ECSP088531A - Vacuna terapéutica - Google Patents
Vacuna terapéuticaInfo
- Publication number
- ECSP088531A ECSP088531A EC2008008531A ECSP088531A ECSP088531A EC SP088531 A ECSP088531 A EC SP088531A EC 2008008531 A EC2008008531 A EC 2008008531A EC SP088531 A ECSP088531 A EC SP088531A EC SP088531 A ECSP088531 A EC SP088531A
- Authority
- EC
- Ecuador
- Prior art keywords
- amyloidosis
- diseases
- amyloid
- disorders
- compositions
- Prior art date
Links
- 229940021747 therapeutic vaccine Drugs 0.000 title 1
- 206010002022 amyloidosis Diseases 0.000 abstract 4
- 208000024827 Alzheimer disease Diseases 0.000 abstract 2
- 208000035474 group of disease Diseases 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 208000023769 AA amyloidosis Diseases 0.000 abstract 1
- 208000037259 Amyloid Plaque Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 208000025966 Neurological disease Diseases 0.000 abstract 1
- 206010039811 Secondary amyloidosis Diseases 0.000 abstract 1
- 208000010877 cognitive disease Diseases 0.000 abstract 1
- 230000001149 cognitive effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037765 diseases and disorders Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 208000027061 mild cognitive impairment Diseases 0.000 abstract 1
- 230000007505 plaque formation Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/812—Liposome comprising an antibody, antibody fragment, antigen, or other specific or nonspecific immunoeffector
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Ophthalmology & Optometry (AREA)
- Obesity (AREA)
- Psychology (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Zoology (AREA)
Abstract
La presente invención se refiere a métodos y composiciones para uso terapéutico y diagnóstico en el tratamiento de enfermedades y trastornos causados por o asociados con amiloide o proteínas símil amiloide incluso amiloidosis.En particular, la presente invención provee nuevos métodos y composiciones para generar una altamente específica y altamente efectiva respuesta inmune en un organismo, pero particularmente dentro de un animal, particularmente un mamífero o un humano, capaz de prevenir o aliviar amiloidosis, o los síntomas asociados con amiloidosis, un grupo de enfermedades y trastornos asociados con formación de placa amiloide incluso amiloidosis secundaria y amiloidosis relacionada con la edad avanzada incluso, sin limitaciones, trastornos neurológicos tales como enfermedad de Alzheimer (AD), incluso enfermedades o condiciones caracterizados por la pérdida de la capacidad de memoria cognitiva tales como, por ejemplo, deterioro cognitivo leve (MCI).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05027091 | 2005-12-12 | ||
EP06009098 | 2006-05-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP088531A true ECSP088531A (es) | 2008-07-30 |
Family
ID=37836865
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2008008531A ECSP088531A (es) | 2005-12-12 | 2008-06-12 | Vacuna terapéutica |
Country Status (24)
Country | Link |
---|---|
US (2) | US7807175B2 (es) |
EP (2) | EP2380588B1 (es) |
JP (2) | JP5249043B2 (es) |
KR (2) | KR101152557B1 (es) |
CN (1) | CN101330923B (es) |
AR (1) | AR058327A1 (es) |
AU (1) | AU2006326283B2 (es) |
BR (1) | BRPI0619747B8 (es) |
CA (1) | CA2633399C (es) |
CR (1) | CR9994A (es) |
DK (1) | DK1959991T3 (es) |
EC (1) | ECSP088531A (es) |
ES (2) | ES2551604T3 (es) |
