EA201490519A1 - Селективные модуляторы рецепторов андрогенов - Google Patents
Селективные модуляторы рецепторов андрогеновInfo
- Publication number
- EA201490519A1 EA201490519A1 EA201490519A EA201490519A EA201490519A1 EA 201490519 A1 EA201490519 A1 EA 201490519A1 EA 201490519 A EA201490519 A EA 201490519A EA 201490519 A EA201490519 A EA 201490519A EA 201490519 A1 EA201490519 A1 EA 201490519A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- androgen receptors
- selective modulators
- modulators
- selective
- androgen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/06—Anabolic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/22—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/14—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161546711P | 2011-10-13 | 2011-10-13 | |
| PCT/US2012/058824 WO2013055577A1 (en) | 2011-10-13 | 2012-10-05 | Selective androgen receptor modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201490519A1 true EA201490519A1 (ru) | 2014-09-30 |
Family
ID=47046879
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201490519A EA201490519A1 (ru) | 2011-10-13 | 2012-10-05 | Селективные модуляторы рецепторов андрогенов |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US8658693B2 (OSRAM) |
| EP (1) | EP2766350B1 (OSRAM) |
| JP (1) | JP6002228B2 (OSRAM) |
| KR (1) | KR20140067102A (OSRAM) |
| CN (1) | CN103842348B (OSRAM) |
| AP (1) | AP2014007548A0 (OSRAM) |
| AR (1) | AR088082A1 (OSRAM) |
| AU (1) | AU2012321113B2 (OSRAM) |
| BR (1) | BR112014008668A2 (OSRAM) |
| CA (1) | CA2847889A1 (OSRAM) |
| CL (1) | CL2014000895A1 (OSRAM) |
| CO (1) | CO6910195A2 (OSRAM) |
| CR (1) | CR20140156A (OSRAM) |
| DO (1) | DOP2014000075A (OSRAM) |
| EA (1) | EA201490519A1 (OSRAM) |
| EC (1) | ECSP14013305A (OSRAM) |
| ES (1) | ES2626820T3 (OSRAM) |
| GT (1) | GT201400067A (OSRAM) |
| IL (1) | IL231440A0 (OSRAM) |
| MX (1) | MX2014004558A (OSRAM) |
| PE (1) | PE20141669A1 (OSRAM) |
| PH (1) | PH12014500808A1 (OSRAM) |
| PL (1) | PL2766350T3 (OSRAM) |
| PT (1) | PT2766350T (OSRAM) |
| SG (1) | SG11201401794YA (OSRAM) |
| TN (1) | TN2014000136A1 (OSRAM) |
| TW (1) | TWI449686B (OSRAM) |
| WO (1) | WO2013055577A1 (OSRAM) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140045856A1 (en) | 2012-07-31 | 2014-02-13 | Boehringer Ingelheim International Gmbh | 4-Methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalenes |
| TW201534586A (zh) * | 2013-06-11 | 2015-09-16 | Orion Corp | 新穎ｃｙｐ１７抑制劑／抗雄激素劑 |
| US10093660B2 (en) | 2013-12-04 | 2018-10-09 | Evotec Internatonal Gmbh | Sulfoximine substituted quinazolines for pharmaceutical compositions |
| US9682960B2 (en) | 2013-12-19 | 2017-06-20 | Endorecherche, Inc. | Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety |
| JP6479854B2 (ja) | 2014-05-07 | 2019-03-06 | エヴォテック・インターナショナル・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＥｖｏｔｅｃ Ｉｎｔｅｒｎａｔｉｏｎａｌ ＧｍｂＨ | 医薬組成物のためのスルホキシイミン置換キナゾリン |
| CN114394966B (zh) | 2016-08-15 | 2024-10-11 | 辉瑞公司 | 吡啶并嘧啶酮cdk2/4/6抑制剂 |
| ES2824495T3 (es) | 2016-09-02 | 2021-05-12 | Suven Life Sciences Ltd | Moduladores alostéricos positivos del receptor muscarínico M1 |
| EP3684761A1 (en) | 2017-09-18 | 2020-07-29 | Basf Se | Substituted trifluoromethyloxadiazoles for combating phytopathogenic fungi |
| US11739075B2 (en) * | 2020-06-24 | 2023-08-29 | Celgene Corporation | Cereblon binding compounds, compositions thereof, and methods of treatment therewith |
| WO2025104624A1 (en) * | 2023-11-14 | 2025-05-22 | Pfizer Inc. | Synthesis of 1,5-anhydro-3-({5-chloro-4-[4-fluoro-2-(2-hydroxypropan-2-yl)-1-(propan-2-yl)-1h-benzimidazol-6-yl]pyrimidin-2-yl}amino)-2,3-dideoxy-d-threo-pentitol |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3594405A (en) * | 1968-05-17 | 1971-07-20 | Du Pont | Substituted pyranyl anilines as plant growth modifiers |
| ATE315555T1 (de) * | 2001-05-11 | 2006-02-15 | Pfizer Prod Inc | Thiazolderivate und ihre verwendung als cdk- inhibitoren |
| US8519158B2 (en) * | 2004-03-12 | 2013-08-27 | Ligand Pharmaceuticals Incorporated | Androgen receptor modulator compounds and methods |
| DK1891038T3 (da) * | 2005-05-13 | 2009-01-19 | Lilly Co Eli | Substituerede n-arylpyrrolidiner som selektive androgenreceptormodulatorer |
| ES2384643T3 (es) * | 2005-11-30 | 2012-07-10 | Astellas Pharma Inc. | Derivados de 2-aminobenzamida como inhibidores del receptor vainilloide 1 (VR1) útiles para el tratamiento del dolor o el trastorno de la función de la vejiga |
