EA201270154A1 - Металлические наночастицы, их получение и применение - Google Patents

Металлические наночастицы, их получение и применение

Info

Publication number
EA201270154A1
EA201270154A1 EA201270154A EA201270154A EA201270154A1 EA 201270154 A1 EA201270154 A1 EA 201270154A1 EA 201270154 A EA201270154 A EA 201270154A EA 201270154 A EA201270154 A EA 201270154A EA 201270154 A1 EA201270154 A1 EA 201270154A1
Authority
EA
Eurasian Patent Office
Prior art keywords
application
nanoparticles
receiving
metal nanoparticles
field
Prior art date
Application number
EA201270154A
Other languages
English (en)
Other versions
EA020942B1 (ru
Inventor
Лоран Леви
Аньес Поттье
Лоранс Пуль
Лоранс Маджиорелла
Original Assignee
Нанобиотикс
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Нанобиотикс filed Critical Нанобиотикс
Publication of EA201270154A1 publication Critical patent/EA201270154A1/ru
Publication of EA020942B1 publication Critical patent/EA020942B1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092Details
    • A61N2005/1098Enhancing the effect of the particle by an injected agent or implanted device

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Настоящая заявка относится к активируемым наночастицам, которые могут использоваться в области здравоохранения, в частности в области здравоохранения человека, для того чтобы нарушать, изменять или разрушать клетки-мишени, ткани или органы. В особенности данная заявка относится к наночастицам, которые могут оказывать значительно эффективное терапевтическое действие, когда подвергаются воздействию ионизирующих излучений. Наночастица настоящего изобретения является металлической наночастицей, самый большой размер которой находится в диапазоне от примерно 80 до 105 нм, из металла, имеющего атомный номер (Z), по меньшей мере 25. Настоящее изобретение также относится к фармацевтическим композициям, содержащим совокупность вышеуказанных наночастиц, а также к их применению.
EA201270154A 2009-07-10 2010-07-09 Металлические наночастицы, их получение и применение EA020942B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22457609P 2009-07-10 2009-07-10
EP09165157A EP2275137A1 (en) 2009-07-10 2009-07-10 Metallic nanoparticles, preparation and uses thereof
PCT/EP2010/059871 WO2011003999A1 (en) 2009-07-10 2010-07-09 Metallic nanoparticles, preparation and uses thereof

Publications (2)

Publication Number Publication Date
EA201270154A1 true EA201270154A1 (ru) 2012-07-30
EA020942B1 EA020942B1 (ru) 2015-02-27

Family

ID=41110399

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201270154A EA020942B1 (ru) 2009-07-10 2010-07-09 Металлические наночастицы, их получение и применение

Country Status (25)

