DK3377878T3 - Optisk sensor til detektering af frit hæmoglobin i en helblods prøve - Google Patents
Optisk sensor til detektering af frit hæmoglobin i en helblods prøve Download PDFInfo
- Publication number
- DK3377878T3 DK3377878T3 DK16801733.3T DK16801733T DK3377878T3 DK 3377878 T3 DK3377878 T3 DK 3377878T3 DK 16801733 T DK16801733 T DK 16801733T DK 3377878 T3 DK3377878 T3 DK 3377878T3
- Authority
- DK
- Denmark
- Prior art keywords
- optical sensor
- whole blood
- blood test
- free hemoglobin
- detecting free
- Prior art date
Links
- 102000001554 Hemoglobins Human genes 0.000 title 1
- 108010054147 Hemoglobins Proteins 0.000 title 1
- 238000009534 blood test Methods 0.000 title 1
- 230000003287 optical effect Effects 0.000 title 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/491—Blood by separating the blood components
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/728—Bilirubin; including biliverdin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0357—Sets of cuvettes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/06—Illumination; Optics
- G01N2201/061—Sources
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Biophysics (AREA)
- Ecology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Optical Measuring Cells (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA201500740 | 2015-11-18 | ||
PCT/EP2016/077990 WO2017085180A1 (en) | 2015-11-18 | 2016-11-17 | Optical sensor for detection of free hemoglobin in a whole blood sample |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3377878T3 true DK3377878T3 (da) | 2020-03-02 |
Family
ID=58717407
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK16798144.8T DK3377877T3 (da) | 2015-11-18 | 2016-11-17 | Porefyldt spejl til optisk detektering af en analyt i en fluid |
DK16801733.3T DK3377878T3 (da) | 2015-11-18 | 2016-11-17 | Optisk sensor til detektering af frit hæmoglobin i en helblods prøve |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK16798144.8T DK3377877T3 (da) | 2015-11-18 | 2016-11-17 | Porefyldt spejl til optisk detektering af en analyt i en fluid |
Country Status (7)
Country | Link |
---|---|
US (3) | US10663395B2 (da) |
EP (3) | EP3377877B1 (da) |
JP (2) | JP6725656B2 (da) |
KR (2) | KR102093684B1 (da) |
CN (2) | CN108351292A (da) |
DK (2) | DK3377877T3 (da) |
WO (2) | WO2017085180A1 (da) |
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US10663395B2 (en) * | 2015-11-18 | 2020-05-26 | Radiometer Medical Aps | Porous mirror for optical detection of an analyte in a fluid |
MX2020010523A (es) | 2017-02-27 | 2021-02-09 | Third Pole Inc | Sistemas y metodos para generar oxido nitrico. |
CA3054660C (en) | 2017-02-27 | 2022-05-03 | Third Pole, Inc. | Systems and methods for ambulatory generation of nitric oxide |
WO2019033221A1 (en) | 2017-08-18 | 2019-02-21 | Somadetect Inc. | METHODS AND SYSTEMS FOR ASSESSING THE HEALTH STATUS OF A LACTATION MAMMAL |
JP7015521B2 (ja) * | 2017-11-09 | 2022-02-03 | 国立大学法人弘前大学 | 全血アルブミン分析装置および全血アルブミン分析方法 |
WO2019197308A1 (en) | 2018-04-12 | 2019-10-17 | Radiometer Medical Aps | Porous membrane sensor element |
CA3108774C (en) * | 2018-08-06 | 2024-02-27 | Siemens Healthcare Diagnostics Inc. | Method, device and system for determining the concentration of analytes in a sample |
CN115508568A (zh) * | 2019-01-29 | 2022-12-23 | 美国西门子医学诊断股份有限公司 | 降低血红蛋白A1c测定中的英脱利匹特/脂血干扰的浊度归一化算法和方法 |
EP3969415A4 (en) | 2019-05-15 | 2023-08-16 | Third Pole, Inc. | ELECTRODES FOR NITRIC OXIDE GENERATION |