HK (1) | HK1127486A1 (es) |
IL (1) | IL191397A (es) |
MA (1) | MA30252B1 (es) |
MY (1) | MY181173A (es) |
NO (1) | NO346055B1 (es) |
NZ (1) | NZ568384A (es) |
RU (2) | RU2440824C2 (es) |
SG (1) | SG172617A1 (es) |
TW (1) | TWI537000B (es) |
WO (1) | WO2007068411A2 (es) |
ZA (1) | ZA200804918B (es) |
Families Citing this family (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
KR20140087058A (ko) | 2005-11-30 | 2014-07-08 | 애브비 인코포레이티드 | 아밀로이드 베타 단백질에 대한 모노클로날 항체 및 이의 용도 |
AU2006319358B2 (en) | 2005-11-30 | 2012-01-19 | AbbVie Deutschland GmbH & Co. KG | Anti-Abeta globulomer antibodies, antigen-binding moieties thereof, corresponding hybridomas, nucleic acids, vectors, host cells, methods of producing said antibodies, compositions comprising said antibodies, uses of said antibodies and methods of using said antibodies |
CN101479381B (zh) | 2006-03-31 | 2015-04-29 | 中外制药株式会社 | 调控抗体血液动力学的方法 |
CN102838532A (zh) | 2006-11-24 | 2012-12-26 | Ac免疫有限公司 | 用于治疗与淀粉样物质或淀粉样蛋白有关的疾病的吡唑胺和噻唑胺衍生物 |
US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
EP2124952A2 (en) | 2007-02-27 | 2009-12-02 | Abbott GmbH & Co. KG | Method for the treatment of amyloidoses |
EP2481408A3 (en) | 2007-03-01 | 2013-01-09 | Probiodrug AG | New use of glutaminyl cyclase inhibitors |
EP2865670B1 (en) | 2007-04-18 | 2017-01-11 | Probiodrug AG | Thiourea derivatives as glutaminyl cyclase inhibitors |
US9096651B2 (en) | 2007-09-26 | 2015-08-04 | Chugai Seiyaku Kabushiki Kaisha | Method of modifying isoelectric point of antibody via amino acid substitution in CDR |
EP2106802A1 (en) | 2008-04-02 | 2009-10-07 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Modified peptides as synthetic vaccines in amyloid-associated disease |
CN103251948A (zh) | 2008-04-11 | 2013-08-21 | 中外制药株式会社 | 与多个分子的抗原反复结合的抗原结合分子 |
ES2866623T3 (es) | 2008-11-24 | 2021-10-19 | Massachusetts Inst Technology | Métodos y composiciones para el suministro localizado de nanopartículas a un tumor |
ES2885398T3 (es) * | 2009-03-18 | 2021-12-13 | Ac Immune Sa | Método para uso terapéutico |
UA107571C2 (xx) * | 2009-04-03 | 2015-01-26 | Фармацевтична композиція | |
KR100929372B1 (ko) * | 2009-05-22 | 2009-12-02 | 고려대학교 산학협력단 | 아밀로이드 베타 단편을 유효성분으로 포함하는 돌연변이 sod1에 의한 als 예방 및 치료용 조성물 |
AT508638B1 (de) * | 2009-08-21 | 2011-08-15 | Affiris Ag | Verwendung von peptiden und polypeptiden zur behandlung und/oder prävention von synukleinopathien |
EP2475428B1 (en) | 2009-09-11 | 2015-07-01 | Probiodrug AG | Heterocylcic derivatives as inhibitors of glutaminyl cyclase |
EP2311823A1 (en) | 2009-10-15 | 2011-04-20 | AC Immune S.A. | 2,6-Diaminopyridine compounds for treating diseases associated with amyloid proteins or for treating ocular diseases |
ES2586231T3 (es) | 2010-03-03 | 2016-10-13 | Probiodrug Ag | Inhibidores de glutaminil ciclasa |
CN102791704B (zh) | 2010-03-10 | 2015-11-25 | 前体生物药物股份公司 | 谷氨酰胺酰环化酶(qc, ec 2.3.2.5)的杂环抑制剂 |
AU2011227686B2 (en) | 2010-03-19 | 2014-12-04 | Massachusetts Institute Of Technology | Lipid vesicle compositions and methods of use |
US20110229556A1 (en) * | 2010-03-19 | 2011-09-22 | Massachusetts Institute Of Technology | Lipid-coated polymer particles for immune stimulation |
US9149432B2 (en) | 2010-03-19 | 2015-10-06 | Massachusetts Institute Of Technology | Lipid vesicle compositions and methods of use |
MX360403B (es) | 2010-04-15 | 2018-10-31 | Abbvie Inc | Proteinas de union a amiloide beta. |
