KR20180084939A - 유체 중 피분석물의 광학 검출을 위한 다공성 미러 - Google Patents

유체 중 피분석물의 광학 검출을 위한 다공성 미러 Download PDF

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KR20180084939A
KR20180084939A KR1020187017292A KR20187017292A KR20180084939A KR 20180084939 A KR20180084939 A KR 20180084939A KR 1020187017292 A KR1020187017292 A KR 1020187017292A KR 20187017292 A KR20187017292 A KR 20187017292A KR 20180084939 A KR20180084939 A KR 20180084939A
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analytes
fluid
optical detection
mirrors
porous
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KR1020187017292A
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KR102111937B1 (ko
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토마스 키예르
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라디오미터 메디컬 에이피에스
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/491Blood by separating the blood components
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721Haemoglobin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/728Bilirubin; including biliverdin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N2021/0357Sets of cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/06Illumination; Optics
    • G01N2201/061Sources

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Ecology (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Optical Measuring Cells (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
KR1020187017292A 2015-11-18 2016-11-17 유체 중 피분석물의 광학 검출을 위한 다공성 미러 KR102111937B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA201500740 2015-11-18
DKPA201500740 2015-11-18
PCT/EP2016/077943 WO2017085162A1 (en) 2015-11-18 2016-11-17 Porous mirror for optical detection of an analyte in a fluid

Publications (2)

Publication Number Publication Date
KR20180084939A true KR20180084939A (ko) 2018-07-25
KR102111937B1 KR102111937B1 (ko) 2020-05-19

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KR1020187017292A KR102111937B1 (ko) 2015-11-18 2016-11-17 유체 중 피분석물의 광학 검출을 위한 다공성 미러
KR1020187017295A KR102093684B1 (ko) 2015-11-18 2016-11-17 전혈 샘플 중 자유 헤모글로빈의 검출을 위한 광학 센서

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US (3) US10663395B2 (ko)
EP (3) EP3654017A1 (ko)
JP (2) JP6626196B2 (ko)
KR (2) KR102111937B1 (ko)
CN (2) CN108351292A (ko)
DK (2) DK3377877T3 (ko)
WO (2) WO2017085162A1 (ko)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6626196B2 (ja) * 2015-11-18 2019-12-25 ラジオメーター・メディカル・アー・ペー・エス 流体中の検体を光学的に検出するための多孔質ミラー
MX2020010523A (es) 2017-02-27 2021-02-09 Third Pole Inc Sistemas y metodos para generar oxido nitrico.
WO2018157175A1 (en) 2017-02-27 2018-08-30 Third Pole, Inc. Systems and methods for ambulatory generation of nitric oxide
CN111344555B (zh) 2017-08-18 2024-05-07 索马检测有限公司 评估泌乳哺乳动物的健康状态的方法和系统
JP7015521B2 (ja) * 2017-11-09 2022-02-03 国立大学法人弘前大学 全血アルブミン分析装置および全血アルブミン分析方法
US20210015409A1 (en) 2018-04-12 2021-01-21 Radiometer Medical Aps Porous membrane sensor element
EP3833962A4 (en) * 2018-08-06 2022-01-05 Siemens Healthcare Diagnostics Inc. METHOD, DEVICE AND SYSTEM FOR DETERMINING THE CONCENTRATION OF ANALYTES IN A SAMPLE
CN115508568A (zh) 2019-01-29 2022-12-23 美国西门子医学诊断股份有限公司 降低血红蛋白A1c测定中的英脱利匹特/脂血干扰的浊度归一化算法和方法
US11479464B2 (en) 2019-05-15 2022-10-25 Third Pole, Inc. Systems and methods for generating nitric oxide
JP2022533628A (ja) 2019-05-15 2022-07-25 サード ポール,インコーポレイテッド 一酸化窒素生成用電極
EP4078152A1 (en) 2019-12-19 2022-10-26 Radiometer Medical ApS Sensor assembly and porous membrane sensor element
CN114829910A (zh) 2019-12-19 2022-07-29 雷迪奥米特医学公司 多孔膜传感器组件
WO2021142472A1 (en) 2020-01-11 2021-07-15 Third Pole, Inc. Systems and methods for nitric oxide generation with humidity control
US20210395905A1 (en) * 2020-06-18 2021-12-23 Third Pole, Inc. Systems and methods for preventing and treating infections with nitric oxide
CN116868058A (zh) 2020-12-22 2023-10-10 雷迪奥米特医学公司 基于分析物和无细胞血红蛋白浓度确定干扰临界
US20240027475A1 (en) * 2020-12-22 2024-01-25 Radiometer Medical Aps Porous unit without reflective layer for optical analyte measurements
JP2024500236A (ja) * 2020-12-22 2024-01-05 ラジオメーター・メディカル・アー・ペー・エス 液体中の分析物の時間応答値の決定
CN116888453A (zh) * 2020-12-22 2023-10-13 雷迪奥米特医学公司 确定液体中分析物的时间响应值
EP4278170A1 (en) 2021-01-15 2023-11-22 Radiometer Medical ApS A method of and a system for determining a parameter of a fluid
WO2023049873A1 (en) 2021-09-23 2023-03-30 Third Pole, Inc. Systems and methods for delivering nitric oxide
WO2023099752A1 (en) 2021-12-03 2023-06-08 Radiometer Medical Aps Method to determine impact on analytes due to cytolysis in a sample
WO2023118079A1 (en) * 2021-12-23 2023-06-29 Hemocue Ab Method and analyzer for analyzing a blood sample

