CO2018011825A2 - Compuestos heteroaril-1,2,4-triazol y heteroaril-tetrazol - Google Patents
Compuestos heteroaril-1,2,4-triazol y heteroaril-tetrazolInfo
- Publication number
- CO2018011825A2 CO2018011825A2 CONC2018/0011825A CO2018011825A CO2018011825A2 CO 2018011825 A2 CO2018011825 A2 CO 2018011825A2 CO 2018011825 A CO2018011825 A CO 2018011825A CO 2018011825 A2 CO2018011825 A2 CO 2018011825A2
- Authority
- CO
- Colombia
- Prior art keywords
- haloalkyl
- alkyl
- alkoxy
- optionally substituted
- heteroaryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pyridine Compounds (AREA)
Abstract
La presente invención proporciona compuestos de fórmula: en donde: X es O o S; Q1 y Q2 son independientemente CR5 o N, siempre que al menos uno de Q1 y Q2 sea N; Y es un enlace directo o CH2; R1 es H; alquilo C1-C6 opcionalmente sustituido con un sustituyente seleccionado de: CN, CONH2, COOH, NO2 y -Si(CH3)3; haloalquilo C1-C6; alquenilo C2-C6; haloalquenilo C2-C6; alquinilo C2-C6; haloalquinilo C2-C6; cicloalquil C3-C4-alquilo C1-C2 en donde cicloalquilo C3-C4 está opcionalmente sustituido con 1 o 2 átomos halo; oxetan-3-il-CH2; o bencilo opcionalmente sustituido con halo o haloalquilo C1-C3; R2 es fenilo, piridina, pirimidina, pirazina o piridazina, en donde el fenilo, piridina, pirimidina, pirazina o piridazina está opcionalmente sustituido con uno a tres sustituyentes, siempre que el o los sustituyentes no estén en carbono adyacente al carbono unido al grupo , cada uno independientemente seleccionado de: alquilo C1-C3, haloalquilo C1-C3, tiohaloalquilo C1-C3, alcoxi C1-C3, haloalcoxi C1-C3, halo, NO2, SF5, CN, CONH2, COOH y C(S)NH2; R3 es alquilo C1-C3 o haloalquilo C1-C3; R4 es piridina, pirimidina, pirazina o piridazina, en donde la piridina, pirimidina, pirazina o piridazina está opcionalmente sustituida con un sustituyente seleccionado de: alquilo C1-C3, haloalquilo C1-C3, alcoxi C1-C3, cicloalquilo C3-C4, halo o hidroxi; R5 es H, alquilo C1-C3, haloalquilo C1-C3, cicloalquilo C3-C4, alcoxi C1-C3, alcoxi C1-C3C(O)- o (alcoxi C1-C3)2CH-; o una sal del mismo.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662332004P | 2016-05-05 | 2016-05-05 | |
| PCT/US2017/030082 WO2017192385A1 (en) | 2016-05-05 | 2017-04-28 | Heteroaryl-1,2,4-triazole and heteroaryl-tetrazole compounds for controlling ectoparasites |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO2018011825A2 true CO2018011825A2 (es) | 2018-11-22 |
Family
ID=58672822
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CONC2018/0011825A CO2018011825A2 (es) | 2016-05-05 | 2018-10-31 | Compuestos heteroaril-1,2,4-triazol y heteroaril-tetrazol |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US10287276B2 (es) |
| EP (1) | EP3452460B1 (es) |
| JP (1) | JP6370504B2 (es) |
| KR (1) | KR102174828B1 (es) |
| CN (1) | CN109311841B (es) |
| AR (1) | AR108222A1 (es) |
| AU (1) | AU2017261187B2 (es) |
| BR (1) | BR112018069578B1 (es) |
| CA (1) | CA3023208C (es) |
| CL (1) | CL2018003021A1 (es) |
| CO (1) | CO2018011825A2 (es) |
| DK (1) | DK3452460T3 (es) |
| EA (1) | EA036478B1 (es) |
| ES (1) | ES2776850T3 (es) |
| MX (1) | MX2018012951A (es) |
| NZ (1) | NZ746361A (es) |
| PL (1) | PL3452460T3 (es) |
