EA201492153A1 - Смесь для ингибирования биосинтеза меланина - Google Patents
Смесь для ингибирования биосинтеза меланинаInfo
- Publication number
- EA201492153A1 EA201492153A1 EA201492153A EA201492153A EA201492153A1 EA 201492153 A1 EA201492153 A1 EA 201492153A1 EA 201492153 A EA201492153 A EA 201492153A EA 201492153 A EA201492153 A EA 201492153A EA 201492153 A1 EA201492153 A1 EA 201492153A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- skin
- mixture
- melanin biosynthesis
- counteract
- cosmetic
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 230000008099 melanin synthesis Effects 0.000 title abstract 2
- 230000005764 inhibitory process Effects 0.000 title 1
- 206010008570 Chloasma Diseases 0.000 abstract 2
- 208000003351 Melanosis Diseases 0.000 abstract 2
- 239000002537 cosmetic Substances 0.000 abstract 2
- PQSXNIMHIHYFEE-UHFFFAOYSA-N 4-(1-phenylethyl)benzene-1,3-diol Chemical compound C=1C=C(O)C=C(O)C=1C(C)C1=CC=CC=C1 PQSXNIMHIHYFEE-UHFFFAOYSA-N 0.000 abstract 1
- DUKURNFHYQXCJG-UHFFFAOYSA-N Lewis A pentasaccharide Natural products OC1C(O)C(O)C(C)OC1OC1C(OC2C(C(O)C(O)C(CO)O2)O)C(NC(C)=O)C(OC2C(C(OC3C(OC(O)C(O)C3O)CO)OC(CO)C2O)O)OC1CO DUKURNFHYQXCJG-UHFFFAOYSA-N 0.000 abstract 1
- OVRNDRQMDRJTHS-FMDGEEDCSA-N N-acetyl-beta-D-glucosamine Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O OVRNDRQMDRJTHS-FMDGEEDCSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 206010024217 lentigo Diseases 0.000 abstract 1
- 229950006780 n-acetylglucosamine Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000009759 skin aging Effects 0.000 abstract 1
- 231100000444 skin lesion Toxicity 0.000 abstract 1
- 206010040882 skin lesion Diseases 0.000 abstract 1
- 230000037303 wrinkles Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A61K31/231—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/18—Antioxidants, e.g. antiradicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Настоящее изобретение относится к смеси, содержащей ацетилглюкозамин и 4-(1-фенилэтил)-1,3-бензолдиол, для применения в качестве косметического и/или лекарственного средства, и в частности для ингибирования биосинтеза меланина, и к косметической и/или фармацевтической композиции, содержащей такую смесь, для лечения гиперпигментированных поражений кожи, таких как, например, солнечное лентиго, возрастные пятна, мелазма и хлоазма, но не ограничивающихся ими, для придания однородного цвета коже, для противодействия образованию свободных радикалов и для противодействия или предупреждения признаков старения кожи, таких как морщины и утрата тона кожи, и для улучшения общего эстетического состояния кожи.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000092A ITBS20120092A1 (it) | 2012-06-04 | 2012-06-04 | Miscela per l'inibizione della biosintesi della melanina |
PCT/IB2013/054606 WO2013182996A1 (en) | 2012-06-04 | 2013-06-04 | Mixture for the inhibition of melanin biosynthesis |
Publications (2)
Publication Number | Publication Date |
---|---|
EA201492153A1 true EA201492153A1 (ru) | 2015-05-29 |
EA030102B1 EA030102B1 (ru) | 2018-06-29 |
Family
ID=46758827
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201492153A EA030102B1 (ru) | 2012-06-04 | 2013-06-04 | Смесь для ингибирования биосинтеза меланина |
Country Status (14)
Country | Link |
---|---|
US (1) | US20150110725A1 (ru) |
EP (1) | EP2854783B1 (ru) |
JP (1) | JP2015518877A (ru) |
KR (1) | KR20150023544A (ru) |
CN (1) | CN104507462A (ru) |
EA (1) | EA030102B1 (ru) |
ES (1) | ES2668848T3 (ru) |
IN (1) | IN2014MN02468A (ru) |
IT (1) | ITBS20120092A1 (ru) |
MY (1) | MY169101A (ru) |
PL (1) | PL2854783T3 (ru) |
SG (2) | SG11201408053TA (ru) |
TR (1) | TR201806726T4 (ru) |
WO (1) | WO2013182996A1 (ru) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109789066A (zh) * | 2016-06-30 | 2019-05-21 | 西姆莱斯股份公司 | 含有间苯二酚衍生物的药物和化妆组合物 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002053448A (ja) * | 2000-07-28 | 2002-02-19 | Pentapharm Ltd | アウトドア化粧料 |
DE10324566A1 (de) * | 2003-05-30 | 2004-12-16 | Symrise Gmbh & Co. Kg | Verwendung von Diphenylmethan-Derivaten als Tyrosinase-Inhibitoren |
CN101365414A (zh) | 2006-01-05 | 2009-02-11 | 西姆莱斯有限责任两合公司 | 包含酚类化合物和二苯甲酮的稳定化制剂 |
CN101139288B (zh) * | 2006-09-07 | 2011-06-15 | 黑龙江大学 | 复合型固体超强酸催化制备亚油酸乙酯的方法 |
US20110171288A1 (en) * | 2008-02-20 | 2011-07-14 | Fatemeh Mohammadi | Topical compositions and methods for whitening skin |
FR2939669B1 (fr) * | 2008-12-17 | 2011-03-25 | Oreal | Procede cosmetique pour controler le brunissement de la peau induit par les radiations uv ; compositions. |
