EA201990438A1 - Композиции, содержащие 5-холестен-3,25-диол, 3-сульфат (25hc3s) или его фармацевтически приемлемую соль и по меньшей мере один циклический олигосахарид, и способы их применения - Google Patents

Композиции, содержащие 5-холестен-3,25-диол, 3-сульфат (25hc3s) или его фармацевтически приемлемую соль и по меньшей мере один циклический олигосахарид, и способы их применения

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Publication number
EA201990438A1
EA201990438A1 EA201990438A EA201990438A EA201990438A1 EA 201990438 A1 EA201990438 A1 EA 201990438A1 EA 201990438 A EA201990438 A EA 201990438A EA 201990438 A EA201990438 A EA 201990438A EA 201990438 A1 EA201990438 A1 EA 201990438A1
Authority
EA
Eurasian Patent Office
Prior art keywords
25hc3s
cholesten
diol
acceptable salt
cyclic
Prior art date
Application number
EA201990438A
Other languages
English (en)
Russian (ru)
Inventor
Шуньлинь Жэнь
Лэюань Сюй
Янься Нин
Цзинь Коунг Ким
ВэйЦи Линь
Мее Дзеан Ким
Эндрю Р. Микшталь
Хунвэй У
Минь Л. Ли
Вилма Тамраз
Original Assignee
Вирджиния Коммонвелт Юниверсити
Дьюрект Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Вирджиния Коммонвелт Юниверсити, Дьюрект Корпорейшн filed Critical Вирджиния Коммонвелт Юниверсити
Publication of EA201990438A1 publication Critical patent/EA201990438A1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/738—Cyclodextrins
    • A—HUMAN NECESSITIES
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    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
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EA201990438A 2016-08-02 2017-08-01 Композиции, содержащие 5-холестен-3,25-диол, 3-сульфат (25hc3s) или его фармацевтически приемлемую соль и по меньшей мере один циклический олигосахарид, и способы их применения EA201990438A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662370024P 2016-08-02 2016-08-02
US201762470578P 2017-03-13 2017-03-13
PCT/US2017/044840 WO2018026781A1 (en) 2016-08-02 2017-08-01 Compositions comprising 5-cholesten-3, 25-diol, 3-sulfate (25hc3s) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide

Publications (1)

Publication Number Publication Date
EA201990438A1 true EA201990438A1 (ru) 2019-08-30

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EA201990438A EA201990438A1 (ru) 2016-08-02 2017-08-01 Композиции, содержащие 5-холестен-3,25-диол, 3-сульфат (25hc3s) или его фармацевтически приемлемую соль и по меньшей мере один циклический олигосахарид, и способы их применения

Country Status (22)

Country Link
US (4) US20190269695A1 (enExample)
EP (2) EP4101861A1 (enExample)
JP (3) JP2019524772A (enExample)
KR (3) KR102465046B1 (enExample)
CN (2) CN109983025B (enExample)
AU (2) AU2017305239C1 (enExample)
CA (1) CA3031224A1 (enExample)
DK (1) DK3494125T3 (enExample)
EA (1) EA201990438A1 (enExample)
ES (1) ES2922933T3 (enExample)
HR (1) HRP20220932T1 (enExample)
HU (1) HUE059768T2 (enExample)
IL (2) IL298681A (enExample)
LT (1) LT3494125T (enExample)
MX (2) MX2019001323A (enExample)
PL (1) PL3494125T3 (enExample)
PT (1) PT3494125T (enExample)
RS (1) RS63529B1 (enExample)
SI (1) SI3494125T1 (enExample)
SM (1) SMT202200330T1 (enExample)
TW (2) TW202426000A (enExample)
WO (1) WO2018026781A1 (enExample)

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JP2022549621A (ja) * 2019-09-30 2022-11-28 デュレクト コーポレーション アルコール性肝炎の処置
WO2021163199A1 (en) * 2020-02-11 2021-08-19 Durect Corporation Treatment of infectious diseases
WO2021202608A1 (en) * 2020-03-31 2021-10-07 The Regents Of The University Of Michigan Serum metabolites as biomarkers for carnitine treatment of sepsis
CN115916181A (zh) * 2020-05-22 2023-04-04 度勒科特公司 非酒精性脂肪性肝炎(nash)的治疗
EP4171502A4 (en) * 2020-06-26 2025-02-19 Durect Corporation Use of oxygenated cholesterol sulfates for treating inflammatory conditions
CN112967234B (zh) * 2021-02-09 2022-12-09 复旦大学附属中山医院 冠状动脉功能生理学病变模式定量评价方法
WO2022272103A1 (en) * 2021-06-25 2022-12-29 Durect Corporation 25-hydroxy-cholest-5-en-3-sulfate choline and methods for preparing, and uses of, same
CN113750039B (zh) * 2021-10-26 2023-08-18 浙江中医药大学 一种黄芩苷-海藻酸钙温敏纳米凝胶、制备方法及其应用
WO2023196412A1 (en) * 2022-04-06 2023-10-12 Nobias Therapeutics, Inc. Liquid formulations comprising mitogen-activated protein kinase kinase (mek) inhibitors and methods using same
CN119896674A (zh) * 2023-10-27 2025-04-29 上海交通大学医学院附属新华医院 胆固醇硫酸酯在制备治疗特应性皮炎的药物中的应用

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