EA201892191A1 - Соединения гетероарил-1,2,4-триазола и гетероарил-тетразола для контроля над эктопаразитами - Google Patents
Соединения гетероарил-1,2,4-триазола и гетероарил-тетразола для контроля над эктопаразитамиInfo
- Publication number
- EA201892191A1 EA201892191A1 EA201892191A EA201892191A EA201892191A1 EA 201892191 A1 EA201892191 A1 EA 201892191A1 EA 201892191 A EA201892191 A EA 201892191A EA 201892191 A EA201892191 A EA 201892191A EA 201892191 A1 EA201892191 A1 EA 201892191A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- heteroaryl
- alkyl
- optionally substituted
- pyridazine
- pyrazine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pyridine Compounds (AREA)
Abstract
В данном изобретении предлагаются соединения формулыгде X представляет собой O или S; Qи Qнезависимо представляют собой CRили N при условии, что по меньшей мере один из Qи Qпредставляет собой N; Y представляет собой прямую связь или CH; Rпредставляет собой H; C-C-алкил, необязательно замещенный одним заместителем, выбранным из CN, CONH, COOH, NOи -Si(CH); C-C-галогеналкила; C-C-алкенила; C-C-галогеналкенила; C-C-алкинила; C-C-галогеналкинила; C-C-циклоалкил-C-C-алкила, где C-C-циклоалкил необязательно замещен 1 или 2 атомами галогена; оксетан-3-ил-CH-; или бензил, необязательно замещенный галогеном или C-C-галогеналкилом; Rпредставляет собой фенил, пиридин, пиримидин, пиразин или пиридазин, где фенил, пиридин, пиримидин, пиразин или пиридазин необязательно замещен одним-тремя заместителями, при условии, что заместитель (заместители) не находятся на углероде, соседнем с углеродом, связанным с- группой, каждая из которых независимо выбрана из C-C-алкила, C-C-галогеналкила, C-C-тиоалкила, C-C-алкокси, C-C-галогеналкокси, галогена, NO, SF, CN, CONH, COOH и C(S)NH; Rпредставляет собой C-C-алкил или C-C-галогеналкил; Rпредставляет собой пиридин, пиримидин, пиразин или пиридазин, где пиридин, пиримидин, пиразин или пиридазин необязательно замещен одним заместителем, выбранным из C-C-алкила, C-C-галогеналкила, C-C-алкокси, C-C-циклоалкила, галогена или гидрокси.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662332004P | 2016-05-05 | 2016-05-05 | |
| PCT/US2017/030082 WO2017192385A1 (en) | 2016-05-05 | 2017-04-28 | Heteroaryl-1,2,4-triazole and heteroaryl-tetrazole compounds for controlling ectoparasites |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201892191A1 true EA201892191A1 (ru) | 2019-04-30 |
| EA036478B1 EA036478B1 (ru) | 2020-11-16 |
Family
ID=58672822
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201892191A EA036478B1 (ru) | 2016-05-05 | 2017-04-28 | Соединения гетероарил-1,2,4-триазола и гетероарилтетразола и их применение для контроля над эктопаразитами |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US10287276B2 (ru) |
| EP (1) | EP3452460B1 (ru) |
| JP (1) | JP6370504B2 (ru) |
| KR (1) | KR102174828B1 (ru) |
| CN (1) | CN109311841B (ru) |
| AR (1) | AR108222A1 (ru) |
| AU (1) | AU2017261187B2 (ru) |
| BR (1) | BR112018069578B1 (ru) |
| CA (1) | CA3023208C (ru) |
| CL (1) | CL2018003021A1 (ru) |
| CO (1) | CO2018011825A2 (ru) |
| DK (1) | DK3452460T3 (ru) |
| EA (1) | EA036478B1 (ru) |
| ES (1) | ES2776850T3 (ru) |
| MX (1) | MX2018012951A (ru) |
| NZ (1) | NZ746361A (ru) |
| PL (1) | PL3452460T3 (ru) |
| PT (1) | PT3452460T (ru) |