EP3969416A4 (en) | 2019-05-15 | 2023-11-01 | Third Pole, Inc. | SYSTEMS AND METHODS FOR GENERATING NITRIC OXIDE |
WO2021123441A1 (en) | 2019-12-19 | 2021-06-24 | Radiometer Medical Aps | Sensor assembly and porous membrane sensor element |
WO2021123442A1 (en) | 2019-12-19 | 2021-06-24 | Radiometer Medical Aps | Porous membrane sensor assembly |
EP4069069A1 (en) | 2020-01-11 | 2022-10-12 | Third Pole, Inc. | Systems and methods for nitric oxide generation with humidity control |
US20210395905A1 (en) * | 2020-06-18 | 2021-12-23 | Third Pole, Inc. | Systems and methods for preventing and treating infections with nitric oxide |
JP2024502763A (ja) * | 2020-12-22 | 2024-01-23 | ラジオメーター・メディカル・アー・ペー・エス | 光学分析物測定のための反射層なしの多孔性ユニット |
CN116888453A (zh) * | 2020-12-22 | 2023-10-13 | 雷迪奥米特医学公司 | 确定液体中分析物的时间响应值 |
WO2022136327A1 (en) | 2020-12-22 | 2022-06-30 | Radiometer Medical Aps | Determining interference criticality based on analyte and cell-free hemoglobin concentrations |
US20240044790A1 (en) * | 2020-12-22 | 2024-02-08 | Radiometer Medical Aps | Determining time response value of an analyte in a liquid |
CN116964431A (zh) | 2021-01-15 | 2023-10-27 | 雷迪奥米特医学公司 | 用于确定流体的参数的方法和系统 |
WO2023049873A1 (en) | 2021-09-23 | 2023-03-30 | Third Pole, Inc. | Systems and methods for delivering nitric oxide |
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2016
- 2016-11-17 US US15/776,469 patent/US10663395B2/en active Active
- 2016-11-17 DK DK16798144.8T patent/DK3377877T3/da active
- 2016-11-17 KR KR1020187017295A patent/KR102093684B1/ko active IP Right Grant
- 2016-11-17 DK DK16801733.3T patent/DK3377878T3/da active
- 2016-11-17 EP EP16798144.8A patent/EP3377877B1/en active Active
- 2016-11-17 JP JP2018521232A patent/JP6725656B2/ja active Active
- 2016-11-17 CN CN201680064651.4A patent/CN108351292A/zh active Pending
- 2016-11-17 US US15/776,237 patent/US11079317B2/en active Active
- 2016-11-17 WO PCT/EP2016/077990 patent/WO2017085180A1/en active Application Filing
- 2016-11-17 CN CN201680064755.5A patent/CN108463711A/zh active Pending
- 2016-11-17 JP JP2018521223A patent/JP6626196B2/ja active Active
- 2016-11-17 KR KR1020187017292A patent/KR102111937B1/ko active IP Right Grant
- 2016-11-17 EP EP19218950.4A patent/EP3654017A1/en active Pending
- 2016-11-17 EP EP16801733.3A patent/EP3377878B1/en active Active
- 2016-11-17 WO PCT/EP2016/077943 patent/WO2017085162A1/en active Application Filing
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2020
- 2020-04-21 US US16/854,136 patent/US11079319B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
KR20180084939A (ko) | 2018-07-25 |
US20200249151A1 (en) | 2020-08-06 |
KR20180083420A (ko) | 2018-07-20 |
US10663395B2 (en) | 2020-05-26 |
KR102093684B1 (ko) | 2020-03-27 |
EP3377878B1 (en) | 2019-12-25 |
EP3377877A1 (en) | 2018-09-26 |
CN108351292A (zh) | 2018-07-31 |
EP3377878A1 (en) | 2018-09-26 |
US20180328842A1 (en) | 2018-11-15 |
WO2017085180A1 (en) | 2017-05-26 |
DK3377877T3 (da) | 2020-03-23 |
WO2017085162A1 (en) | 2017-05-26 |
EP3654017A1 (en) | 2020-05-20 |
KR102111937B1 (ko) | 2020-05-19 |
JP2018533012A (ja) | 2018-11-08 |
JP6626196B2 (ja) | 2019-12-25 |
EP3377877B1 (en) | 2019-12-25 |
JP2018533011A (ja) | 2018-11-08 |
US11079319B2 (en) | 2021-08-03 |
US11079317B2 (en) | 2021-08-03 |
US20200256845A1 (en) | 2020-08-13 |
JP6725656B2 (ja) | 2020-07-22 |
CN108463711A (zh) | 2018-08-28 |
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