ECSP088499A - Nuevos compuestos de 2-amino-imidazol-4-ona y su uso en la fabricación de un medicamento para uso en el tratamiento de alteración cognitiva, enfermedad de alzheimer, neurodegeneración y demencia - Google Patents

Nuevos compuestos de 2-amino-imidazol-4-ona y su uso en la fabricación de un medicamento para uso en el tratamiento de alteración cognitiva, enfermedad de alzheimer, neurodegeneración y demencia

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Publication number
ECSP088499A
ECSP088499A EC2008008499A ECSP088499A ECSP088499A EC SP088499 A ECSP088499 A EC SP088499A EC 2008008499 A EC2008008499 A EC 2008008499A EC SP088499 A ECSP088499 A EC SP088499A EC SP088499 A ECSP088499 A EC SP088499A
Authority
EC
Ecuador
Prior art keywords
new compounds
neurodegeneration
dementia
alzheimer
disease
Prior art date
Application number
EC2008008499A
Other languages
English (en)
Inventor
Jeremy Burrows
Stefan Berg
Sven Hellberg
Christopher William Murray
Gianni Chessari
Miles Stuart Congreve
Johan Hedstroem
Katharina Hoegdin
Jacob Kihlstroem
Karin Kolmodin
Johan Lindstroem
Sahil Patel
Original Assignee
Astrazeneca Ab
Astex Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38049092&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP088499(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab, Astex Therapeutics Ltd filed Critical Astrazeneca Ab
Publication of ECSP088499A publication Critical patent/ECSP088499A/es

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    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88—Nitrogen atoms, e.g. allantoin
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    • A61K31/4164—1,3-Diazoles
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Abstract

Esta invención se refiere a nuevos compuestos que tienen la fórmula estructural I indicada más abajo; y a su sal farmacéuticamente aceptable, composiciones y métodos de uso. Estos nuevos compuestos proveen un tratamiento o profilaxis de la alteración cognitiva, Enfermedad de Alzheimer, neurodegeneración y demencia
EC2008008499A 2005-11-21 2008-06-03 Nuevos compuestos de 2-amino-imidazol-4-ona y su uso en la fabricación de un medicamento para uso en el tratamiento de alteración cognitiva, enfermedad de alzheimer, neurodegeneración y demencia ECSP088499A (es)

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AR057984A1 (es) 2008-01-09
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BRPI0618845A2 (pt) 2016-09-13
US20080293718A1 (en) 2008-11-27
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