WO2015027847A3 - 含有奥司他韦羧酸胍基类似体和/或其乙酯制剂的给药方法 - Google Patents

含有奥司他韦羧酸胍基类似体和/或其乙酯制剂的给药方法 Download PDF

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Publication number
WO2015027847A3
WO2015027847A3 PCT/CN2014/084835 CN2014084835W WO2015027847A3 WO 2015027847 A3 WO2015027847 A3 WO 2015027847A3 CN 2014084835 W CN2014084835 W CN 2014084835W WO 2015027847 A3 WO2015027847 A3 WO 2015027847A3
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WO
WIPO (PCT)
Prior art keywords
guanidino
analogues
preparation containing
ethyl esters
administration method
Prior art date
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PCT/CN2014/084835
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English (en)
French (fr)
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WO2015027847A2 (zh
Inventor
陈永奇
白仲虎
丁玉龙
Original Assignee
陈永奇
白仲虎
丁玉龙
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Application filed by 陈永奇, 白仲虎, 丁玉龙 filed Critical 陈永奇
Publication of WO2015027847A2 publication Critical patent/WO2015027847A2/zh
Publication of WO2015027847A3 publication Critical patent/WO2015027847A3/zh

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

一种含奥司他韦羧酸胍基类似体和/或其乙酯的制剂通过吸入进行给药的方法。所述方法可以治疗流行性感冒病毒引起的感冒,是一种药物剂量小,副作用少,起效快的方法。所述给药通过干粉、喷粉器、定量剂量吸入器或雾化器中的一种或两种以上方式进行。
PCT/CN2014/084835 2013-08-26 2014-08-20 含有奥司他韦羧酸胍基类似体和/或其乙酯制剂的给药方法 WO2015027847A2 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201310376245.X 2013-08-26
CN201310376245XA CN103446078A (zh) 2013-08-26 2013-08-26 含有奥司他韦羧酸胍基类似体和/或其乙酯制剂的给药方法

Publications (2)

Publication Number Publication Date
WO2015027847A2 WO2015027847A2 (zh) 2015-03-05
WO2015027847A3 true WO2015027847A3 (zh) 2015-04-23

Family

ID=49729200

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2014/084835 WO2015027847A2 (zh) 2013-08-26 2014-08-20 含有奥司他韦羧酸胍基类似体和/或其乙酯制剂的给药方法

Country Status (2)

Country Link
CN (1) CN103446078A (zh)
WO (1) WO2015027847A2 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2592376A (en) * 2020-02-25 2021-09-01 Aer Beatha Ltd Canister

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009143011A1 (en) * 2008-05-20 2009-11-26 Novartis Ag Antiviral compositions, methods of making and using such compositions, and systems for pulmonary delivery of such compositions
WO2011035128A1 (en) * 2009-09-17 2011-03-24 Mutual Pharmaceutical Company, Inc. Method of treating asthma with antiviral agents

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009143011A1 (en) * 2008-05-20 2009-11-26 Novartis Ag Antiviral compositions, methods of making and using such compositions, and systems for pulmonary delivery of such compositions
WO2011035128A1 (en) * 2009-09-17 2011-03-24 Mutual Pharmaceutical Company, Inc. Method of treating asthma with antiviral agents

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
LI, WEIXING ET AL.: "Identification of GS 4104 as an Orally Bioavailable Prodrug of the Influenza Virus Neuraminidase Inhibitor GS 4071", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY., vol. 42, no. 3, 31 March 1998 (1998-03-31) *

Also Published As

Publication number Publication date
CN103446078A (zh) 2013-12-18
WO2015027847A2 (zh) 2015-03-05

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