EA201590738A1 - Ингалятор сухого порошка - Google Patents

Ингалятор сухого порошка

Info

Publication number
EA201590738A1
EA201590738A1 EA201590738A EA201590738A EA201590738A1 EA 201590738 A1 EA201590738 A1 EA 201590738A1 EA 201590738 A EA201590738 A EA 201590738A EA 201590738 A EA201590738 A EA 201590738A EA 201590738 A1 EA201590738 A1 EA 201590738A1
Authority
EA
Eurasian Patent Office
Prior art keywords
drug
dry powder
microns
lactose
container
Prior art date
Application number
EA201590738A
Other languages
English (en)
Other versions
EA034245B1 (ru
Inventor
Ян Арп
Йохан Кегстра
Майкл Имре Голлер
Original Assignee
Фармахеми Б.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Фармахеми Б.В. filed Critical Фармахеми Б.В.
Publication of EA201590738A1 publication Critical patent/EA201590738A1/ru
Publication of EA034245B1 publication Critical patent/EA034245B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
    • A61M15/0008—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows

Abstract

В изобретении предложен ингалятор сухого порошка будесонида и формотерола, содержащий емкость для лекарственного средства в виде сухого порошка и приспособление для подачи измеренной дозы лекарственного средства из емкости; циклонный деагломератор для разрушения агломератов лекарственного средства в виде сухого порошка; проточный канал подачи для направления потока воздуха, вызываемого вдыханием, через мундштук, причем проточный канал подачи проходит до измеренной дозы лекарственного средства, при этом лекарственное средство содержит тонкоизмельченный формотерола фумарат, тонкоизмельченный будесонид и носитель в виде лактозы, причем носитель в виде лактозы имеет следующее распределение размеров частиц: d10=20-65 мкм, d50=80-120 мкм, d90=130-180 мкм и <10 мкм ≤10%.
EA201590738A 2013-12-09 2014-11-19 Фармацевтическая композиция для вдыхания для лечения респираторного заболевания, её применение и способ лечения респираторного заболевания EA034245B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1321712.0A GB201321712D0 (en) 2013-12-09 2013-12-09 Dry Powder Inhaler
PCT/EP2014/075043 WO2015086276A1 (en) 2013-12-09 2014-11-19 Dry powder inhaler

Publications (2)

Publication Number Publication Date
EA201590738A1 true EA201590738A1 (ru) 2015-09-30
EA034245B1 EA034245B1 (ru) 2020-01-21

Family

ID=50000399

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201590738A EA034245B1 (ru) 2013-12-09 2014-11-19 Фармацевтическая композиция для вдыхания для лечения респираторного заболевания, её применение и способ лечения респираторного заболевания

Country Status (21)

Country Link
US (2) US11020546B2 (ru)
EP (2) EP3398638B1 (ru)
JP (2) JP6450388B2 (ru)
KR (2) KR102296835B1 (ru)
CN (2) CN105813675B (ru)
AR (1) AR098640A1 (ru)
AU (2) AU2014361085B2 (ru)
BR (1) BR112016011996B1 (ru)
CA (1) CA2931165A1 (ru)
DK (2) DK3398638T3 (ru)
EA (1) EA034245B1 (ru)
ES (2) ES2871820T3 (ru)
GB (1) GB201321712D0 (ru)
HU (2) HUE039641T2 (ru)
IL (2) IL246044B (ru)
MX (1) MX2016007182A (ru)
PL (2) PL3398638T3 (ru)
PT (1) PT3398638T (ru)
TR (1) TR201810066T4 (ru)
TW (1) TWI592180B (ru)
WO (1) WO2015086276A1 (ru)