ES2734552T3 (es) | 2010-04-16 | 2019-12-10 | Ac Immune Sa | Compuestos novedosos para el tratamiento de enfermedades asociadas a proteínas amiloides o de tipo amiloide |
EP2377860A1 (en) | 2010-04-16 | 2011-10-19 | AC Immune S.A. | Novel compounds for the treatment of diseases associated with amyloid or amyloid-like proteins |
EP2560953B1 (en) | 2010-04-21 | 2016-01-06 | Probiodrug AG | Inhibitors of glutaminyl cyclase |
US9289488B2 (en) | 2010-08-12 | 2016-03-22 | Ac Immune Sa | Vaccine engineering |
WO2012024187A1 (en) | 2010-08-14 | 2012-02-23 | Abbott Laboratories | Amyloid-beta binding proteins |
WO2012055933A1 (en) | 2010-10-26 | 2012-05-03 | Ac Immune S.A. | Liposome-based construct comprising a peptide modified through hydrophobic moieties |
CN107973851A (zh) | 2010-11-30 | 2018-05-01 | 中外制药株式会社 | 与多分子的抗原重复结合的抗原结合分子 |
US20120148542A1 (en) | 2010-12-10 | 2012-06-14 | Lifeline Scientific, Inc. | Machine perfusion with complement inhibitors |
US8530670B2 (en) | 2011-03-16 | 2013-09-10 | Probiodrug Ag | Inhibitors |
GB201113570D0 (en) | 2011-08-05 | 2011-09-21 | Glaxosmithkline Biolog Sa | Vaccine |
CA2811188C (en) * | 2011-09-23 | 2020-04-28 | Andrea Pfeifer | Vaccine therapy |
EP2834270B1 (en) | 2012-04-05 | 2019-10-30 | AC Immune S.A. | Humanized tau antibody |
JP6568514B2 (ja) | 2013-03-15 | 2019-08-28 | エーシー イミューン エス.エー. | 抗タウ抗体及び使用方法 |
CA3191031A1 (en) | 2013-09-27 | 2015-04-02 | Massachusetts Institute Of Technology | Carrier-free biologically-active protein nanostructures |
WO2015095780A1 (en) * | 2013-12-20 | 2015-06-25 | The University Of Kansas | Toll-like receptor 8 agonists |
PL3233921T3 (pl) * | 2014-12-19 | 2022-01-10 | Chugai Seiyaku Kabushiki Kaisha | Przeciwciała anty-c5 i sposoby ich stosowania |
CN116212048A (zh) | 2015-08-12 | 2023-06-06 | 麻省理工学院 | 纳米颗粒的细胞表面偶联 |
JP7185530B2 (ja) | 2016-06-13 | 2022-12-07 | トルク セラピューティクス, インコーポレイテッド | 免疫細胞機能を促進するための方法および組成物 |
RU2766112C2 (ru) | 2016-08-05 | 2022-02-08 | Чугаи Сейяку Кабусики Кайся | Композиция для профилактики или лечения связанных с il-8 заболеваний |
WO2018081085A1 (en) * | 2016-10-25 | 2018-05-03 | The Regents Of The University Of California | Methods of diagnosis and treatment of alzheimer's disease |
WO2018204302A1 (en) | 2017-05-01 | 2018-11-08 | Vanderbilt University | Phosphorylated hexaacyl disaccharides (phads) for treating or preventing infections |
KR20210032924A (ko) | 2017-09-05 | 2021-03-25 | 토크 테라퓨틱스, 인코포레이티드 | 치료용 단백질 조성물 및 그의 제조 및 사용 방법 |
PL3461819T3 (pl) | 2017-09-29 | 2020-11-30 | Probiodrug Ag | Inhibitory cyklazy glutaminylowej |
US11124552B2 (en) | 2017-10-25 | 2021-09-21 | Ac Immune Sa | Compositions of phosphorylated tau peptides and uses thereof |
CN108037277A (zh) * | 2017-12-07 | 2018-05-15 | 中国兽医药品监察所 | 一种区分牛布鲁氏菌疫苗免疫与自然感染状态的方法 |
CN112165956A (zh) * | 2018-04-10 | 2021-01-01 | Ac免疫有限公司 | 抗Aβ治疗性疫苗 |
BR112020020660A2 (pt) | 2018-04-10 | 2021-03-02 | Ac Immune Sa | vacinas terapêuticas anti-abeta |
BR112021014794A2 (pt) | 2019-02-08 | 2021-10-05 | Ac Immune S.A. | Método de administração segura de vacina de peptídeo de tau fosforilada |
KR20220005033A (ko) | 2019-04-24 | 2022-01-12 | 얀센 파마슈티칼즈, 인코포레이티드 | 타우 백신의 이종 투여 |
BR112021023209A2 (pt) | 2019-05-21 | 2022-01-18 | Ac Immune Sa | Terapia com vacina anti-abeta |
