MX2016007182A - Inhalador de polvo seco. - Google Patents

Inhalador de polvo seco.

Info

Publication number
MX2016007182A
MX2016007182A MX2016007182A MX2016007182A MX2016007182A MX 2016007182 A MX2016007182 A MX 2016007182A MX 2016007182 A MX2016007182 A MX 2016007182A MX 2016007182 A MX2016007182 A MX 2016007182A MX 2016007182 A MX2016007182 A MX 2016007182A
Authority
MX
Mexico
Prior art keywords
dry powder
medicament
powder inhaler
reservoir
budesonide
Prior art date
Application number
MX2016007182A
Other languages
English (en)
Inventor
Arp Jan
Imre Goller Michael
Keegstra Johan
Original Assignee
Pharmachemie Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmachemie Bv filed Critical Pharmachemie Bv
Publication of MX2016007182A publication Critical patent/MX2016007182A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
    • A61M15/0008—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Otolaryngology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Esta invención proporciona un inhalador de polvo seco de budesonida/formoterol que comprende: un depósito que contiene un medicamento de polvo seco y una disposición para suministrar una dosis medida del medicamento desde el depósito; un desaglomerador ciclónico para disgregar aglomerados del medicamento de polvo seco; un pasaje de suministro para dirigir un flujo de aire de inhalación inducida a través de una boquilla, el pasaje de suministro que se extiende a la dosis medida del medicamento, en donde el medicamento comprende fumarato de formoterol micronizado, budesonida micronizada y un portador de lactosa, el portador de lactosa tiene una distribución de tamaño de partícula d10 = 20-65 µm, d50 = 80-120 µm, d90 = 130-180 µm y <10 µm = <10%.
MX2016007182A 2013-12-09 2014-11-19 Inhalador de polvo seco. MX2016007182A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1321712.0A GB201321712D0 (en) 2013-12-09 2013-12-09 Dry Powder Inhaler
PCT/EP2014/075043 WO2015086276A1 (en) 2013-12-09 2014-11-19 Dry powder inhaler

Publications (1)

Publication Number Publication Date
MX2016007182A true MX2016007182A (es) 2016-10-26

Family

ID=50000399

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016007182A MX2016007182A (es) 2013-12-09 2014-11-19 Inhalador de polvo seco.

Country Status (21)