| CA2684240A1 (en) * | 2007-04-16 | 2008-10-30 | Serenex, Inc. | Tetrahydroindole and tetrahydroindazole derivatives |
| CA2702777A1 (en) * | 2007-10-19 | 2009-04-23 | Michelle Letendre-Hedlund | Methods of identifying environmentally friendly businesses or individuals |
| US8067448B2 (en) * | 2008-02-22 | 2011-11-29 | Radius Health, Inc. | Selective androgen receptor modulators |
-
2012
- 2012-09-27 AR ARP120103597A patent/AR088082A1/es unknown
- 2012-09-28 TW TW101136038A patent/TWI449686B/zh not_active IP Right Cessation
- 2012-10-05 AU AU2012321113A patent/AU2012321113B2/en not_active Ceased
- 2012-10-05 KR KR1020147009338A patent/KR20140067102A/ko not_active Abandoned
- 2012-10-05 PL PL12775406T patent/PL2766350T3/pl unknown
- 2012-10-05 BR BR112014008668A patent/BR112014008668A2/pt not_active IP Right Cessation
- 2012-10-05 PH PH1/2014/500808A patent/PH12014500808A1/en unknown
- 2012-10-05 US US13/645,535 patent/US8658693B2/en active Active
- 2012-10-05 WO PCT/US2012/058824 patent/WO2013055577A1/en not_active Ceased
- 2012-10-05 MX MX2014004558A patent/MX2014004558A/es not_active Application Discontinuation
- 2012-10-05 CA CA2847889A patent/CA2847889A1/en not_active Abandoned
- 2012-10-05 JP JP2014535757A patent/JP6002228B2/ja active Active
- 2012-10-05 SG SG11201401794YA patent/SG11201401794YA/en unknown
- 2012-10-05 EA EA201490519A patent/EA201490519A1/ru unknown
- 2012-10-05 AP AP2014007548A patent/AP2014007548A0/xx unknown
- 2012-10-05 CN CN201280049445.8A patent/CN103842348B/zh active Active
- 2012-10-05 PT PT127754067T patent/PT2766350T/pt unknown
- 2012-10-05 PE PE2014000521A patent/PE20141669A1/es not_active Application Discontinuation
- 2012-10-05 ES ES12775406.7T patent/ES2626820T3/es active Active
- 2012-10-05 EP EP12775406.7A patent/EP2766350B1/en active Active
-
2014
- 2014-03-10 IL IL231440A patent/IL231440A0/en unknown
- 2014-03-17 CO CO14057028A patent/CO6910195A2/es unknown
- 2014-03-28 TN TNP2014000136A patent/TN2014000136A1/en unknown
- 2014-04-04 CR CR20140156A patent/CR20140156A/es unknown
- 2014-04-10 CL CL2014000895A patent/CL2014000895A1/es unknown
- 2014-04-11 DO DO2014000075A patent/DOP2014000075A/es unknown
- 2014-04-11 EC ECSP14013305 patent/ECSP14013305A/es unknown
- 2014-04-11 GT GT201400067A patent/GT201400067A/es unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EA201490519A1 (ru) | Селективные модуляторы рецепторов андрогенов | |
| UA109931C2 (xx) | Піримідинциклогексильні модулятори глюкокортикоїдних рецепторів | |
| CR20140106A (es) | Compuestos y composiciones como inhibidores de la quinasa c-kit | |
| EP2803662A4 (en) | P2X4 Receptor Antagonists | |
| EA201791310A1 (ru) | Химерные антигенные рецепторы к bcma | |
| GT201300196A (es) | Moduladores del receptor de glucagón | |
| EA201690667A1 (ru) | Композиции, содержащие антитело к pdl1 | |
| IL235811A (en) | Pyrazoloquinazulinones and pyrolloquiazoleins are conserved as allosteric modulators of Glutamate receptor II group II | |
| EA201591728A1 (ru) | Гетероциклические соединения и способы их применения | |
| EA201590731A1 (ru) | Антитела к гемагглютинину и способы применения | |
| EA201490037A1 (ru) | Антагонисты trpv4 | |
| EA201591748A1 (ru) | Модуляторы p2x7 | |
| EA201491357A1 (ru) | Анти-lrp5 антитела и способы их применения | |
| BR112015004936A2 (pt) | composição farmacêutica revestida contendo regorafenib | |
| MA34075B1 (fr) | Composition pharmaceutique comprenant un dérivé pyrimidineone | |
| BR112014010782A2 (pt) | composições farmacêuticas de moduladores de receptor de androgênio seletivos e aplicações das mesmas | |
| UY34141A (es) | Composiciones de limpieza de sal líquida | |
| EP2709451A4 (en) | POSITIVE ALLOSTERIC N-NETWORKED LACTAM M1 RECEPTOR MODULATORS | |
| UY34158A (es) | Composicion herbicida | |
| PH12015500104A1 (en) | Chemical compounds | |
| DK2606042T3 (da) | Disubstituerede tetrahydrofuranyl-forbindelser som antagonister af bradykinin-b1-receptor | |
| EA201400444A1 (ru) | Производные 2-оксопиперидинила | |
| IL231439A0 (en) | Ethynyl derivatives as metabotropic glutamate receptor modulators | |
| EP2736523A4 (en) | PROTEASE ACTIVATED RECEPTOR MODULATORS | |
| UY34099A (es) | ?composición de agentes de coalescencia?. |