EA201791888A1 - Устройство и способ тестирования и проверки целостности контейнера - Google Patents

Устройство и способ тестирования и проверки целостности контейнера

Info

Publication number
EA201791888A1
EA201791888A1 EA201791888A EA201791888A EA201791888A1 EA 201791888 A1 EA201791888 A1 EA 201791888A1 EA 201791888 A EA201791888 A EA 201791888A EA 201791888 A EA201791888 A EA 201791888A EA 201791888 A1 EA201791888 A1 EA 201791888A1
Authority
EA
Eurasian Patent Office
Prior art keywords
light source
visual observation
holder
testing
attached
Prior art date
Application number
EA201791888A
Other languages
English (en)
Other versions
EA034400B1 (ru
Inventor
Стив Ангермунд
Джордж Карриер
Джо Джай Ку
Original Assignee
Бристол-Маерс Сквибб Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Бристол-Маерс Сквибб Компани filed Critical Бристол-Маерс Сквибб Компани
Publication of EA201791888A1 publication Critical patent/EA201791888A1/ru
Publication of EA034400B1 publication Critical patent/EA034400B1/ru

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01M—TESTING STATIC OR DYNAMIC BALANCE OF MACHINES OR STRUCTURES; TESTING OF STRUCTURES OR APPARATUS, NOT OTHERWISE PROVIDED FOR
    • G01M3/00—Investigating fluid-tightness of structures
    • G01M3/02—Investigating fluid-tightness of structures by using fluid or vacuum
    • G01M3/04—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point
    • G01M3/20—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using special tracer materials, e.g. dye, fluorescent material, radioactive material
    • G01M3/22—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using special tracer materials, e.g. dye, fluorescent material, radioactive material for pipes, cables or tubes; for pipe joints or seals; for valves; for welds; for containers, e.g. radiators
    • G01M3/226—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using special tracer materials, e.g. dye, fluorescent material, radioactive material for pipes, cables or tubes; for pipe joints or seals; for valves; for welds; for containers, e.g. radiators for containers, e.g. radiators
    • G01M3/229—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using special tracer materials, e.g. dye, fluorescent material, radioactive material for pipes, cables or tubes; for pipe joints or seals; for valves; for welds; for containers, e.g. radiators for containers, e.g. radiators removably mounted in a test cell
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01M—TESTING STATIC OR DYNAMIC BALANCE OF MACHINES OR STRUCTURES; TESTING OF STRUCTURES OR APPARATUS, NOT OTHERWISE PROVIDED FOR
    • G01M3/00—Investigating fluid-tightness of structures
    • G01M3/38—Investigating fluid-tightness of structures by using light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/88—Investigating the presence of flaws or contamination
    • G01N21/8803—Visual inspection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/88—Investigating the presence of flaws or contamination
    • G01N21/8806—Specially adapted optical and illumination features
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/88—Investigating the presence of flaws or contamination
    • G01N21/90—Investigating the presence of flaws or contamination in a container or its contents
    • G01N21/9018—Dirt detection in containers
    • G01N21/9027—Dirt detection in containers in containers after filling
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/88—Investigating the presence of flaws or contamination
    • G01N21/90—Investigating the presence of flaws or contamination in a container or its contents
    • G01N21/9054—Inspection of sealing surface and container finish
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/88—Investigating the presence of flaws or contamination
    • G01N21/91—Investigating the presence of flaws or contamination using penetration of dyes, e.g. fluorescent ink
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/06—Test-tube stands; Test-tube holders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/062—LED's
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/063—Illuminating optical parts
    • G01N2201/0638—Refractive parts

Landscapes

  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Materials By The Use Of Optical Means Adapted For Particular Applications (AREA)
  • Examining Or Testing Airtightness (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Описано контрольно-измерительное устройство и способ тестирования и проверки целостности контейнера. Контрольно-измерительное устройство содержит угловой элемент и элемент визуального наблюдения, прикрепленный к угловому элементу. Взятые вместе, угловой элемент и элемент визуального наблюдения выполнены с возможностью удерживания контейнера, подлежащего анализу. Контрольно-измерительное устройство также включает опору, прикрепленную к угловому элементу, при этом опора содержит углубление, выполненное с возможностью удерживания под углом углового элемента. Контрольно-измерительное устройство также включает держатель источника света, прикрепленный к элементу визуального наблюдения, опорную стойку, примыкающую к держателю источника света и по меньшей мере один источник света, проходящий через держатель источника света. Источник света имеет первый конец, проходящий в направлении от держателя источника света, и второй конец, проходящий внутри держателя источника света, от которого распространяется свет. Свет от источника света распространяется в направлении элемента визуального наблюдения. Элемент визуального наблюдения включает по меньшей мере одно окно визуального наблюдения. Линзы расположены между вторым концом источника света и элементом визуального наблюдения, и фильтр расположен между линзами и элементом визуального наблюдения.
EA201791888A 2015-02-23 2016-02-17 Устройство и способ тестирования герметичности заполненного лекарственным средством контейнера EA034400B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562119589P 2015-02-23 2015-02-23
PCT/US2016/018173 WO2016137789A1 (en) 2015-02-23 2016-02-17 Device and method for testing and inspecting integrity of a container

Publications (2)

Publication Number Publication Date
EA201791888A1 true EA201791888A1 (ru) 2017-12-29
EA034400B1 EA034400B1 (ru) 2020-02-04

