CR20140156A - Moduladores selectivos del receptor andrógeno - Google Patents

Moduladores selectivos del receptor andrógeno

Info

Publication number
CR20140156A
CR20140156A CR20140156A CR20140156A CR20140156A CR 20140156 A CR20140156 A CR 20140156A CR 20140156 A CR20140156 A CR 20140156A CR 20140156 A CR20140156 A CR 20140156A CR 20140156 A CR20140156 A CR 20140156A
Authority
CR
Costa Rica
Prior art keywords
selective modulators
androgen
receiver selective
androgen receiver
modulators
Prior art date
Application number
CR20140156A
Other languages
English (en)
Inventor
Prabhakar Kondaji Jadhav
Ashraf Saeed
Jonathan Edward Green
Venkatesh Krishnan
Donald Paul Matthews
Gregory Alan Stephenson
Original Assignee
Lilly Co Eli
Memory Pharm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47046879&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR20140156(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli, Memory Pharm Corp filed Critical Lilly Co Eli
Publication of CR20140156A publication Critical patent/CR20140156A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/14—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06—Anabolic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/22—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a nuevos moduladores del receptor andrógeno selectivos y sus sales y composiciones farmacéuticas de los mismos.
CR20140156A 2011-10-13 2014-04-04 Moduladores selectivos del receptor andrógeno CR20140156A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161546711P 2011-10-13 2011-10-13

Publications (1)

Publication Number Publication Date
CR20140156A true CR20140156A (es) 2014-05-16

Family

ID=47046879

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20140156A CR20140156A (es) 2011-10-13 2014-04-04 Moduladores selectivos del receptor andrógeno

Country Status (27)

Country Link
US (1) US8658693B2 (es)
EP (1) EP2766350B1 (es)
JP (1) JP6002228B2 (es)
KR (1) KR20140067102A (es)
CN (1) CN103842348B (es)
AP (1) AP2014007548A0 (es)
AR (1) AR088082A1 (es)
AU (1) AU2012321113B2 (es)
BR (1) BR112014008668A2 (es)
CA (1) CA2847889A1 (es)
CL (1) CL2014000895A1 (es)
CO (1) CO6910195A2 (es)
CR (1) CR20140156A (es)
DO (1) DOP2014000075A (es)
EA (1) EA201490519A1 (es)
EC (1) ECSP14013305A (es)
ES (1) ES2626820T3 (es)
GT (1) GT201400067A (es)
IL (1) IL231440A0 (es)
MX (1) MX2014004558A (es)
PE (1) PE20141669A1 (es)
PL (1) PL2766350T3 (es)
PT (1) PT2766350T (es)
SG (1) SG11201401794YA (es)
TN (1) TN2014000136A1 (es)
TW (1) TWI449686B (es)
WO (1) WO2013055577A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140045856A1 (en) 2012-07-31 2014-02-13 Boehringer Ingelheim International Gmbh 4-Methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalenes
TW201534586A (zh) * 2013-06-11 2015-09-16 Orion Corp 新穎ｃｙｐ１７抑制劑／抗雄激素劑
EP3077383B1 (en) 2013-12-04 2018-08-22 Evotec International GmbH Sulfoximine substituted quinazolines for pharmaceutical compositions
US9682960B2 (en) 2013-12-19 2017-06-20 Endorecherche, Inc. Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety
JP6479854B2 (ja) 2014-05-07 2019-03-06 エヴォテック・インターナショナル・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＥｖｏｔｅｃ Ｉｎｔｅｒｎａｔｉｏｎａｌ ＧｍｂＨ 医薬組成物のためのスルホキシイミン置換キナゾリン
MD3497103T2 (ro) 2016-08-15 2021-08-31 Pfizer Inhibitori de piridopirimidinonă CDK2/4/6
CA3034775C (en) 2016-09-02 2020-07-14 Suven Life Sciences Limited Muscarinic m1 receptor positive allosteric modulators
US11076596B2 (en) 2017-09-18 2021-08-03 Basf Se Substituted trifluoromethyloxadiazoles for combating phytopathogenic fungi

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3594405A (en) * 1968-05-17 1971-07-20 Du Pont Substituted pyranyl anilines as plant growth modifiers
ES2254611T3 (es) * 2001-05-11 2006-06-16 Pfizer Products Inc. Derivados de tiazol.
US8519158B2 (en) * 2004-03-12 2013-08-27 Ligand Pharmaceuticals Incorporated Androgen receptor modulator compounds and methods
ES2314922T3 (es) * 2005-05-13 2009-03-16 Eli Lilly And Company N-arilpirrolidinas sustituidas como moduladores selectivos del receptor de androgenos.
RU2008126228A (ru) * 2005-11-30 2010-01-10 Астеллас Фарма Инк. (Jp) 2-аминобензамидное производное
EP2146967A2 (en) * 2007-04-16 2010-01-27 Serenex, Inc. Tetrahydroindole and tetrahydroindazole derivatives
US8190467B2 (en) * 2007-10-19 2012-05-29 Michelle Letendre-Hedlund Methods of identifying environmentally friendly businesses or individuals
MX2010009162A (es) * 2008-02-22 2010-12-21 Radius Health Inc Moduladores selectivos del receptor de androgeno.

Also Published As

Publication number Publication date
EA201490519A1 (ru) 2014-09-30
DOP2014000075A (es) 2014-06-01
CA2847889A1 (en) 2013-04-18
TW201329026A (zh) 2013-07-16
CL2014000895A1 (es) 2014-08-22
PE20141669A1 (es) 2014-11-08
CN103842348B (zh) 2015-08-19
WO2013055577A1 (en) 2013-04-18
KR20140067102A (ko) 2014-06-03
US8658693B2 (en) 2014-02-25
AP2014007548A0 (en) 2014-03-31
GT201400067A (es) 2015-02-27
CN103842348A (zh) 2014-06-04
AR088082A1 (es) 2014-05-07
US20130217762A1 (en) 2013-08-22
AU2012321113B2 (en) 2015-07-09
CO6910195A2 (es) 2014-03-31
AU2012321113A1 (en) 2014-03-27
MX2014004558A (es) 2014-08-01
PT2766350T (pt) 2017-05-22
SG11201401794YA (en) 2014-09-26
TWI449686B (zh) 2014-08-21
JP6002228B2 (ja) 2016-10-05
PL2766350T3 (pl) 2017-08-31
EP2766350B1 (en) 2017-04-05
EP2766350A1 (en) 2014-08-20
ES2626820T3 (es) 2017-07-26
ECSP14013305A (es) 2014-05-31
TN2014000136A1 (en) 2015-07-01
JP2014530818A (ja) 2014-11-20
BR112014008668A2 (pt) 2017-04-25
IL231440A0 (en) 2014-04-30

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