WO2021207303A1 (en) * | 2020-04-07 | 2021-10-14 | Alsatech, Inc. | Immune stimulation against coronavirus infections |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4847082A (en) | 1987-01-21 | 1989-07-11 | Robert Sabin | Method of treatment of Alzheimer's disease using phytic acid |
US5262332A (en) * | 1989-04-05 | 1993-11-16 | Brigham And Women's Hospital | Diagnostic method for Alzheimer's disease: examination of non-neural tissue |
US6787523B1 (en) * | 1997-12-02 | 2004-09-07 | Neuralab Limited | Prevention and treatment of amyloidogenic disease |
EP1235587A2 (en) * | 1999-11-29 | 2002-09-04 | Neurochem, Inc. | Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases comprising all-d peptides |
DE10003992A1 (de) * | 2000-01-29 | 2001-08-09 | Bosch Gmbh Robert | Sensoranordnung |
CA2421374C (en) * | 2000-09-06 | 2017-03-07 | Aventis Pharma S.A. | Methods and compositions for diseases associated with amyloidosis |
EP1203614A1 (de) | 2000-11-03 | 2002-05-08 | Polymun Scientific Immunbiologische Forschung GmbH | Verfahren und Vorrichtung zur Herstellung von Lipidvesikeln |
US6906169B2 (en) * | 2001-05-25 | 2005-06-14 | United Biomedical, Inc. | Immunogenic peptide composition comprising measles virus Fprotein Thelper cell epitope (MUFThl-16) and N-terminus of β-amyloid peptide |
US7084115B2 (en) * | 2002-04-29 | 2006-08-01 | Oxyplus, Inc. | Inositol pyrophosphates, and methods of use thereof |
EP1585520A1 (en) | 2002-12-24 | 2005-10-19 | Neurochem (International) Limited | Therapeutic formulations for the treatment of beta-amyloid related diseases |
US7521481B2 (en) * | 2003-02-27 | 2009-04-21 | Mclaurin Joanne | Methods of preventing, treating and diagnosing disorders of protein aggregation |
JP4772667B2 (ja) * | 2003-06-02 | 2011-09-14 | エヴォルーテック・リミテッド | 補体阻害剤 |
US20050123553A1 (en) * | 2003-07-30 | 2005-06-09 | Alon Monsonego | Amyloid beta-peptide and methods of use |
JP2008524247A (ja) * | 2004-12-15 | 2008-07-10 | エラン ファーマ インターナショナル リミテッド | 認知の改善における使用のためのアミロイドβ抗体 |
EP1676859A1 (en) * | 2004-12-30 | 2006-07-05 | Pevion Biotech Ltd. | Immunogenic compositions of cyclic peptides derived from the beta-amyloid peptide |
SG10201404801YA (en) * | 2005-12-12 | 2014-09-26 | Ac Immune Sa | Monoclonal antibody |
-
2006
- 2006-12-08 CA CA2633399A patent/CA2633399C/en active Active
- 2006-12-08 DK DK06829455.2T patent/DK1959991T3/da active
- 2006-12-08 NZ NZ568384A patent/NZ568384A/en unknown
- 2006-12-08 KR KR1020087017128A patent/KR101152557B1/ko active IP Right Grant
- 2006-12-08 EP EP11172818.4A patent/EP2380588B1/en active Active
- 2006-12-08 ES ES11172818.4T patent/ES2551604T3/es active Active
- 2006-12-08 CN CN200680046697.XA patent/CN101330923B/zh active Active
- 2006-12-08 MY MYPI20081951A patent/MY181173A/en unknown
- 2006-12-08 AU AU2006326283A patent/AU2006326283B2/en active Active
- 2006-12-08 RU RU2008128133/15A patent/RU2440824C2/ru active
- 2006-12-08 WO PCT/EP2006/011861 patent/WO2007068411A2/en active Application Filing
- 2006-12-08 SG SG2011036969A patent/SG172617A1/en unknown
- 2006-12-08 JP JP2008544833A patent/JP5249043B2/ja active Active
- 2006-12-08 BR BRPI0619747A patent/BRPI0619747B8/pt active IP Right Grant
- 2006-12-08 EP EP06829455A patent/EP1959991B1/en active Active
- 2006-12-08 NO NO20082216A patent/NO346055B1/no unknown
- 2006-12-08 ES ES06829455T patent/ES2407429T3/es active Active
- 2006-12-08 KR KR1020127002472A patent/KR101236611B1/ko active IP Right Grant
