EA202290017A1 - Фармацевтическая комбинация, содержащая селективный агонист рецептора s1p1 - Google Patents

Фармацевтическая комбинация, содержащая селективный агонист рецептора s1p1

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Publication number
EA202290017A1
EA202290017A1 EA202290017A EA202290017A EA202290017A1 EA 202290017 A1 EA202290017 A1 EA 202290017A1 EA 202290017 A EA202290017 A EA 202290017A EA 202290017 A EA202290017 A EA 202290017A EA 202290017 A1 EA202290017 A1 EA 202290017A1
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Eurasian Patent Office
Prior art keywords
pharmaceutical combination
combination containing
selective agonist
receptor selective
dioate
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EA202290017A
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English (en)
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Мартин Клозель
Лука Пиали
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Актелион Фармасьютиклз Лтд
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Publication of EA202290017A1 publication Critical patent/EA202290017A1/ru

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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
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    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
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  • Urology & Nephrology (AREA)
  • Transplantation (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
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Abstract

Изобретение относится к фармацевтической комбинации, содержащей первый активный ингредиент, которым является (R)-5-[3-хлор-4-(2,3-дигидроксипропокси)бенз[Z]илиден]-2-([Z]-пропилимино)-3-o-толилтиазолидин-4-он или его фармацевтически приемлемая соль, и второй активный ингредиент, который выбран из группы, включающей метилфумарат, диметилфумарат, (N,N-диэтилкарбамоил)метилметил-(2E)бут-2-ен-1,4-диоат и 2-(2,5-диоксопирролидин-1-ил)этилметил-(2E)бут-2-ен-1,4-диоат или его фармацевтически приемлемую соль.
EA202290017A 2014-12-11 2015-12-10 Фармацевтическая комбинация, содержащая селективный агонист рецептора s1p1 EA202290017A1 (ru)

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Application Number Priority Date Filing Date Title
EP2014077469 2014-12-11

Publications (1)

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EA202290017A1 true EA202290017A1 (ru) 2022-03-22

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EA201791260A EA039629B1 (ru) 2014-12-11 2015-12-10 Фармацевтическая комбинация, содержащая селективный агонист рецептора s1p1
EA202290017A EA202290017A1 (ru) 2014-12-11 2015-12-10 Фармацевтическая комбинация, содержащая селективный агонист рецептора s1p1

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US (5) US10245253B2 (ru)
EP (1) EP3229794A1 (ru)
JP (3) JP6437119B2 (ru)
KR (3) KR101996245B1 (ru)
CN (1) CN106999462B (ru)
AU (1) AU2015359306B2 (ru)
BR (1) BR112017012396B1 (ru)
CA (1) CA2964616C (ru)
CL (1) CL2017001479A1 (ru)
EA (2) EA039629B1 (ru)
HK (1) HK1245106A1 (ru)
IL (2) IL252701B (ru)
MA (2) MA41139A (ru)
MX (2) MX2017007651A (ru)
PH (1) PH12017501060B1 (ru)
SA (1) SA517381489B1 (ru)
SG (1) SG11201704569SA (ru)
UA (1) UA122063C2 (ru)
WO (1) WO2016092042A1 (ru)

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