EA201290790A1 - Биоадгезивные композиции местных анестетиков - Google Patents
Биоадгезивные композиции местных анестетиковInfo
- Publication number
- EA201290790A1 EA201290790A1 EA201290790A EA201290790A EA201290790A1 EA 201290790 A1 EA201290790 A1 EA 201290790A1 EA 201290790 A EA201290790 A EA 201290790A EA 201290790 A EA201290790 A EA 201290790A EA 201290790 A1 EA201290790 A1 EA 201290790A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- local anesthetics
- bioadhesive compositions
- compositions
- bioadhesive
- swelling
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
- A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
- A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
- A61L2/04—Heat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2103/00—Materials or objects being the target of disinfection or sterilisation
- A61L2103/05—Living organisms or biological materials
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Anesthesiology (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1050322 | 2010-04-01 | ||
| US32542510P | 2010-04-19 | 2010-04-19 | |
| PCT/EP2011/055025 WO2011121082A1 (en) | 2010-04-01 | 2011-03-31 | Bioadhesive compositions of local anaesthetics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201290790A1 true EA201290790A1 (ru) | 2013-04-30 |
Family
ID=44278867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201290790A EA201290790A1 (ru) | 2010-04-01 | 2011-03-31 | Биоадгезивные композиции местных анестетиков |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20130079371A1 (https=) |
| EP (1) | EP2552409A1 (https=) |
| JP (1) | JP2013523694A (https=) |
| KR (1) | KR20130080435A (https=) |
| CN (1) | CN102869344A (https=) |
| AU (1) | AU2011234415C1 (https=) |
| BR (1) | BR112012024885A2 (https=) |
| CA (1) | CA2794280A1 (https=) |
| CL (1) | CL2012002705A1 (https=) |
| EA (1) | EA201290790A1 (https=) |
| IL (1) | IL222225A0 (https=) |
| MX (1) | MX2012011261A (https=) |
| NZ (1) | NZ602540A (https=) |
| PH (1) | PH12012501887A1 (https=) |
| SG (1) | SG184072A1 (https=) |
| WO (1) | WO2011121082A1 (https=) |
| ZA (1) | ZA201206989B (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9642912B2 (en) | 2006-03-06 | 2017-05-09 | Crescita Therapeutics Inc. | Topical formulations for treating skin conditions |
| US9308181B2 (en) | 2006-03-06 | 2016-04-12 | Nuvo Research Inc. | Topical formulations, systems and methods |
| WO2010033726A2 (en) | 2008-09-17 | 2010-03-25 | The Brigham And Women's Hospital, Inc. | Drug delivery composition comprising a self-assembled gelator |
| JP2013540757A (ja) | 2010-09-24 | 2013-11-07 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド | カプセル化された作用物質の放出を制御する能力を有するナノ構造ゲル |
| JP6363115B2 (ja) * | 2013-02-28 | 2018-07-25 | ミラ ファーマ コーポレイション | 注射可能局所麻酔半固体製剤およびその組成物 |
| US10220093B2 (en) | 2013-02-28 | 2019-03-05 | Mira Pharma Corporation | Long-acting semi-solid lipid formulations |
| GB201317718D0 (en) * | 2013-10-07 | 2013-11-20 | Buzzz Pharmaceuticals Ltd | Novel formulation |
| AU2016237984B2 (en) | 2015-03-25 | 2019-01-31 | Terumo Kabushiki Kaisha | Gel type local anesthetic agent and gel type local anesthetic preparation using same |
| WO2017082121A1 (ja) | 2015-11-12 | 2017-05-18 | テルモ株式会社 | 徐放性局所投与剤 |
| WO2018144991A1 (en) | 2017-02-03 | 2018-08-09 | The Brigham And Women's Hospital, Inc. | Self-assembled gels formed with anti-retroviral drugs, prodrugs thereof, and pharmaceutical uses thereof |
| EP3621594A1 (en) * | 2017-05-08 | 2020-03-18 | Alivio Therapeutics, Inc. | Formulation of nanostructured gels for increased agent loading and adhesion |