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GB201321712D0 (en) 2013-12-09 2014-01-22 Pharmachemie Bv Dry Powder Inhaler
GB201321717D0 (en) * 2013-12-09 2014-01-22 Pharmachemie Bv Inhalable Medicaments
WO2016089981A1 (en) * 2014-12-04 2016-06-09 Carefusion 2200, Inc. Breath-actuated nebulizer for medicine inhalation
USD852947S1 (en) * 2016-10-21 2019-07-02 Norton (Waterford) Limited Inhaler
USD832998S1 (en) * 2016-10-21 2018-11-06 Norton (Waterford) Limited Inhaler
USD832997S1 (en) * 2016-10-21 2018-11-06 Norton (Waterford) Limited Inhaler
US11000653B2 (en) * 2016-11-18 2021-05-11 Norton (Waterford) Limited Inhaler
EP3552645A1 (en) 2016-11-18 2019-10-16 Norton (Waterford) Limited Drug delivery device with electronics
USD853555S1 (en) * 2017-01-03 2019-07-09 Norton (Waterford) Limited Inhaler
CN107715264B (zh) * 2017-10-12 2021-01-29 上海新黄河制药有限公司 一种粉雾剂装置制剂粉末团聚物的分散/解聚装置
CN107737393B (zh) * 2017-10-12 2020-08-28 上海新黄河制药有限公司 一种用于粉雾剂吸入装置的制剂雾化流道
CN110201281B (zh) * 2018-02-28 2021-08-06 张江 吸入给药装置和吸入给药组合结构
USD960349S1 (en) 2019-02-04 2022-08-09 Orion Corporation Inhaler
KR20220010741A (ko) * 2019-05-17 2022-01-26 노턴 (워터포드) 리미티드 전자 장치를 구비한 의약품 전달 장치
USD948703S1 (en) * 2019-07-26 2022-04-12 Lupin Ltd. Inhaler
USD949324S1 (en) * 2019-07-26 2022-04-19 Lupin Ltd. Inhaler
USD948704S1 (en) * 2019-07-26 2022-04-12 Lupin Ltd. Inhaler
USD949323S1 (en) * 2019-07-26 2022-04-19 Lupin Ltd. Inhaler
KR102354664B1 (ko) 2020-01-07 2022-01-24 제이디코스파마 주식회사 약제 흡입기
KR102420393B1 (ko) 2020-05-28 2022-07-13 제이디코스파마 주식회사 약제 기화 흡입기
KR102494694B1 (ko) 2020-11-10 2023-02-01 권오석 약제 기화 흡입기
USD1001996S1 (en) * 2020-12-16 2023-10-17 Alfred Von Schuckmann Inhaler
GB202102026D0 (en) * 2021-02-12 2021-03-31 Cambridge Healthcare Innovations Ltd Medical apparatus and method
US11925749B2 (en) * 2021-03-18 2024-03-12 Funai Electric Co., Ltd. Venting of pharmaceutical drug delivery device for air flow and humidity control
CN114632235B (zh) * 2022-03-04 2023-04-25 华中科技大学 一种干粉吸入器

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Also Published As

Publication number Publication date
PL3079744T3 (pl) 2018-12-31
CN105813675A (zh) 2016-07-27
CN105813675B (zh) 2019-12-13
IL246044A0 (en) 2016-07-31
EP3079744A1 (en) 2016-10-19
US11642475B2 (en) 2023-05-09
NZ721308A (en) 2022-03-25
EP3079744B1 (en) 2018-07-04
CN110812634A (zh) 2020-02-21
JP2019055257A (ja) 2019-04-11
IL272629B (en) 2021-12-01
HUE039641T2 (hu) 2019-01-28
BR112016011996B1 (pt) 2023-01-10
IL246044B (en) 2020-02-27
ES2679523T3 (es) 2018-08-28
DK3079744T3 (en) 2018-08-06
KR20160105800A (ko) 2016-09-07
CA2931165A1 (en) 2015-06-18
MX2016007182A (es) 2016-10-26
IL272629A (en) 2020-03-31
US20160303336A1 (en) 2016-10-20
AU2018226472A1 (en) 2018-09-27
CN110812634B (zh) 2022-06-03
DK3398638T3 (da) 2021-05-25
GB201321712D0 (en) 2014-01-22
JP2017500105A (ja) 2017-01-05
PT3398638T (pt) 2021-06-01
EP3398638A1 (en) 2018-11-07
AU2018226472B2 (en) 2020-03-19
PL3398638T3 (pl) 2021-08-30
TW201531313A (zh) 2015-08-16
JP6450388B2 (ja) 2019-01-09
KR20210108500A (ko) 2021-09-02
WO2015086276A1 (en) 2015-06-18
AU2014361085B2 (en) 2018-06-14
HUE055451T2 (hu) 2021-11-29
AR098640A1 (es) 2016-06-01
US20210353881A1 (en) 2021-11-18
KR102460197B1 (ko) 2022-10-28
EP3398638B1 (en) 2021-04-28
AU2014361085A1 (en) 2016-07-07
US11020546B2 (en) 2021-06-01
EA034245B1 (ru) 2020-01-21
TWI592180B (zh) 2017-07-21
BR112016011996A2 (pt) 2018-05-22
ES2871820T3 (es) 2021-11-02
KR102296835B1 (ko) 2021-09-02
JP6907178B2 (ja) 2021-07-21
TR201810066T4 (tr) 2018-08-27

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KG TJ TM