| TW (2) | TWI696615B (ru) |
| WO (1) | WO2017192385A1 (ru) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20200404919A1 (en) | 2018-03-08 | 2020-12-31 | Bayer Aktiengesellschaft | Use of heteroaryl-triazole and heteroaryl-tetrazole compounds as pesticides in plant protection |
| CN116969925A (zh) * | 2018-04-12 | 2023-10-31 | 拜耳公司 | 杂芳基-三唑化合物 |
| UY38184A (es) * | 2018-04-17 | 2019-10-31 | Bayer Ag | Compuestos heteroarilo-triazol y heteroarilo-tetrazol novedosos como plaguicidas |
| JP2021522181A (ja) | 2018-04-20 | 2021-08-30 | バイエル・アクチエンゲゼルシヤフト | 殺有害生物剤としてのヘテロアリール−トリアゾール化合物及びヘテロアリール−テトラゾール化合物 |
| FI3784661T3 (fi) * | 2018-04-25 | 2024-02-14 | Bayer Ag | Uusia heteroaryylitriatsoli- ja heteroaryylitetratsoliyhdisteitä tuholaismyrkkyinä |
| BR112020022659A2 (pt) * | 2018-05-08 | 2021-02-02 | Syngenta Crop Protection Ag | métodos de aplicação de um ou mais determinados compostos de heteroaril-1,2,4-triazol e heteroaril-tetrazol para o controle de danos em plantas, seu material de propagação e produtos derivados de plantas |
| JOP20200340A1 (ar) | 2018-06-29 | 2020-12-27 | Syngenta Participations Ag | مركبات آزول-أميد النشطة من الناحية المبيدة للآفات |
| UY38367A (es) * | 2018-09-13 | 2020-04-30 | Syngenta Participations Ag | Compuestos de azol-amida pesticidamente activos |
| UY38366A (es) | 2018-09-13 | 2020-04-30 | Syngenta Participations Ag | Compuestos de azol-amida pesticidamente activos |
| EP3860987B1 (en) * | 2018-10-02 | 2023-07-19 | Syngenta Participations Ag | Pesticidally active benzene- and azine-amide compounds |
| EP3867237B1 (en) | 2018-10-19 | 2023-06-07 | Syngenta Participations Ag | Pesticidally active azole-amide compounds |
| WO2020094363A1 (en) | 2018-11-05 | 2020-05-14 | Syngenta Participations Ag | Pesticidally active azole-amide compounds |
| EP3696175A1 (en) | 2019-02-18 | 2020-08-19 | Syngenta Crop Protection AG | Pesticidally active azole-amide compounds |
| JP2022523434A (ja) | 2019-03-08 | 2022-04-22 | シンジェンタ クロップ プロテクション アクチェンゲゼルシャフト | 殺有害生物的に活性なアゾール－アミド化合物 |
| EP3941912B1 (en) | 2019-03-20 | 2023-12-13 | Syngenta Crop Protection AG | Pesticidally active azole amide compounds |
| EP3941915A1 (en) | 2019-03-20 | 2022-01-26 | Syngenta Crop Protection AG | Pesticidally active azole amide compounds |
| WO2020193341A1 (en) | 2019-03-22 | 2020-10-01 | Syngenta Crop Protection Ag | N-[1-(5-bromo-2-pyrimidin-2-yl-1,2,4-triazol-3-yl)ethyl]-2-cyclopropyl-6-(trifluoromethyl)pyridine-4-carboxamide derivatives and related compounds as insecticides |
| UY38623A (es) | 2019-03-29 | 2020-10-30 | Syngenta Crop Protection Ag | Compuestos de diazina-amida activos como pesticidas |
| KR20210149113A (ko) * | 2019-04-05 | 2021-12-08 | 신젠타 크롭 프로텍션 아게 | 살충 활성 디아진-아미드 화합물 |
| JOP20210273A1 (ar) | 2019-04-11 | 2023-01-30 | Syngenta Crop Protection Ag | مركبات دايازين - أميد نشطة بشكل مبيد للآفات |
| EP3725788A1 (en) | 2019-04-15 | 2020-10-21 | Bayer AG | Novel heteroaryl-substituted aminoalkyl azole compounds as pesticides |
| AU2020318590A1 (en) | 2019-07-23 | 2022-02-17 | Bayer Aktiengesellschaft | Novel heteroaryl-triazole compounds as pesticides |
| KR20220038402A (ko) | 2019-07-23 | 2022-03-28 | 바이엘 악티엔게젤샤프트 | 살충제로서의 신규 헤테로아릴-트리아졸 화합물 |
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| JP2023007504A (ja) * | 2019-09-30 | 2023-01-19 | 日本農薬株式会社 | イミン化合物またはその塩、および該化合物を有効成分として含有する有害生物防除剤並びに有害生物防除方法 |