Country Link
US (2) US11020546B2 (es)
EP (2) EP3398638B1 (es)
JP (2) JP6450388B2 (es)
KR (2) KR102460197B1 (es)
CN (2) CN105813675B (es)
AR (1) AR098640A1 (es)
AU (2) AU2014361085B2 (es)
BR (1) BR112016011996B1 (es)
CA (1) CA2931165A1 (es)
DK (2) DK3398638T3 (es)
EA (1) EA034245B1 (es)
ES (2) ES2871820T3 (es)
GB (1) GB201321712D0 (es)
HU (2) HUE039641T2 (es)
IL (2) IL246044B (es)
MX (1) MX2016007182A (es)
PL (2) PL3079744T3 (es)
PT (1) PT3398638T (es)
TR (1) TR201810066T4 (es)
TW (1) TWI592180B (es)
WO (1) WO2015086276A1 (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201321712D0 (en) 2013-12-09 2014-01-22 Pharmachemie Bv Dry Powder Inhaler
GB201321717D0 (en) * 2013-12-09 2014-01-22 Pharmachemie Bv Inhalable Medicaments
WO2016089981A1 (en) * 2014-12-04 2016-06-09 Carefusion 2200, Inc. Breath-actuated nebulizer for medicine inhalation
USD832998S1 (en) * 2016-10-21 2018-11-06 Norton (Waterford) Limited Inhaler
USD832997S1 (en) * 2016-10-21 2018-11-06 Norton (Waterford) Limited Inhaler
USD852947S1 (en) * 2016-10-21 2019-07-02 Norton (Waterford) Limited Inhaler
ES2884802T3 (es) 2016-11-18 2021-12-13 Norton Waterford Ltd Dispositivo de administración de fármacos con componentes electrónicos
EP3733233A1 (en) * 2016-11-18 2020-11-04 Norton (Waterford) Limited Inhaler
USD853555S1 (en) * 2017-01-03 2019-07-09 Norton (Waterford) Limited Inhaler
CN107737393B (zh) * 2017-10-12 2020-08-28 上海新黄河制药有限公司 一种用于粉雾剂吸入装置的制剂雾化流道
CN107715264B (zh) * 2017-10-12 2021-01-29 上海新黄河制药有限公司 一种粉雾剂装置制剂粉末团聚物的分散/解聚装置
CN110201281B (zh) * 2018-02-28 2021-08-06 张江 吸入给药装置和吸入给药组合结构
USD960349S1 (en) 2019-02-04 2022-08-09 Orion Corporation Inhaler
US11554226B2 (en) * 2019-05-17 2023-01-17 Norton (Waterford) Limited Drug delivery device with electronics
USD949324S1 (en) * 2019-07-26 2022-04-19 Lupin Ltd. Inhaler
USD948704S1 (en) * 2019-07-26 2022-04-12 Lupin Ltd. Inhaler
USD948703S1 (en) * 2019-07-26 2022-04-12 Lupin Ltd. Inhaler
USD949323S1 (en) * 2019-07-26 2022-04-19 Lupin Ltd. Inhaler
KR102354664B1 (ko) 2020-01-07 2022-01-24 제이디코스파마 주식회사 약제 흡입기
KR102420393B1 (ko) 2020-05-28 2022-07-13 제이디코스파마 주식회사 약제 기화 흡입기
KR102494694B1 (ko) 2020-11-10 2023-02-01 권오석 약제 기화 흡입기
USD1001996S1 (en) * 2020-12-16 2023-10-17 Alfred Von Schuckmann Inhaler
GB202102026D0 (en) * 2021-02-12 2021-03-31 Cambridge Healthcare Innovations Ltd Medical apparatus and method
US11925749B2 (en) * 2021-03-18 2024-03-12 Funai Electric Co., Ltd. Venting of pharmaceutical drug delivery device for air flow and humidity control
CN114632235B (zh) * 2022-03-04 2023-04-25 华中科技大学 一种干粉吸入器

Family Cites Families (23)

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Publication number Priority date Publication date Assignee Title
US5874063A (en) * 1991-04-11 1999-02-23 Astra Aktiebolag Pharmaceutical formulation
PT613371E (pt) 1991-12-18 2002-07-31 Astrazeneca Ab Nova combinacao de formoterol e budesonido
SE9703407D0 (sv) 1997-09-19 1997-09-19 Astra Ab New use
CA2347856C (en) * 1998-11-13 2009-02-17 Jago Research Ag Dry powder for inhalation
PE20020067A1 (es) 2000-06-23 2002-02-05 Norton Healthcare Ltd Desaglomerador para inhalador de polvo seco accionado por la respiracion
PE20020074A1 (es) 2000-06-23 2002-02-05 Norton Healthcare Ltd Sistema dosificador para inhalador de medicamento
SE0200312D0 (sv) 2002-02-01 2002-02-01 Astrazeneca Ab Novel composition
ITMI20051999A1 (it) * 2005-10-21 2007-04-22 Eratech S R L Formulazioni inalatorie di farmaci in fora di polvere secca per somministrazione come tale o con nebulizzatore e dotate di elevata erogabilita' respirabilita' e stabilita'
GB0602897D0 (en) 2006-02-13 2006-03-22 Jagotec Ag Improvements In Or Relating To Dry Powder Inhaler Devices
CN101422436B (zh) * 2007-10-31 2010-12-01 江苏正大天晴药业股份有限公司 供吸入干粉组合物
US9956170B2 (en) * 2008-06-26 2018-05-01 3M Innovative Properties Company Dry powder pharmaceutical compositions for pulmonary administration, and methods of manufacturing thereof
US20100291221A1 (en) 2009-05-15 2010-11-18 Robert Owen Cook Method of administering dose-sparing amounts of formoterol fumarate-budesonide combination particles by inhalation
GB0918150D0 (en) * 2009-10-16 2009-12-02 Jagotec Ag Improved formulations
TR200907914A2 (tr) * 2009-10-20 2011-05-23 Bi̇lgi̇ç Mahmut Kortlkosteroid içeren kuru toz formunda farmasötik bileşim.
GB0919465D0 (en) 2009-11-06 2009-12-23 Norton Healthcare Ltd Airflow adaptor for a breath-actuated dry powder inhaler
TR201000680A2 (tr) * 2010-01-29 2011-08-22 B�Lg�� Mahmut Tiotropyum, formoterol ve budesonid içeren farmasötik bileşimler
US9259376B2 (en) * 2010-06-03 2016-02-16 Sima Patent Ve Lisanslama Hizmetleri Ltd. Sti. Process for dry powder formulations
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JOP20120023B1 (ar) * 2011-02-04 2022-03-14 Novartis Ag صياغات مساحيق جافة من جسيمات تحتوي على واحد أو اثنين من المواد الفعالة لعلاج امراض ممرات الهواء الانسدادية او الالتهابية
DE102011085154A1 (de) 2011-10-25 2013-04-25 Evonik Industries Ag Vorrichtung zur Vermeidung von Ablagerungen an optischen Komponenten im Laser-Sintern
GB201205632D0 (en) * 2012-03-30 2012-05-16 Vectura Ltd Method and apparatus
GB201319265D0 (en) * 2013-10-31 2013-12-18 Norton Waterford Ltd Medicament inhaler
GB201321712D0 (en) 2013-12-09 2014-01-22 Pharmachemie Bv Dry Powder Inhaler

