EA201700097A1 - Пептид для лечения сахарного диабета 2-го типа и его осложнений - Google Patents

Пептид для лечения сахарного диабета 2-го типа и его осложнений

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Publication number
EA201700097A1
EA201700097A1 EA201700097A EA201700097A EA201700097A1 EA 201700097 A1 EA201700097 A1 EA 201700097A1 EA 201700097 A EA201700097 A EA 201700097A EA 201700097 A EA201700097 A EA 201700097A EA 201700097 A1 EA201700097 A1 EA 201700097A1
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EA
Eurasian Patent Office
Prior art keywords
arg
gly
glu
ser
diabetes
Prior art date
Application number
EA201700097A
Other languages
English (en)
Inventor
Михаил Иванович Титов
Иван Иванович Елисеев
Валерий Геннадьевич МАКАРОВ
Марина Николаевна МАКАРОВА
Елена Васильевна Шекунова
Владимир Александрович Кашкин
Original Assignee
Дафот Энтерпрайсис Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Дафот Энтерпрайсис Лимитед filed Critical Дафот Энтерпрайсис Лимитед
Publication of EA201700097A1 publication Critical patent/EA201700097A1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/15—Corynebacterium

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)

Abstract

Изобретение относится к биотехнологии. Представлен аналог эксенатида формулы H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Gly-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-Gly-OH. Изобретение позволяет лечить и проводить профилактику сахарного диабета, а также лечить и проводить профилактику осложнений сахарного диабета 2-го типа, таких как диабетическая нейропатия, мышечная дистрофия и эндотелиопатия.
EA201700097A 2014-08-21 2015-08-04 Пептид для лечения сахарного диабета 2-го типа и его осложнений EA201700097A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2014134341/10A RU2573933C1 (ru) 2014-08-21 2014-08-21 Пептид для лечения сахарного диабета 2-го типа и его осложнений
PCT/IB2015/001614 WO2016027157A1 (en) 2014-08-21 2015-08-04 Peptide for treatment of type 2 diabetes mellitus and its complications

Publications (1)

Publication Number Publication Date
EA201700097A1 true EA201700097A1 (ru) 2017-06-30

Family

ID=54292830

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201700097A EA201700097A1 (ru) 2014-08-21 2015-08-04 Пептид для лечения сахарного диабета 2-го типа и его осложнений

Country Status (12)

Country Link
US (1) US9868773B2 (ru)
EP (1) EP3183265B1 (ru)
JP (1) JP6442729B2 (ru)
KR (1) KR102003619B1 (ru)
CN (1) CN106574233A (ru)
AU (1) AU2015304934B2 (ru)
CA (1) CA2958795C (ru)
EA (1) EA201700097A1 (ru)
ES (1) ES2711841T3 (ru)
IL (1) IL250666B (ru)
RU (1) RU2573933C1 (ru)
WO (1) WO2016027157A1 (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102408480B1 (ko) 2018-05-30 2022-06-10 이삼구 당뇨질환의 치료용 조성물
WO2024077149A2 (en) * 2022-10-05 2024-04-11 Eli Lilly And Company Peptides for incretin synthesis

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Also Published As

Publication number Publication date
EP3183265B1 (en) 2018-09-26
KR20170041914A (ko) 2017-04-17
JP2017525764A (ja) 2017-09-07
RU2573933C1 (ru) 2016-01-27
CA2958795C (en) 2021-01-12
KR102003619B1 (ko) 2019-07-24
US20170240610A1 (en) 2017-08-24
IL250666B (en) 2021-10-31
IL250666A0 (en) 2017-04-30
CA2958795A1 (en) 2016-02-25
EP3183265A1 (en) 2017-06-28
JP6442729B2 (ja) 2018-12-26
US9868773B2 (en) 2018-01-16
WO2016027157A1 (en) 2016-02-25
ES2711841T3 (es) 2019-05-07
AU2015304934B2 (en) 2018-05-10
CN106574233A (zh) 2017-04-19
AU2015304934A1 (en) 2017-03-09

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