EA201791596A1 - Пиразоловые соединения - Google Patents

Пиразоловые соединения

Info

Publication number
EA201791596A1
EA201791596A1 EA201791596A EA201791596A EA201791596A1 EA 201791596 A1 EA201791596 A1 EA 201791596A1 EA 201791596 A EA201791596 A EA 201791596A EA 201791596 A EA201791596 A EA 201791596A EA 201791596 A1 EA201791596 A1 EA 201791596A1
Authority
EA
Eurasian Patent Office
Prior art keywords
pyrazol compounds
compounds
pyrazol
formula
pharmaceutically acceptable
Prior art date
Application number
EA201791596A
Other languages
English (en)
Inventor
Кок Кан Хо
Вэйцян Чжань
Цзине Чжоу
Original Assignee
Эли Лилли Энд Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эли Лилли Энд Компани filed Critical Эли Лилли Энд Компани
Publication of EA201791596A1 publication Critical patent/EA201791596A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

В настоящем изобретении предложены соединения формулыили их фармацевтически приемлемые соли.
EA201791596A 2015-02-18 2016-02-11 Пиразоловые соединения EA201791596A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/CN2015/073236 WO2016131198A1 (en) 2015-02-18 2015-02-18 Pyrazole compounds
PCT/US2016/017466 WO2016133770A1 (en) 2015-02-18 2016-02-11 Pyrazole compounds

Publications (1)

Publication Number Publication Date
EA201791596A1 true EA201791596A1 (ru) 2017-12-29

Family

ID=55487101

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201791596A EA201791596A1 (ru) 2015-02-18 2016-02-11 Пиразоловые соединения

Country Status (12)

Country Link
US (1) US9822101B1 (ru)
EP (1) EP3259266A1 (ru)
JP (1) JP2018505897A (ru)
KR (1) KR20170102360A (ru)
CN (1) CN107257794B (ru)
AU (1) AU2016220315A1 (ru)
BR (1) BR112017014281A2 (ru)
CA (1) CA2972994A1 (ru)
EA (1) EA201791596A1 (ru)
IL (1) IL253147A0 (ru)
MX (1) MX2017010571A (ru)
WO (2) WO2016131198A1 (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019173505A1 (en) * 2018-03-06 2019-09-12 Zafgen, Inc. Methods of treating disorders related to glycemic control

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030220371A1 (en) * 2000-04-12 2003-11-27 Kallander Lara S. Compounds and methods
EP2019677B1 (en) * 2006-05-16 2013-08-14 Merck Sharp & Dohme Corp. Aminotetrahydropyrans as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
WO2010065879A2 (en) 2008-12-04 2010-06-10 Zafgen Corporation Methods of treating an overweight or obese subject
GB0904285D0 (en) * 2009-03-12 2009-04-22 Prosidion Ltd Compounds for the treatment of metabolic disorders
TW201209054A (en) * 2010-05-28 2012-03-01 Prosidion Ltd Novel compounds
CN103626775B (zh) * 2013-12-02 2015-05-20 南京华威医药科技开发有限公司 具有二嗪结构的dpp-4抑制剂
WO2015089800A1 (en) 2013-12-19 2015-06-25 Eli Lilly And Company Fluorophenyl pyrazol compounds

Also Published As

Publication number Publication date
US20170334885A1 (en) 2017-11-23
MX2017010571A (es) 2017-12-07
WO2016133770A1 (en) 2016-08-25
BR112017014281A2 (pt) 2018-01-02
KR20170102360A (ko) 2017-09-08
IL253147A0 (en) 2017-08-31
JP2018505897A (ja) 2018-03-01
WO2016131198A1 (en) 2016-08-25
CA2972994A1 (en) 2016-08-25
CN107257794A (zh) 2017-10-17
CN107257794B (zh) 2019-10-18
AU2016220315A1 (en) 2017-07-13
EP3259266A1 (en) 2017-12-27
US9822101B1 (en) 2017-11-21

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