EA202090276A1 - Фармацевтическая композиция для лечения анемии - Google Patents

Фармацевтическая композиция для лечения анемии

Info

Publication number
EA202090276A1
EA202090276A1 EA202090276A EA202090276A EA202090276A1 EA 202090276 A1 EA202090276 A1 EA 202090276A1 EA 202090276 A EA202090276 A EA 202090276A EA 202090276 A EA202090276 A EA 202090276A EA 202090276 A1 EA202090276 A1 EA 202090276A1
Authority
EA
Eurasian Patent Office
Prior art keywords
pharmaceutical composition
anemia
treatment
preparation
relates
Prior art date
Application number
EA202090276A
Other languages
English (en)
Inventor
Анкит Шиам Сингх
Ведпракаш Мишра
Неелима Тонгра
Original Assignee
Фримлайн Прайвет Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Фримлайн Прайвет Лимитед filed Critical Фримлайн Прайвет Лимитед
Publication of EA202090276A1 publication Critical patent/EA202090276A1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/40Transferrins, e.g. lactoferrins, ovotransferrins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16Inorganic salts, minerals or trace elements
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/18Peptides; Protein hydrolysates
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/19Dairy proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07Retinol compounds, e.g. vitamin A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/375Ascorbic acid, i.e. vitamin C; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A61K31/708Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid having oxo groups directly attached to the purine ring system, e.g. guanosine, guanylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846Poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Настоящее изобретение относится к фармацевтической композиции/препарату для применения при лечении железодефицитной анемии (IDA), анемии воспаления (AOI) и нейродегенеративных заболеваний. Более конкретно, изобретение относится к фармацевтической композиции/препарату, содержащей синергетическую комбинацию лактоферрина и гуанозиновых нуклеотидов или их фармацевтически приемлемой соли. В заявке также представлены различные лекарственные формы и способы их получения.
EA202090276A 2018-03-09 2019-03-04 Фармацевтическая композиция для лечения анемии EA202090276A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN201821008809 2018-03-09
PCT/IB2019/051706 WO2019171236A1 (en) 2018-03-09 2019-03-04 A pharmaceutical composition for anaemia

Publications (1)

Publication Number Publication Date
EA202090276A1 true EA202090276A1 (ru) 2020-11-16

Family

ID=66397286

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202090276A EA202090276A1 (ru) 2018-03-09 2019-03-04 Фармацевтическая композиция для лечения анемии

Country Status (24)

Country Link
US (1) US12016906B2 (ru)
EP (1) EP3661373B1 (ru)
AU (1) AU2019232621B2 (ru)
BR (1) BR112020018319A2 (ru)
CA (1) CA3073184C (ru)
CO (1) CO2020010193A2 (ru)
DK (1) DK3661373T3 (ru)
EA (1) EA202090276A1 (ru)
ES (1) ES2927216T3 (ru)
HR (1) HRP20221105T1 (ru)
HU (1) HUE059584T2 (ru)
LT (1) LT3661373T (ru)
MA (1) MA52154B1 (ru)
MD (1) MD3661373T2 (ru)
MY (1) MY183462A (ru)
PE (1) PE20201278A1 (ru)
PH (1) PH12019550263A1 (ru)
PL (1) PL3661373T3 (ru)
PT (1) PT3661373T (ru)
RS (1) RS63563B1 (ru)
SG (1) SG11202008732VA (ru)
SI (1) SI3661373T1 (ru)
UA (1) UA123852C2 (ru)
WO (1) WO2019171236A1 (ru)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202020101861U1 (de) * 2020-04-06 2020-04-16 artgerecht GmbH Eisen-enthaltende Formulierung, ernährungsphysiologische Zusammensetzung, welche diese enthält, und Verwendung derselben
IT202000012373A1 (it) * 2020-05-26 2021-11-26 Prosol S P A Formulazione farmaceutica o di integratore alimentare per l’uso nel trattamento di disturbi dovuti alla carenza di ferro
IT202000022003A1 (it) * 2020-09-18 2022-03-18 Difass Int S R L Composizioni comprendenti un sale minerale per uso orale
WO2022118274A1 (en) * 2020-12-03 2022-06-09 Neilos S.r.l. Compositions for the use in the treatment and/or prevention of iron deficiency conditions or diseases
WO2023099493A1 (en) * 2021-12-03 2023-06-08 Dsm Ip Assets B.V. New delivery system for vitamin c
CN117180211A (zh) * 2022-01-13 2023-12-08 上海医药集团青岛国风药业股份有限公司 一种多糖铁复合物的粉末直压片剂
WO2024097926A1 (en) * 2022-11-03 2024-05-10 Nutrition & Biosciences Usa 1, Llc Oral biologic macromolecule delivery system
CN116530687A (zh) * 2023-06-03 2023-08-04 重庆医科大学 一种含乳酸亚铁口服溶液及其用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020022052A1 (en) 2000-04-06 2002-02-21 Dransfield Charles William Transdermal delivery system
CN1218647C (zh) * 2003-04-03 2005-09-14 石家庄三鹿集团股份有限公司 新生婴儿奶粉
WO2007022537A2 (en) 2005-08-19 2007-02-22 Agennix Incorporated Use of lactoferrin as a chemokine and a chemotactic modulator
WO2011019641A2 (en) 2009-08-13 2011-02-17 Nestec S.A. Nutritional compositions including exogenous nucleotides
CA2962136A1 (en) * 2014-11-07 2016-05-12 Mjn U.S. Holdings Llc Nutritional compositions containing a prebiotic and lactoferrin and uses thereof
CA3030022A1 (en) 2016-07-06 2018-01-11 Building Block Nutritionals, Llc Nutritional formula
CN106578134A (zh) * 2016-12-31 2017-04-26 东北农业大学 一种预防感染性腹泻的婴儿配方奶粉
CN107549612B (zh) * 2017-09-12 2021-01-12 东北农业大学 一种提高6-12个月龄婴儿免疫力的营养配方米粉

