 1995-02-15 | Novel opioid peptides for the treatment of pain and use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
EE03265B1 true EE03265B1 (et) | 2000-04-17 |
Family
ID=27267061
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EE9600071A EE03265B1 (et) | 1994-02-21 | 1995-02-15 | Valu vaigistavad opioidpeptiidid ja nende kasutamine |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP0746567B1 (et) |
JP (1) | JPH09509168A (et) |
AT (1) | ATE217011T1 (et) |
BR (1) | BR9506847A (et) |
CA (1) | CA2181367A1 (et) |
CZ (1) | CZ288523B6 (et) |
DE (1) | DE69526577T2 (et) |
EE (1) | EE03265B1 (et) |
ES (1) | ES2176322T3 (et) |
FI (1) | FI963252A0 (et) |
HR (1) | HRP950413A2 (et) |
HU (1) | HUT74731A (et) |
IS (1) | IS4261A (et) |
MX (1) | MX9603489A (et) |
NO (1) | NO963464L (et) |
NZ (1) | NZ281742A (et) |
PL (1) | PL181092B1 (et) |
SK (1) | SK93596A3 (et) |
TW (1) | TW408131B (et) |
WO (1) | WO1995022557A1 (et) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9503924D0 (sv) * | 1995-08-18 | 1995-11-07 | Astra Ab | Novel opioid peptides |
ATE223927T1 (de) * | 1995-06-07 | 2002-09-15 | Torrey Pines Inst | Mu-opioidligande: agonisten und antagonisten |
GB9516994D0 (en) * | 1995-08-18 | 1995-10-18 | Iaf Biochem Int | Solution synthesis of peripheral acting analgestic opioid tetrapeptides |
MX9709494A (es) * | 1996-12-04 | 1998-07-31 | Pfizer | Compuestos peptidicos ciclicos, procedimiento para su produccion, composiciones que los contienen y uso de los mismos. |
US5885958A (en) * | 1997-03-25 | 1999-03-23 | Administrators Of The Tulane Educational Fund | Mu-opiate receptor peptides |
US6548637B1 (en) | 1998-06-18 | 2003-04-15 | Sepracor, Inc. | Ligands for opioid receptors |
SE9900961D0 (sv) * | 1999-03-16 | 1999-03-16 | Astra Ab | Novel compounds |
US7115664B2 (en) | 2000-03-16 | 2006-10-03 | Sepracor Inc. | Peptidomimetic ligands for cellular receptors and ion channels |
DE60143945D1 (de) | 2000-07-18 | 2011-03-10 | Cornell Res Foundation Inc | Medizinische verwendung von agonisten des mu-opioid rezeptors |
HUE027110T2 (en) | 2003-02-04 | 2016-08-29 | Cornell Res Foundation Inc | Use of an aromatic cationic peptide |
CN100506841C (zh) | 2003-05-01 | 2009-07-01 | 科内尔研究基金会 | 将分子递送到细胞的方法和载体复合物 |
RU2376028C2 (ru) | 2004-01-23 | 2009-12-20 | Корнелл Рисеч Фаундейшн, Инк. | Способ уменьшения окислительного повреждения (варианты) |
EA200701852A1 (ru) | 2005-04-28 | 2008-04-28 | Пфайзер Лимитед | Производные аминокислот |
EP1931369B1 (en) | 2005-09-16 | 2016-08-17 | Cornell Research Foundation, Inc. | Aromatic-cationic peptide for use in a method for reducing CD36 expression |
EP1782819A1 (en) | 2005-11-03 | 2007-05-09 | Cognis IP Management GmbH | Oligopeptides and their use |
US7842662B2 (en) | 2006-11-10 | 2010-11-30 | Cara Therapeutics, Inc. | Synthetic peptide amide dimers |
US8906859B2 (en) | 2006-11-10 | 2014-12-09 | Cera Therapeutics, Inc. | Uses of kappa opioid synthetic peptide amides |
NZ577107A (en) | 2006-11-10 | 2012-01-12 | Cara Therapeutics Inc | Synthetic peptide amide ligands of the kappa opiod receptor |
US8236766B2 (en) | 2006-11-10 | 2012-08-07 | Cara Therapeutics, Inc. | Uses of synthetic peptide amides |
US7713937B2 (en) | 2006-11-10 | 2010-05-11 | Cara Therapeutics, Inc. | Synthetic peptide amides and dimeric forms thereof |
CN102127151B (zh) * | 2007-06-11 | 2012-07-04 | 北京大学 | 抗阿片肽的拮抗肽与该拮抗肽的应用 |
