ECSP11011004A - Proceso para la preparación de benzonorbornenos - Google Patents

Proceso para la preparación de benzonorbornenos

Info

Publication number
ECSP11011004A
ECSP11011004A EC2011011004A ECSP11011004A ECSP11011004A EC SP11011004 A ECSP11011004 A EC SP11011004A EC 2011011004 A EC2011011004 A EC 2011011004A EC SP11011004 A ECSP11011004 A EC SP11011004A EC SP11011004 A ECSP11011004 A EC SP11011004A
Authority
EC
Ecuador
Prior art keywords
compound
formula
chlorine
preparation
iii
Prior art date
Application number
EC2011011004A
Other languages
English (en)
Inventor
Harald Walter
Fanny Giordano
Denis Gribkov
Bjoern Antelmann
Mesmaeker Alain De
Original Assignee
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP08018721A external-priority patent/EP2181981A1/en
Application filed by Syngenta Participations Ag filed Critical Syngenta Participations Ag
Publication of ECSP11011004A publication Critical patent/ECSP11011004A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/30—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds
    • C07C209/32—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups
    • C07C209/36—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups by reduction of nitro groups bound to carbon atoms of six-membered aromatic rings in presence of hydrogen-containing gases and a catalyst
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/32—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by introduction of halogenated alkyl groups into ring compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/23—Preparation of halogenated hydrocarbons by dehalogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/25—Preparation of halogenated hydrocarbons by splitting-off hydrogen halides from halogenated hydrocarbons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
    • C07C17/266—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions of hydrocarbons and halogenated hydrocarbons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/06—Compounds containing nitro groups bound to a carbon skeleton having nitro groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/07—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C07C205/11—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/07—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C07C205/11—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings
    • C07C205/12—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings the six-membered aromatic ring or a condensed ring system containing that ring being substituted by halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/30—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds
    • C07C209/32—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups
    • C07C209/36—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups by reduction of nitro groups bound to carbon atoms of six-membered aromatic rings in presence of hydrogen-containing gases and a catalyst
    • C07C209/365—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups by reduction of nitro groups bound to carbon atoms of six-membered aromatic rings in presence of hydrogen-containing gases and a catalyst by reduction with preservation of halogen-atoms in compounds containing nitro groups and halogen atoms bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C211/57—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings being part of condensed ring systems of the carbon skeleton
    • C07C211/61—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings being part of condensed ring systems of the carbon skeleton with at least one of the condensed ring systems formed by three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C22/00—Cyclic compounds containing halogen atoms bound to an acyclic carbon atom
    • C07C22/02—Cyclic compounds containing halogen atoms bound to an acyclic carbon atom having unsaturation in the rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C22/00—Cyclic compounds containing halogen atoms bound to an acyclic carbon atom
    • C07C22/02—Cyclic compounds containing halogen atoms bound to an acyclic carbon atom having unsaturation in the rings
    • C07C22/04—Cyclic compounds containing halogen atoms bound to an acyclic carbon atom having unsaturation in the rings containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C23/00—Compounds containing at least one halogen atom bound to a ring other than a six-membered aromatic ring
    • C07C23/02—Monocyclic halogenated hydrocarbons
    • C07C23/08—Monocyclic halogenated hydrocarbons with a five-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/60—Ring systems containing bridged rings containing three rings containing at least one ring with less than six members
    • C07C2603/66—Ring systems containing bridged rings containing three rings containing at least one ring with less than six members containing five-membered rings

Abstract

La presente invención se refiere a un proceso novedoso para la preparación de 9-diclorometilen-1,2,3,4-tetrahidro-1,4-metano-naftalen-5-ilamina, proceso que comprendea) hacer reaccionar ciclopentadieno en presencia de un iniciador de radicales y CXCl3, donde X es cloro o bromo, para obtener un compuesto de Fórmula II(II), oaa) hacer reaccionar ciclopentadieno con CXCl3, donde X es cloro, en presencia de un catalizador metálico para obtener un compuesto de Fórmula II(II),donde X es cloro,b) hacer reaccionar el compuesto de Fórmula II con una base en presencia de un solvente apropiado para obtener el compuesto de Fórmula III(III),c) y convertir el compuesto de Fórmula III en presencia de 1,2-deshidro-6-nitrobenceno para obtener el compuesto de Fórmula IV(IV),y d) hidrogenar el compuesto de Fórmula IV en presencia de un catalizador metálico.
EC2011011004A 2008-10-27 2011-04-26 Proceso para la preparación de benzonorbornenos ECSP11011004A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08018721A EP2181981A1 (en) 2008-10-27 2008-10-27 Process for the preparation of benzonorbornenes
EP09161388 2009-05-28

Publications (1)

