EA201890020A1 - Способы и композиции для лечения ассоциированных со старением состояний - Google Patents

Способы и композиции для лечения ассоциированных со старением состояний

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Publication number
EA201890020A1
EA201890020A1 EA201890020A EA201890020A EA201890020A1 EA 201890020 A1 EA201890020 A1 EA 201890020A1 EA 201890020 A EA201890020 A EA 201890020A EA 201890020 A EA201890020 A EA 201890020A EA 201890020 A1 EA201890020 A1 EA 201890020A1
Authority
EA
Eurasian Patent Office
Prior art keywords
methods
aging
compositions
treatment
aging states
Prior art date
Application number
EA201890020A
Other languages
English (en)
Inventor
Антон Висс-Корэй
Джозеф М. Кастельяно
Original Assignee
Зе Боард Оф Трастиз Оф Зе Леланд Стэнфорд Джуниор Юниверсити
Ю. С. Говернмент Эз Репрезентид Бай Зе Департмент Оф Ветеранс Эффэйрс
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Зе Боард Оф Трастиз Оф Зе Леланд Стэнфорд Джуниор Юниверсити, Ю. С. Говернмент Эз Репрезентид Бай Зе Департмент Оф Ветеранс Эффэйрс filed Critical Зе Боард Оф Трастиз Оф Зе Леланд Стэнфорд Джуниор Юниверсити
Publication of EA201890020A1 publication Critical patent/EA201890020A1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Предусмотрены способы лечения ассоциированного со старением состояния у взрослого млекопитающего. Аспекты способов включают в себя усиление активности TIMP, например активности TIMP2, у млекопитающего в достаточной степени для лечения ассоциированного со старением состояния у взрослого млекопитающего. Кроме того, предусмотрены композиции для применения в осуществлении на практике способов согласно настоящему изобретению. Разнообразные ассоциированные со старением состояния можно лечить путем осуществления на практике настоящих способов, причем состояния включают в себя когнитивные нарушения.
EA201890020A 2015-06-15 2016-06-06 Способы и композиции для лечения ассоциированных со старением состояний EA201890020A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562175981P 2015-06-15 2015-06-15
PCT/US2016/036032 WO2016205004A2 (en) 2015-06-15 2016-06-06 Methods and compositions for treating aging-associated conditions

Publications (1)

Publication Number Publication Date
EA201890020A1 true EA201890020A1 (ru) 2018-05-31

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Family Applications (1)

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EA201890020A EA201890020A1 (ru) 2015-06-15 2016-06-06 Способы и композиции для лечения ассоциированных со старением состояний

Country Status (16)

Country Link
US (3) US10617744B2 (ru)
EP (2) EP3307296B1 (ru)
JP (3) JP6921006B2 (ru)
KR (4) KR20240025721A (ru)
CN (2) CN113855804A (ru)
AU (1) AU2016279804B2 (ru)
CA (1) CA2989138C (ru)
DK (1) DK3307296T3 (ru)
EA (1) EA201890020A1 (ru)
ES (1) ES2902467T3 (ru)
HK (1) HK1247102A1 (ru)
IL (2) IL256243B (ru)
NZ (1) NZ738675A (ru)
PT (1) PT3307296T (ru)
SI (1) SI3307296T1 (ru)
WO (1) WO2016205004A2 (ru)

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US20200254075A1 (en) 2020-08-13
US20180353578A1 (en) 2018-12-13
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