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| WO2021069567A1 (en) | 2019-10-09 | 2021-04-15 | Bayer Aktiengesellschaft | Novel heteroaryl-triazole compounds as pesticides |
| WO2021068179A1 (en) * | 2019-10-11 | 2021-04-15 | Bayer Animal Health Gmbh | Novel heteroaryl-substituted pyrazine derivatives as pesticides |
| TW202128650A (zh) * | 2019-10-11 | 2021-08-01 | 德商拜耳動物保健有限公司 | 作為殺蟲劑之新穎的雜芳基取代之吡𠯤衍生物 |
| CN114630825A (zh) | 2019-11-01 | 2022-06-14 | 先正达农作物保护股份公司 | 杀有害生物活性的稠合二环杂芳香族化合物 |
| TW202134226A (zh) | 2019-11-18 | 2021-09-16 | 德商拜耳廠股份有限公司 | 作為殺蟲劑之新穎雜芳基-三唑化合物 |
| TW202136248A (zh) | 2019-11-25 | 2021-10-01 | 德商拜耳廠股份有限公司 | 作為殺蟲劑之新穎雜芳基-三唑化合物 |
| MX2022007671A (es) | 2019-12-18 | 2022-07-19 | Intervet Int Bv | Compuestos antihelminticos que comprenden una estructura de azaindoles. |
| US20230148316A1 (en) | 2019-12-18 | 2023-05-11 | Intervet Inc. | Anthelmintic compounds comprising a quinoline structure |
| WO2021122645A1 (en) | 2019-12-20 | 2021-06-24 | Syngenta Crop Protection Ag | Pesticidally active azole-amide compounds |
| JP2023513624A (ja) | 2020-02-18 | 2023-03-31 | バイエル・アクチエンゲゼルシヤフト | 殺有害生物剤としてのヘテロアリール－トリアゾール化合物 |
| WO2021170881A1 (en) | 2020-02-27 | 2021-09-02 | Syngenta Crop Protection Ag | Pesticidally active diazine-bisamide compounds |
| TW202208347A (zh) | 2020-05-06 | 2022-03-01 | 德商拜耳廠股份有限公司 | 作為殺蟲劑之新穎雜芳基三唑化合物 |
| EP3909950A1 (en) | 2020-05-13 | 2021-11-17 | Basf Se | Heterocyclic compounds for the control of invertebrate pests |
| CN115551848A (zh) | 2020-05-13 | 2022-12-30 | 巴斯夫欧洲公司 | 用于防治无脊椎动物害虫的杂环化合物 |
| EP3929189A1 (en) | 2020-06-25 | 2021-12-29 | Bayer Animal Health GmbH | Novel heteroaryl-substituted pyrazine derivatives as pesticides |
| WO2022101265A1 (en) | 2020-11-13 | 2022-05-19 | Syngenta Crop Protection Ag | Pesticidally active fused bicyclic heteroaromatic compounds |
| US20240043446A1 (en) | 2020-12-11 | 2024-02-08 | Intervet Inc. | Anthelmintic compounds comprising a thienopyridine structure |
| JP2024516278A (ja) | 2021-05-06 | 2024-04-12 | バイエル・アクチエンゲゼルシヤフト | アルキルアミド置換環付加イミダゾール類及び殺虫剤としてのそれらの使用 |
| EP4119547A1 (en) | 2021-07-12 | 2023-01-18 | Basf Se | Triazole compounds for the control of invertebrate pests |
| WO2023285175A1 (en) | 2021-07-12 | 2023-01-19 | Basf Se | Triazole compounds for the control of invertebrate pests |
| EP4377312A1 (en) | 2021-07-29 | 2024-06-05 | Syngenta Crop Protection AG | Pesticidally active fused bicyclic heteroaromatic compounds |
| EP4140986A1 (en) | 2021-08-23 | 2023-03-01 | Basf Se | Pyrazine compounds for the control of invertebrate pests |
| WO2023025602A1 (en) | 2021-08-23 | 2023-03-02 | Basf Se | Pyrazine compounds for the control of invertebrate pests |
| AU2022335669A1 (en) | 2021-08-25 | 2024-02-01 | Bayer Aktiengesellschaft | Novel pyrazinyl-triazole compounds as pesticides |
| EP4140995A1 (en) | 2021-08-27 | 2023-03-01 | Basf Se | Pyrazine compounds for the control of invertebrate pests |
| WO2023025617A1 (en) | 2021-08-27 | 2023-03-02 | Basf Se | Pyrazine compounds for the control of invertebrate pests |
| TW202328089A (zh) | 2021-09-08 | 2023-07-16 | 印度商皮埃企業有限公司 | 包含芳香羧醯胺的亞磺醯亞胺／磺醯亞胺（ｓｕｌｆｏｘｉｍｉｎｅｓ／ｓｕｌｆｉｌｉｍｉｎｅ）化合物及其用途 |
| WO2023041422A1 (en) | 2021-09-20 | 2023-03-23 | Basf Se | Heterocyclic compounds for the control of invertebrate pests |
