EA202091506A1 - Триазол n-связанные карбамоил циклогексильные кислоты в качестве антагонистов lpa - Google Patents

Триазол n-связанные карбамоил циклогексильные кислоты в качестве антагонистов lpa

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Publication number
EA202091506A1
EA202091506A1 EA202091506A EA202091506A EA202091506A1 EA 202091506 A1 EA202091506 A1 EA 202091506A1 EA 202091506 A EA202091506 A EA 202091506A EA 202091506 A EA202091506 A EA 202091506A EA 202091506 A1 EA202091506 A1 EA 202091506A1
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EA
Eurasian Patent Office
Prior art keywords
triazole
bonded
cyclohexyl acids
lpa antagonists
carbamoyl
Prior art date
Application number
EA202091506A
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English (en)
Inventor
Янь Ши
Питер Тай Вах Ченг
Йинь Ван
Джун Ши
Шивэй Tao
Джун Ли
Лоурэнс Дж. Кеннеди
Роберт Ф. Кальтенбах III
Хао Чжанг
Джеймс Р. Корте
Original Assignee
Бристол-Маерс Сквибб Компани
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Publication of EA202091506A1 publication Critical patent/EA202091506A1/ru

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Abstract

В настоящем изобретении предлагаются соединения формулы (I)или их стереоизомеры, таутомеры или фармацевтически приемлемые соли или сольваты, где все переменные являются такими, как определено в настоящем документе. Эти соединения являются селективными ингибиторами рецептора LPA.
EA202091506A 2017-12-19 2018-12-18 Триазол n-связанные карбамоил циклогексильные кислоты в качестве антагонистов lpa EA202091506A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762607399P 2017-12-19 2017-12-19
PCT/US2018/066117 WO2019126090A1 (en) 2017-12-19 2018-12-18 Triazole n-linked carbamoyl cyclohexyl acids as lpa antagonists

Publications (1)

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EA202091506A1 true EA202091506A1 (ru) 2020-09-22

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US (4) US10662172B2 (ru)
EP (2) EP3710438B1 (ru)
JP (1) JP7274486B6 (ru)
KR (1) KR20200100721A (ru)
CN (2) CN112521368B (ru)
AR (1) AR113964A1 (ru)
AU (1) AU2018392321B2 (ru)
BR (1) BR112020011776A2 (ru)
CA (1) CA3085586A1 (ru)
CL (1) CL2020001547A1 (ru)
CY (1) CY1124863T1 (ru)
DK (1) DK3710438T3 (ru)
EA (1) EA202091506A1 (ru)
ES (1) ES2898364T3 (ru)
HR (1) HRP20211918T8 (ru)
HU (1) HUE057366T2 (ru)
IL (1) IL275348B2 (ru)
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PL (1) PL3710438T3 (ru)
PT (1) PT3710438T (ru)
RS (1) RS62710B1 (ru)
SG (1) SG11202005699QA (ru)
SI (1) SI3710438T1 (ru)
TW (1) TWI830713B (ru)
WO (1) WO2019126090A1 (ru)

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