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005062986A2 (en) * 2003-12-31 2005-07-14 The University Of South Carolina Thin-layer porous optical sensors for gases and other fluids
JP2012522249A (ja) * 2009-03-30 2012-09-20 スリーエム イノベイティブ プロパティズ カンパニー 検体の検出のための光電子法及びデバイス
WO2014105070A1 (en) * 2012-12-28 2014-07-03 Halliburton Energy Services Inc. Optically transparent films for measuring optically thick fluids

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2090659A (en) 1981-01-02 1982-07-14 Instrumentation Labor Inc Analytical device
JPS59214765A (ja) * 1983-05-20 1984-12-04 Mochida Pharmaceut Co Ltd 血漿分離装置とその使用方法
AU4287593A (en) * 1992-04-27 1993-11-29 Avocet Medical, Inc. Test article and method for performing blood coagulation assays
US5580744A (en) * 1992-04-27 1996-12-03 Avocet Medical, Inc. Test article and method for performing blood coagulation assays
US6040191A (en) * 1996-06-13 2000-03-21 Grow; Ann E. Raman spectroscopic method for determining the ligand binding capacity of biologicals
JP2000515778A (ja) * 1996-07-08 2000-11-28 アニマス コーポレーシヨン 体液成分レベルの生体内測定および制御のための埋込可能センサーおよびシステム
JP3918952B2 (ja) * 1997-03-03 2007-05-23 シーエムイー テレメトリクス インコーポレーテッド ドナー血液バッグからの血漿中の干渉体について血漿を検査する方法および装置
US5859937A (en) * 1997-04-04 1999-01-12 Neomecs Incorporated Minimally invasive sensor
US20030235920A1 (en) * 2000-02-28 2003-12-25 James Wyatt Diagnostic device and method
JP3863373B2 (ja) * 1999-03-02 2006-12-27 クオリジエン・インコーポレイテツド 生物学的流体の分離のための装置を用いる方法
US6690467B1 (en) * 2000-05-05 2004-02-10 Pe Corporation Optical system and method for optically analyzing light from a sample
IL157047A0 (en) * 2001-01-31 2004-02-08 Scripps Lab Methods and devices for quantitation of glycated protein
US6753187B2 (en) 2001-05-09 2004-06-22 Lifescan, Inc. Optical component based temperature measurement in analyte detection devices
WO2003030621A2 (en) * 2001-10-11 2003-04-17 Sentelligence, Inc. Low-cost on-line and in-line spectral sensors based on solid-state source and detector combinations
GB0207943D0 (en) 2002-04-05 2002-05-15 Univ Cambridge Tech Sensors and their production
JP2004532338A (ja) 2002-05-21 2004-10-21 バセル ポリオレフィン イタリア エス.ピー.エー. ポリプロピレン系樹脂組成物
DE10223450A1 (de) 2002-05-23 2003-12-04 Laser & Med Tech Gmbh Optisches Verfahren zur Bestimmung des extrazellulären Hämoglobingehaltes in Blutkonserven
US7379167B2 (en) 2003-02-11 2008-05-27 International Technidyne Corporation Hemoglobin test strip and analysis system
ATE521881T1 (de) * 2003-12-19 2011-09-15 Medair Ab Flüssigkeits- oder gassensor und verfahren
US7781226B2 (en) * 2004-02-27 2010-08-24 The Board Of Regents Of The University Of Texas System Particle on membrane assay system
US20060257854A1 (en) 2004-02-27 2006-11-16 Mcdevitt John T Membrane assay system including preloaded particles
DE602004011688D1 (de) * 2004-03-05 2008-03-20 Egomedical Swiss Ag Analyttestsystem zur bestimmung der konzentration eines analyten in einer physiologischen flüssigkeit
US7959791B2 (en) * 2005-05-17 2011-06-14 Radiometer Medical Aps Enzyme sensor with a cover membrane layer covered by a hydrophilic polymer