CA3043905A1 (en) * | 2011-01-07 | 2012-07-12 | Allergan, Inc. | Compositions comprising substituted benzaldehydes and use thereof for lightening skin or treating hyperpigmenation and hypermelanosis disorders |
-
2012
- 2012-06-04 IT IT000092A patent/ITBS20120092A1/it unknown
-
2013
- 2013-06-04 ES ES13739805.3T patent/ES2668848T3/es active Active
- 2013-06-04 TR TR2018/06726T patent/TR201806726T4/tr unknown
- 2013-06-04 PL PL13739805T patent/PL2854783T3/pl unknown
- 2013-06-04 JP JP2015515632A patent/JP2015518877A/ja active Pending
- 2013-06-04 EP EP13739805.3A patent/EP2854783B1/en active Active
- 2013-06-04 US US14/405,371 patent/US20150110725A1/en not_active Abandoned
- 2013-06-04 EA EA201492153A patent/EA030102B1/ru not_active IP Right Cessation
- 2013-06-04 SG SG11201408053TA patent/SG11201408053TA/en unknown
- 2013-06-04 CN CN201380040108.7A patent/CN104507462A/zh active Pending
- 2013-06-04 KR KR20147036941A patent/KR20150023544A/ko not_active Application Discontinuation
- 2013-06-04 WO PCT/IB2013/054606 patent/WO2013182996A1/en active Application Filing
- 2013-06-04 SG SG10201704303VA patent/SG10201704303VA/en unknown
- 2013-06-04 MY MYPI2014703654A patent/MY169101A/en unknown
-
2014
- 2014-12-04 IN IN2468MUN2014 patent/IN2014MN02468A/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP2015518877A (ja) | 2015-07-06 |
PL2854783T3 (pl) | 2018-08-31 |
IN2014MN02468A (ru) | 2015-07-10 |
US20150110725A1 (en) | 2015-04-23 |
SG11201408053TA (en) | 2015-01-29 |
EP2854783B1 (en) | 2018-02-14 |
MY169101A (en) | 2019-02-18 |
EP2854783A1 (en) | 2015-04-08 |
KR20150023544A (ko) | 2015-03-05 |
ITBS20120092A1 (it) | 2013-12-05 |
TR201806726T4 (tr) | 2018-06-21 |
WO2013182996A1 (en) | 2013-12-12 |
EA030102B1 (ru) | 2018-06-29 |
CN104507462A (zh) | 2015-04-08 |
SG10201704303VA (en) | 2017-07-28 |
ES2668848T3 (es) | 2018-05-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2902938C (en) | Peptides for skin rejuvenation and methods of using the same | |
MX2020010535A (es) | Inhibidor de ezh2 para usarse en el tratamiento de sarcoma epiteloide. | |
PH12015500825B1 (en) | Substituted benzene compounds | |
TNSN08381A1 (en) | Cosmetic active ingredient composed of arginine ferrulate and a microalgae and extract its uses | |
MX344530B (es) | Compuestos de benceno substituido. | |
WO2012037155A3 (en) | Tyrosine kinase inhibitors | |
WO2012108689A3 (ko) | 피부미백, 항산화 및 ppar 활성을 갖는 신규 화합물 및 이의 의학적 용도 | |
PH12014501639A1 (en) | Pharmaceutical compositions and methods | |
WO2012099449A3 (ko) | 플라본계 화합물의 신규한 용도 | |
WO2012108677A3 (ko) | 피부미백, 항산화 및 ppar 활성을 갖는 신규 화합물 및 이의 의학적 용도 | |
WO2012076109A3 (de) | 2-pyrone | |
BR112013002215A2 (pt) | uso de feijões de café verde para regulagem de distúrbios de pigmentação da pele | |
MX358727B (es) | Composicion cosmetica dermatologica que comprende una merocianina y una fase aceitosa que comprende al menos un compuesto amido especifico. | |
EA201170672A1 (ru) | Соединения, пригодные для лечения целлюлита | |
WO2015081306A3 (en) | Peptide tyrosinase activators | |
MX2014003449A (es) | Heterociclocarbonilaminotiazoles, preparaciones cosmeticas o dermatologicas que contienen los mismos y su uso para el control y la profilaxis de pigmentacion indeseada de la piel. | |
WO2009112653A3 (fr) | Composition cosmétique et/ou dermatologique | |
MX2015009054A (es) | Composicion cosmetica o dermatologica que comprende una merocianina, una fase aceitosa y un monoalcanol c1-c4. | |
EA201791493A1 (ru) | Композиция для отбеливания кожи, содержащая ниацинамид и иломастат | |
EA201492153A1 (ru) | Смесь для ингибирования биосинтеза меланина | |
TN2011000554A1 (en) | Use of delta-tocopheryl-carbohydrate as a depigmenting agent | |
MX2009012712A (es) | Nuevas 4-fenil-imidazol-2-tionas como inhibidores de la tirosinasa, su procedimiento de preparacion y su uso en medicina humana asi como en cosmetica. | |
MX2009012714A (es) | Nuevas 4-heteroail-imidazol-2-tionas como inhibidores de la tirosinasa, su procedimiento de preparacion y su uso en medicina humana asi como en cosmetica. | |
EA201100392A1 (ru) | Интерлейкин-1 бета в косметических композициях и способы его использования | |
WO2019078662A3 (ko) | 데스모디움 스컥스 용매 추출물 또는 이의 분획물의 티로시나아제 저해 및 미백활성 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC1A | Registration of transfer to a eurasian application by force of assignment | ||
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG TJ TM |