| EP4151631A1 (en) | 2021-09-20 | 2023-03-22 | Basf Se | Heterocyclic compounds for the control of invertebrate pests |
| CN118076598A (zh) | 2021-10-08 | 2024-05-24 | 日本农药株式会社 | 嘧啶基三唑化合物或其盐及含有该化合物作为有效成分的害虫防除剂以及害虫防除方法 |
| EP4198033A1 (en) | 2021-12-14 | 2023-06-21 | Basf Se | Heterocyclic compounds for the control of invertebrate pests |
| TW202341864A (zh) | 2022-04-14 | 2023-11-01 | 美商富曼西公司 | 用於防治無脊椎有害生物之新型磺酸酯苯甲醯胺化合物 |
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2017
- 2017-04-18 TW TW108101343A patent/TWI696615B/zh active
- 2017-04-18 AR ARP170100984A patent/AR108222A1/es unknown
- 2017-04-18 TW TW106112893A patent/TWI679197B/zh active
- 2017-04-28 WO PCT/US2017/030082 patent/WO2017192385A1/en active Application Filing
- 2017-04-28 EA EA201892191A patent/EA036478B1/ru not_active IP Right Cessation
- 2017-04-28 CA CA3023208A patent/CA3023208C/en active Active
- 2017-04-28 AU AU2017261187A patent/AU2017261187B2/en active Active
- 2017-04-28 US US15/556,722 patent/US10287276B2/en active Active
- 2017-04-28 PT PT177223534T patent/PT3452460T/pt unknown
- 2017-04-28 NZ NZ746361A patent/NZ746361A/en unknown
- 2017-04-28 ES ES17722353T patent/ES2776850T3/es active Active
- 2017-04-28 MX MX2018012951A patent/MX2018012951A/es active IP Right Grant
- 2017-04-28 KR KR1020187031569A patent/KR102174828B1/ko active IP Right Grant
- 2017-04-28 DK DK17722353.4T patent/DK3452460T3/da active
- 2017-04-28 JP JP2017563601A patent/JP6370504B2/ja active Active
- 2017-04-28 PL PL17722353T patent/PL3452460T3/pl unknown
- 2017-04-28 EP EP17722353.4A patent/EP3452460B1/en active Active
- 2017-04-28 CN CN201780027598.5A patent/CN109311841B/zh active Active
- 2017-04-28 BR BR112018069578-5A patent/BR112018069578B1/pt active IP Right Grant
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2018
- 2018-10-24 CL CL2018003021A patent/CL2018003021A1/es unknown
- 2018-10-31 CO CONC2018/0011825A patent/CO2018011825A2/es unknown
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2019
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| ES2776850T3 (es) | 2020-08-03 |
| CO2018011825A2 (es) | 2018-11-22 |
| DK3452460T3 (da) | 2020-03-16 |
| JP6370504B2 (ja) | 2018-08-08 |
| PT3452460T (pt) | 2020-03-24 |
| EP3452460A1 (en) | 2019-03-13 |
| AU2017261187A1 (en) | 2018-10-04 |
| CN109311841B (zh) | 2021-04-27 |
| NZ746361A (en) | 2020-04-24 |
| US20180186778A1 (en) | 2018-07-05 |
| BR112018069578A2 (pt) | 2019-01-22 |
| US10981897B2 (en) | 2021-04-20 |
| MX2018012951A (es) | 2019-01-21 |
| EA036478B1 (ru) | 2020-11-16 |
| CA3023208A1 (en) | 2017-11-09 |
| WO2017192385A1 (en) | 2017-11-09 |
| JP2018517716A (ja) | 2018-07-05 |
| BR112018069578B1 (pt) | 2024-02-06 |
| AU2017261187B2 (en) | 2019-04-18 |
| TWI679197B (zh) | 2019-12-11 |
| PL3452460T3 (pl) | 2020-06-01 |
| AR108222A1 (es) | 2018-08-01 |
| TW201938548A (zh) | 2019-10-01 |
| CA3023208C (en) | 2020-11-03 |
| CL2018003021A1 (es) | 2019-02-15 |
| TW201803863A (zh) | 2018-02-01 |
| TWI696615B (zh) | 2020-06-21 |
| US10287276B2 (en) | 2019-05-14 |
| KR20180132100A (ko) | 2018-12-11 |
| US20190256501A1 (en) | 2019-08-22 |
| EP3452460B1 (en) | 2020-02-12 |
| KR102174828B1 (ko) | 2020-11-06 |
| CN109311841A (zh) | 2019-02-05 |
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