CN1975377A (zh) * 2005-11-28 2007-06-06 中国科学院电子学研究所 光学快速检测血红蛋白用生物传感器
US7906223B2 (en) * 2006-09-11 2011-03-15 3M Innovative Properties Company Permeable nanoparticle reflector
US8958070B2 (en) * 2007-05-29 2015-02-17 OptoTrace (SuZhou) Technologies, Inc. Multi-layer variable micro structure for sensing substance
EP2285267A1 (en) * 2008-03-31 2011-02-23 P&V Consulting GmbH & Co. KG. Optic sensor device with sers
EP2157418A1 (en) * 2008-07-02 2010-02-24 Koninklijke Philips Electronics N.V. Fluid providing apparatus
US20100159498A1 (en) * 2008-12-19 2010-06-24 Ritzen Kalle Blood analyzer with a blood cell sedimentation control mechanism and method of use
JP5399101B2 (ja) 2009-03-05 2014-01-29 本田技研工業株式会社 試料保持部材
WO2010147251A1 (ko) 2009-06-19 2010-12-23 주식회사 인포피아 당화혈색소 측정 방법
CN102834717B (zh) * 2010-04-07 2015-05-27 英派尔科技开发有限公司 用于检测水或水溶液中的污染物的检测器
WO2011155897A1 (en) 2010-06-10 2011-12-15 Hemcheck Sweden Aktiebolag Arrangement for detection of hemolysis
DE102010024964B4 (de) * 2010-06-24 2012-01-26 Siemens Aktiengesellschaft Zellüberwachung mittels Streulichtmessung
CN102985804B (zh) * 2010-07-09 2016-06-01 皇家飞利浦电子股份有限公司 具有大规模制造设计的盒
TWI456195B (zh) * 2011-01-27 2014-10-11 Univ Nat Cheng Kung 生醫及微奈米結構物質感測晶片及其製備方法
JP5724497B2 (ja) * 2011-03-18 2015-05-27 セイコーエプソン株式会社 物質成分検出装置
MX2013014553A (es) * 2011-06-30 2014-02-19 Koninkl Philips Nv Examenes multiples de una muestra.
SE536634C2 (sv) 2011-12-09 2014-04-15 Hemcheck Sweden Ab Anordning för detektion av hemolys
US20140327909A1 (en) * 2011-12-16 2014-11-06 Mikael Käll Method for exciting a sub-wavelength inclusion structure
WO2013096817A2 (en) 2011-12-23 2013-06-27 Abbott Point Of Care Inc Integrated test device for optical detection of microarrays
JP5901012B2 (ja) * 2012-02-13 2016-04-06 国立大学法人 東京医科歯科大学 血液情報の測定方法及び装置
JP5935492B2 (ja) * 2012-05-01 2016-06-15 セイコーエプソン株式会社 光学デバイス及び検出装置
US9366662B2 (en) * 2012-06-05 2016-06-14 Siemens Healthcare Diagnostics Inc. Serum sample quality determination
US20140193892A1 (en) 2012-07-25 2014-07-10 Theranos, Inc. Image analysis and measurement of biological samples
EP2883047A1 (en) 2012-08-08 2015-06-17 Koninklijke Philips N.V. Method and apparatus for separating plasma from blood for bilirubin level estimation.
US9097616B2 (en) * 2013-01-25 2015-08-04 Hewlett-Packard Development Company, L.P. Apparatus for collecting material to be spectrally analyzed
WO2015010709A1 (en) * 2013-07-22 2015-01-29 Sentec Ag Sensor for detection of gas and method for detection of gas
DE102013018284B4 (de) 2013-10-31 2015-08-27 Fresenius Medical Care Deutschland Gmbh Verfahren und Vorrichtung zur Erfassung der Hämolyse oder zur Bestimmung eines den Einfluss der Hämolyse auf eine Messung des Hämatokrits korrigierenden Korrekturfaktors
CA2953222C (en) 2014-06-13 2022-04-05 Siemens Healthcare Diagnostics Inc. Detection of hemolysis using a chromatographic detection pad
GB2530486B (en) * 2014-09-15 2017-08-02 Schlumberger Holdings Active surface cleaning for a sensor
JP6626196B2 (ja) * 2015-11-18 2019-12-25 ラジオメーター・メディカル・アー・ペー・エス 流体中の検体を光学的に検出するための多孔質ミラー