Family

ID=55447152

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201791888A EA034400B1 (ru) 2015-02-23 2016-02-17 Устройство и способ тестирования герметичности заполненного лекарственным средством контейнера

Country Status (10)

Country Link
US (1) US10261030B2 (ru)
EP (1) EP3262400B1 (ru)
JP (1) JP6657238B2 (ru)
CN (1) CN107257921A (ru)
BR (1) BR112017016410B1 (ru)
CA (1) CA2977047C (ru)
EA (1) EA034400B1 (ru)
ES (1) ES2864762T3 (ru)
MX (1) MX2017010543A (ru)
WO (1) WO2016137789A1 (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10801913B2 (en) * 2017-09-14 2020-10-13 Lonza Ltd Device and method for improved closure integrity testing
US11353403B2 (en) 2018-11-30 2022-06-07 Genentech, Inc. Vial contents inspection and material identification method and apparatus
US10948402B2 (en) 2018-11-30 2021-03-16 Genentech, Inc. Vial inspection method and apparatus
US20220397562A1 (en) * 2020-01-17 2022-12-15 Laura RODRÍGUEZ GARCÍA Method for identifying the quality of a liquid pharmaceutical product
EP3855174B1 (en) * 2020-01-23 2024-05-15 SCHOTT Pharma Schweiz AG Detection and characterization of defects in pharmaceutical cylindrical containers
CN111896192B (zh) * 2020-08-12 2022-11-11 重庆华邦制药有限公司 一种色水法测定包装密封性的测试方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1521648A (en) * 1924-01-26 1925-01-06 Pickett James Display device
US2206728A (en) * 1939-10-20 1940-07-02 Nevins Church Press Display stand
US2479743A (en) * 1947-04-24 1949-08-23 Flemmon P Hall Leak indicator for sealed receptacles
US2917183A (en) * 1954-02-08 1959-12-15 Arthur T Seelye Holder for test tubes
US3199684A (en) * 1964-07-06 1965-08-10 Bradley Rex Lee Adjustable test tube racks
DE1573413B2 (de) * 1965-03-09 1971-02-11 Brevetti CEA SpA, Vicenza (Italien) Einrichtung zur Kontrolle von in Am pullen oder anderen durchsichtigen, roh renformigen Behaltern enthaltenen Verun reinigungen
US3751172A (en) * 1972-03-24 1973-08-07 Baxter Laboratories Inc Viewing rack
US4363551A (en) * 1976-06-01 1982-12-14 Baxter Travenol Laboratories, Inc. Nephelometer having means semiautomatically canceling components from scattering by particles smaller or larger than those of interest
US4273416A (en) * 1979-01-02 1981-06-16 Blum Alvin S Indicating test tube rack
US4278176A (en) * 1979-07-02 1981-07-14 University Of Utah Gradient tube rack and method
US4349510A (en) * 1979-07-24 1982-09-14 Seppo Kolehmainen Method and apparatus for measurement of samples by luminescence
US4382679A (en) * 1980-10-06 1983-05-10 Cutter Laboratories, Inc. Dye leak detection method
US4748125A (en) * 1986-09-25 1988-05-31 Pizzolante John M Disposable adhesive test tube rack
US4947996A (en) * 1988-05-09 1990-08-14 Harris Howard J Unitary article holder/display
US4962041A (en) * 1988-10-06 1990-10-09 Medical Automation Specialities, Inc. Method and apparatus for automatic processing and analyzing of blood serum
US5632388A (en) * 1995-01-30 1997-05-27 Forma Scientific, Inc. Test tube rack assembly
JP2000245500A (ja) * 1998-12-28 2000-09-12 Kikkoman Corp 発光による試料の測定方法及び装置
US6646741B1 (en) * 2002-05-24 2003-11-11 Spectrex Corporation Method and apparatus for visualizing particles suspended in a fluid
US20050095717A1 (en) * 2003-10-31 2005-05-05 Wollenberg Robert H. High throughput screening methods for lubricating oil compositions
JP3908744B2 (ja) * 2004-03-08 2007-04-25 株式会社アイディエス 試験管のバーコード読取り装置
US8789713B2 (en) * 2012-07-23 2014-07-29 Charles Koller Surgical instrument caddy
US9907727B2 (en) * 2012-10-30 2018-03-06 Gary L. Sharpe Vial gripper
WO2014081818A1 (en) * 2012-11-20 2014-05-30 Tripath Imaging, Inc. Offset sample tube holder

Also Published As

Publication number Publication date
JP6657238B2 (ja) 2020-03-04
EP3262400A1 (en) 2018-01-03
BR112017016410A2 (pt) 2018-03-27
CA2977047A1 (en) 2016-09-01
CA2977047C (en) 2023-03-21
JP2018509606A (ja) 2018-04-05
EA034400B1 (ru) 2020-02-04
WO2016137789A1 (en) 2016-09-01
ES2864762T3 (es) 2021-10-14
US10261030B2 (en) 2019-04-16
US20180045653A1 (en) 2018-02-15
CN107257921A (zh) 2017-10-17
EP3262400B1 (en) 2021-03-24
MX2017010543A (es) 2017-12-14
BR112017016410B1 (pt) 2022-01-04

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Legal Events

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG TJ TM