- 2006-12-12 US US11/637,607 patent/US7807175B2/en active Active
- 2006-12-12 AR ARP060105476A patent/AR058327A1/es not_active Application Discontinuation
- 2006-12-12 TW TW095146547A patent/TWI537000B/zh active
-
2008
- 2008-05-13 IL IL191397A patent/IL191397A/en active IP Right Grant
- 2008-05-20 CR CR9994A patent/CR9994A/es not_active Application Discontinuation
- 2008-06-05 ZA ZA2008/04918A patent/ZA200804918B/en unknown
- 2008-06-12 EC EC2008008531A patent/ECSP088531A/es unknown
- 2008-07-11 MA MA31115A patent/MA30252B1/fr unknown
-
2009
- 2009-04-14 US US12/386,140 patent/US8603487B2/en active Active
- 2009-06-09 HK HK09105160.4A patent/HK1127486A1/xx unknown
-
2011
- 2011-10-12 RU RU2011141308/15A patent/RU2011141308A/ru not_active Application Discontinuation
-
2013
- 2013-02-13 JP JP2013025108A patent/JP2013126993A/ja not_active Withdrawn
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ECSP088531A (es) | Vacuna terapéutica | |
AR058326A1 (es) | Anticuerpo monoclonal | |
MX2011010353A (es) | Composicion farmaceutica. | |
SV2008002511A (es) | Anticuerpos dirigidos contra el peptido amiloide beta y metodos que utilizan los mismos | |
MX2009003468A (es) | Anticuerpo humanizado contra beta amiloide. | |
UY27003A1 (es) | Productos radiofarmacéuticos para el diagnóstico de la enfermedad de alzheimer | |
MX2009013503A (es) | Anticuerpo monoclonal anti-amiloide-beta. | |
NI201100100A (es) | Moduladores de aril metil benzoquinazolinona alostéricos positivos del receptor m1. | |
MY164376A (en) | Phosphospecific antibodies recognizing tau | |
UY33277A (es) | Compuestos de anillo espiro-tetraciclico como moduladores de beta-secretasa y métodos de uso | |
MX354662B (es) | Anticuerpos fosfoespecificos que reconocen la tau. | |
BR112014006376A2 (pt) | terapia baseada em proteínas e diagnóstico de patologia mediada por tau em doença de alzheimer | |
EA200700427A1 (ru) | Предупреждение и лечение синуклеинопатических и амилоидогенных заболеваний | |
WO2008060364A3 (en) | Humani zed antibody against amyloid beta | |
CL2011002766A1 (es) | Compuestos derivados de carboxamida, inhibidores de calpaina; composicion farmaceutica que los comprende; y su uso en el tratamiento de enfermedades neurodegenerativas, alzahimer, dolor, entre otras. | |
ATE530544T1 (de) | Benzyl-substituierte positive allosterische chinolon-m1-rezeptormodulatoren | |
EA201170190A1 (ru) | Фармацевтическая композиция, содержащая экстракт мозга свиньи | |
BRPI0407693A (pt) | uso de esteróides para preparação de formulações utilizáveis no tratamento de pessoas sofrendo de distúrbios oculares, bem como formulação assim obtidos | |
CR20140496A (es) | Anticuerpos humanizados contra beta-amiloides | |
EA201591021A1 (ru) | 4-гидрокси-2-метил-5-(пропан-2-илиден)циклогекс-3-энекарбальдегид в профилактике и лечении когнитивных, нейродегенеративных или нейронных заболеваний | |
EA201171352A1 (ru) | Антигенсвязывающие фрагменты антитела и их применение для лечения или диагностики глазных болезней | |
WO2008070284A3 (en) | Amyloid beta peptides and methods of uses thereof | |
EP2404612A8 (en) | Diagnosis, prophylaxis and therapy of Alzheimer's disease and other neurodementing disorders | |
WO2009120659A3 (en) | Human monoclonal antibodies against amyloid beta protein, and their use as therapeutic agents | |
ECSP066772A (es) | Compuestos de pirazolina sustituidos para reducir trigliceridos en la sangre |