ECSP14013192A - 3-(bifenil-3-il)-4-hidroxi-8-metoxi-1-azaespiro[4.5]dec-3-en-2-onas sustituidas - Google Patents

3-(bifenil-3-il)-4-hidroxi-8-metoxi-1-azaespiro[4.5]dec-3-en-2-onas sustituidas

Info

Publication number
ECSP14013192A
ECSP14013192A ECSP14013192A ECSP14013192A EC SP14013192 A ECSP14013192 A EC SP14013192A EC SP14013192 A ECSP14013192 A EC SP14013192A EC SP14013192 A ECSP14013192 A EC SP14013192A
Authority
EC
Ecuador
Prior art keywords
dec
substituted
bifenil
azaespiro
metoxi
Prior art date
Application number
Other languages
English (en)
Inventor
Reiner Fischer
Kai Thede
Ningshu Liu
Ulf Bömer
Ursula Mönning
Arne Scholz
Christoph-Stephan Hilger
Original Assignee
Bayer Ip Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ip Gmbh filed Critical Bayer Ip Gmbh
Publication of ECSP14013192A publication Critical patent/ECSP14013192A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/54—Spiro-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)

Abstract

Compuestos de 3-(bifenil-3-il)-4-hidroxi-8-metoxi-1-azaespiro[4.5]dec-3-en-2-onas sustituidas, en particular para fines terapéuticos, composiciones farmacéuticas y su uso en terapias, en particular para la profilaxis y terapia de trastornos neoplásicos.
ECSP14013192 2011-08-04 2014-02-04 3-(bifenil-3-il)-4-hidroxi-8-metoxi-1-azaespiro[4.5]dec-3-en-2-onas sustituidas ECSP14013192A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102011080406A DE102011080406A1 (de) 2011-08-04 2011-08-04 Substituierte 3-(Biphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro8[4.5]dec-3-en-2-one

Publications (1)

Publication Number Publication Date
ECSP14013192A true ECSP14013192A (es) 2014-03-31

Family

ID=46584054

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP14013192 ECSP14013192A (es) 2011-08-04 2014-02-04 3-(bifenil-3-il)-4-hidroxi-8-metoxi-1-azaespiro[4.5]dec-3-en-2-onas sustituidas

Country Status (21)

Country Link
US (1) US9278925B2 (es)
EP (1) EP2739607A1 (es)
JP (1) JP2014524413A (es)
KR (1) KR20140051378A (es)
CN (1) CN103842337A (es)
AP (1) AP2014007469A0 (es)
AU (1) AU2012292069A1 (es)
BR (1) BR112014002674A2 (es)
CA (1) CA2843809A1 (es)
CO (1) CO6870039A2 (es)
CR (1) CR20140063A (es)
CU (1) CU20140012A7 (es)
DE (1) DE102011080406A1 (es)
DO (1) DOP2014000022A (es)
EC (1) ECSP14013192A (es)
HK (1) HK1198167A1 (es)
IL (1) IL230609A0 (es)
MX (1) MX2014001393A (es)
SG (1) SG2014005235A (es)
TN (1) TN2014000046A1 (es)
WO (1) WO2013017600A1 (es)

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TWI579260B (zh) * 2012-03-28 2017-04-21 拜耳智慧財產有限公司 用於製備順式－烷氧基－取代之螺環狀苯基乙醯基胺基酸酯及順式－烷氧基－取代之螺環狀１ｈ－吡咯啶－２，４－二酮衍生物之方法
WO2015036892A1 (en) 2013-09-12 2015-03-19 Pfizer Inc. Use of acetyl-coa carboxylase inhibitors for treating acne vulgaris
JPWO2015056782A1 (ja) 2013-10-17 2017-03-09 塩野義製薬株式会社 新規アルキレン誘導体
EP3225618B1 (en) 2014-11-26 2020-05-06 Takeda Pharmaceutical Company Limited Bicyclic compound
WO2016159049A1 (ja) 2015-03-31 2016-10-06 武田薬品工業株式会社 単環式化合物
TWI767148B (zh) 2018-10-10 2022-06-11 美商弗瑪治療公司 抑制脂肪酸合成酶(fasn)
RU2733369C1 (ru) * 2020-01-15 2020-10-01 Федеральное государственное бюджетное учреждение науки Федеральный исследовательский центр "КОМИ научный центр Уральского отделения Российской академии наук" Хиральные трифторметилированные монотерпеновые тиоацетаты и тиолы пинанового ряда
RU2743302C1 (ru) * 2020-07-21 2021-02-16 Федеральное государственное бюджетное учреждение науки Федеральный исследовательский центр "КОМИ научный центр Уральского отделения Российской академии наук" Хиральные трифторметилированные монотерпеновые тиоацетаты и тиолы на основе миртеналя
CN118164897A (zh) * 2024-03-11 2024-06-11 南开大学 一种螺环特胺酸类化合物及其制备方法和应用

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Also Published As

Publication number Publication date
HK1198167A1 (es) 2015-03-13
CN103842337A (zh) 2014-06-04
AU2012292069A1 (en) 2014-02-13
EP2739607A1 (de) 2014-06-11
CR20140063A (es) 2014-03-19
TN2014000046A1 (en) 2015-07-01
BR112014002674A2 (pt) 2017-04-11
US9278925B2 (en) 2016-03-08
MX2014001393A (es) 2014-05-27
DOP2014000022A (es) 2014-03-31
US20140275199A1 (en) 2014-09-18
CU20140012A7 (es) 2014-05-27
IL230609A0 (en) 2014-03-31
DE102011080406A1 (de) 2013-02-07
CA2843809A1 (en) 2013-02-07
WO2013017600A1 (de) 2013-02-07
KR20140051378A (ko) 2014-04-30
AP2014007469A0 (en) 2014-02-28
JP2014524413A (ja) 2014-09-22
SG2014005235A (en) 2014-06-27
CO6870039A2 (es) 2014-02-20

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