| PT (1) | PT3452460T (es) |
| TW (2) | TWI696615B (es) |
| WO (1) | WO2017192385A1 (es) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2021516238A (ja) | 2018-03-08 | 2021-07-01 | バイエル・アクチエンゲゼルシヤフト | 植物保護における殺有害生物剤としてのヘテロアリール−トリアゾール化合物及びヘテロアリール−テトラゾール化合物の使用 |
| AU2019250361B2 (en) * | 2018-04-12 | 2023-03-23 | Bayer Aktiengesellschaft | Heteroaryl-triazole compounds as pesticides |
| UY38184A (es) * | 2018-04-17 | 2019-10-31 | Bayer Ag | Compuestos heteroarilo-triazol y heteroarilo-tetrazol novedosos como plaguicidas |
| WO2019202077A1 (en) * | 2018-04-20 | 2019-10-24 | Bayer Aktiengesellschaft | Heteroaryl-triazole and heteroaryl-tetrazole compounds as pesticides |
| MX2020011275A (es) | 2018-04-25 | 2020-11-13 | Bayer Ag | Novedosos compuestos de heteroaril-triazol y hetroaril[-]tetrazol como plaguicidas. |
| US20210068395A1 (en) | 2018-05-08 | 2021-03-11 | Syngenta Crop Protection Ag | Methods of applying one or more certain heteroaryl-1,2,4-triazole and heteroaryl-tetrazole compounds to control damage on plants, propagation material thereof, and plant derived products |
| US20210267203A1 (en) * | 2018-06-29 | 2021-09-02 | Syngenta Participations Ag | Pesticidally active azole-amide compounds |
| UY38366A (es) | 2018-09-13 | 2020-04-30 | Syngenta Participations Ag | Compuestos de azol-amida pesticidamente activos |
| TW202023386A (zh) | 2018-09-13 | 2020-07-01 | 瑞士商先正達合夥公司 | 殺有害生物活性唑-醯胺化合物 |
| CN112839933A (zh) * | 2018-10-02 | 2021-05-25 | 先正达参股股份有限公司 | 杀有害生物活性苯-酰胺和吖嗪-酰胺化合物 |
| TW202033512A (zh) | 2018-10-19 | 2020-09-16 | 瑞士商先正達農作物保護公司 | 殺有害生物活性唑-醯胺化合物 |
| CN112955442A (zh) * | 2018-11-05 | 2021-06-11 | 先正达参股股份有限公司 | 杀有害生物活性的唑-酰胺化合物 |
| EP3696175A1 (en) | 2019-02-18 | 2020-08-19 | Syngenta Crop Protection AG | Pesticidally active azole-amide compounds |
| US20220167618A1 (en) | 2019-03-08 | 2022-06-02 | Syngenta Crop Protection Ag | Pesticidally active azole-amide compounds |
| BR112021018495A2 (pt) | 2019-03-20 | 2021-11-30 | Syngenta Crop Protection Ag | Compostos de azolamida ativos em termos pesticidas |
| US20220183294A1 (en) | 2019-03-20 | 2022-06-16 | Syngenta Crop Protection Ag | Pesticidally active azole amide compounds |
| CN113597426A (zh) * | 2019-03-22 | 2021-11-02 | 先正达农作物保护股份公司 | N-[1-(5-溴-2-嘧啶-2-基-1,2,4-三唑-3-基)乙基]-2-环丙基-6-(三氟甲基)吡啶-4-甲酰胺衍生物及相关的化合物作为杀昆虫剂 |
| TW202102489A (zh) | 2019-03-29 | 2021-01-16 | 瑞士商先正達農作物保護公司 | 殺有害生物活性之二𠯤-醯胺化合物 |
| JP2022527548A (ja) * | 2019-04-05 | 2022-06-02 | シンジェンタ クロップ プロテクション アクチェンゲゼルシャフト | 殺有害生物的に活性なジアジン－アミド化合物 |
| EP3953343A1 (en) | 2019-04-11 | 2022-02-16 | Syngenta Crop Protection AG | Pesticidally active diazine-amide compounds |
| EP3725788A1 (en) | 2019-04-15 | 2020-10-21 | Bayer AG | Novel heteroaryl-substituted aminoalkyl azole compounds as pesticides |
| BR112022000915A2 (pt) * | 2019-07-23 | 2022-05-17 | Bayer Ag | Compostos de heteroaril-triazol como pesticidas |
| CA3148209A1 (en) * | 2019-07-23 | 2021-01-28 | Bayer Aktiengesellschaft | Novel heteroaryl-triazole compounds as pesticides |
| US20220289715A1 (en) | 2019-08-23 | 2022-09-15 | Syngenta Crop Protection Ag | Pesticidally active pyrazine-amide compounds |
| JP2023007504A (ja) * | 2019-09-30 | 2023-01-19 | 日本農薬株式会社 | イミン化合物またはその塩、および該化合物を有効成分として含有する有害生物防除剤並びに有害生物防除方法 |