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005062986A2 (en) * 2003-12-31 2005-07-14 The University Of South Carolina Thin-layer porous optical sensors for gases and other fluids
JP2012522249A (ja) * 2009-03-30 2012-09-20 スリーエム イノベイティブ プロパティズ カンパニー 検体の検出のための光電子法及びデバイス
WO2014105070A1 (en) * 2012-12-28 2014-07-03 Halliburton Energy Services Inc. Optically transparent films for measuring optically thick fluids

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Paul G Miney 외 'A New Optically Reflective Thin Layer Electrode Window'(Electroanlaysis Vol.16, 2004.12.31.) pp113~119. *

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Publication number Publication date
JP6626196B2 (ja) 2019-12-25
EP3654017A1 (en) 2020-05-20
KR102093684B1 (ko) 2020-03-27
CN108351292A (zh) 2018-07-31
US11079317B2 (en) 2021-08-03
DK3377878T3 (da) 2020-03-02
EP3377878B1 (en) 2019-12-25
KR20180083420A (ko) 2018-07-20
US20180328842A1 (en) 2018-11-15
DK3377877T3 (da) 2020-03-23
US20200256845A1 (en) 2020-08-13
KR102111937B1 (ko) 2020-05-19
CN108463711A (zh) 2018-08-28
JP6725656B2 (ja) 2020-07-22
EP3377878A1 (en) 2018-09-26
EP3377877A1 (en) 2018-09-26
US10663395B2 (en) 2020-05-26
JP2018533011A (ja) 2018-11-08
US11079319B2 (en) 2021-08-03
WO2017085180A1 (en) 2017-05-26
US20200249151A1 (en) 2020-08-06
EP3377877B1 (en) 2019-12-25
WO2017085162A1 (en) 2017-05-26
JP2018533012A (ja) 2018-11-08

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