Country Link
US (2) US9700621B2 (ru)
EP (3) EP2275137A1 (ru)
JP (1) JP5739883B2 (ru)
KR (1) KR101670757B1 (ru)
CN (1) CN102470173B (ru)
AU (1) AU2010270225B2 (ru)
BR (2) BR112012000530B8 (ru)
CA (1) CA2765290C (ru)
CY (1) CY1118600T1 (ru)
DK (2) DK3178494T3 (ru)
EA (1) EA020942B1 (ru)
ES (2) ES2837412T3 (ru)
HR (2) HRP20170175T1 (ru)
HU (2) HUE031796T2 (ru)
IL (1) IL217287A (ru)
LT (1) LT2451481T (ru)
MA (1) MA33516B1 (ru)
MX (2) MX347606B (ru)
NZ (1) NZ597564A (ru)
PL (2) PL2451481T3 (ru)
PT (2) PT3178494T (ru)
SG (2) SG177611A1 (ru)
SI (1) SI2451481T1 (ru)
WO (1) WO2011003999A1 (ru)
ZA (1) ZA201200902B (ru)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102051248B1 (ko) 2009-07-08 2019-12-02 클레네 나노메디슨, 인크. 의학적 치료를 위한 신규한 금계 나노결정 및 이를 위한 전기화학 제조 방법
EP2275137A1 (en) * 2009-07-10 2011-01-19 Nanobiotix Metallic nanoparticles, preparation and uses thereof
US20120190979A1 (en) 2011-01-24 2012-07-26 Actium BioSystems, LLC System for automatically amending energy field characteristics in the application of an energy field to a living organism for treatment of invasive agents
KR102069907B1 (ko) * 2011-08-26 2020-01-23 엔도마그네틱스 엘티디 체강 및 공동형 부위에 있는 암을 치료하기 위한 에너지 필드 발생 장치
AU2012351537B2 (en) 2011-12-16 2017-03-02 Nanobiotix Nanoparticles comprising metallic and hafnium oxide materials, preparation and uses thereof
US10098952B2 (en) * 2013-01-25 2018-10-16 Nanobiotix Inorganic nanoparticles compositions in combination with ionizing radiations for treating cancer
JP6387400B2 (ja) * 2013-05-30 2018-09-05 ナノビオティックスNanobiotix 医薬組成物、その製造および使用
WO2014202723A1 (en) * 2013-06-20 2014-12-24 Nanobiotix Compositions and methods for use in medical diagnosis
TWI689310B (zh) 2014-07-11 2020-04-01 巨生生醫股份有限公司 治療鐵缺乏症之方法
JP6778371B2 (ja) * 2015-01-23 2020-11-04 ミヨシ油脂株式会社 金微粒子マトリックスメタロプロテアーゼ阻害剤
WO2016189125A1 (en) 2015-05-28 2016-12-01 Nanobiotix Nanoparticles for use as a therapeutic vaccine
DE102017101057A1 (de) * 2017-01-20 2018-07-26 Fraunhofer-Institut für Angewandte Polymerforschung IAP Zwitterionische Nanopartikel
JP7376901B2 (ja) * 2017-11-13 2023-11-09 国立大学法人北海道大学 修飾金属ナノ粒子及び医薬組成物
CN110883341B (zh) * 2018-09-11 2021-03-30 清华大学 金纳米团簇制备方法
WO2021060498A1 (ja) * 2019-09-27 2021-04-01 国立大学法人京都大学 多孔性シリカを含むナノ粒子およびその製造方法、ならびに放射線治療用医薬組成物
EP4157457A1 (en) * 2020-05-26 2023-04-05 Nanobiotix Nanoparticles, ionizing radiation and innovative therapeutic combinations thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000006244A2 (en) * 1998-07-30 2000-02-10 Hainfeld James F Loading metal particles into cell membrane vesicles and metal particle use for imaging and therapy
US20070031337A1 (en) * 2004-06-22 2007-02-08 Reinhard Schulte Nanoparticle enhanced proton computed tomography and proton therapy
DE102007040934A1 (de) 2007-08-30 2009-03-05 Man Diesel A/S Verfahren und Vorrichtung zur Reinigung von Abgas
EP2130553A1 (en) * 2008-06-05 2009-12-09 Nanobiotix Inorganic nanoparticles of high density to destroy cells in-vivo
EP2275137A1 (en) * 2009-07-10 2011-01-19 Nanobiotix Metallic nanoparticles, preparation and uses thereof

Also Published As

Publication number Publication date
US20120203050A1 (en) 2012-08-09
KR20120052979A (ko) 2012-05-24
US10391174B2 (en) 2019-08-27
CY1118600T1 (el) 2017-07-12
BR122019025997B8 (pt) 2021-07-27
MA33516B1 (fr) 2012-08-01
BR122019025997B1 (pt) 2020-11-24
DK2451481T3 (en) 2017-03-06
US9700621B2 (en) 2017-07-11
SG10201403832YA (en) 2014-09-26
PT3178494T (pt) 2020-12-21
EP2451481B1 (en) 2017-01-25
BR112012000530A8 (pt) 2017-12-26
CA2765290C (en) 2018-02-13
US20170296661A1 (en) 2017-10-19
EA020942B1 (ru) 2015-02-27
MX347606B (es) 2017-05-04
HRP20202005T1 (hr) 2021-02-19
SG177611A1 (en) 2012-02-28
EP2451481A1 (en) 2012-05-16
PL2451481T3 (pl) 2017-07-31
IL217287A (en) 2016-05-31
HRP20170175T1 (hr) 2017-06-02
HUE052686T2 (hu) 2021-05-28
BR112012000530B1 (pt) 2021-01-19
BR112012000530B8 (pt) 2021-05-25
CN102470173B (zh) 2015-04-22
AU2010270225B2 (en) 2014-08-28
CA2765290A1 (en) 2011-01-13
NZ597564A (en) 2013-06-28
ES2837412T3 (es) 2021-06-30
WO2011003999A1 (en) 2011-01-13
LT2451481T (lt) 2017-05-25
EP3178494B1 (en) 2020-10-14
CN102470173A (zh) 2012-05-23
EP2275137A1 (en) 2011-01-19
PT2451481T (pt) 2017-03-06
AU2010270225A1 (en) 2012-01-19
HUE031796T2 (en) 2017-08-28
ZA201200902B (en) 2012-10-31
PL3178494T3 (pl) 2021-04-06
KR101670757B1 (ko) 2016-10-31
EP3178494A1 (en) 2017-06-14
IL217287A0 (en) 2012-02-29
MX2012000285A (es) 2012-02-08
SI2451481T1 (sl) 2017-04-26
JP2012532847A (ja) 2012-12-20
BR112012000530A2 (pt) 2016-11-16
JP5739883B2 (ja) 2015-06-24
DK3178494T3 (da) 2020-12-21
ES2616628T3 (es) 2017-06-13

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Legal Events

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AZ KZ KG TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM BY MD