| US10561606B2 (en) | 2017-12-06 | 2020-02-18 | Mira Pharma Corporation | Injectable long-acting local anesthetic semi-solid gel formulations |
| EP3720420B1 (en) | 2017-12-06 | 2025-08-27 | HuZhou Hui Zhong Ji Shi Biotechnology Co., Ltd. | Injectable long-acting local anesthetic semi-solid gel formulations |
| US11426418B2 (en) | 2017-12-06 | 2022-08-30 | Mira Pharma Corporation | Injectable long-acting semi-solid gel formulations |
| CA3113948A1 (en) | 2018-10-11 | 2020-04-16 | Alivio Therapeutics, Inc. | Non-injectable hydrogel formulations for smart release |
| EP4284272A4 (en) * | 2021-01-29 | 2024-12-25 | Insitu Biologics, Inc. | COMPOSITIONS AND METHODS OF SUSTAINED TREATMENT OF PAIN |
| CN118697692B (zh) * | 2024-06-27 | 2024-11-26 | 山东中医药大学附属医院 | 一种防苦麻醉胶浆剂、方法及应用 |
| CN119587525B (zh) * | 2024-11-07 | 2025-09-05 | 海南三帝制药有限公司 | 一种二甲卡因复合制剂及其制备方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5045553A (en) * | 1987-06-24 | 1991-09-03 | Fujisawa Pharmaceutical Company, Ltd. | Pharmaceutical composition for percutaneous drug absorption and percutaneous drug absorption promoter |
| JP4137179B2 (ja) * | 1994-03-30 | 2008-08-20 | ジーエス ディベロップメント エービー | 生物付着性物質としての脂肪酸エステルの使用 |
| SE9601421D0 (sv) * | 1996-04-12 | 1996-04-12 | Astra Ab | New composition |
| PL332724A1 (en) * | 1996-10-14 | 1999-10-11 | Kowa Co | Local anaesthetic for extracorporeal use |
| US20040001889A1 (en) * | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
| WO2004071398A2 (en) * | 2003-02-17 | 2004-08-26 | Cipla Ltd | Pharmaceutical patch |
| US20050084508A1 (en) | 2003-07-22 | 2005-04-21 | Vancaillie Thierry G. | Topical anesthesia formulation for bodily cavities |
| JP5144277B2 (ja) * | 2005-01-14 | 2013-02-13 | カムルス エービー | 局所用生体付着性製剤 |
| JP4931369B2 (ja) | 2005-05-31 | 2012-05-16 | ポーラ化成工業株式会社 | リポソームおよびそれを含む処置用の組成物 |
| MX2008004094A (es) * | 2005-09-27 | 2009-02-27 | Efrat Biopolymers Ltd | Composiciones de polimero inyectables hidrofobicas, gelificantes. |
| GB0524958D0 (en) * | 2005-12-07 | 2006-01-18 | Pharmakodex Ltd | Transdermal administration of active agents |
| US20070280972A1 (en) * | 2006-04-25 | 2007-12-06 | Zars, Inc. | Adhesive solid gel-forming formulations for dermal drug delivery |
| US20070269386A1 (en) * | 2006-05-16 | 2007-11-22 | Per Steen | New product and use and manufacture thereof |
| JP5181320B2 (ja) * | 2006-10-18 | 2013-04-10 | ニチバン株式会社 | 皮膚刺激の少ない経皮吸収型製剤 |
| US9918934B2 (en) | 2006-12-12 | 2018-03-20 | Edgar Joel Acosta-Zara | Linker-based lecithin microemulsion delivery vehicles |
| US20090247494A1 (en) | 2008-04-01 | 2009-10-01 | Phillip Mark Kofsky | Omega-3 essential fatty acid composition and method for treatment of anal and colon-rectal disorders |
-
2011
- 2011-03-31 MX MX2012011261A patent/MX2012011261A/es not_active Application Discontinuation
- 2011-03-31 WO PCT/EP2011/055025 patent/WO2011121082A1/en not_active Ceased
- 2011-03-31 EP EP11711566A patent/EP2552409A1/en not_active Withdrawn
- 2011-03-31 NZ NZ602540A patent/NZ602540A/en not_active IP Right Cessation
- 2011-03-31 AU AU2011234415A patent/AU2011234415C1/en not_active Ceased
- 2011-03-31 EA EA201290790A patent/EA201290790A1/ru unknown
- 2011-03-31 US US13/638,519 patent/US20130079371A1/en not_active Abandoned
- 2011-03-31 SG SG2012068250A patent/SG184072A1/en unknown
- 2011-03-31 BR BR112012024885A patent/BR112012024885A2/pt not_active IP Right Cessation
- 2011-03-31 CN CN2011800166567A patent/CN102869344A/zh active Pending
- 2011-03-31 PH PH1/2012/501887A patent/PH12012501887A1/en unknown
- 2011-03-31 CA CA2794280A patent/CA2794280A1/en not_active Abandoned
- 2011-03-31 KR KR1020127028642A patent/KR20130080435A/ko not_active Withdrawn