Also Published As

Publication number Publication date
MA52154B1 (fr) 2022-09-30
HRP20221105T1 (hr) 2022-11-25
UA123852C2 (uk) 2021-06-09
CA3073184C (en) 2021-11-16
BR112020018319A2 (pt) 2020-12-29
SI3661373T1 (sl) 2022-10-28
US12016906B2 (en) 2024-06-25
CO2020010193A2 (es) 2020-08-31
PL3661373T3 (pl) 2022-10-03
RS63563B1 (sr) 2022-10-31
WO2019171236A1 (en) 2019-09-12
PE20201278A1 (es) 2020-11-24
US20200405822A1 (en) 2020-12-31
DK3661373T3 (da) 2022-09-12
EP3661373B1 (en) 2022-06-22
EP3661373A1 (en) 2020-06-10
ES2927216T3 (es) 2022-11-03
AU2019232621A1 (en) 2020-03-12
PH12019550263A1 (en) 2021-01-11
PT3661373T (pt) 2022-09-22
AU2019232621B2 (en) 2020-10-08
SG11202008732VA (en) 2020-10-29
MY183462A (en) 2021-02-18
CA3073184A1 (en) 2019-09-12
LT3661373T (lt) 2022-09-26
HUE059584T2 (hu) 2022-11-28
MA52154A (fr) 2020-06-10
MD3661373T2 (ro) 2022-11-30

Similar Documents

Publication Publication Date Title
EA202090276A1 (ru) Фармацевтическая композиция для лечения анемии
EA201892395A1 (ru) Лекарственные составы ингибитора lsd1
SA519402217B1 (ar) مثبطات إيميدازو بيرازين لكيناز تيروسين بروتون
MX2021004431A (es) Procesos novedosos.
PH12018502634A1 (en) Topical compositions of apremilast
MX2019007587A (es) Composicion oftalmica para el tratamiento de la enfermedad del ojo seco.
MX2020001513A (es) Agentes de union a clec9a y su uso.
EA201992607A1 (ru) Твердые формы берберина урсодезоксихолата, их композиции и способы
MX2019012884A (es) Terapia de combinacion.
EA202191239A1 (ru) Соединения и их применение для лечения дефицита 1-антитрипсина
EA201692481A1 (ru) Комбинация, содержащая глюкокортикоид и edo-s101
BR112018070536A2 (pt) composto, composição farmacêutica, combinação, uso de um composto ou um sal farmaceuticamente aceitável do mesmo, e, método de tratamento de uma doença ou condição
MX2019001850A (es) Formulaciones para administracion oral de principios activos.
MX2021015770A (es) Inhibidores macrociclicos de mcl-1.
BR112018070514A2 (pt) composto, composição farmacêutica, combinação, uso de um composto ou um sal farmaceuticamente aceitável do mesmo, e, método de tratamento de uma doença ou condição
EA201792264A1 (ru) Способы лечения воспалительных заболеваний
EA201991490A1 (ru) Ароматические амиды карбоновых кислот в качестве антагонистов рецепторов брадикинина в1
CR20210499A (es) Compuestos y composiciones como moduladores de la señalización de tlr
EA201892842A1 (ru) Фармацевтические композиции, включающие сафинамид
PH12019501820A1 (en) Pharmaceutical compositions for combination therapy
MX2018003890A (es) Composiciones farmaceuticas que contienen un relajante muscular y un antiinflamatorio no esteroideo (aine).
MX2018006631A (es) Compuesto para uso en la prevencion y tratamiento de enfermedades neurodegenerativas.
EA202090416A1 (ru) Способы лечения симптомов гастропареза с использованием велусетрага
EA201992829A1 (ru) Карбоксильные производные в качестве ингибиторов протеинкиназ
EA202090666A1 (ru) Применение содержащей бензоат композиции для лечения глициновой энцефалопатии