| EP4041721B1 (en) * | 2019-10-09 | 2024-03-06 | Bayer Aktiengesellschaft | Novel heteroaryl-triazole compounds as pesticides |
| KR20220081359A (ko) | 2019-10-09 | 2022-06-15 | 바이엘 악티엔게젤샤프트 | 살충제로서의 신규 헤테로아릴-트리아졸 화합물 |
| TW202128650A (zh) | 2019-10-11 | 2021-08-01 | 德商拜耳動物保健有限公司 | 作為殺蟲劑之新穎的雜芳基取代之吡𠯤衍生物 |
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| PE20221765A1 (es) * | 2019-11-01 | 2022-11-11 | Syngenta Crop Protection Ag | Compuestos heteroaromaticos biciclicos condensados activos como pesticidas |
| TW202134226A (zh) | 2019-11-18 | 2021-09-16 | 德商拜耳廠股份有限公司 | 作為殺蟲劑之新穎雜芳基-三唑化合物 |
| TW202136248A (zh) | 2019-11-25 | 2021-10-01 | 德商拜耳廠股份有限公司 | 作為殺蟲劑之新穎雜芳基-三唑化合物 |
| US20230110397A1 (en) | 2019-12-18 | 2023-04-13 | Intervet Inc. | Anthelmintic compounds comprising azaindoles structure |
| EP4077281A1 (en) | 2019-12-18 | 2022-10-26 | Intervet International B.V. | Anthelmintic compounds comprising a quinoline structure |
| WO2021122645A1 (en) | 2019-12-20 | 2021-06-24 | Syngenta Crop Protection Ag | Pesticidally active azole-amide compounds |
| MX2022010059A (es) | 2020-02-18 | 2022-08-25 | Bayer Ag | Nuevos compuestos de heteroaril-triazol como pesticidas. |
| JP2023515979A (ja) | 2020-02-27 | 2023-04-17 | シンジェンタ クロップ プロテクション アクチェンゲゼルシャフト | 殺有害生物的に活性なジアジン－ビスアミド化合物 |
| TW202208347A (zh) | 2020-05-06 | 2022-03-01 | 德商拜耳廠股份有限公司 | 作為殺蟲劑之新穎雜芳基三唑化合物 |
| EP3909950A1 (en) | 2020-05-13 | 2021-11-17 | Basf Se | Heterocyclic compounds for the control of invertebrate pests |
| WO2021228594A1 (en) | 2020-05-13 | 2021-11-18 | Basf Se | Heterocyclic compounds for the control of invertebrate pests |
| EP3929189A1 (en) | 2020-06-25 | 2021-12-29 | Bayer Animal Health GmbH | Novel heteroaryl-substituted pyrazine derivatives as pesticides |
| WO2022101265A1 (en) | 2020-11-13 | 2022-05-19 | Syngenta Crop Protection Ag | Pesticidally active fused bicyclic heteroaromatic compounds |
| JP2023553428A (ja) | 2020-12-11 | 2023-12-21 | インターベット インターナショナル ベー． フェー． | チエノピリジン構造を含む駆虫剤化合物 |
| CN117597344A (zh) | 2021-05-06 | 2024-02-23 | 拜耳公司 | 烷基酰胺取代的环状咪唑及其作为杀虫剂的用途 |
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| WO2023285175A1 (en) | 2021-07-12 | 2023-01-19 | Basf Se | Triazole compounds for the control of invertebrate pests |
| AU2022318251A1 (en) | 2021-07-29 | 2024-01-25 | Syngenta Crop Protection Ag | Pesticidally active fused bicyclic heteroaromatic compounds |
| EP4140986A1 (en) | 2021-08-23 | 2023-03-01 | Basf Se | Pyrazine compounds for the control of invertebrate pests |
| WO2023025602A1 (en) | 2021-08-23 | 2023-03-02 | Basf Se | Pyrazine compounds for the control of invertebrate pests |
| KR20240051198A (ko) | 2021-08-25 | 2024-04-19 | 바이엘 악티엔게젤샤프트 | 농약제로서 신규 피라지닐-트리아졸 화합물 |
| KR20240052751A (ko) | 2021-08-27 | 2024-04-23 | 바스프 에스이 | 무척추 해충의 방제를 위한 피라진 화합물 |
| EP4140995A1 (en) | 2021-08-27 | 2023-03-01 | Basf Se | Pyrazine compounds for the control of invertebrate pests |
| WO2023037249A1 (en) | 2021-09-08 | 2023-03-16 | Pi Industries Ltd. | Sulfoximines/ sulfilimine containing aromatic caboxamide compounds and their use therof |
| EP4151631A1 (en) | 2021-09-20 | 2023-03-22 | Basf Se | Heterocyclic compounds for the control of invertebrate pests |
