WO2012108677A3 - 피부미백, 항산화 및 ｐｐａｒ 활성을 갖는 신규 화합물 및 이의 의학적 용도 - Google Patents

피부미백, 항산화 및 ｐｐａｒ 활성을 갖는 신규 화합물 및 이의 의학적 용도 Download PDF

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WO2012108677A3
WO2012108677A3 PCT/KR2012/000899 KR2012000899W WO2012108677A3 WO 2012108677 A3 WO2012108677 A3 WO 2012108677A3 KR 2012000899 W KR2012000899 W KR 2012000899W WO 2012108677 A3 WO2012108677 A3 WO 2012108677A3
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skin
whitening
oxidizing
activity
medical use
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PCT/KR2012/000899
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French (fr)
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WO2012108677A2 (ko
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정해영
문형룡
박민희
하영미
박윤정
박지영
김진아
이지연
이경진
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부산대학교 산학협력단
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Priority to US13/984,573 priority Critical patent/US9216148B2/en
Priority to JP2013553354A priority patent/JP6000981B2/ja
Publication of WO2012108677A2 publication Critical patent/WO2012108677A2/ko
Publication of WO2012108677A3 publication Critical patent/WO2012108677A3/ko
Priority to US14/973,752 priority patent/US9896421B2/en

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Abstract

본 발명은 피부미백, 항산화 및 PPAR 활성을 갖는 신규 화합물 및 이의 의학적 용도에 관한 것으로, 본 발명에 따른 화합물들은 티로시나아제를 억제하는 피부미백 활성을 지니므로 피부미백용 약학조성물 또는 화장품에 유용하게 사용될 수 있고, 항산화 활성을 지니므로 피부노화 등의 예방 또는 치료에 유용하게 사용될 수 있으며, 또한 PPAR 활성 특히, PPARα 및 PPARγ 활성을 지니므로 비만, 대사성 질환 또는 심혈관계 질환을 예방하고 치료하는 데에 유용한 약학조성물 또는 건강식품으로 사용될 수 있다.
PCT/KR2012/000899 2011-02-09 2012-02-08 피부미백, 항산화 및 ｐｐａｒ 활성을 갖는 신규 화합물 및 이의 의학적 용도 WO2012108677A2 (ko)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US13/984,573 US9216148B2 (en) 2011-02-09 2012-02-08 Compound having skin-whitening, anti-oxidizing and PPAR activities and medical use therefor
JP2013553354A JP6000981B2 (ja) 2011-02-09 2012-02-08 皮膚美白、抗酸化及びｐｐａｒ活性を有する新規化合物及びその医学的用途
US14/973,752 US9896421B2 (en) 2011-02-09 2015-12-18 Compound having skin-whitening, anti-oxidizing and PPAR activities and medical use thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2011-0011543 2011-02-09
KR1020110011543A KR101411838B1 (ko) 2011-02-09 2011-02-09 피부미백, 항산화 및 ｐｐａｒ 활성을 갖는 신규 화합물 및 이의 의학적 용도

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US13/984,573 A-371-Of-International US9216148B2 (en) 2011-02-09 2012-02-08 Compound having skin-whitening, anti-oxidizing and PPAR activities and medical use therefor
US14/973,752 Continuation US9896421B2 (en) 2011-02-09 2015-12-18 Compound having skin-whitening, anti-oxidizing and PPAR activities and medical use thereof

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WO2012108677A2 WO2012108677A2 (ko) 2012-08-16
WO2012108677A3 true WO2012108677A3 (ko) 2012-11-01

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US (2) US9216148B2 (ko)
JP (1) JP6000981B2 (ko)
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WO (1) WO2012108677A2 (ko)

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CN104983731B (zh) * 2015-07-27 2018-01-19 苏州大学 (z)‑2‑亚氨基‑5‑(3,5‑二甲氧基苯甲撑基)‑1‑甲基咪唑烷‑4‑酮在制备心血管药物中的应用
KR101817287B1 (ko) 2016-01-08 2018-01-10 조선대학교 산학협력단 티아졸리딘디온 유도체 및 그의 용도
GB201601142D0 (en) * 2016-01-21 2016-03-09 Oxehealth Ltd Method and apparatus for estimating breathing rate
KR101699659B1 (ko) * 2016-01-26 2017-01-24 부산대학교 산학협력단 (ｚ)―５―(４―히드록시―３，５―디메톡시벤질리덴)―２―티옥소이미다졸리딘―４―온)을 유효성분으로 포함하는 암 예방 또는 치료용 조성물
DE102016011954A1 (de) 2016-10-07 2018-04-12 Merck Patent Gmbh Barbitursäurederivate als Selbstbräunungssubstanzen
FR3063903B1 (fr) * 2017-03-20 2019-04-12 Universite Paris Diderot Nouveaux composes, compositions et methodes pour le traitement de la resistance a l’insuline
KR102131998B1 (ko) * 2018-11-05 2020-07-08 부산대학교 산학협력단 티아졸리딘디온 유도체를 유효성분으로 포함하는 간 질환 예방 또는 치료용 조성물
KR102188791B1 (ko) * 2019-10-25 2020-12-09 서울대학교 산학협력단 피부 미백용 조성물 및 이의 용도
DE102019129221B4 (de) * 2019-10-29 2022-05-12 Chiracon Gmbh Verfahren zur Synthese von DOPA mit einer fotolabilen Schutzgruppe und Zwischenprodukten zu dessen Herstellung

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JP6000981B2 (ja) 2016-10-05
US9896421B2 (en) 2018-02-20
US20160102065A1 (en) 2016-04-14
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