Publication Number Publication Date
ECSP11011004A true ECSP11011004A (es) 2011-05-31

Family

ID=41175685

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2011011004A ECSP11011004A (es) 2008-10-27 2011-04-26 Proceso para la preparación de benzonorbornenos

Country Status (24)

Country Link
US (3) US9115043B2 (es)
EP (1) EP2349975B1 (es)
JP (1) JP5406302B2 (es)
KR (1) KR101596814B1 (es)
CN (2) CN103319305B (es)
AR (1) AR075472A1 (es)
AU (1) AU2009309884B2 (es)
BR (1) BRPI0920833B1 (es)
CA (1) CA2739656C (es)
CO (1) CO6361987A2 (es)
CR (1) CR20110208A (es)
EA (1) EA019039B1 (es)
EC (1) ECSP11011004A (es)
EG (1) EG26332A (es)
ES (1) ES2431818T3 (es)
GE (1) GEP20135747B (es)
IL (1) IL211975A (es)
MX (1) MX2011003758A (es)
MY (1) MY150841A (es)
NZ (1) NZ591977A (es)
TW (1) TWI438176B (es)
UY (1) UY32195A (es)
WO (1) WO2010049228A1 (es)
ZA (1) ZA201102453B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011131546A1 (en) * 2010-04-20 2011-10-27 Syngenta Participations Ag Process for the preparation of pyrazole carboxylic acid amides
EP2433922A1 (en) 2010-08-25 2012-03-28 Syngenta Participations AG Process for the preparation of dichlorofulvene
TWI510472B (zh) * 2012-02-15 2015-12-01 Syngenta Participations Ag 立體選擇性製備吡唑羧醯胺之方法
US20200181091A1 (en) 2017-08-28 2020-06-11 Japan Finechem Company, Inc. Production method for pyrazole-4-carboxamide derivative
CN111454157B (zh) * 2020-05-14 2022-07-22 利民化学有限责任公司 一种3-硝基苯炔的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07291876A (ja) * 1994-03-03 1995-11-07 Ricoh Co Ltd シクロペンタジエン化合物及びそれを含有する電子写真感光体
JP4294129B2 (ja) * 1998-11-04 2009-07-08 旭化成ケミカルズ株式会社 シクロアルケンの塩素化法
CN101979375A (zh) * 2005-09-16 2011-02-23 先正达参股股份有限公司 酰胺的制备方法
UA87416C2 (ru) * 2005-10-25 2009-07-10 Syngenta Participations Ag Гетероциклические амиды, композиция на их основе и способ борьбы с заражением полезных растений фитопатогенными микроорганизмами и его предупреждение, промежуточные соединения
EP2316813B1 (en) 2005-12-12 2013-04-03 Syngenta Participations AG Process for the preparation of amines
DE602008003921D1 (de) * 2007-04-25 2011-01-20 Syngenta Participations Ag Fungizidzusammensetzungen

Also Published As

Publication number Publication date
CN103319305B (zh) 2015-04-08
TW201016642A (en) 2010-05-01
US20150141712A1 (en) 2015-05-21
CN103319305A (zh) 2013-09-25
KR101596814B1 (ko) 2016-02-23
EP2349975A1 (en) 2011-08-03
UY32195A (es) 2010-05-31
EP2349975B1 (en) 2013-07-31
BRPI0920833B1 (pt) 2018-02-06
US20180016211A1 (en) 2018-01-18
US9878970B1 (en) 2018-01-30
AR075472A1 (es) 2011-04-06
IL211975A (en) 2015-06-30
AU2009309884B2 (en) 2013-08-29
ZA201102453B (en) 2011-12-28
NZ591977A (en) 2012-08-31
CO6361987A2 (es) 2012-01-20
GEP20135747B (en) 2013-02-11
MX2011003758A (es) 2011-04-27
ES2431818T3 (es) 2013-11-28
WO2010049228A1 (en) 2010-05-06
CA2739656A1 (en) 2010-05-06
US9796646B2 (en) 2017-10-24
US9115043B2 (en) 2015-08-25
CA2739656C (en) 2016-08-16
AU2009309884A1 (en) 2010-05-06
CR20110208A (es) 2011-05-11
EA019039B1 (ru) 2013-12-30
IL211975A0 (en) 2011-06-30
TWI438176B (zh) 2014-05-21
CN102197016B (zh) 2013-12-18
JP5406302B2 (ja) 2014-02-05
BRPI0920833A2 (pt) 2015-12-22
KR20110074982A (ko) 2011-07-05
US20110207958A1 (en) 2011-08-25
EG26332A (en) 2013-08-19
MY150841A (en) 2014-02-28
JP2012506842A (ja) 2012-03-22
CN102197016A (zh) 2011-09-21
EA201100665A1 (ru) 2011-12-30

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