MX2014004558A - Moduladores selectivos del receptor de androgeno. - Google Patents

Moduladores selectivos del receptor de androgeno.

Info

Publication number
MX2014004558A
MX2014004558A MX2014004558A MX2014004558A MX2014004558A MX 2014004558 A MX2014004558 A MX 2014004558A MX 2014004558 A MX2014004558 A MX 2014004558A MX 2014004558 A MX2014004558 A MX 2014004558A MX 2014004558 A MX2014004558 A MX 2014004558A
Authority
MX
Mexico
Prior art keywords
androgen receptor
receptor modulators
selective androgen
salts
selective
Prior art date
Application number
MX2014004558A
Other languages
English (en)
Inventor
Gregory Alan Stephenson
Prabhakar Kondaji Jadhav
Ashraf Saeed
Jonathan Edward Green
Venkatesh Krishnan
Donald Paul Matthews
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47046879&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2014004558(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MX2014004558A publication Critical patent/MX2014004558A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/14—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06—Anabolic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/22—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a nuevos moduladores del receptor de andrógeno selectivos y sus sales y composiciones farmacéuticas de los mismos. (ver Fórmula).
MX2014004558A 2011-10-13 2012-10-05 Moduladores selectivos del receptor de androgeno. MX2014004558A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161546711P 2011-10-13 2011-10-13
PCT/US2012/058824 WO2013055577A1 (en) 2011-10-13 2012-10-05 Selective androgen receptor modulators

Publications (1)

Publication Number Publication Date
MX2014004558A true MX2014004558A (es) 2014-08-01

Family

ID=47046879

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014004558A MX2014004558A (es) 2011-10-13 2012-10-05 Moduladores selectivos del receptor de androgeno.

Country Status (27)

Country Link
US (1) US8658693B2 (es)
EP (1) EP2766350B1 (es)
JP (1) JP6002228B2 (es)
KR (1) KR20140067102A (es)
CN (1) CN103842348B (es)
AP (1) AP2014007548A0 (es)
AR (1) AR088082A1 (es)
AU (1) AU2012321113B2 (es)
BR (1) BR112014008668A2 (es)
CA (1) CA2847889A1 (es)
CL (1) CL2014000895A1 (es)
CO (1) CO6910195A2 (es)
CR (1) CR20140156A (es)
DO (1) DOP2014000075A (es)
EA (1) EA201490519A1 (es)
EC (1) ECSP14013305A (es)
ES (1) ES2626820T3 (es)
GT (1) GT201400067A (es)
IL (1) IL231440A0 (es)
MX (1) MX2014004558A (es)
PE (1) PE20141669A1 (es)
PL (1) PL2766350T3 (es)
PT (1) PT2766350T (es)
SG (1) SG11201401794YA (es)
TN (1) TN2014000136A1 (es)
TW (1) TWI449686B (es)
WO (1) WO2013055577A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140045856A1 (en) 2012-07-31 2014-02-13 Boehringer Ingelheim International Gmbh 4-Methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalenes
TW201534586A (zh) * 2013-06-11 2015-09-16 Orion Corp 新穎ｃｙｐ１７抑制劑／抗雄激素劑
CA2929742C (en) 2013-12-04 2022-09-20 Evotec International Gmbh Sulfoximine substituted quinazolines for pharmaceutical compositions
US9682960B2 (en) 2013-12-19 2017-06-20 Endorecherche, Inc. Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety
EP3140300B1 (en) 2014-05-07 2019-08-14 Evotec International GmbH Sulfoximine substituted quinazolines for pharmaceutical compositions
DK3497103T3 (da) 2016-08-15 2021-06-14 Pfizer Pyridopyrimdinon-cdk2/4/6-inhibitorer
CN109952302B (zh) 2016-09-02 2020-11-24 苏文生命科学有限公司 毒蕈碱m1受体正向别构调节剂
BR112020004441B1 (pt) 2017-09-18 2024-01-16 Basf Se Compostos da fórmula i, composição agroquímica, semente revestida, uso de compostos e método não-terapêutico de combate de fungos

