EA202090500A1 - Кристаллические формы иммуномодуляторов - Google Patents
Кристаллические формы иммуномодуляторовInfo
- Publication number
- EA202090500A1 EA202090500A1 EA202090500A EA202090500A EA202090500A1 EA 202090500 A1 EA202090500 A1 EA 202090500A1 EA 202090500 A EA202090500 A EA 202090500A EA 202090500 A EA202090500 A EA 202090500A EA 202090500 A1 EA202090500 A1 EA 202090500A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- crystalline forms
- immunomodulators
- compounds
- relates
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
Abstract
Настоящее изобретение относится к кристаллическим формам соединения 3-замещенного 1,2,4-оксадиазола, включая безводную кристаллическую форму, способам получения указанных соединений и связанных фармацевтических препаратов указанных соединений. Настоящее изобретение также относится к препаратам, подходящим для фармацевтических, ветеринарных и сельскохозяйственных применений.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/CN2017/104485 WO2019061324A1 (en) | 2017-09-29 | 2017-09-29 | CRYSTALLINE FORMS OF IMMUNOMODULATORS |
PCT/US2018/053052 WO2019067678A1 (en) | 2017-09-29 | 2018-09-27 | CRYSTALLINE FORMS OF IMMUNOMODULATORS |
Publications (1)
Publication Number | Publication Date |
---|---|
EA202090500A1 true EA202090500A1 (ru) | 2020-11-03 |
Family
ID=65900346
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA202090500A EA202090500A1 (ru) | 2017-09-29 | 2018-09-27 | Кристаллические формы иммуномодуляторов |
Country Status (13)
Country | Link |
---|---|
US (3) | US11040948B2 (ru) |
EP (1) | EP3687534A4 (ru) |
JP (2) | JP2021501127A (ru) |
KR (1) | KR20200060402A (ru) |
CN (2) | CN111163772A (ru) |
AU (2) | AU2018341583B2 (ru) |
BR (1) | BR112020006137A2 (ru) |
CA (1) | CA3076013A1 (ru) |
EA (1) | EA202090500A1 (ru) |
IL (1) | IL273463A (ru) |
PH (1) | PH12020550133A1 (ru) |
SG (1) | SG11202002378XA (ru) |
WO (2) | WO2019061324A1 (ru) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6521977B2 (ja) | 2013-09-06 | 2019-05-29 | オーリジーン ディスカバリー テクノロジーズ リミテッドAurigene Discovery Technologies Limited | 免疫調節剤としての1,2,4−オキサジアゾール誘導体 |
HUE058274T2 (hu) | 2015-03-10 | 2022-07-28 | Aurigene Discovery Tech Ltd | 1,2,4-oxadiazol és tiadiazol-vegyületek, mint immunmodulátorok |
WO2019061324A1 (en) | 2017-09-29 | 2019-04-04 | Curis Inc. | CRYSTALLINE FORMS OF IMMUNOMODULATORS |
EA202090536A1 (ru) | 2017-10-11 | 2020-07-22 | Ориджен Дискавери Текнолоджис Лимитед | Кристаллические формы 3-замещенного 1,2,4-оксадиазола |
KR20200083503A (ko) | 2017-11-03 | 2020-07-08 | 오리진 디스커버리 테크놀로지스 리미티드 | Tim-3 경로와 pd-1 경로의 이중 저해제 |
EA202090749A1 (ru) | 2017-11-06 | 2020-08-19 | Ориджен Дискавери Текнолоджис Лимитед | Способы совместной терапии для иммуномодуляции |
US11111735B2 (en) | 2018-12-20 | 2021-09-07 | Impact Selector International, Llc | Downhole tool for connecting with a conveyance line |
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WO2019061324A1 (en) | 2017-09-29 | 2019-04-04 | Curis Inc. | CRYSTALLINE FORMS OF IMMUNOMODULATORS |
EA202090536A1 (ru) | 2017-10-11 | 2020-07-22 | Ориджен Дискавери Текнолоджис Лимитед | Кристаллические формы 3-замещенного 1,2,4-оксадиазола |
KR20200083503A (ko) | 2017-11-03 | 2020-07-08 | 오리진 디스커버리 테크놀로지스 리미티드 | Tim-3 경로와 pd-1 경로의 이중 저해제 |
EA202090749A1 (ru) | 2017-11-06 | 2020-08-19 | Ориджен Дискавери Текнолоджис Лимитед | Способы совместной терапии для иммуномодуляции |
-
2017
- 2017-09-29 WO PCT/CN2017/104485 patent/WO2019061324A1/en active Application Filing
-
2018
- 2018-09-27 CN CN201880063100.5A patent/CN111163772A/zh active Pending
- 2018-09-27 BR BR112020006137-9A patent/BR112020006137A2/pt unknown
- 2018-09-27 JP JP2020517332A patent/JP2021501127A/ja active Pending
- 2018-09-27 SG SG11202002378XA patent/SG11202002378XA/en unknown
- 2018-09-27 WO PCT/US2018/053052 patent/WO2019067678A1/en active Application Filing
- 2018-09-27 KR KR1020207009251A patent/KR20200060402A/ko not_active Application Discontinuation
- 2018-09-27 EA EA202090500A patent/EA202090500A1/ru unknown
- 2018-09-27 CA CA3076013A patent/CA3076013A1/en active Pending
- 2018-09-27 EP EP18863750.8A patent/EP3687534A4/en active Pending
- 2018-09-27 AU AU2018341583A patent/AU2018341583B2/en active Active
- 2018-09-27 CN CN202311171278.0A patent/CN117209444A/zh active Pending
- 2018-09-27 US US16/651,830 patent/US11040948B2/en active Active
-
2020
- 2020-03-19 IL IL273463A patent/IL273463A/en unknown
- 2020-03-25 PH PH12020550133A patent/PH12020550133A1/en unknown
-
2021
- 2021-06-17 US US17/350,445 patent/US11643401B2/en active Active
-
2023
- 2023-01-25 US US18/101,387 patent/US11939306B2/en active Active
- 2023-06-30 JP JP2023108094A patent/JP2023134541A/ja active Pending
-
2024
- 2024-03-26 AU AU2024201938A patent/AU2024201938A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US20230167077A1 (en) | 2023-06-01 |
BR112020006137A2 (pt) | 2020-10-13 |
SG11202002378XA (en) | 2020-04-29 |
AU2018341583A1 (en) | 2020-04-02 |
US11643401B2 (en) | 2023-05-09 |
CN117209444A (zh) | 2023-12-12 |
CA3076013A1 (en) | 2019-04-04 |
AU2018341583B2 (en) | 2024-04-04 |
US11040948B2 (en) | 2021-06-22 |
AU2024201938A1 (en) | 2024-04-11 |
US20200247766A1 (en) | 2020-08-06 |
EP3687534A1 (en) | 2020-08-05 |
PH12020550133A1 (en) | 2021-02-08 |
JP2023134541A (ja) | 2023-09-27 |
US20210380544A1 (en) | 2021-12-09 |
KR20200060402A (ko) | 2020-05-29 |
EP3687534A4 (en) | 2021-06-30 |
WO2019061324A1 (en) | 2019-04-04 |
WO2019067678A1 (en) | 2019-04-04 |
IL273463A (en) | 2020-05-31 |
CN111163772A (zh) | 2020-05-15 |
US11939306B2 (en) | 2024-03-26 |
JP2021501127A (ja) | 2021-01-14 |
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