CN102127152B (zh) * | 2007-06-11 | 2012-07-04 | 北京大学 | 一种抗阿片肽的拮抗肽与该拮抗肽的应用 |
CN101805396B (zh) * | 2007-06-28 | 2011-09-14 | 北京大学 | 抗阿片肽的拮抗肽与该拮抗肽的应用 |
CN101817877B (zh) * | 2007-06-28 | 2011-09-14 | 北京大学 | 一种抗阿片肽的活性片段 |
EP2712620A1 (en) | 2008-02-07 | 2014-04-02 | Cornell University | Methods for Preventing or Treating Insulin Resistance |
EP2262520B1 (en) | 2008-02-26 | 2017-05-03 | Cornell University | Compositions for prevention and treatment of renal injury |
CN112469729A (zh) * | 2018-05-31 | 2021-03-09 | 悉尼大学 | 镇痛剂及其使用方法 |
JP7437578B2 (ja) * | 2019-03-20 | 2024-02-26 | 国立大学法人東北大学 | 新規オピオイドペプチド、その糖鎖付加体及びそれらを含む医薬組成物 |
CN113968902B (zh) * | 2020-07-25 | 2023-05-26 | 兰州大学 | 亮氨酸-脑啡肽类似物及其制备方法和应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL8005121A (nl) * | 1979-09-20 | 1981-03-24 | Erba Farmitalia | Biologisch actieve peptiden. |
JPH07503485A (ja) * | 1992-11-12 | 1995-04-13 | バイオメジャー インコーポレイテッド | オピオイドペプチド |
SE9300012D0 (sv) * | 1993-01-05 | 1993-01-05 | Astra Ab | New peptides |
-
1995
- 1995-02-13 IS IS4261A patent/IS4261A/is unknown
- 1995-02-15 EE EE9600071A patent/EE03265B1/et not_active IP Right Cessation
- 1995-02-15 AT AT95910838T patent/ATE217011T1/de not_active IP Right Cessation
- 1995-02-15 MX MX9603489A patent/MX9603489A/es unknown
- 1995-02-15 BR BR9506847A patent/BR9506847A/pt not_active Application Discontinuation
- 1995-02-15 WO PCT/SE1995/000158 patent/WO1995022557A1/en active IP Right Grant
- 1995-02-15 JP JP7521753A patent/JPH09509168A/ja not_active Abandoned
- 1995-02-15 DE DE69526577T patent/DE69526577T2/de not_active Expired - Fee Related
- 1995-02-15 PL PL95315947A patent/PL181092B1/pl unknown
- 1995-02-15 NZ NZ281742A patent/NZ281742A/en unknown
- 1995-02-15 ES ES95910838T patent/ES2176322T3/es not_active Expired - Lifetime
- 1995-02-15 CZ CZ19962391A patent/CZ288523B6/cs not_active IP Right Cessation
- 1995-02-15 HU HU9602281A patent/HUT74731A/hu unknown
- 1995-02-15 SK SK935-96A patent/SK93596A3/sk unknown
- 1995-02-15 CA CA002181367A patent/CA2181367A1/en not_active Abandoned
- 1995-02-15 EP EP95910838A patent/EP0746567B1/en not_active Expired - Lifetime
- 1995-02-16 TW TW084101429A patent/TW408131B/zh not_active IP Right Cessation
- 1995-07-19 HR HR9401519-5A patent/HRP950413A2/hr not_active Application Discontinuation
-
1996
- 1996-08-20 FI FI963252A patent/FI963252A0/fi unknown
- 1996-08-20 NO NO963464A patent/NO963464L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
FI963252A (fi) | 1996-08-20 |
CZ288523B6 (cs) | 2001-07-11 |
CA2181367A1 (en) | 1995-08-24 |
HUT74731A (en) | 1997-02-28 |
ES2176322T3 (es) | 2002-12-01 |
JPH09509168A (ja) | 1997-09-16 |
DE69526577D1 (de) | 2002-06-06 |
ATE217011T1 (de) | 2002-05-15 |
HRP950413A2 (en) | 1997-10-31 |
CZ239196A3 (en) | 1996-12-11 |
DE69526577T2 (de) | 2003-01-02 |
BR9506847A (pt) | 1997-09-30 |
AU690648B2 (en) | 1998-04-30 |
NZ281742A (en) | 1997-06-24 |
EP0746567B1 (en) | 2002-05-02 |
HU9602281D0 (en) | 1996-10-28 |
PL181092B1 (pl) | 2001-05-31 |
NO963464L (no) | 1996-08-20 |
PL315947A1 (en) | 1996-12-09 |
SK93596A3 (en) | 1997-05-07 |
IS4261A (is) | 1995-08-22 |
AU1865195A (en) | 1995-09-04 |
TW408131B (en) | 2000-10-11 |
MX9603489A (es) | 1997-03-29 |
EP0746567A1 (en) | 1996-12-11 |
WO1995022557A1 (en) | 1995-08-24 |
FI963252A0 (fi) | 1996-08-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapsed by not paying the annual fees |
Effective date: 20020215 |