Also Published As

Publication number Publication date
BR112016011996B1 (pt) 2023-01-10
CN105813675A (zh) 2016-07-27
KR20210108500A (ko) 2021-09-02
CN110812634A (zh) 2020-02-21
AU2018226472A1 (en) 2018-09-27
JP6450388B2 (ja) 2019-01-09
ES2871820T3 (es) 2021-11-02
TWI592180B (zh) 2017-07-21
IL246044B (en) 2020-02-27
JP2017500105A (ja) 2017-01-05
AR098640A1 (es) 2016-06-01
DK3079744T3 (en) 2018-08-06
EP3398638A1 (en) 2018-11-07
EP3079744A1 (en) 2016-10-19
WO2015086276A1 (en) 2015-06-18
EP3398638B1 (en) 2021-04-28
AU2014361085B2 (en) 2018-06-14
CA2931165A1 (en) 2015-06-18
EP3079744B1 (en) 2018-07-04
CN110812634B (zh) 2022-06-03
HUE039641T2 (hu) 2019-01-28
JP2019055257A (ja) 2019-04-11
AU2014361085A1 (en) 2016-07-07
US20210353881A1 (en) 2021-11-18
AU2018226472B2 (en) 2020-03-19
TR201810066T4 (tr) 2018-08-27
IL272629A (en) 2020-03-31
PT3398638T (pt) 2021-06-01
US11642475B2 (en) 2023-05-09
IL246044A0 (en) 2016-07-31
CN105813675B (zh) 2019-12-13
NZ721308A (en) 2022-03-25
KR102460197B1 (ko) 2022-10-28
EA034245B1 (ru) 2020-01-21
GB201321712D0 (en) 2014-01-22
JP6907178B2 (ja) 2021-07-21
DK3398638T3 (da) 2021-05-25
PL3079744T3 (pl) 2018-12-31
KR102296835B1 (ko) 2021-09-02
TW201531313A (zh) 2015-08-16
HUE055451T2 (hu) 2021-11-29
BR112016011996A2 (pt) 2018-05-22
KR20160105800A (ko) 2016-09-07
US11020546B2 (en) 2021-06-01
ES2679523T3 (es) 2018-08-28
EA201590738A1 (ru) 2015-09-30
IL272629B (en) 2021-12-01
US20160303336A1 (en) 2016-10-20
PL3398638T3 (pl) 2021-08-30

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