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3594405A (en) * 1968-05-17 1971-07-20 Du Pont Substituted pyranyl anilines as plant growth modifiers
ATE315555T1 (de) * 2001-05-11 2006-02-15 Pfizer Prod Inc Thiazolderivate und ihre verwendung als cdk- inhibitoren
US8519158B2 (en) * 2004-03-12 2013-08-27 Ligand Pharmaceuticals Incorporated Androgen receptor modulator compounds and methods
MX2007014053A (es) * 2005-05-13 2008-02-05 Lilly Co Eli N-arilpirrolidinas substituidas como moduladores selectivos de receptor de androgeno.
EP1955697B1 (en) * 2005-11-30 2012-05-02 Astellas Pharma Inc. 2-aminobenzamide derivatives as vanilloid receptor 1 (vr1) inhibitors useful for the treatment of pain or bladder function disorder
EP2146967A2 (en) * 2007-04-16 2010-01-27 Serenex, Inc. Tetrahydroindole and tetrahydroindazole derivatives
CN101828200A (zh) * 2007-10-19 2010-09-08 米歇尔·勒唐德尔-赫德伦 标识环境友好企业或个人的方法
EP2260028B1 (en) * 2008-02-22 2014-05-07 Radius Health, Inc. Selective androgen receptor modulators

Also Published As

Publication number Publication date
DOP2014000075A (es) 2014-06-01
TN2014000136A1 (en) 2015-07-01
CN103842348A (zh) 2014-06-04
WO2013055577A1 (en) 2013-04-18
CL2014000895A1 (es) 2014-08-22
TWI449686B (zh) 2014-08-21
CN103842348B (zh) 2015-08-19
SG11201401794YA (en) 2014-09-26
EP2766350A1 (en) 2014-08-20
ES2626820T3 (es) 2017-07-26
GT201400067A (es) 2015-02-27
TW201329026A (zh) 2013-07-16
KR20140067102A (ko) 2014-06-03
PL2766350T3 (pl) 2017-08-31
PT2766350T (pt) 2017-05-22
PE20141669A1 (es) 2014-11-08
EA201490519A1 (ru) 2014-09-30
AR088082A1 (es) 2014-05-07
AU2012321113B2 (en) 2015-07-09
ECSP14013305A (es) 2014-05-31
US8658693B2 (en) 2014-02-25
EP2766350B1 (en) 2017-04-05
IL231440A0 (en) 2014-04-30
US20130217762A1 (en) 2013-08-22
JP6002228B2 (ja) 2016-10-05
JP2014530818A (ja) 2014-11-20
CA2847889A1 (en) 2013-04-18
AP2014007548A0 (en) 2014-03-31
CO6910195A2 (es) 2014-03-31
AU2012321113A1 (en) 2014-03-27
BR112014008668A2 (pt) 2017-04-25
CR20140156A (es) 2014-05-16

Similar Documents

Publication Publication Date Title
ZA202003200B (en) Compositions, methods, and systems for the synthesis and use of imaging agents
GB201017345D0 (en) Receptor antagonists
TN2014000136A1 (en) Selective androgen receptor modulators
HK1198902A1 (en) Devices, systems and methods for the whitening of teeth
MX2012015188A (es) Composiciones de liberacion controlada con efecto de alimentos reducido.
JO3755B1 (ar) تركيبات تستوستيرون
IN2014KN02993A (es)
MX2015008588A (es) Composiciones y metodos para la transfeccion de polinucleótidos.
IN2015DN03132A (es)
MY165088A (en) Pharmaceutical compositions comprising alisporivir
HK1203068A1 (en) Systems and methods for generating germicidal compositions
GB201320570D0 (en) Highly viscous disinfectant composition
TN2013000218A1 (en) Pharmaceutical compositions comprising alisporivir
MX2015001134A (es) Compuestos terapeuticos.
UA80618U (en) Use of n-steroylethanolamine as radiomodifier
UA72478U (ru) Применение полентара как средства фригопротекторного действия

Legal Events

Date Code Title Description
FA Abandonment or withdrawal