| WO2023041422A1 (en) | 2021-09-20 | 2023-03-23 | Basf Se | Heterocyclic compounds for the control of invertebrate pests |
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| EP4198033A1 (en) | 2021-12-14 | 2023-06-21 | Basf Se | Heterocyclic compounds for the control of invertebrate pests |
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2017
- 2017-04-18 AR ARP170100984A patent/AR108222A1/es unknown
- 2017-04-18 TW TW108101343A patent/TWI696615B/zh active
- 2017-04-18 TW TW106112893A patent/TWI679197B/zh active
- 2017-04-28 JP JP2017563601A patent/JP6370504B2/ja active Active
- 2017-04-28 CA CA3023208A patent/CA3023208C/en active Active
- 2017-04-28 WO PCT/US2017/030082 patent/WO2017192385A1/en active Application Filing
- 2017-04-28 DK DK17722353.4T patent/DK3452460T3/da active
- 2017-04-28 MX MX2018012951A patent/MX2018012951A/es active IP Right Grant
- 2017-04-28 EA EA201892191A patent/EA036478B1/ru not_active IP Right Cessation
- 2017-04-28 CN CN201780027598.5A patent/CN109311841B/zh active Active
- 2017-04-28 ES ES17722353T patent/ES2776850T3/es active Active
- 2017-04-28 KR KR1020187031569A patent/KR102174828B1/ko active IP Right Grant
- 2017-04-28 PT PT177223534T patent/PT3452460T/pt unknown
- 2017-04-28 US US15/556,722 patent/US10287276B2/en active Active
- 2017-04-28 PL PL17722353T patent/PL3452460T3/pl unknown
- 2017-04-28 NZ NZ746361A patent/NZ746361A/en unknown
- 2017-04-28 EP EP17722353.4A patent/EP3452460B1/en active Active
- 2017-04-28 BR BR112018069578-5A patent/BR112018069578B1/pt active IP Right Grant
- 2017-04-28 AU AU2017261187A patent/AU2017261187B2/en active Active
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2018
- 2018-10-24 CL CL2018003021A patent/CL2018003021A1/es unknown
- 2018-10-31 CO CONC2018/0011825A patent/CO2018011825A2/es unknown
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2019
- 2019-04-30 US US16/399,330 patent/US10981897B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| TWI696615B (zh) | 2020-06-21 |
| TW201938548A (zh) | 2019-10-01 |
| KR20180132100A (ko) | 2018-12-11 |
| EP3452460B1 (en) | 2020-02-12 |
| CN109311841A (zh) | 2019-02-05 |
| EA036478B1 (ru) | 2020-11-16 |
| EA201892191A1 (ru) | 2019-04-30 |
| EP3452460A1 (en) | 2019-03-13 |
| CA3023208C (en) | 2020-11-03 |
| PL3452460T3 (pl) | 2020-06-01 |
| PT3452460T (pt) | 2020-03-24 |
| US20180186778A1 (en) | 2018-07-05 |
| AU2017261187B2 (en) | 2019-04-18 |
| US10287276B2 (en) | 2019-05-14 |
| DK3452460T3 (da) | 2020-03-16 |
| CL2018003021A1 (es) | 2019-02-15 |
| BR112018069578A2 (pt) | 2019-01-22 |
| JP2018517716A (ja) | 2018-07-05 |
| MX2018012951A (es) | 2019-01-21 |
| AU2017261187A1 (en) | 2018-10-04 |
| CN109311841B (zh) | 2021-04-27 |
| NZ746361A (en) | 2020-04-24 |
| US10981897B2 (en) | 2021-04-20 |
| WO2017192385A1 (en) | 2017-11-09 |
| TW201803863A (zh) | 2018-02-01 |
| KR102174828B1 (ko) | 2020-11-06 |
| ES2776850T3 (es) | 2020-08-03 |
| CA3023208A1 (en) | 2017-11-09 |
| US20190256501A1 (en) | 2019-08-22 |
| JP6370504B2 (ja) | 2018-08-08 |
| AR108222A1 (es) | 2018-08-01 |
| TWI679197B (zh) | 2019-12-11 |
| BR112018069578B1 (pt) | 2024-02-06 |
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