- 2011-03-31 JP JP2013501854A patent/JP2013523694A/ja active Pending
-
2012
- 2012-09-18 ZA ZA2012/06989A patent/ZA201206989B/en unknown
- 2012-09-27 IL IL222225A patent/IL222225A0/en unknown
- 2012-09-27 CL CL2012002705A patent/CL2012002705A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA201206989B (en) | 2014-04-30 |
| BR112012024885A2 (pt) | 2016-06-21 |
| AU2011234415A1 (en) | 2012-10-18 |
| CA2794280A1 (en) | 2011-10-06 |
| PH12012501887A1 (en) | 2012-12-17 |
| SG184072A1 (en) | 2012-10-30 |
| AU2011234415B2 (en) | 2014-04-10 |
| IL222225A0 (en) | 2012-12-31 |
| AU2011234415C1 (en) | 2014-07-10 |
| JP2013523694A (ja) | 2013-06-17 |
| WO2011121082A1 (en) | 2011-10-06 |
| EP2552409A1 (en) | 2013-02-06 |
| NZ602540A (en) | 2014-05-30 |
| KR20130080435A (ko) | 2013-07-12 |
| MX2012011261A (es) | 2012-12-05 |
| CL2012002705A1 (es) | 2013-02-01 |
| US20130079371A1 (en) | 2013-03-28 |
| CN102869344A (zh) | 2013-01-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EA201290790A1 (ru) | Биоадгезивные композиции местных анестетиков | |
| JOP20180103B1 (ar) | التركيب الصيدلاني للكاربيتوسين | |
| CY1110648T1 (el) | Ενωσεις τροπανιου | |
| CL2011000087A1 (es) | Compuestos derivados de heteroarilo sustituido, inhibidores de los receptores dgat1; composicion farmaceutica; y su uso para tratar la diabetes tipo ll y obesidad. | |
| EA201100037A1 (ru) | Органические соединения | |
| EA201290789A1 (ru) | Термогелеобразующие композиции анестетиков | |
| EA201270254A1 (ru) | Производные 5-фторпиримидинона | |
| EA201390793A1 (ru) | Способ получения фармацевтической композиции, содержащей ипн | |
| EP2556163A4 (en) | GLYCANE WITH HIGH MANNOSE SHARE | |
| CL2009000426A1 (es) | Compuestos derivados de carbociclil/heterociclil-piridin-2-il-urea, inhibidores de topoisomerasa iv bacteriana; composicion farmaceutica; y su uso para el tratamiento de infecciones bacterianas | |
| EA201070237A1 (ru) | Четвертичные опиоидные карбоксамиды | |
| MX336741B (es) | Composiciones farmaceuticas de moduladores de c-met. | |
| CL2013002171A1 (es) | Composicion fungicida y bactericida que comprende compuestos organicos volatiles de origen natural; uso de la composición. | |
| BR112013011448A2 (pt) | composto, composição farnmacêutica, e, uso do composto | |
| CY1122115T1 (el) | Παραγωγα ν1-ακυλο-5-φθοροπυριμιδινονης | |
| EA201070327A1 (ru) | Катехоламиновые производные и их пролекарства | |
| MX2012007933A (es) | Composiciones de dexmedetomidina transdermicas topicas y metodos para su uso. | |
| CL2012000508A1 (es) | Composicion para la aplicacion en cultivos agricolas al aire libre o invernaderos que comprende zeolita, y aditivos; uso de la composicion para aumentar el rendimiento de los cultivos agricolas. | |
| UA111744C2 (uk) | ЗАМІЩЕНІ ПІРИДОПІРАЗИНИ ЯК ІНГІБІТОРИ Syk | |
| CL2012003681A1 (es) | Compuestos derivados de piperidina; composicion farmaceutica; y su uso como inhibidores de acetil-coa carboxilasa para el tratamiento de trastornos metabolicos, tales como obesidad y diabetes. | |
| PT2345628T (pt) | Uso de extratos naturais de materiais tanínicos e não-tanínicos para melhorar a fertilidade do solo e proporcionar um efeito de arranque sobre culturas, e um fitocomposto tanínico e não-tanínico para este efeito | |
| CL2009000388A1 (es) | Compuestos derivados de biciclos nitrogenados; proceso de preparacion; composicion farmaceutica; y su uso para tratar el dolor cronico que surge por inflamacion o neuropatia. | |
| BRPI0920355A2 (pt) | composições farmacêuticas tópicas estáveis de ozenoxacina e uso de ozenoxacina | |
| DOP2010000329A (es) | Inhibidores de la renina | |
| BR112014004263A2 (pt) | composições fixadoras de cabelo |