EA201491845A1 - Получение стерильных активных фармацевтических ингредиентов - Google Patents

Получение стерильных активных фармацевтических ингредиентов

Info

Publication number
EA201491845A1
EA201491845A1 EA201491845A EA201491845A EA201491845A1 EA 201491845 A1 EA201491845 A1 EA 201491845A1 EA 201491845 A EA201491845 A EA 201491845A EA 201491845 A EA201491845 A EA 201491845A EA 201491845 A1 EA201491845 A1 EA 201491845A1
Authority
EA
Eurasian Patent Office
Prior art keywords
active pharmaceutical
pharmaceutical ingredients
sterile active
obtaining sterile
obtaining
Prior art date
Application number
EA201491845A
Other languages
English (en)
Other versions
EA028596B1 (ru
Inventor
Марио Леоне
Пьерфранческо Морозини
Original Assignee
Икром Спа
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Икром Спа filed Critical Икром Спа
Publication of EA201491845A1 publication Critical patent/EA201491845A1/ru
Publication of EA028596B1 publication Critical patent/EA028596B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029—Radiation
    • A61L2/0035—Gamma radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08—Radiation
    • A61L2/081—Gamma radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20—Targets to be treated
    • A61L2202/21—Pharmaceuticals, e.g. medicaments, artificial body parts

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Изобретение относится к способу получения стерильных активных фармацевтических ингредиентов (АФИ), полезных в приготовлении стерильного вещества для офтальмологического применения. Способ включает стерилизационную обработку гамма-лучами порошка АФИ в защитной газовой среде.
EA201491845A 2012-05-09 2012-05-09 Получение стерильных активных фармацевтических ингредиентов EA028596B1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IT2012/000136 WO2013168186A1 (en) 2012-05-09 2012-05-09 Production of sterile active pharmaceutical ingredients

Publications (2)

Publication Number Publication Date
EA201491845A1 true EA201491845A1 (ru) 2015-02-27
EA028596B1 EA028596B1 (ru) 2017-12-29

Family

ID=46321406

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201491845A EA028596B1 (ru) 2012-05-09 2012-05-09 Получение стерильных активных фармацевтических ингредиентов

Country Status (16)

Country Link
US (1) US10953115B2 (ru)
EP (1) EP2846845B1 (ru)
JP (1) JP6122485B2 (ru)
KR (1) KR101966830B1 (ru)
CN (1) CN104487099B (ru)
BR (1) BR112014027885B1 (ru)
CA (1) CA2872336C (ru)
EA (1) EA028596B1 (ru)
ES (1) ES2624250T3 (ru)
HR (1) HRP20170529T1 (ru)
HU (1) HUE034356T2 (ru)
IN (1) IN2014DN09993A (ru)
MX (1) MX349920B (ru)
PL (1) PL2846845T3 (ru)
PT (1) PT2846845T (ru)
WO (1) WO2013168186A1 (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210145836A1 (en) * 2012-05-09 2021-05-20 Icrom Spa Production of sterile active pharmaceutical ingredients
PT3411004T (pt) * 2016-02-05 2021-05-11 Innopharma Inc Processo de fabrico de um saco de perfusão estável e pronto para utilização para uma formulação sensível à oxidação
BE1024110B1 (fr) * 2016-10-18 2017-11-16 Auxin Surgery Sa Dispositif, procédé et formulation pour dissection assistée de manière chimique
AU2017233581B2 (en) * 2016-03-14 2022-08-04 Auxin Surgery Sa Device, method and formulation for chemically assisted dissection
DE102017107124A1 (de) * 2017-04-03 2018-10-04 Ferton Holding S.A. Pulver zur Reinigung eines inneren Körperteils und/oder eines Implantats, Verfahren zur Herstellung eines solchen Pulvers und geeignete Verwendungen
IT202100006794A1 (it) 2021-03-22 2022-09-22 Icrom Srl Processo per preparare il verde indocianina

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2004553B1 (de) 1970-02-02 1971-05-19 Fa B Braun, 3508 Melsungen Verfahren zur Herstellung von Leit schienen aus menschlichen oder tierischen Geweben zur Wiederherstellung beschädigter oder zerstörter spezifischer Gewebsteile im menschlichen und tierischen Korper
US6071904A (en) * 1996-12-11 2000-06-06 Alcon Laboratories, Inc. Process for manufacturing ophthalmic suspensions
US20030095890A1 (en) 2001-09-24 2003-05-22 Shirley Miekka Methods for sterilizing biological materials containing non-aqueous solvents
MX2007014480A (es) * 2005-05-19 2008-04-22 Albiorex Llc Esterilizacion terminal de productos de colageno inyectables.
MX2008014283A (es) 2006-05-09 2008-11-18 Astrazeneca Ab Formulacion parental la cual comprende un inhibidor de bomba de protones esterilizado en su recipiente final por radiacion de ionizacion.
CN107007581A (zh) * 2006-08-24 2017-08-04 田纳西大学研究基金会 取代的n‑酰基苯胺及其使用方法
GB0626021D0 (en) 2006-12-29 2007-02-07 Insense Ltd The stabilisation of proteins
CA2697160A1 (en) * 2007-08-21 2009-02-26 Harbor Biosciences, Inc. Stabilized therapeutic compositions and formulations
EP2394637A1 (en) * 2010-05-21 2011-12-14 Zaklady Farmaceutyczne Polpharma SA Process for obtaining sterile brinzolamide suspensions

Also Published As

Publication number Publication date
BR112014027885A2 (pt) 2017-06-27
KR101966830B1 (ko) 2019-04-08
US10953115B2 (en) 2021-03-23
KR20150024821A (ko) 2015-03-09
EP2846845B1 (en) 2017-03-01
PT2846845T (pt) 2017-06-02
CA2872336C (en) 2019-08-13
CN104487099A (zh) 2015-04-01
ES2624250T3 (es) 2017-07-13
CA2872336A1 (en) 2013-11-14
BR112014027885B1 (pt) 2022-07-26
EA028596B1 (ru) 2017-12-29
JP6122485B2 (ja) 2017-04-26
EP2846845A1 (en) 2015-03-18
WO2013168186A1 (en) 2013-11-14
MX2014013238A (es) 2015-04-08
US20150141412A1 (en) 2015-05-21
HRP20170529T1 (hr) 2017-06-16
MX349920B (es) 2017-08-21
HUE034356T2 (en) 2018-02-28
PL2846845T3 (pl) 2017-07-31
CN104487099B (zh) 2017-06-20
IN2014DN09993A (ru) 2015-08-14
JP2015523327A (ja) 2015-08-13

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